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Angela Riedel
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Journal Articles

Increased teclistamab dosing interval improves T-cell diversity and reduces infection risk, while T-cell exhaustion remains minimal irrespective of schedule

Free
Nazia Afrin, Florian Eisele, Emilia Stanojkovska, Mara John, Hanna Fischer, Moutaz Helal, Carolin Köchel, Niklas Kehl, Lars Grundheber, Philipp Weis, Christine Riedhammer, Sofie-Katrin Kadel, Julia Mersi, Torsten Steinbrunn, Johannes Waldschmidt, Sabrina Kraus, Johannes Duell, K. Martin Kortüm, Mirco Friedrich, Hermann Einsele, Angela Riedel, Leo Rasche
Journal: Blood
Blood (2025) 146 (Supplement 1): 802.
https://doi.org/10.1182/blood-2025-802
Published: 2025
Journal Articles

An acquired immune-metabolic shift to common chemotherapy confers resistance to immunotherapies in relapsed, high-risk multiple myeloma

Free
Mara John, Nazia Afrin, Emilia Stanojkovska, Hanna Fischer, Maximilian Krämer, Werner Schmitz, Lars Grundheber, Moutaz Helal, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Xiang Zhou, Max Steinhardt, Benedict Engel, Anni Hofmann, Julia Mersi, Johannes Waldschmidt, Hermann Einsele, K. Martin Kortüm, Leo Rasche, Angela Riedel
Journal: Blood
Blood (2025) 146 (Supplement 1): 3938.
https://doi.org/10.1182/blood-2025-3938
Published: 2025
Journal Articles

Spatial transcriptomics reveals profound subclonal heterogeneity and T-cell dysfunction in extramedullary myeloma

Free
Mara John, Moutaz Helal, Johannes Duell, Greta Mattavelli, Emilia Stanojkovska, Nazia Afrin, Alexander M. Leipold, Maximilian J. Steinhardt, Xiang Zhou, David Žihala, Anjana Anilkumar Sithara, Julia Mersi, Johannes M. Waldschmidt, Christine Riedhammer, Sofie-Katrin Kadel, Marietta Truger, Rudolf A. Werner, Claudia Haferlach, Hermann Einsele, Kai Kretzschmar, Tomáš Jelínek, Andreas Rosenwald, K. Martin Kortüm, Angela Riedel, Leo Rasche
Journal: Blood
Blood (2024) 144 (20): 2121–2135.
https://doi.org/10.1182/blood.2024024590
Published: 2024
Includes: Supplemental data
Journal Articles

Classic Anti-Myeloma Treatments Alter Circulating Immune Cell Subsets with Potential Implications for T Cell Immunotherapies in Multiple Myeloma

Free
Xiang Zhou, Sarah Wiethe, Angelika Wolff, Max J Steinhardt, Nazia Afrin, Mara John, Christine Riedhammer, Xianghui Xiao, Umair Munawar, Julia Mersi, Seungbin Han, Johannes Waldschmidt, Angela Riedel, Max S. Topp, Johannes Duell, Hermann Einsele, K. Martin Kortüm, Leo Rasche
Journal: Blood
Blood (2024) 144 (Supplement 1): 4705.
https://doi.org/10.1182/blood-2024-203391
Published: 2024
Journal Articles

The Impact of Treatment-Free Intervals on T-Cell Exhaustion and Clonotypic Diversity in Myeloma Patients Treated with BCMA Bispecific Antibodies

Free
Florian Eisele, Nazia Afrin, Emilia Stanojkovska, Mara John, Moutaz Helal, Lars Grundheber, Philipp Weis, Christine Riedhammer, Sofie-Katrin Kadel, Max Steinhardt, Johannes Duell, Johannes M Waldschmidt, Hermann Einsele, Angela Riedel, K. Martin Kortüm, Leo Rasche
Journal: Blood
Blood (2023) 142 (Supplement 1): 1938.
https://doi.org/10.1182/blood-2023-189042
Published: 2023
Journal Articles

Prolonged Cytopenia Following CAR T-Cell Therapy in Relapsed/Refractory Multiple Myeloma: A Prospective Comprehensive Biomarker Study

Free
Xiang Zhou, Vivien Wagner, Emilia Stanojkovska, Christine Riedhammer, Xianghui Xiao, Mara John, Lukas Scheller, Umair Munawar, Seungbin Han, Johannes M Waldschmidt, Max S. Topp, Johannes Duell, Hermann Einsele, Angela Riedel, Martin Kortüm, Leo Rasche
Journal: Blood
Blood (2023) 142 (Supplement 1): 95.
https://doi.org/10.1182/blood-2023-180534
Published: 2023
Journal Articles

The T-Cell Metabolic Phenotype Is Dependent on Risk Status and Degree of PC Bone Marrow Infiltration in Multiple Myeloma

Free
Mara John, Moutaz Helal, Lars Grundheber, Greta Mattavelli, Nazia Afrin, Xiang Zhou, Benedict Engel, Werner Schmitz, Emilia Stanojkovska, Cornelia Vogt, Silvia Nerreter, Eva Teufel, Julia Mersi, Hermann Einsele, K. Martin Kortuem, Angela Riedel, Leo Rasche
Journal: Blood
Blood (2022) 140 (Supplement 1): 9959–9960.
https://doi.org/10.1182/blood-2022-168608
Published: 2022
Journal Articles

Spatial Transcriptomics Reveals a Multi Cellular Ecosystem in Extramedullary Multiple Myeloma

Free
Moutaz Helal, Mara John, Emilia Stanojkovska, Greta Mattavelli, Lars Grundheber, Alexander Leipold, Nazia Afrin, Christine Riedhammer, Johannes Duell, Max Johannes Steinhardt, Julia Mersi, Hermann Einsele, Kai Kretzschmar, K. Martin Kortuem, Angela Riedel, Leo Rasche
Journal: Blood
Blood (2022) 140 (Supplement 1): 7060–7061.
https://doi.org/10.1182/blood-2022-168700
Published: 2022