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Nikhil C Munshi
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Journal Articles

Development of hyperdiploidy starts at an early age and takes a decade to complete

Mehmet K. Samur, Anil Aktas Samur, Parth Shah, Joseph Park, Mariateresa Fulciniti, Masood A Shammas, Jill Corre, Kenneth C. Anderson, Giovanni Parmigiani, Hervé Avet-Loiseau, Nikhil C. Munshi
Journal: Blood
Blood blood.2024025250.
https://doi.org/10.1182/blood.2024025250
Published: 2024
Includes: Supplemental data
Journal Articles

Serum free light chains in a racially diverse population including African Americans and populations from South Africa

Luca Bertamini, Jean-Baptiste Alberge, David Jungpa Lee, Habib El-Khoury, Sungjae Kim, Grace Fleming, Ciara Suen Marie Murphy, Julia Colchie, Maya I Davis, Jacqueline Perry, Elizabeth D Lightbody, Sabine Allam, Lindokuhle N Goqwana, Vinitha Philip, Natalie Anne Smyth, NA, Dhananjay Sakrikar, Mark C Perkins, Stephen Harding, Derek Troske, Gad Getz, Elizabeth W Karlson, Nikhil C. Munshi, Kenneth C. Anderson, Lorenzo Trippa, Catherine R Marinac, Wenlong Carl Chen, Maureen Joffe, Irene M Ghobrial
Journal: Blood
Blood blood.2024026078.
https://doi.org/10.1182/blood.2024026078
Published: 2024
Includes: Supplemental data
Journal Articles

Biological and Clinical Significance of Endogenous and Chimeric Antigen Receptor (CAR) T Cell Immune Profiling in Relapsed/Refractory Multiple Myeloma (RRMM) Patients

Bruno Paiva, Irene Manrique, Ethan G. Thompson, Timothy B. Campbell, Camila Guerrero, Nathan Martin, Larry D Anderson, Jr., Jesus G Berdeja, Sagar Lonial, Noopur Raje, Yi Lin, Philippe Moreau, Jesús F. San-Miguel, Nikhil C. Munshi, Shari Kaiser
Journal: Blood
Blood (2024) 144 (Supplement 1): 900.
https://doi.org/10.1182/blood-2024-203007
Published: 2024
Journal Articles

Deciphering Drivers of Functional and Phenotypic Changes through Genome-Wide Screen (DRIVE-Genome) to Identify Genes Inducing Genomic Instability in Myeloma

Srikanth Talluri, Leutz Buon, Jiangning Zhao, Daniel Meglino, Chandraditya Chakraborty, Chengcheng Liao, Mehmet K. Samur, David E. Root, Masood A. Shammas, Nikhil C. Munshi
Journal: Blood
Blood (2024) 144 (Supplement 1): 4133.
https://doi.org/10.1182/blood-2024-210496
Published: 2024
Journal Articles

Isoform-Level Long Noncoding RNA Dependencies in Multiple Myeloma

Eugenio Morelli, Anil Aktas-Samur, Domenico Maisano, Claire Gao, Vanessa Favasuli, Dimitrios Papaioannou, Na Liu, Marcello Turi, Pietro Folino, Laure Vreux, Michela Cumerlato, Liang Cheng, Iannis Aifantis, Mariateresa Fulciniti, Kenneth C. Anderson, Annamaria Gulla, Mehmet K. Samur, Nikhil C. Munshi
Journal: Blood
Blood (2024) 144 (Supplement 1): 4130.
https://doi.org/10.1182/blood-2024-209546
Published: 2024
Journal Articles

Prolonged Persistence and Functional Activity of Anti-BCMA CAR-T Durcabtagene Autoleucel (PHE885) Manufactured Using the T-Charge™ Platform

Shuntaro Ikegawa, Adam S. Sperling, Sarah Nikiforow, Andrew Ghazi, Anthony Christidis, David Quinn, Dexiu Bu, Jennifer Mataraza, David Pearson, Allison Charles, Marc Credi, Nina Orwitz, Madisyn Strange, Rakuyo Tamada, Kevin M. Panaro, Casey Gervais, Michela Ansuinelli, Yohei Arihara, Rao Prabhala, Carol G. Reynolds, Robert Gentleman, Serena De Vita, Nikhil C. Munshi, Jerome Ritz
Journal: Blood
Blood (2024) 144 (Supplement 1): 149.
https://doi.org/10.1182/blood-2024-199890
Published: 2024
Journal Articles

The Mitochondrial Protease Clpp Is a Metabolic Vulnerability and an Immunogenic Trigger Against Multiple Myeloma

Tommaso Perini, Paola Zordan, Rossella Del Pizzo, Massimo Resnati, Ugo Orfanelli, Davide Stefanoni, Laura Cassina, Laura Oliva, Mehmet K. Samur, Lisa Viviani, Maria Materozzi, Matteo Trudu, Alessandra Boletta, Enrico Milan, Fabio Ciceri, Nikhil C. Munshi, Matteo Bellone, Simone Cenci
Journal: Blood
Blood (2024) 144 (Supplement 1): 765.
https://doi.org/10.1182/blood-2024-201364
Published: 2024
Journal Articles

PKMYT1 Kinase Is an Actionable Synthetically Lethal Target for Del17p Myeloma

Anais Schavgoulidze, Mariateresa Fulciniti, Giulia Giorgetti, Sabrina Maheo, Shuhui Deng, Vanessa Favasuli, Srikanth Talluri, Masood A. Shammas, Luka Pavageau, Anil Aktas-Samur, Mehmet K. Samur, Herve Avet-Loiseau, Jill Corre, Nikhil C. Munshi
Journal: Blood
Blood (2024) 144 (Supplement 1): 764.
https://doi.org/10.1182/blood-2024-199692
Published: 2024
Journal Articles

Single-Cell Whole-Genome Sequencing of Circulating Tumor Cells in Relapsed/Refractory Multiple Myeloma Patients Receiving BCMA- or GPRC5D-Targeted Immunotherapies

Rosa Toenges, Jean-Baptiste Alberge, Francesco Corrado, Nayda Bidikian, David M. Cordas Dos Santos, Ankit K. Dutta, Elizabeth D. Lightbody, Romanos Sklavenitis Pistofidis, Adam S. Sperling, Kenneth C. Anderson, Shonali Midha, Yuxin Liu, Jacob P. Laubach, Eric L. Smith, Nikhil C. Munshi, Omar Nadeem, Irene Ghobrial, Gad Getz
Journal: Blood
Blood (2024) 144 (Supplement 1): 492.
https://doi.org/10.1182/blood-2024-204132
Published: 2024
Journal Articles

Longitudinal Single-Cell Immune Profiling Reveals Distinct Dynamics of Response to Teclistamab in Patients with High-Risk Smoldering Myeloma Compared to Relapsed-Refractory Multiple Myeloma

Nayda Bidikian, Francesco Corrado, Romanos Sklavenitis-Pistofidis, Yoshinobu Konishi, Rosa Toenges, Jean-Baptiste Alberge, Michelle P. Aranha, Ting Wu, Michael Timonian, Shonali Midha, Elizabeth K. O'Donnell, Yuxin Liu, Sophie Magidson, Ashlee Strutevant, Kenneth C. Anderson, Nikhil C. Munshi, Omar Nadeem, Gad Getz, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 488.
https://doi.org/10.1182/blood-2024-207299
Published: 2024
Journal Articles

Moderate-Severe Thrombocytopenia Portends Poor Outcomes in Multiple Myeloma

Grace M. Ferri, Cenk Yildirim, Joseph Park, Nhan V. Do, Mary T. Brophy, Nikhil C. Munshi, Camille V. Edwards, Nathanael R. Fillmore
Journal: Blood
Blood (2024) 144 (Supplement 1): 6930.
https://doi.org/10.1182/blood-2024-206352
Published: 2024
Journal Articles

Development of Novel Peripheral Blood Count-Based Prognostic Index for Multiple Myeloma

Grace M. Ferri, Cenk Yildirim, Joseph Park, Nhan V. Do, Mary T. Brophy, Nikhil C. Munshi, Nathanael R. Fillmore, Camille V. Edwards
Journal: Blood
Blood (2024) 144 (Supplement 1): 6981.
https://doi.org/10.1182/blood-2024-206313
Published: 2024
Journal Articles

A Focused High Throughput Functional Screen Identifies Novel Targets for aggressive B-Cell Lymphoma

Chengcheng Liao, Sha He, Jie Sun, Qing Ke, Chao Rong, Baoping Guo, Xiaohong Tan, Srikanth Talluri, Masood A. Shammas, Nikhil C. Munshi, Hong Cen
Journal: Blood
Blood (2024) 144 (Supplement 1): 5758.
https://doi.org/10.1182/blood-2024-209515
Published: 2024
Journal Articles

A TCR-like CAR T Cell Therapy for the Treatment of MZB1 Positive Multiple Myeloma and Other B-Cell Malignancies

Elena Maroto Martin, Yingjie Zhao, Sara Mangesh Kolhatkar, Roberto Garcia-Vicente, Mubin Tarannum, Mehmet K. Samur, Mariateresa Fulciniti, Rizwan Romee, Jianzhu Chen, Nikhil C. Munshi
Journal: Blood
Blood (2024) 144 (Supplement 1): 4800.
https://doi.org/10.1182/blood-2024-208607
Published: 2024
Journal Articles

Phase II Trial of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone in High-Risk Smoldering Multiple Myeloma

Omar Nadeem, Sophie Magidson, Robert A. Redd, Jacob P. Laubach, Clifton C. Mo, Elizabeth K. O'Donnell, Adam S. Sperling, Monique A. Hartley-Brown, Shonali Midha, Yuxin Liu, Frances Arters, Marjorie Marto, Christine Davie, Caroline Ricciardi, Dechen Choden, Ashlee Strutevant, Jillian Alberti, Amy Goguen, Michael Constantine, Pedro Sanz-Altamira, Lorenzo Trippa, Nikhil C. Munshi, Kenneth C. Anderson, Paul G. Richardson, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 3360.
https://doi.org/10.1182/blood-2024-202653
Published: 2024
Journal Articles

A Novel Ribonuclease Targeting Small Molecule RNA-Degrader (MYC-RiboTAC) Overcomes MYC Dependency in Multiple Myeloma

Domenico Maisano, Tenghui Wang, Yuquan Tong, Vanessa Favasuli, Na Liu, Claire Gao, Chandraditya Chakraborty, Giulia Giorgetti, Francesco Ladisa, Marcello Turi, Francesca Barello, Michela Cumerlato, Anil Aktas-Samur, Mehmet K. Samur, Michael Cameron, Filip Garbicz, Ruben D. Carrasco, Mariateresa Fulciniti, Annamaria Gulla, Jessica Childs-Disney, Matthew D. Disney, Eugenio Morelli, Nikhil C. Munshi
Journal: Blood
Blood (2024) 144 (Supplement 1): 3268.
https://doi.org/10.1182/blood-2024-205528
Published: 2024
Journal Articles

Analysis of Alternative Splicing in Waldenstrom's Macroglobulinemia Reveals Novel Targets, Insights into IgM Production and Improved Gene Level Expression Estimates

Zachary R Hunter, Nickolas Tsakmaklis, Maria Luisa Guerrera, Amanda Kofides, Xia Liu, Shirong Liu, Abigail Peachey, Andres Felipe Ramirez Gamero, John M Hatcher, Catherine A. Flynn, Kirsten Meid, Christopher J Patterson, Mariateresa Fulciniti, Mehmet K. Samur, Kenneth C. Anderson, Nikhil C. Munshi, Shayna R Sarosiek, Jorge J. Castillo, Steven P. Treon
Journal: Blood
Blood (2024) 144 (Supplement 1): 2986.
https://doi.org/10.1182/blood-2024-212123
Published: 2024
Journal Articles

Bone Marrow Spatial Signatures Predict Survival Outcomes and Toxicities after CAR-T Therapy in Patients with Relapsed/Refractory Multiple Myeloma

Yoshinobu Konishi, David M. Cordas Dos Santos, Jacopo U. Verga, Patrick Costello, Sujal I. Shah, Qanber Raze, Liang S. Lim, Arnaldo G. Barican, David Howell, David King, Katherine Towle, Ruben D. Carrasco, Scott J. Rodig, Jon C. Aster, Adam S. Sperling, Eric L. Smith, Jacob Laubach, Nikhil C. Munshi, Kenneth C. Anderson, Omar Nadeem, Irene Ghobrial
Journal: Blood
Blood (2024) 144 (Supplement 1): 590.
https://doi.org/10.1182/blood-2024-204144
Published: 2024
Journal Articles

Synergistic Induction of Senescence-Driven Immune Responses and Myeloma Cell Cytotoxicity By CDK4/6 Inhibitors and Daratumumab Combination Therapy

Shiyi Xie, Zhen Yu, Mu Hao, Lu-Gui Qiu, Mariateresa Fulciniti, Nikhil C. Munshi, Yan Xu
Journal: Blood
Blood (2024) 144 (Supplement 1): 1410.
https://doi.org/10.1182/blood-2024-200479
Published: 2024
Journal Articles

Burden of Idiopathic Multicentric Castleman Disease (iMCD) in the US: A Population-Level Real World Analysis Using a Health-Claims Dataset

Ariela Noy, Robert Ohgami, Nikhil C. Munshi, Imran Siddiqi, Kelley C. Dacus, Alicia Watson Saltis, Francis Shupo, Nicole Princic, Kristin Evans, Sudipto Mukherjee
Journal: Blood
Blood (2024) 144 (Supplement 1): 797.
https://doi.org/10.1182/blood-2024-201745
Published: 2024