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Mark van der Garde
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Journal Articles

Single Cell Multiomic Analysis of Bone Marrow Hematopoietic Stem/Progenitor Cells from Individuals with Clonal Hematopoiesis Reveals Potential Mechanisms of Anemia Development

Michele C Buck, Jennifer Rivière, Anna Navarro Figueredo, Daniele Scarcella, Maximilian Buser, Judith S. Hecker, Mark van der Garde, Carsten Marr, Katharina S. Götze
Journal: Blood
Blood (2024) 144 (Supplement 1): 2666.
https://doi.org/10.1182/blood-2024-211093
Published: 2024
Journal Articles

Single-Cell Transcriptomics of Bone Marrow Mesenchymal Stromal Cells Identifies Altered CLCF1 Signaling in DNMT3A -Mutated Clonal Hematopoiesis

Anna Navarro Figueredo, Daniele Scarcella, Michele C Buck, Maximilian Buser, Jennifer Rivière, Michael Sterr, Wencke Walter, Priyansh Srivastava, Judith S. Hecker, Ana Conesa, Mark van der Garde, Carsten Marr, Katharina S. Götze
Journal: Blood
Blood (2024) 144 (Supplement 1): 2676.
https://doi.org/10.1182/blood-2024-210254
Published: 2024
Journal Articles

Mesenchymal Stromal Cells from Individuals with DNMT3A mut Clonal Hematopoiesis Instruct Young Healthy Hematopoietic Stem/Progenitor Cells Towards a Myeloid-Biased Aging Phenotype Resembling That of Patients with Clonal Cytopenia of Undetermined Significance (CCUS)

Anna Navarro Figueredo, Wencke Walter, Jennifer Rivière, Marit Leilich, Siddhi Pawar, Michèle Buck, Judith S. Hecker, Marta Benegas Coll, Carolina Monzó, Maki Sakuma, Priyansh Srivastava, Ana Conesa, Torsten Haferlach, Mark Van Der Garde, Katharina S. Götze
Journal: Blood
Blood (2023) 142 (Supplement 1): 2703.
https://doi.org/10.1182/blood-2023-188781
Published: 2023
Journal Articles

Single Cell Transcriptomic Analysis of the Bone Marrow Microenvironment Uncovers a Role for Antigen Presentation Processes in MDS/AML Relapse after Allogeneic Hematopoietic Stem Cell Transplantation

Jennifer Rivière, Mark van der Garde, Judith S. Hecker, Michèle C. Buck, Florian Bassermann, Mareike Verbeek, Katharina S. Goetze
Journal: Blood
Blood (2022) 140 (Supplement 1): 2906–2907.
https://doi.org/10.1182/blood-2022-165255
Published: 2022
Journal Articles

Targeting Extracellular Vesicle Secretion in Combination with Venetoclax Synergistically Induces Apoptosis in FLT3-ITD+ AML

Judith S. Hecker, Jennifer Rivière, Mark van der Garde, Michèle C. Buck, Rupert Öllinger, Florian Bassermann, Bernd Giebel, Robert A.J. Oostendorp, Roland Rad, Katharina S. Goetze
Journal: Blood
Blood (2022) 140 (Supplement 1): 8711–8712.
https://doi.org/10.1182/blood-2022-169065
Published: 2022
Journal Articles

Characterization of Somatic Mosaicism and Mutational Profiling of Clonal Hematopoiesis Compared to MDS and sAML Depicts Diversities of Clonal Evolution

Judith S. Hecker, Luise Hartmann, Maja Rothenberg-Thurley, Jennifer Rivière, Bianka Ksienzyk, Michele C. Buck, Mark Van Der Garde, Luise Fischer, Susann Winter, Martina Rauner, Elena Tsourdi, Katja Sockel, Marie Schneider, Anne Sophie Kubasch, Martin Nolde, Dominikus Hausmann, Jörg Lützner, Andreas Roth, Florian Bassermann, Karsten Spiekermann, Lorenz Hofbauer, Uwe Platzbecker, Klaus H. Metzeler, Katharina S. Goetze
Journal: Blood
Blood (2021) 138 (Supplement 1): 3278.
https://doi.org/10.1182/blood-2021-152187
Published: 2021
Journal Articles

CHIP and hips: clonal hematopoiesis is common in patients undergoing hip arthroplasty and is associated with autoimmune disease

Brief Report
Judith S. Hecker, Luise Hartmann, Jennifer Rivière, Michèle C. Buck, Mark van der Garde, Maja Rothenberg-Thurley, Luise Fischer, Susann Winter, Bianka Ksienzyk, Frank Ziemann, Maria Solovey, Martina Rauner, Elena Tsourdi, Katja Sockel, Marie Schneider, Anne S. Kubasch, Martin Nolde, Dominikus Hausmann, Alexander C. Paulus, Jörg Lützner, Andreas Roth, Florian Bassermann, Karsten Spiekermann, Carsten Marr, Lorenz C. Hofbauer, Uwe Platzbecker, Klaus H. Metzeler, Katharina S. Götze
Journal: Blood
Blood (2021) 138 (18): 1727–1732.
https://doi.org/10.1182/blood.2020010163
Published: 2021
Includes: Supplemental data
Journal Articles

CD244 Marks Non-Functional Hematopoietic Stem Cells with a Mast Cell Signature after Induction of Endoplasmic Reticulum Stress

Valgardur Sigurdsson, PhD, Shuhei Koide, PhD, Visnja Radulovic, PhD, Els Mansell, PhD, Mark Van Der Garde, MSc, PhD, Tiit Örd, PhD, Tonis Örd, PhD, Kenichi Miharada, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2474.
https://doi.org/10.1182/blood-2019-128239
Published: 2019
Journal Articles

A Transient Induction of Blood-Circulating Bile Acid Is a Therapeutic Marker and Target of Chemotherapy-Oriented Myelosuppression

Valgardur Sigurdsson, PhD, Youichi Haga, MD PhD, Hajime Takei, PhD, Chizuko Okamatsu-Haga, MD PhD, Visnja Radulovic, PhD, Mark Van Der Garde, PhD, Mitsuyoshi Suzuki, MD PhD, Svetlana Soboleva, Hiroshi Nittono, MD PhD, Akira Ohara, MD, Kenichi Miharada, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3344.
https://doi.org/10.1182/blood.V130.Suppl_1.3344.3344
Published: 2017
Journal Articles

Junctional Adhesion Molecule 2 Intensifies T Lymphopoiesis of Hematopoietic Stem Cells By Facilitating Notch/Delta Signaling

Visnja Radulovic, PhD, Mark Van Der Garde, PhD, Valgardur Sigurdsson, PhD, Alya Zriwil, PhD, Svetlana Soboleva, Ewa Sitnicka Quinn, PhD, Shin Kaneko, MD PhD, Kenichi Miharada, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 635.
https://doi.org/10.1182/blood.V130.Suppl_1.635.635
Published: 2017
Journal Articles

Molecular Insights at the Single Cell Level into the Reprogramming of Human Hematopoietic Stem Cells during Epigenetically Modified Ex Vivo Expansion

Peng Hua, PhD, Barbara Kronsteiner, PhD, Neil Ashley, PhD, Mark van der Garde, PhD, Diana Hernandez, PhD, Marina Tarunina, PhD, Lilian Hook, PhD, Yen Choo, PhD, Irene Roberts, MD, Adam J Mead, MD PhD, Suzanne M Watt, PhDFRCPath
Journal: Blood
Blood (2017) 130 (Supplement 1): 2425.
https://doi.org/10.1182/blood.V130.Suppl_1.2425.2425
Published: 2017
Journal Articles

Expansion and Biased Commitment of Hematopoietic Stem Cells Towards Erythroid Cells upon Acute Anemia Induction

Mark van der Garde, PhD, Valgardur Sigurdsson, PhD, Visnja Radulovic, PhD, Svetlana Soboleva, Abdul Ghani Alattar, Kenichi Miharada, PhD
Journal: Blood
Blood (2016) 128 (22): 1270.
https://doi.org/10.1182/blood.V128.22.1270.1270
Published: 2016
Journal Articles

Junctional Adhesion Molecule 2 Represents a Novel Subset of Hematopoietic Stem Cells Poised for T Lymphopoiesis

Visnja Radulovic, PhD, Mark van der Garde, PhD, Valgardur Sigurdsson, PhD, Alya Zriwil, Svetlana Soboleva, Shin Kaneko, MD PhD, Ewa Sitnicka Quinn, PhD, Kenichi Miharada, PhD
Journal: Blood
Blood (2016) 128 (22): 3862.
https://doi.org/10.1182/blood.V128.22.3862.3862
Published: 2016
Journal Articles

Direct Comparison of Wharton Jelly and Bone Marrow Derived Mesenchymal Stromal Cells to Enhance Engraftment of Cord Blood CD34 + Transplants

Mark van der Garde, Melissa Van Pel, PhD, Jose Millan Rivero, Alice de Graaf-Dijkstra, Manon Slot, Yoshiko Kleinveld, Suzanne Watt, PhDFRCPath, Helene Roelofs, PhD, Jaap Jan Zwaginga, MD PhD
Journal: Blood
Blood (2015) 126 (23): 5410.
https://doi.org/10.1182/blood.V126.23.5410.5410
Published: 2015