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Dexiu Bu
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Journal Articles

T-Charge™ Manufacturing of the Anti-BCMA CAR-T, Durcabtagene Autoleucel (PHE885), Promotes Expansion and Persistence of CAR-T Cells with High TCR Repertoire Diversity

Shuntaro Ikegawa, Adam S. Sperling, Michela Ansuinelli, Sarah Nikiforow, David Quinn, Dexiu Bu, Jennifer Mataraza, David Pearson, Lawrence Rispoli, Marc A Credi, Nina Orwitz, Yohei Arihara, Rao Prabhala, Lakshmi Bhavani Potluri, Carol Reynolds, Serena De Vita, Nikhil C Munshi, Jerome Ritz
Journal: Blood
Blood (2023) 142 (Supplement 1): 3469.
https://doi.org/10.1182/blood-2023-177721
Published: 2023
Journal Articles

Identification and Development of PHE885: A Novel and Highly Potent Fully Human Anti-BCMA CAR-T Manufactured with a Novel T-Charge TM Platform for the Treatment of Multiple Myeloma

Dexiu Bu, Paul Bennett, Nathaniel Barton, Laura Bradshaw, Maria Pinon-Ortiz, Xiangen Li, Poonam Vaidya, Xu Zhu, Keith Mansfield, Brian Granda, Carla P Guimaraes, Louise M Treanor, Jennifer L Brogdon
Journal: Blood
Blood (2021) 138 (Supplement 1): 2770.
https://doi.org/10.1182/blood-2021-148390
Published: 2021
Journal Articles

Perfecting CAR Engraftment to a Tee (Cell) through Characterization of Single Cell Transcriptome Product and Understanding Neurotoxicity

Wesley Wilson, Fei Miao, Alfred L Garfall, Dexiu Bu, Elena J Orlando, Jennifer L Brogdon, Iulian Pruteanu-Malinici, Adam D Cohen, Michael C. Milone
Journal: Blood
Blood (2021) 138 (Supplement 1): 1707.
https://doi.org/10.1182/blood-2021-151785
Published: 2021
Journal Articles

Phase I Study of PHE885, a Fully Human BCMA-Directed CAR-T Cell Therapy for Relapsed/Refractory Multiple Myeloma Manufactured in <2 Days Using the T-Charge TM Platform

Adam S. Sperling, Sarah Nikiforow, Omar Nadeem, Clifton C Mo, Jacob P. Laubach, Kenneth C. Anderson, Alejandro Alonso, Shuntaro Ikegawa, Rao Prabhala, Diego Hernandez Rodriguez, Heather Daley, Kit L. Shaw, Yohei Arihara, Soudeh Ansari, David S Quinn, David Pearson, Anniesha Hack, Louise M Treanor, Dexiu Bu, Jennifer Mataraza, Lawrence Rispoli, Marc Credi, Jerome Ritz, Serena De Vita, Nikhil C. Munshi
Journal: Blood
Blood (2021) 138 (Supplement 1): 3864.
https://doi.org/10.1182/blood-2021-146646
Published: 2021