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Journal Articles

Cellular Plasticity As Mechanisms to Escape from NOTCH1-Inhibition in T-ALL

Valeriya Dimitrova, Noori Sotudeh, Birgit Knoechel, Jens G. Lohr, Anna Montanaro, Sayalee V. Potdar, Julia Frede, Alexandria Van Scoyk, Shruti Bhatt, Praveen Anand, Jon C. Aster, David M Weinstock, Anthony G. Letai
Journal: Blood
Blood (2022) 140 (Supplement 1): 3461–3462.
https://doi.org/10.1182/blood-2022-170319
Published: 2022
Journal Articles

Nivolumab-Based Salvage Therapy to Restore T Cell Fitness in Penta-Refractory Multiple Myeloma with Relapse to Anti-BCMA CAR T Cell Therapy

Johannes M. Waldschmidt, Sankalp Arora, Tushara Vijaykumar, Noori Sotudeh, Praveen Anand, Hannah Stuart, Julia Frede, Tim Campbell, Shari M. Kaiser, Manisha Lamba, Nikhil C Munshi, Kenneth C. Anderson, Andrew J. Yee, Birgit Knoechel, Jens G. Lohr, Noopur Raje
Journal: Blood
Blood (2022) 140 (Supplement 1): 9925–9926.
https://doi.org/10.1182/blood-2022-168734
Published: 2022
Journal Articles

Maturity State and MCL-1 Dependence Predetermines Response to NOTCH1 Inhibition in T-ALL

Valeriya Dimitrova, Noori Sotudeh, Anna Montanaro, Huiyoung Yun, Sayalee V. Potdar, Alexandria Van Scoyk, Shruti Bhatt, Praveen Anand, Antonis Kokkalis, Jake A. Kloeber, Julia Frede, Johannes M Waldschmidt, Anthony G. Letai, David M. Weinstock, Jens G. Lohr, Birgit Knoechel
Journal: Blood
Blood (2021) 138 (Supplement 1): 3484.
https://doi.org/10.1182/blood-2021-153829
Published: 2021
Journal Articles

Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL

Praveen Anand, Amy Guillaumet-Adkins, Valeriya Dimitrova, Huiyoung Yun, Yotam Drier, Noori Sotudeh, Anna Rogers, Madhu M. Ouseph, Monica Nair, Sayalee Potdar, Randi Isenhart, Jake A. Kloeber, Tushara Vijaykumar, Leili Niu, Tiffaney Vincent, Guangwu Guo, Julia Frede, Marian H. Harris, Andrew E. Place, Lewis B. Silverman, David T. Teachey, Andrew A. Lane, Daniel J. DeAngelo, Jon C. Aster, Bradley E. Bernstein, Jens G. Lohr, Birgit Knoechel
Journal: Blood
Blood (2021) 137 (18): 2463–2480.
https://doi.org/10.1182/blood.2019004547
Published: 2021
Includes: Supplemental data
Journal Articles

Determining Resistance Mechanisms in BRAF- mutated Multiple Myeloma

Johannes M. Waldschmidt, MD, Jake A. Kloeber, Tushara Vijaykumar, Antonis Kokkalis, PhD MSc, Praveen Anand, PhD, Sayalee Potdar, Julia Frede, PhD MPhil, Monica S. Nair, Valeriya Dimitrova, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD, Andrew J. Yee, MD, Noopur S. Raje, MD, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 316.
https://doi.org/10.1182/blood-2019-130313
Published: 2019
Journal Articles

Circulating Tumor DNA in the Peripheral Blood As Early Predictor of Clinical Outcome in Relapsed/ Refractory Multiple Myeloma

Johannes M. Waldschmidt, MD, Andrew J. Yee, MD, Tushara Vijaykumar, Julia Frede, PhD MPhil, Praveen Anand, PhD, Sayalee Potdar, Monica S. Nair, Antonis Kokkalis, PhD MSc, Jake A. Kloeber, Guangwu Guo, PhD, Samantha J. Shapiro, Mason L. Mann, Robb S Friedman, MD, Brea C. Lipe, MD, Erica L. Campagnaro, MD, Elizabeth K. O'Donnell, MD, Thomas Guerrero, MD, Jacob P. Laubach, MD, Nikhil C. Munshi, MD, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Noopur S. Raje, MD, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4350.
https://doi.org/10.1182/blood-2019-131037
Published: 2019
Journal Articles

Defining the Differentiation States of Multiple Myeloma at Single Cell Resolution Reveals Opportunities for Immunotherapy

Julia Frede, PhD MPhil, Praveen Anand, PhD, Andrew J. Yee, MD, Tushara Vijaykumar, Monica S. Nair, Johannes M. Waldschmidt, MD, Sayalee V. Potdar, Jake A. Kloeber, Antonis Kokkalis, PhD MSc, Guangwu Guo, PhD, Samantha J. Shapiro, Mason L. Mann, Robb S Friedman, MD, Brea C. Lipe, MD, Erica L. Campagnaro, MD, Craig E. Cole, MD, Elizabeth K. O'Donnell, MD, Thomas Guerrero, MD, Omar Nadeem, MD, Jacob P. Laubach, MD, Nikhil C. Munshi, MD, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Noopur Raje, MD, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3091.
https://doi.org/10.1182/blood-2019-130247
Published: 2019
Journal Articles

Single Cell RNA-Seq Reveals Deranged Developmental Hierarchy with Coexisting Oncogenic States and Immune Evasion Programs in ETP T-ALL

Amy Guillaumet-Adkins, PhD, Praveen Anand, PhD, Huiyoung Yun, PhD, Yotam Drier, PhD, Anna Rogers, Madhu M. Ouseph, Monica S. Nair, Sayalee Potdar, Randi Isenhart, Jake A. Kloeber, Tushara Vijaykumar, Guangwu Guo, Julia Frede, PhD MPhil, Marian H. Harris, MD PhD, Lewis B. Silverman, MD, Andrew A. Lane, MD PhD, Daniel J. DeAngelo, MD, Jon C. Aster, MD PhD, Bradley E. Bernstein, MD PhD, Jens G. Lohr, MD PhD, Birgit Knoechel, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3953.
https://doi.org/10.1182/blood-2019-130482
Published: 2019
Journal Articles

Enhancer Rewiring Dependent Switch from BCL2 to MCL1 Dependency Predicts NOTCH1 Inhibition Response in T-ALL

Valeriya Dimitrova, Huiyoung Yun, PhD, Sayalee Potdar, Alexandria Nicole Van Scoyk, BS, Shruti Bhatt, PhD, Praveen Anand, PhD, Monica S. Nair, Jake A. Kloeber, Antonis Kokkalis, PhD MSc, Julia Frede, PhD MPhil, Johannes M. Waldschmidt, MD, Anthony G. Letai, MD PhD, David M. Weinstock, MD, Jon C. Aster, MD PhD, Jens G. Lohr, MD PhD, Birgit Knoechel, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3948.
https://doi.org/10.1182/blood-2019-131148
Published: 2019
Journal Articles

Chromatin Structure Dynamics Preserve Genome Stability in Multiple Myeloma

Antonis Kokkalis, PhD MSc, Praveen Anand, PhD, Monica S. Nair, Johannes M. Waldschmidt, MD, Julia Frede, PhD MPhil, Tushara Vijaykumar, Amy Guillaumet-Adkins, PhD, Valeriya Dimitrova, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1777.
https://doi.org/10.1182/blood-2019-127495
Published: 2019