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Jens G. Lohr
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Journal Articles

Single-Cell RNA Sequencing of Circulating Myeloma Cells: Clinical Implications in Times of Immunotherapies

Joanna Blocka, Seong Gu Heo, Shonali Midha, Nathaniel G. Tadros, Steffen B. Kulp, Julia Frede, Marius Mathies, Nikhil C. Munshi, Andrew J. Yee, Jens G. Lohr
Journal: Blood
Blood (2024) 144 (Supplement 1): 1898.
https://doi.org/10.1182/blood-2024-198713
Published: 2024
Journal Articles

Genome-Wide CRISPR Screen Reveals IRF1 and TFAP4 As Transcriptional Regulators of Galectin-9 in T-Cell Acute Lymphoblastic Leukemia

Burak Yuzuguldu, Caroline R.M. Wiggers, Nathaniel G. Tadros, Eugene Y. Cho, Jens G. Lohr, Birgit Knoechel
Journal: Blood
Blood (2024) 144 (Supplement 1): 4223.
https://doi.org/10.1182/blood-2024-206403
Published: 2024
Journal Articles

Cellular Plasticity As Mechanisms to Escape from NOTCH1-Inhibition in T-ALL

Valeriya Dimitrova, Noori Sotudeh, Birgit Knoechel, Jens G. Lohr, Anna Montanaro, Sayalee V. Potdar, Julia Frede, Alexandria Van Scoyk, Shruti Bhatt, Praveen Anand, Jon C. Aster, David M Weinstock, Anthony G. Letai
Journal: Blood
Blood (2022) 140 (Supplement 1): 3461–3462.
https://doi.org/10.1182/blood-2022-170319
Published: 2022
Journal Articles

Nivolumab-Based Salvage Therapy to Restore T Cell Fitness in Penta-Refractory Multiple Myeloma with Relapse to Anti-BCMA CAR T Cell Therapy

Johannes M. Waldschmidt, Sankalp Arora, Tushara Vijaykumar, Noori Sotudeh, Praveen Anand, Hannah Stuart, Julia Frede, Tim Campbell, Shari M. Kaiser, Manisha Lamba, Nikhil C Munshi, Kenneth C. Anderson, Andrew J. Yee, Birgit Knoechel, Jens G. Lohr, Noopur Raje
Journal: Blood
Blood (2022) 140 (Supplement 1): 9925–9926.
https://doi.org/10.1182/blood-2022-168734
Published: 2022
Journal Articles

Single-Cell Multi-Omics Reveals Immune Microenvironment Alterations in T-Cell Acute Lymphoblastic Leukemia

Caroline R.M. Wiggers, Eugene Y. Cho, Justin Hegel, Julia Frede, Hannah Stuart, Klothilda K. Lim, Yana Pikman, Marian H. Harris, Andrew E. Place, Lewis B. Silverman, Jens G. Lohr, Birgit Knoechel
Journal: Blood
Blood (2022) 140 (Supplement 1): 9192–9193.
https://doi.org/10.1182/blood-2022-166511
Published: 2022
Journal Articles

Maturity State and MCL-1 Dependence Predetermines Response to NOTCH1 Inhibition in T-ALL

Valeriya Dimitrova, Noori Sotudeh, Anna Montanaro, Huiyoung Yun, Sayalee V. Potdar, Alexandria Van Scoyk, Shruti Bhatt, Praveen Anand, Antonis Kokkalis, Jake A. Kloeber, Julia Frede, Johannes M Waldschmidt, Anthony G. Letai, David M. Weinstock, Jens G. Lohr, Birgit Knoechel
Journal: Blood
Blood (2021) 138 (Supplement 1): 3484.
https://doi.org/10.1182/blood-2021-153829
Published: 2021
Journal Articles

Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL

Praveen Anand, Amy Guillaumet-Adkins, Valeriya Dimitrova, Huiyoung Yun, Yotam Drier, Noori Sotudeh, Anna Rogers, Madhu M. Ouseph, Monica Nair, Sayalee Potdar, Randi Isenhart, Jake A. Kloeber, Tushara Vijaykumar, Leili Niu, Tiffaney Vincent, Guangwu Guo, Julia Frede, Marian H. Harris, Andrew E. Place, Lewis B. Silverman, David T. Teachey, Andrew A. Lane, Daniel J. DeAngelo, Jon C. Aster, Bradley E. Bernstein, Jens G. Lohr, Birgit Knoechel
Journal: Blood
Blood (2021) 137 (18): 2463–2480.
https://doi.org/10.1182/blood.2019004547
Published: 2021
Includes: Supplemental data
Journal Articles

Determining Resistance Mechanisms in BRAF- mutated Multiple Myeloma

Johannes M. Waldschmidt, MD, Jake A. Kloeber, Tushara Vijaykumar, Antonis Kokkalis, PhD MSc, Praveen Anand, PhD, Sayalee Potdar, Julia Frede, PhD MPhil, Monica S. Nair, Valeriya Dimitrova, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD, Andrew J. Yee, MD, Noopur S. Raje, MD, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 316.
https://doi.org/10.1182/blood-2019-130313
Published: 2019
Journal Articles

Circulating Tumor DNA in the Peripheral Blood As Early Predictor of Clinical Outcome in Relapsed/ Refractory Multiple Myeloma

Johannes M. Waldschmidt, MD, Andrew J. Yee, MD, Tushara Vijaykumar, Julia Frede, PhD MPhil, Praveen Anand, PhD, Sayalee Potdar, Monica S. Nair, Antonis Kokkalis, PhD MSc, Jake A. Kloeber, Guangwu Guo, PhD, Samantha J. Shapiro, Mason L. Mann, Robb S Friedman, MD, Brea C. Lipe, MD, Erica L. Campagnaro, MD, Elizabeth K. O'Donnell, MD, Thomas Guerrero, MD, Jacob P. Laubach, MD, Nikhil C. Munshi, MD, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Noopur S. Raje, MD, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4350.
https://doi.org/10.1182/blood-2019-131037
Published: 2019
Journal Articles

Defining the Differentiation States of Multiple Myeloma at Single Cell Resolution Reveals Opportunities for Immunotherapy

Julia Frede, PhD MPhil, Praveen Anand, PhD, Andrew J. Yee, MD, Tushara Vijaykumar, Monica S. Nair, Johannes M. Waldschmidt, MD, Sayalee V. Potdar, Jake A. Kloeber, Antonis Kokkalis, PhD MSc, Guangwu Guo, PhD, Samantha J. Shapiro, Mason L. Mann, Robb S Friedman, MD, Brea C. Lipe, MD, Erica L. Campagnaro, MD, Craig E. Cole, MD, Elizabeth K. O'Donnell, MD, Thomas Guerrero, MD, Omar Nadeem, MD, Jacob P. Laubach, MD, Nikhil C. Munshi, MD, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Noopur Raje, MD, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3091.
https://doi.org/10.1182/blood-2019-130247
Published: 2019
Journal Articles

Single Cell RNA-Seq Reveals Deranged Developmental Hierarchy with Coexisting Oncogenic States and Immune Evasion Programs in ETP T-ALL

Amy Guillaumet-Adkins, PhD, Praveen Anand, PhD, Huiyoung Yun, PhD, Yotam Drier, PhD, Anna Rogers, Madhu M. Ouseph, Monica S. Nair, Sayalee Potdar, Randi Isenhart, Jake A. Kloeber, Tushara Vijaykumar, Guangwu Guo, Julia Frede, PhD MPhil, Marian H. Harris, MD PhD, Lewis B. Silverman, MD, Andrew A. Lane, MD PhD, Daniel J. DeAngelo, MD, Jon C. Aster, MD PhD, Bradley E. Bernstein, MD PhD, Jens G. Lohr, MD PhD, Birgit Knoechel, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3953.
https://doi.org/10.1182/blood-2019-130482
Published: 2019
Journal Articles

Enhancer Rewiring Dependent Switch from BCL2 to MCL1 Dependency Predicts NOTCH1 Inhibition Response in T-ALL

Valeriya Dimitrova, Huiyoung Yun, PhD, Sayalee Potdar, Alexandria Nicole Van Scoyk, BS, Shruti Bhatt, PhD, Praveen Anand, PhD, Monica S. Nair, Jake A. Kloeber, Antonis Kokkalis, PhD MSc, Julia Frede, PhD MPhil, Johannes M. Waldschmidt, MD, Anthony G. Letai, MD PhD, David M. Weinstock, MD, Jon C. Aster, MD PhD, Jens G. Lohr, MD PhD, Birgit Knoechel, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3948.
https://doi.org/10.1182/blood-2019-131148
Published: 2019
Journal Articles

Chromatin Structure Dynamics Preserve Genome Stability in Multiple Myeloma

Antonis Kokkalis, PhD MSc, Praveen Anand, PhD, Monica S. Nair, Johannes M. Waldschmidt, MD, Julia Frede, PhD MPhil, Tushara Vijaykumar, Amy Guillaumet-Adkins, PhD, Valeriya Dimitrova, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1777.
https://doi.org/10.1182/blood-2019-127495
Published: 2019
Journal Articles

A Phase II Study of Elotuzumab in Combination with Pomalidomide, Bortezomib, and Dexamethasone in Relapsed and Refractory Multiple Myeloma

Andrew J. Yee, MD, Jacob P. Laubach, MD, Erica L. Campagnaro, MD, Brea C. Lipe, MD, Omar Nadeem, MD, Robb S Friedman, MD, Craig E. Cole, MD, Elizabeth K. O'Donnell, MD, Giada Bianchi, MD, Andrew R. Branagan, MD, Samantha J. Shapiro, Cynthia C. Harrington, NP, Jill N. Burke, NP, Marilyn T. Gammon, RN, Kathleen J. Lively, RN, Cassandra A. Thorburn, Mason L. Mann, Jens G. Lohr, MD PhD, Kenneth C. Anderson, MD, Paul G. Richardson, MD, Noopur S. Raje, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3169.
https://doi.org/10.1182/blood-2019-124870
Published: 2019
Journal Articles

Genomic Discovery and Clonal Tracking in Multiple Myeloma By Cell Free DNA Sequencing

Guangwu Guo, PhD, Noopur Raje, MD, Charles M Seifer, Jake Kloeber, Randi Isenhart, Gavin Ha, PhD, Andrew J. Yee, MD, Elizabeth K. O'Donnell, MD, Yu-Tzu Tai, PhD, Jordan Voisine, Julia Frede, PhD, Antonis Kokkalis, PhD, Huiyoung Yun, PhD, Valeriya Dimitrova, PhD, Erica Gemme, Matthew Meyerson, MD PhD, Nikhil C Munshi, MD, Kenneth C. Anderson, MD, Birgit Knoechel, MDPhD, Jens G Lohr, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 329.
https://doi.org/10.1182/blood.V130.Suppl_1.329.329
Published: 2017
Journal Articles

Comprehensive Genetic Interrogation of Circulating Multiple Myeloma Cells at Single Cell Resolution

Jens G Lohr, MD PhD, Sora Kim, Joshua Gould, Birgit Knoechel, MD PhD, Yotam Drier, PhD, Daniel Gray, PhD, Nicole Birrer, Bang Wong, Gavin Ha, PhD, Cheng-Zhong Zhang, PhD, Guangwu Guo, Matthew Meyerson, MD PhD, Andrew Yee, Jesse Boehm, PhD, Noopur Raje, MD, Todd R. Golub, MD
Journal: Blood
Blood (2016) 128 (22): 800.
https://doi.org/10.1182/blood.V128.22.800.800
Published: 2016
Journal Articles

IL-2 Ameliorates Chronic GVHD by Inducing Antigen-Specific Regulatory T Cells.

Jens G. Lohr, MD, Birgit Knoechel, MD, Estelle C. Kahn, Abul K. Abbas, MD
Journal: Blood
Blood (2004) 104 (11): 2654.
https://doi.org/10.1182/blood.V104.11.2654.2654
Published: 2004
Journal Articles

Self-Reactivity in a Lymphopenic Mouse: A Model of Acute Graft-versus-Host Disease.

Birgit Knoechel, MD, Jens G. Lohr, MD, Estelle Kahn, Abul K. Abbas, MD
Journal: Blood
Blood (2004) 104 (11): 1341.
https://doi.org/10.1182/blood.V104.11.1341.1341
Published: 2004