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Jennifer L Brogdon
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Journal Articles

CD22-Targeted CAR-Modified T-Cells Safely Induce Remissions in Children and Young Adults with Relapsed, CD19-Negative B-ALL after Treatment with CD19-Targeted CAR T-Cells

Regina M. Myers, Amanda M. DiNofia, Yimei Li, Caroline Diorio, Richard Aplenc, Diane Baniewicz, Jennifer L Brogdon, Colleen Callahan, Boris Engels, Joseph A. Fraietta, Vanessa Gonzalez, Emma Iannone, Allison Barz Leahy, Hongyan Liu, Susan E. McClory, Susan R. Rheingold, Laura Shinehouse, Gerald Wertheim, Lisa Wray, Noelle V. Frey, Shannon L. Maude, Stephan A. Grupp
Journal: Blood
Blood (2022) 140 (Supplement 1): 2376–2377.
https://doi.org/10.1182/blood-2022-168139
Published: 2022
Journal Articles

Decade-Long Remissions of Leukemia Sustained By the Persistence of Activated CD4+ CAR T-Cells

J. Joseph Melenhorst, Gregory M Chen, Meng Wang, David L. Porter, Peng Gao, Shovik Bandyopadhyay, Iulian Pruteanu-Malinici, Christopher L Nobles, Sayantan Maji, Noelle V Frey, Saar Gill, Lifeng Tian, Irina Kulikovskaya, Megan M Davis, Joseph A Fraietta, Jennifer L Brogdon, Regina Young, David E Ambrose, Anne Chew, Bruce L Levine, Don L. Siegel, Cécile Alanio, E. John Wherry, Frederic D. Bushman, Simon F Lacey, Kai Tan, Carl H June
Journal: Blood
Blood (2021) 138 (Supplement 1): 166.
https://doi.org/10.1182/blood-2021-152664
Published: 2021
Journal Articles

Preservation of T-Cell Stemness with a Novel Expansionless CAR-T Manufacturing Process, Which Reduces Manufacturing Time to Less Than Two Days, Drives Enhanced CAR-T Cell Efficacy

Boris Engels, Xu Zhu, Jennifer Yang, Andrew Price, Akash Sohoni, Andrew M Stein, Lana Parent, Michael Greene, Matthew Niederst, Jeanne Whalen, Elena J Orlando, Louise M Treanor, Jennifer L Brogdon
Journal: Blood
Blood (2021) 138 (Supplement 1): 2848.
https://doi.org/10.1182/blood-2021-146246
Published: 2021
Journal Articles

Perfecting CAR Engraftment to a Tee (Cell) through Characterization of Single Cell Transcriptome Product and Understanding Neurotoxicity

Wesley Wilson, Fei Miao, Alfred L Garfall, Dexiu Bu, Elena J Orlando, Jennifer L Brogdon, Iulian Pruteanu-Malinici, Adam D Cohen, Michael C. Milone
Journal: Blood
Blood (2021) 138 (Supplement 1): 1707.
https://doi.org/10.1182/blood-2021-151785
Published: 2021
Journal Articles

Identification and Development of PHE885: A Novel and Highly Potent Fully Human Anti-BCMA CAR-T Manufactured with a Novel T-Charge TM Platform for the Treatment of Multiple Myeloma

Dexiu Bu, Paul Bennett, Nathaniel Barton, Laura Bradshaw, Maria Pinon-Ortiz, Xiangen Li, Poonam Vaidya, Xu Zhu, Keith Mansfield, Brian Granda, Carla P Guimaraes, Louise M Treanor, Jennifer L Brogdon
Journal: Blood
Blood (2021) 138 (Supplement 1): 2770.
https://doi.org/10.1182/blood-2021-148390
Published: 2021
Journal Articles

CART22-65s Co-Administered with huCART19 in Adult Patients with Relapsed or Refractory ALL

Noelle V Frey, Saar Gill, Wei-Ting Hwang, Selina M. Luger, Mary Ellen Martin, Shannon R. McCurdy, Alison W. Loren, Keith W. Pratz, Alexander E. Perl, Julie Barber-Rotenberg, Amy Marshall, Marco Ruella, Simon F Lacey, Joseph Fraietta, Andrew Fesnak, Megan O'brien, Theresa Schanne, Jennifer L Brogdon, Boris Engels, Bruce L Levine, Carl H June, David L Porter, Elizabeth O. Hexner
Journal: Blood
Blood (2021) 138 (Supplement 1): 469.
https://doi.org/10.1182/blood-2021-153955
Published: 2021
Journal Articles

A First-in-Human Study of YTB323, a Novel, Autologous CD19-Directed CAR-T Cell Therapy Manufactured Using the Novel T-Charge TM platform, for the Treatment of Patients (Pts) with Relapsed/Refractory (r/r) Diffuse Large B-Cell Lymphoma (DLBCL)

Ian W. Flinn, Ulrich Jaeger, Nirav N. Shah, Didier Blaise, Javier Briones, Leyla Shune, Nicolas Boissel, Attilio Bondanza, Darlene Lu, Xu Zhu, Boris Engels, Jennifer L Brogdon, Jennifer Mataraza, Jaclyn Davis, Anne Laure Marchal, Luisa Mariconti, Michele Moschetta, Laure Moutouh-de Parseval, Pere Barba, Michael Dickinson
Journal: Blood
Blood (2021) 138 (Supplement 1): 740.
https://doi.org/10.1182/blood-2021-146268
Published: 2021
Journal Articles

Biomarkers of Response to Anti-CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy in Patients with Chronic Lymphocytic Leukemia

Joseph A. Fraietta, PhD, Simon F. Lacey, PhD, Nicholas S Wilcox, Felipe Bedoya, PhD, Fang Chen, PhD, Elena Orlando, PhD, Jennifer L Brogdon, PhD, Wei-Ting Hwang, PhD, Noelle Frey, MD MS, Regina M Young, PhD, Edward Pequignot, M.S., David E Ambrose, BS, Bruce L Levine, PhD, Hans Bitter, PhD, David L Porter, MD, Jun Xu, PhD, Carl H June, MD, Jan Joseph Melenhorst, PhD
Journal: Blood
Blood (2016) 128 (22): 57.
https://doi.org/10.1182/blood.V128.22.57.57
Published: 2016
Journal Articles

Efficacy of Humanized CD19-Targeted Chimeric Antigen Receptor (CAR)-Modified T Cells in Children and Young Adults with Relapsed/Refractory Acute Lymphoblastic Leukemia

Shannon L Maude, MD PhD, David M. Barrett, MD PhD, Susan R. Rheingold, MD, Richard Aplenc, MD PhD, David T Teachey, MD, Colleen Callahan, MSN, Diane Baniewicz, MSN, Claire White, BSN, Mala K. Talekar, MD, Pamela A Shaw, PhD, Jennifer L Brogdon, PhD, Regina M Young, PhD, John Scholler, Katherine T. Marcucci, PhD, Bruce L Levine, PhD, Noelle Frey, MD MS, David L Porter, MD, Simon F. Lacey, PhD, J. Joseph Melenhorst, PhD, Carl H June, MD, Stephan A. Grupp, MD PhD
Journal: Blood
Blood (2016) 128 (22): 217.
https://doi.org/10.1182/blood.V128.22.217.217
Published: 2016
Journal Articles

Histone deacetylase activities are required for innate immune cell control of Th1 but not Th2 effector cell function

Jennifer L. Brogdon, Yongyao Xu, Susanne J. Szabo, Shaojian An, Francis Buxton, Dalia Cohen, Qian Huang
Journal: Blood
Blood (2006) 109 (3): 1123–1130.
https://doi.org/10.1182/blood-2006-04-019711
Published: 2006
Includes: Supplemental data