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Journal Articles

Genome-Wide CRISPR Screen Reveals IRF1 and TFAP4 As Transcriptional Regulators of Galectin-9 in T-Cell Acute Lymphoblastic Leukemia

Burak Yuzuguldu, Caroline R.M. Wiggers, Nathaniel G. Tadros, Eugene Y. Cho, Jens G. Lohr, Birgit Knoechel

Blood (2024) 144 (Supplement 1): 4223.

https://doi.org/10.1182/blood-2024-206403

Published: 2024

Journal Articles

Combinatorial Effects of BH3 Mimetics and CAR T Cells Targeting T-Cell Lymphomas

Tayla B. Heavican-Foral, Felix Korell, Irene Scarfò, Harrison Silva, Allen Basanthakumar, Foster Powers, David M. Weinstock, Marcela V. Maus, Birgit Knoechel

Blood (2022) 140 (Supplement 1): 499–500.

https://doi.org/10.1182/blood-2022-159647

Published: 2022

Journal Articles

Single-Cell Multi-Omics Reveals Immune Microenvironment Alterations in T-Cell Acute Lymphoblastic Leukemia

Caroline R.M. Wiggers, Eugene Y. Cho, Justin Hegel, Julia Frede, Hannah Stuart, Klothilda K. Lim, Yana Pikman, Marian H. Harris, Andrew E. Place, Lewis B. Silverman, Jens G. Lohr, Birgit Knoechel

Blood (2022) 140 (Supplement 1): 9192–9193.

https://doi.org/10.1182/blood-2022-166511

Published: 2022

Journal Articles

Cellular Plasticity As Mechanisms to Escape from NOTCH1-Inhibition in T-ALL

Valeriya Dimitrova, Noori Sotudeh, Birgit Knoechel, Jens G. Lohr, Anna Montanaro, Sayalee V. Potdar, Julia Frede, Alexandria Van Scoyk, Shruti Bhatt, Praveen Anand, Jon C. Aster, David M Weinstock, Anthony G. Letai

Blood (2022) 140 (Supplement 1): 3461–3462.

https://doi.org/10.1182/blood-2022-170319

Published: 2022

Journal Articles

Nivolumab-Based Salvage Therapy to Restore T Cell Fitness in Penta-Refractory Multiple Myeloma with Relapse to Anti-BCMA CAR T Cell Therapy

Johannes M. Waldschmidt, Sankalp Arora, Tushara Vijaykumar, Noori Sotudeh, Praveen Anand, Hannah Stuart, Julia Frede, Tim Campbell, Shari M. Kaiser, Manisha Lamba, Nikhil C Munshi, Kenneth C. Anderson, Andrew J. Yee, Birgit Knoechel, Jens G. Lohr, Noopur Raje

Blood (2022) 140 (Supplement 1): 9925–9926.

https://doi.org/10.1182/blood-2022-168734

Published: 2022

Journal Articles

ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells

Blood (2022) 139 (3): 399–412.

https://doi.org/10.1182/blood.2020010405

Published: 2022

Includes: Supplemental data

Journal Articles

Maturity State and MCL-1 Dependence Predetermines Response to NOTCH1 Inhibition in T-ALL

Valeriya Dimitrova, Noori Sotudeh, Anna Montanaro, Huiyoung Yun, Sayalee V. Potdar, Alexandria Van Scoyk, Shruti Bhatt, Praveen Anand, Antonis Kokkalis, Jake A. Kloeber, Julia Frede, Johannes M Waldschmidt, Anthony G. Letai, David M. Weinstock, Jens G. Lohr, Birgit Knoechel

Blood (2021) 138 (Supplement 1): 3484.

https://doi.org/10.1182/blood-2021-153829

Published: 2021

Journal Articles

Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL

Blood (2021) 137 (18): 2463–2480.

https://doi.org/10.1182/blood.2019004547

Published: 2021

Includes: Supplemental data

Journal Articles

Chromatin Structure Dynamics Preserve Genome Stability in Multiple Myeloma

Antonis Kokkalis, PhD MSc, Praveen Anand, PhD, Monica S. Nair, Johannes M. Waldschmidt, MD, Julia Frede, PhD MPhil, Tushara Vijaykumar, Amy Guillaumet-Adkins, PhD, Valeriya Dimitrova, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD

Blood (2019) 134 (Supplement_1): 1777.

https://doi.org/10.1182/blood-2019-127495

Published: 2019

Journal Articles

Defining the Differentiation States of Multiple Myeloma at Single Cell Resolution Reveals Opportunities for Immunotherapy

Blood (2019) 134 (Supplement_1): 3091.

https://doi.org/10.1182/blood-2019-130247

Published: 2019

Journal Articles

Determining Resistance Mechanisms in BRAF- mutated Multiple Myeloma

Johannes M. Waldschmidt, MD, Jake A. Kloeber, Tushara Vijaykumar, Antonis Kokkalis, PhD MSc, Praveen Anand, PhD, Sayalee Potdar, Julia Frede, PhD MPhil, Monica S. Nair, Valeriya Dimitrova, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD, Andrew J. Yee, MD, Noopur S. Raje, MD, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD

Blood (2019) 134 (Supplement_1): 316.

https://doi.org/10.1182/blood-2019-130313

Published: 2019

Journal Articles

Single Cell RNA-Seq Reveals Deranged Developmental Hierarchy with Coexisting Oncogenic States and Immune Evasion Programs in ETP T-ALL

Blood (2019) 134 (Supplement_1): 3953.

https://doi.org/10.1182/blood-2019-130482

Published: 2019

Journal Articles

Enhancer Rewiring Dependent Switch from BCL2 to MCL1 Dependency Predicts NOTCH1 Inhibition Response in T-ALL

Valeriya Dimitrova, Huiyoung Yun, PhD, Sayalee Potdar, Alexandria Nicole Van Scoyk, BS, Shruti Bhatt, PhD, Praveen Anand, PhD, Monica S. Nair, Jake A. Kloeber, Antonis Kokkalis, PhD MSc, Julia Frede, PhD MPhil, Johannes M. Waldschmidt, MD, Anthony G. Letai, MD PhD, David M. Weinstock, MD, Jon C. Aster, MD PhD, Jens G. Lohr, MD PhD, Birgit Knoechel, MD PhD

Blood (2019) 134 (Supplement_1): 3948.

https://doi.org/10.1182/blood-2019-131148

Published: 2019

Journal Articles

Circulating Tumor DNA in the Peripheral Blood As Early Predictor of Clinical Outcome in Relapsed/ Refractory Multiple Myeloma

Blood (2019) 134 (Supplement_1): 4350.

https://doi.org/10.1182/blood-2019-131037

Published: 2019

Journal Articles

PRC2 Inactivation Induces Resistance to Chemotherapy-Induced Apoptosis By Upregulating the TRAP1 Mitochondrial Chaperone in T-ALL

Blood (2018) 132 (Supplement 1): 889.

https://doi.org/10.1182/blood-2018-99-113518

Published: 2018

Journal Articles

Identification of EHMT2 As a New Target in T-Cell Acute Lymphoblastic Leukemia

Samuel Kitara, Angela Su, Claudio Deluca, Franco Aversa, MD, Birgit Knoechel, MDPhD, Jian Jin, PhD, Kimberly Stegmaier, MD, Giovanni Roti, MD PhD

Blood (2017) 130 (Supplement 1): 2548.

https://doi.org/10.1182/blood.V130.Suppl_1.2548.2548

Published: 2017

Journal Articles

Genomic Discovery and Clonal Tracking in Multiple Myeloma By Cell Free DNA Sequencing

Blood (2017) 130 (Supplement 1): 329.

https://doi.org/10.1182/blood.V130.Suppl_1.329.329

Published: 2017

Journal Articles

PRC2 Mutations Induce Resistance to Conventional Chemotherapy By Inhibiting Mitochondrial Apoptosis in T-Cell Acute Lymphoblastic Leukemia

Blood (2016) 128 (22): 604.

https://doi.org/10.1182/blood.V128.22.604.604

Published: 2016

Journal Articles

Comprehensive Genetic Interrogation of Circulating Multiple Myeloma Cells at Single Cell Resolution

Jens G Lohr, MD PhD, Sora Kim, Joshua Gould, Birgit Knoechel, MD PhD, Yotam Drier, PhD, Daniel Gray, PhD, Nicole Birrer, Bang Wong, Gavin Ha, PhD, Cheng-Zhong Zhang, PhD, Guangwu Guo, Matthew Meyerson, MD PhD, Andrew Yee, Jesse Boehm, PhD, Noopur Raje, MD, Todd R. Golub, MD

Blood (2016) 128 (22): 800.

https://doi.org/10.1182/blood.V128.22.800.800

Published: 2016

Journal Articles

Peptidomimetic Blockade of MYB in Acute Myeloid Leukemia

Kavitha Ramaswamy, MD, Lauren Forbes, Fiona C Brown, PhD, Richard Koche, PhD, Tatyana Gindin, MDPhD, Gerard Minuesa, PhD, Michael G. Kharas, PhD, Andrei Krivtsov, PhD, Scott A. Armstrong, MD PhD, Eric Still, Elisa de Stanchina, PhD, Randi Isenhart, Guangwu Guo, Birgit Knoechel, MDPhD, Alex Kentsis, MD PhD

Blood (2016) 128 (22): 3945.

https://doi.org/10.1182/blood.V128.22.3945.3945

Published: 2016

NARROW

Genome-Wide CRISPR Screen Reveals IRF1 and TFAP4 As Transcriptional Regulators of Galectin-9 in T-Cell Acute Lymphoblastic Leukemia

Combinatorial Effects of BH3 Mimetics and CAR T Cells Targeting T-Cell Lymphomas

Single-Cell Multi-Omics Reveals Immune Microenvironment Alterations in T-Cell Acute Lymphoblastic Leukemia

Cellular Plasticity As Mechanisms to Escape from NOTCH1-Inhibition in T-ALL

Nivolumab-Based Salvage Therapy to Restore T Cell Fitness in Penta-Refractory Multiple Myeloma with Relapse to Anti-BCMA CAR T Cell Therapy

ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells

Maturity State and MCL-1 Dependence Predetermines Response to NOTCH1 Inhibition in T-ALL

Single-cell RNA-seq reveals developmental plasticity with coexisting oncogenic states and immune evasion programs in ETP-ALL

Chromatin Structure Dynamics Preserve Genome Stability in Multiple Myeloma

Defining the Differentiation States of Multiple Myeloma at Single Cell Resolution Reveals Opportunities for Immunotherapy

Determining Resistance Mechanisms in BRAF- mutated Multiple Myeloma

Single Cell RNA-Seq Reveals Deranged Developmental Hierarchy with Coexisting Oncogenic States and Immune Evasion Programs in ETP T-ALL

Enhancer Rewiring Dependent Switch from BCL2 to MCL1 Dependency Predicts NOTCH1 Inhibition Response in T-ALL

Circulating Tumor DNA in the Peripheral Blood As Early Predictor of Clinical Outcome in Relapsed/ Refractory Multiple Myeloma

PRC2 Inactivation Induces Resistance to Chemotherapy-Induced Apoptosis By Upregulating the TRAP1 Mitochondrial Chaperone in T-ALL

Identification of EHMT2 As a New Target in T-Cell Acute Lymphoblastic Leukemia

Genomic Discovery and Clonal Tracking in Multiple Myeloma By Cell Free DNA Sequencing

PRC2 Mutations Induce Resistance to Conventional Chemotherapy By Inhibiting Mitochondrial Apoptosis in T-Cell Acute Lymphoblastic Leukemia

Comprehensive Genetic Interrogation of Circulating Multiple Myeloma Cells at Single Cell Resolution

Peptidomimetic Blockade of MYB in Acute Myeloid Leukemia

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American Society of Hematology

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