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Journal Articles

BCMA bispecifics: breaking the chains of resistance

Johannes M. Waldschmidt, Leo Rasche

Blood (2024) 144 (25): 2566–2568.

https://doi.org/10.1182/blood.2024026932

Published: 2024

Journal Articles

Spatial transcriptomics reveals profound subclonal heterogeneity and T-cell dysfunction in extramedullary myeloma

Blood (2024) 144 (20): 2121–2135.

https://doi.org/10.1182/blood.2024024590

Published: 2024

Includes: Supplemental data

Journal Articles

Clinical and Diagnostic Challenges in Patients with Concomitant Plasma Cell Disorders and Myeloproliferative Neoplasms

Maximilian J Steinhardt, Thomas Bumm, Xiang Zhou, Umair Munawar, Seungbin Han, Julia Mersi, Hermann Einsele, Leo Rasche, K. Martin Kortüm, Johannes M Waldschmidt

Blood (2023) 142 (Supplement 1): 6771.

https://doi.org/10.1182/blood-2023-189528

Published: 2023

Journal Articles

Secondary Genetic Events Impact the Expression of Key Immunotargets on the Surface of Multiple Myeloma Cells

Umair Munawar, Patrick Eiring, Cornelia Vogt, Larissa Haertle, Seungbin Han, Silvia Nerreter, Eva Teufel, Max Steinhardt, Xiang Zhou, Santiago Barrio, Hermann Einsele, Johannes M Waldschmidt, Leo Rasche, Markus Sauer, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 451.

https://doi.org/10.1182/blood-2023-180638

Published: 2023

Journal Articles

Prolonged Cytopenia Following CAR T-Cell Therapy in Relapsed/Refractory Multiple Myeloma: A Prospective Comprehensive Biomarker Study

Xiang Zhou, Vivien Wagner, Emilia Stanojkovska, Christine Riedhammer, Xianghui Xiao, Mara John, Lukas Scheller, Umair Munawar, Seungbin Han, Johannes M Waldschmidt, Max S. Topp, Johannes Duell, Hermann Einsele, Angela Riedel, Martin Kortüm, Leo Rasche

Blood (2023) 142 (Supplement 1): 95.

https://doi.org/10.1182/blood-2023-180534

Published: 2023

Journal Articles

The Impact of Treatment-Free Intervals on T-Cell Exhaustion and Clonotypic Diversity in Myeloma Patients Treated with BCMA Bispecific Antibodies

Florian Eisele, Nazia Afrin, Emilia Stanojkovska, Mara John, Moutaz Helal, Lars Grundheber, Philipp Weis, Christine Riedhammer, Sofie-Katrin Kadel, Max Steinhardt, Johannes Duell, Johannes M Waldschmidt, Hermann Einsele, Angela Riedel, K. Martin Kortüm, Leo Rasche

Blood (2023) 142 (Supplement 1): 1938.

https://doi.org/10.1182/blood-2023-189042

Published: 2023

Journal Articles

Safety and Efficacy of Venetoclax Salvage Therapy in Relapsed/Refractory Multiple Myeloma with and without t(11;14)

Maximilian J Steinhardt, Max Bittrich, Xiang Zhou, Julia Noderer, Christine Riedhammer, Xianghui Xiao, Sophia Gawlas, Philipp Weis, Florian Eisele, Umair Munawar, Seungbin Han, Julia Mersi, Johannes M Waldschmidt, Hermann Einsele, Leo Rasche, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 6702.

https://doi.org/10.1182/blood-2023-189927

Published: 2023

Journal Articles

Taste Abnormalities Emerging during Anti-Myeloma Therapies Including GPRC5D x CD3 Bispecific Antibody Talquetamab

Anna Fleischer, Magdalena Roll, Franziska Panther, Goetz Gelbrich, Franziska Reinhardt, Christine Riedhammer, Julia Mersi, Johannes M Waldschmidt, Hermann Einsele, K. Martin Kortüm, Imad Maatouk, Leo Rasche

Blood (2023) 142 (Supplement 1): 2403.

https://doi.org/10.1182/blood-2023-186663

Published: 2023

Journal Articles

Functional Characterization of GPRC5D alteration and Its Impact on Talquetamab Resistance in Relapsed/ Refractory Multiple Myeloma

Seungbin Han, Umair Munawar, Larissa Haertle, Cornelia Vogt, Silvia Nerreter, Eva Teufel, Xiang Zhou, Max Steinhardt, Florian Eisele, Peter Raab, Marietta Truger, Sara Dorado, Santiago Barrio, Claudia Haferlach, Joaquin Martínez-López, Hermann Einsele, Leo Rasche, Johannes M Waldschmidt, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 3323.

https://doi.org/10.1182/blood-2023-181607

Published: 2023

Journal Articles

Euroflow-Based Ultrasensitive NGF for the Evaluation of Bone Marrow Minimal Residual Disease in Multiple Myeloma

Paula Tabares Gaviria, Katharina Schmiedgen, Jayabhuvaneshwari Dhanraj, Hüsniye Dagdeviren, Amy Wilnit, Maria Ulbrich, Bruno Paiva, K. Martin Kortüm, Leo Rasche, Hermann Einsele, Andreas Beilhack, Johannes M Waldschmidt

Blood (2023) 142 (Supplement 1): 3342.

https://doi.org/10.1182/blood-2023-189095

Published: 2023

Journal Articles

Differential CD38 Expression on Daratumumab-Naïve Vs. Resistant Multiple Myeloma - a Direct Stochastic Optical Reconstruction Microscopy ( d STORM) Analysis in 53 Patients

Maximilian J Steinhardt, Patrick Eiring, Cornelia Vogt, Umair Munawar, Seungbin Han, Larissa Haertle, Silvia Nerreter, Eva Teufel, Julia Mersi, Xiang Zhou, Michael Hudecek, Joaquin Martinez-Lopez, Johannes M Waldschmidt, Hermann Einsele, Leo Rasche, Markus Sauer, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 1992.

https://doi.org/10.1182/blood-2023-189741

Published: 2023

Journal Articles

Functional Imaging As a Key Diagnostic Tool in the Follow-up of RRMM Patients after CAR-T-Cell Therapy

Sven Schimanski, Hannah Hornburger, Sofie-Katrin Kadel, Anna Marie Ruckdeschel, Florian Eisele, Daniela Schneider, Anke Heidemeier, Andreas Buck, Rudolf Werner, Johannes M Waldschmidt, Paula Tabares, Andreas Beilhack, Johannes Duell, Hermann Einsele, K. Martin Kortüm, Max S. Topp, Leo Rasche

Blood (2023) 142 (Supplement 1): 3372.

https://doi.org/10.1182/blood-2023-188501

Published: 2023

Journal Articles

Bone Marrow Plasma Cell Infiltration Is a Prognostic Factor for Response to AL Amyloidosis Therapy

Maximilian J Steinhardt, Vladimir Cejka, Caroline Morbach, Aikaterini Papagianni, Silvia Nerreter, Cornelia Vogt, Umair Munawar, Seungbin Han, Leo Rasche, Johannes M Waldschmidt, Claudia Sommer, Stefan Störk, Hermann Einsele, K. Martin Kortüm

Blood (2023) 142 (Supplement 1): 6753.

https://doi.org/10.1182/blood-2023-189326

Published: 2023

Journal Articles

Nivolumab-Based Salvage Therapy to Restore T Cell Fitness in Penta-Refractory Multiple Myeloma with Relapse to Anti-BCMA CAR T Cell Therapy

Johannes M. Waldschmidt, Sankalp Arora, Tushara Vijaykumar, Noori Sotudeh, Praveen Anand, Hannah Stuart, Julia Frede, Tim Campbell, Shari M. Kaiser, Manisha Lamba, Nikhil C Munshi, Kenneth C. Anderson, Andrew J. Yee, Birgit Knoechel, Jens G. Lohr, Noopur Raje

Blood (2022) 140 (Supplement 1): 9925–9926.

https://doi.org/10.1182/blood-2022-168734

Published: 2022

Journal Articles

Maturity State and MCL-1 Dependence Predetermines Response to NOTCH1 Inhibition in T-ALL

Valeriya Dimitrova, Noori Sotudeh, Anna Montanaro, Huiyoung Yun, Sayalee V. Potdar, Alexandria Van Scoyk, Shruti Bhatt, Praveen Anand, Antonis Kokkalis, Jake A. Kloeber, Julia Frede, Johannes M Waldschmidt, Anthony G. Letai, David M. Weinstock, Jens G. Lohr, Birgit Knoechel

Blood (2021) 138 (Supplement 1): 3484.

https://doi.org/10.1182/blood-2021-153829

Published: 2021

Journal Articles

Determining Resistance Mechanisms in BRAF- mutated Multiple Myeloma

Johannes M. Waldschmidt, MD, Jake A. Kloeber, Tushara Vijaykumar, Antonis Kokkalis, PhD MSc, Praveen Anand, PhD, Sayalee Potdar, Julia Frede, PhD MPhil, Monica S. Nair, Valeriya Dimitrova, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD, Andrew J. Yee, MD, Noopur S. Raje, MD, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD

Blood (2019) 134 (Supplement_1): 316.

https://doi.org/10.1182/blood-2019-130313

Published: 2019

Journal Articles

Circulating Tumor DNA in the Peripheral Blood As Early Predictor of Clinical Outcome in Relapsed/ Refractory Multiple Myeloma

Blood (2019) 134 (Supplement_1): 4350.

https://doi.org/10.1182/blood-2019-131037

Published: 2019

Journal Articles

Defining the Differentiation States of Multiple Myeloma at Single Cell Resolution Reveals Opportunities for Immunotherapy

Blood (2019) 134 (Supplement_1): 3091.

https://doi.org/10.1182/blood-2019-130247

Published: 2019

Journal Articles

Enhancer Rewiring Dependent Switch from BCL2 to MCL1 Dependency Predicts NOTCH1 Inhibition Response in T-ALL

Valeriya Dimitrova, Huiyoung Yun, PhD, Sayalee Potdar, Alexandria Nicole Van Scoyk, BS, Shruti Bhatt, PhD, Praveen Anand, PhD, Monica S. Nair, Jake A. Kloeber, Antonis Kokkalis, PhD MSc, Julia Frede, PhD MPhil, Johannes M. Waldschmidt, MD, Anthony G. Letai, MD PhD, David M. Weinstock, MD, Jon C. Aster, MD PhD, Jens G. Lohr, MD PhD, Birgit Knoechel, MD PhD

Blood (2019) 134 (Supplement_1): 3948.

https://doi.org/10.1182/blood-2019-131148

Published: 2019

Journal Articles

Chromatin Structure Dynamics Preserve Genome Stability in Multiple Myeloma

Antonis Kokkalis, PhD MSc, Praveen Anand, PhD, Monica S. Nair, Johannes M. Waldschmidt, MD, Julia Frede, PhD MPhil, Tushara Vijaykumar, Amy Guillaumet-Adkins, PhD, Valeriya Dimitrova, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD

Blood (2019) 134 (Supplement_1): 1777.

https://doi.org/10.1182/blood-2019-127495

Published: 2019

NARROW

BCMA bispecifics: breaking the chains of resistance

Spatial transcriptomics reveals profound subclonal heterogeneity and T-cell dysfunction in extramedullary myeloma

Clinical and Diagnostic Challenges in Patients with Concomitant Plasma Cell Disorders and Myeloproliferative Neoplasms

Secondary Genetic Events Impact the Expression of Key Immunotargets on the Surface of Multiple Myeloma Cells

Prolonged Cytopenia Following CAR T-Cell Therapy in Relapsed/Refractory Multiple Myeloma: A Prospective Comprehensive Biomarker Study

The Impact of Treatment-Free Intervals on T-Cell Exhaustion and Clonotypic Diversity in Myeloma Patients Treated with BCMA Bispecific Antibodies

Safety and Efficacy of Venetoclax Salvage Therapy in Relapsed/Refractory Multiple Myeloma with and without t(11;14)

Taste Abnormalities Emerging during Anti-Myeloma Therapies Including GPRC5D x CD3 Bispecific Antibody Talquetamab

Functional Characterization of GPRC5D alteration and Its Impact on Talquetamab Resistance in Relapsed/ Refractory Multiple Myeloma

Euroflow-Based Ultrasensitive NGF for the Evaluation of Bone Marrow Minimal Residual Disease in Multiple Myeloma

Differential CD38 Expression on Daratumumab-Naïve Vs. Resistant Multiple Myeloma - a Direct Stochastic Optical Reconstruction Microscopy ( d STORM) Analysis in 53 Patients

Functional Imaging As a Key Diagnostic Tool in the Follow-up of RRMM Patients after CAR-T-Cell Therapy

Bone Marrow Plasma Cell Infiltration Is a Prognostic Factor for Response to AL Amyloidosis Therapy

Nivolumab-Based Salvage Therapy to Restore T Cell Fitness in Penta-Refractory Multiple Myeloma with Relapse to Anti-BCMA CAR T Cell Therapy

Maturity State and MCL-1 Dependence Predetermines Response to NOTCH1 Inhibition in T-ALL

Determining Resistance Mechanisms in BRAF- mutated Multiple Myeloma

Circulating Tumor DNA in the Peripheral Blood As Early Predictor of Clinical Outcome in Relapsed/ Refractory Multiple Myeloma

Defining the Differentiation States of Multiple Myeloma at Single Cell Resolution Reveals Opportunities for Immunotherapy

Enhancer Rewiring Dependent Switch from BCL2 to MCL1 Dependency Predicts NOTCH1 Inhibition Response in T-ALL

Chromatin Structure Dynamics Preserve Genome Stability in Multiple Myeloma

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American Society of Hematology

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American Society of Hematology

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