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Judith S. Hecker
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Journal Articles

Pre-Apheresis Prediction of Toxicity and Response in Patients Receiving BCMA-Directed CAR-T for Relapsed/Refractory Multiple Myeloma

Kai Rejeski, Doris K. Hansen, David M. Cordas Dos Santos, Andre De Menezes Silva Corraes, Omar Castaneda, Christen M Dillard, Winfried Alsdorf, Jan H. Frenking, Anna Purcarea, Saurabh Chhabra, Ciara Louise Freeman, Mirco Julian Friedrich, Mahmoud R. Gaballa, Rebecca Gonzalez, Syed Hamza Bin Waqar, Yi Lisa Hwa, Michael D. Jain, Ricardo D. Parrondo, Oren Pasvolsky, Wajma Shahbaz, Roni Shouval, Genevieve Spiess, Haily Stephens, Sebastian Theurich, Florian Bassermann, Judith S. Hecker, Marc S. Raab, Katja C. Weisel, Frederick L. Locke, Marion Subklewe, Krina K. Patel, Yi Lin
Journal: Blood
Blood (2024) 144 (Supplement 1): 895.
https://doi.org/10.1182/blood-2024-208376
Published: 2024
Journal Articles

IDH2 Mutations from Clonal Hematopoiesis and Acquired IKZF1 Deletions Define a Novel B-ALL Subtype after Lenalidomide Therapy for Multiple Myeloma

Johanna Maria Horns, Thomas Beder, Malwine J Barz, Aeint-Steffen Ströh, Axel Künstner, Sonja Bendig, Guranda Chitadze, Cecilia Bozzetti, Nikos Darzentas, Katharina Iben, Michaela Kotrova, Martin Neumann, Wiebke Weßels, Hauke Busch, Lennart Lenk, Judith S. Hecker, Stefan Knop, Boris Böll, Johannes Duell, Walter Fiedler, Christoph Faul, Christoph Röllig, Bernd Spriewald, Björn Steffen, Maher Hanoun, Nicola Goekbuget, Claudia D Baldus, Lorenz Bastian, Monika Brüggemann
Journal: Blood
Blood (2024) 144 (Supplement 1): 631.
https://doi.org/10.1182/blood-2024-199601
Published: 2024
Journal Articles

Prevalence and Mutational Make-up of Secondary Hematologic Neoplasms in Multiple Myeloma Patients after CAR-T Cell Therapy

Johannes Waldschmidt, Maximilian Merz, Judith S. Hecker, Franz Reinhard, Benjamin GT Shibru, Marion Hoegner, Anna Gebauer, David Fandrei, Manja Meggendorfer, Marietta Truger, Johannes Jung, Daniel Teschner, Max S. Topp, Anna Purcarea, Vladan Vucinic, Martin K. Kortüm, Torsten Haferlach, Florian Bassermann, Uwe Platzbecker, Hermann Einsele, Claudia Haferlach, Klaus H Metzeler, Katharina S. S. Götze, Leo Rasche
Journal: Blood
Blood (2024) 144 (Supplement 1): 4688.
https://doi.org/10.1182/blood-2024-210233
Published: 2024
Journal Articles

Single Cell Multiomic Analysis of Bone Marrow Hematopoietic Stem/Progenitor Cells from Individuals with Clonal Hematopoiesis Reveals Potential Mechanisms of Anemia Development

Michele C Buck, Jennifer Rivière, Anna Navarro Figueredo, Daniele Scarcella, Maximilian Buser, Judith S. Hecker, Mark van der Garde, Carsten Marr, Katharina S. Götze
Journal: Blood
Blood (2024) 144 (Supplement 1): 2666.
https://doi.org/10.1182/blood-2024-211093
Published: 2024
Journal Articles

Single-Cell Transcriptomics of Bone Marrow Mesenchymal Stromal Cells Identifies Altered CLCF1 Signaling in DNMT3A -Mutated Clonal Hematopoiesis

Anna Navarro Figueredo, Daniele Scarcella, Michele C Buck, Maximilian Buser, Jennifer Rivière, Michael Sterr, Wencke Walter, Priyansh Srivastava, Judith S. Hecker, Ana Conesa, Mark van der Garde, Carsten Marr, Katharina S. Götze
Journal: Blood
Blood (2024) 144 (Supplement 1): 2676.
https://doi.org/10.1182/blood-2024-210254
Published: 2024
Journal Articles

Mesenchymal Stromal Cells from Individuals with DNMT3A mut Clonal Hematopoiesis Instruct Young Healthy Hematopoietic Stem/Progenitor Cells Towards a Myeloid-Biased Aging Phenotype Resembling That of Patients with Clonal Cytopenia of Undetermined Significance (CCUS)

Anna Navarro Figueredo, Wencke Walter, Jennifer Rivière, Marit Leilich, Siddhi Pawar, Michèle Buck, Judith S. Hecker, Marta Benegas Coll, Carolina Monzó, Maki Sakuma, Priyansh Srivastava, Ana Conesa, Torsten Haferlach, Mark Van Der Garde, Katharina S. Götze
Journal: Blood
Blood (2023) 142 (Supplement 1): 2703.
https://doi.org/10.1182/blood-2023-188781
Published: 2023
Journal Articles

Targeting FLT3 with a new-generation antibody-drug conjugate in combination with kinase inhibitors for treatment of AML

Maike Roas, Binje Vick, Marc-André Kasper, Marina Able, Harald Polzer, Marcus Gerlach, Elisabeth Kremmer, Judith S. Hecker, Saskia Schmitt, Andreas Stengl, Verena Waller, Natascha Hohmann, Moreno Festini, Alexander Ludwig, Lisa Rohrbacher, Tobias Herold, Marion Subklewe, Katharina S. Götze, Christian P. R. Hackenberger, Dominik Schumacher, Jonas Helma-Smets, Irmela Jeremias, Heinrich Leonhardt, Karsten Spiekermann
Journal: Blood
Blood (2023) 141 (9): 1023–1035.
https://doi.org/10.1182/blood.2021015246
Published: 2023
Includes: Supplemental data
Journal Articles

Single Cell Transcriptomic Analysis of the Bone Marrow Microenvironment Uncovers a Role for Antigen Presentation Processes in MDS/AML Relapse after Allogeneic Hematopoietic Stem Cell Transplantation

Jennifer Rivière, Mark van der Garde, Judith S. Hecker, Michèle C. Buck, Florian Bassermann, Mareike Verbeek, Katharina S. Goetze
Journal: Blood
Blood (2022) 140 (Supplement 1): 2906–2907.
https://doi.org/10.1182/blood-2022-165255
Published: 2022
Journal Articles

Targeting Extracellular Vesicle Secretion in Combination with Venetoclax Synergistically Induces Apoptosis in FLT3-ITD+ AML

Judith S. Hecker, Jennifer Rivière, Mark van der Garde, Michèle C. Buck, Rupert Öllinger, Florian Bassermann, Bernd Giebel, Robert A.J. Oostendorp, Roland Rad, Katharina S. Goetze
Journal: Blood
Blood (2022) 140 (Supplement 1): 8711–8712.
https://doi.org/10.1182/blood-2022-169065
Published: 2022
Journal Articles

Autophagy in mesenchymal progenitors protects mice against bone marrow failure after severe intermittent stress

Theresa Landspersky, Mehmet Saçma, Jennifer Rivière, Judith S. Hecker, Franziska Hettler, Erik Hameister, Katharina Brandstetter, Rouzanna Istvánffy, Sandra Romero Marquez, Romina Ludwig, Marilena Götz, Michèle Buck, Martin Wolf, Matthias Schiemann, Jürgen Ruland, Dirk Strunk, Akiko Shimamura, Kasiani Myers, Terry P. Yamaguchi, Matthias Kieslinger, Heinrich Leonhardt, Florian Bassermann, Katharina S. Götze, Hartmut Geiger, Christina Schreck, Robert A. J. Oostendorp
Journal: Blood
Blood (2022) 139 (5): 690–703.
https://doi.org/10.1182/blood.2021011775
Published: 2022
Includes: Supplemental data
Journal Articles

Characterization of Somatic Mosaicism and Mutational Profiling of Clonal Hematopoiesis Compared to MDS and sAML Depicts Diversities of Clonal Evolution

Judith S. Hecker, Luise Hartmann, Maja Rothenberg-Thurley, Jennifer Rivière, Bianka Ksienzyk, Michele C. Buck, Mark Van Der Garde, Luise Fischer, Susann Winter, Martina Rauner, Elena Tsourdi, Katja Sockel, Marie Schneider, Anne Sophie Kubasch, Martin Nolde, Dominikus Hausmann, Jörg Lützner, Andreas Roth, Florian Bassermann, Karsten Spiekermann, Lorenz Hofbauer, Uwe Platzbecker, Klaus H. Metzeler, Katharina S. Goetze
Journal: Blood
Blood (2021) 138 (Supplement 1): 3278.
https://doi.org/10.1182/blood-2021-152187
Published: 2021
Journal Articles

CHIP and hips: clonal hematopoiesis is common in patients undergoing hip arthroplasty and is associated with autoimmune disease

Brief Report
Judith S. Hecker, Luise Hartmann, Jennifer Rivière, Michèle C. Buck, Mark van der Garde, Maja Rothenberg-Thurley, Luise Fischer, Susann Winter, Bianka Ksienzyk, Frank Ziemann, Maria Solovey, Martina Rauner, Elena Tsourdi, Katja Sockel, Marie Schneider, Anne S. Kubasch, Martin Nolde, Dominikus Hausmann, Alexander C. Paulus, Jörg Lützner, Andreas Roth, Florian Bassermann, Karsten Spiekermann, Carsten Marr, Lorenz C. Hofbauer, Uwe Platzbecker, Klaus H. Metzeler, Katharina S. Götze
Journal: Blood
Blood (2021) 138 (18): 1727–1732.
https://doi.org/10.1182/blood.2020010163
Published: 2021
Includes: Supplemental data