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Journal Articles

Results from paradigm - a phase 2 randomized multi-center study comparing azacitidine and venetoclax to conventional induction chemotherapy for newly diagnosed fit adults with acute myeloid leukemia

Free
Amir Fathi, Alexander Perl, Geoffrey Fell, Brian Jonas, Brittany Ragon, Alice Mims, Uma Borate, Gabriel Mannis, Karen Quillen, Max Stahl, Paul Koller, Andrew Artz, Monzr M. Al Malki, Guido Marcucci, Mary Linton Peters, Timothy Graubert, Peter Westervelt, Philip Amrein, Hanno Hock, Andrew Brunner, Gabriela Hobbs, Rupa Narayan, Michelle Lee, Brandon Aubrey, Alyssa Watson, Richard Hao, Shilton Dhaver, Michael Grunwald, Yi-Bin Chen, Andrew Matthews, Christopher Hourigan, Brent Wood, Donna Neuberg, Areej El-Jawahri, Ibrahim Aldoss
Journal: Blood
Blood (2025) 146 (Supplement 1): 6.
https://doi.org/10.1182/blood-2025-6
Published: 2025
Journal Articles

Real-world outcomes of myelodysplastic syndrome and chronic myelomonocytic leukemia treated with IDH1 and IDH2 inhibitors in the frontline setting

Free
Alifya Lokhandwala, Cilomar Martins de Oliveira Filho, Philip Amrein, Amir Fathi, Gabriela Hobbs, Hanno Hock, Rupa Narayan, Andrew Brunner, Michelle Lee
Journal: Blood
Blood (2025) 146 (Supplement 1): 8171.
https://doi.org/10.1182/blood-2025-8171
Published: 2025
Journal Articles

Safety and Activity of the TIM3 Inhibitor Sabatolimab in Patients with Lower-Risk Myelodysplastic Syndromes

Free
Andrew M. Brunner, Yiwen Liu, Rupa Narayan, Michelle Hyunju Lee, Philip C. Amrein, Hanno Hock, Gabriela S. Hobbs, Donna S. Neuberg, Timothy Aaron Graubert, Amir T. Fathi
Journal: Blood
Blood (2024) 144 (Supplement 1): 6726.
https://doi.org/10.1182/blood-2024-196718
Published: 2024
Journal Articles

TRK Protein Expression in TP53 Altered Acute Erythroid Leukemia

Free
Rupa Narayan, Ronan T. Swords, Philip C. Amrein, Andrew M. Brunner, Gabriela S. Hobbs, Hanno Hock, Michelle Hyunju Lee, Timothy Aaron Graubert, Amir T. Fathi, Robert P Hasserjian, Valentina Nardi
Journal: Blood
Blood (2024) 144 (Supplement 1): 6154.
https://doi.org/10.1182/blood-2024-211201
Published: 2024
Journal Articles

Retrospective Single-Institution Review of Bosutinib Dose Optimization for Efficacy and Safety with Dose Ramp-up and Titration

Free
Jessica Freydman, David Sirignano, Philip C. Amrein, Meghan Bergeron, Andrew M. Brunner, Elsie Foster, Amir T. Fathi, Timothy Aaron Graubert, Hanno Hock, Michelle Hyunju Lee, Jenna Moran, Rupa Narayan, Gabriela S. Hobbs
Journal: Blood
Blood (2024) 144 (Supplement 1): 6591.
https://doi.org/10.1182/blood-2024-203629
Published: 2024
Journal Articles

Changes in White Blood Cell Counts Early during Treatment of Acute Leukemia Using Differentiating Chemotherapies

Free
Amyah C. Harris, Christopher S. Bell, Gabriela S. Hobbs, Hanno Hock, Philip C. Amrein, Rupa Narayan, Amir T. Fathi, Andrew M. Brunner
Journal: Blood
Blood (2023) 142 (Supplement 1): 1486.
https://doi.org/10.1182/blood-2023-187367
Published: 2023
Journal Articles

Single-Cell Multiomics Analysis Reveals Potential Drivers of Response to the Anti-TIM3 Inhibitor Sabatolimab Combined with Azacitidine in MDS and CMML

Free
Aonkon Dey, Rupa Narayan, Neal Smith, Alice Tirard, Benjamin Arnold, John McGuire, Thomas Chan, Jennifer Lombardi Story, Timothy Casson, Tanya Toni Behnan, Amir T. Fathi, Gabriela S. Hobbs, Hanno Hock, Philip C. Amrein, Patrick Reeves, Timothy Aaron Graubert, Andrew M. Brunner, Alexandra-Chloé Villani
Journal: Blood
Blood (2023) 142 (Supplement 1): 4319.
https://doi.org/10.1182/blood-2023-189858
Published: 2023
Journal Articles

A Phase 2 Study of Lenalidomide in Combination with Mitoxantrone, Etoposide, and Cytarabine (Len plus MEC) in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Free
Manik Razdan Kuchroo, Robert A. Redd, Jacqueline S. Garcia, Michael Keng, Gabriela S. Hobbs, Jacalyn Rosenblatt, Marlise R. Luskin, Rupa Narayan, Philip C. Amrein, Malgorzata McMasters, Martha Wadleigh, Hanno Hock, Richard Stone, Donna S. Neuberg, David Avigan, Karen K. Ballen, Amir T. Fathi, Daniel J. DeAngelo, Andrew M. Brunner
Journal: Blood
Blood (2023) 142 (Supplement 1): 2894.
https://doi.org/10.1182/blood-2023-188182
Published: 2023
Journal Articles

Mini-Hyper-CVD Plus Venetoclax for Treatment of Older Adults with Newly Diagnosed Ph-Negative B-ALL or T-ALL

Free
Marlise R. Luskin, Shai Shimony, Julia Keating, Wendy Stock, Hanno Hock, Jacqueline S. Garcia, Maximilian Stahl, Ilene Galinksy, Rebecca Leonard, Howard Weiner, Yael Flamand, Donna S. Neuberg, Richard M Stone, Anthony G. Letai, Eric S. Winer, Marina Y. Konopleva, Nitin Jain, Daniel J. DeAngelo
Journal: Blood
Blood (2023) 142 (Supplement 1): 2875.
https://doi.org/10.1182/blood-2023-174269
Published: 2023
Journal Articles

Phase II Clinical Trial of Alisertib, an Aurora a Kinase Inhibitor, in Combination with Induction Chemotherapy in High-Risk, Untreated Patients with Acute Myeloid Leukemia

Free
Andrew M. Brunner, MD, Traci M. Blonquist, MS, Daniel J. DeAngelo, MD, Malgorzata McMasters, MD, Eric S. Winer, MD, Gabriela S. Hobbs, MD, Philip C. Amrein, MD, Hanno Hock, MD PhD, David P. Steensma, Jacqueline S. Garcia, Marlise R. Luskin, MD, Richard M. Stone, MD, Karen K. Ballen, MD, Jacalyn Rosenblatt, MD, David E. Avigan, MD, Steven L McAfee, MD, Jenna A. Moran, NP, Meghan Bergeron, Julia Foster, ANP, Christina Bertoli, Kristin McGregor, Kaitlyn Fishman, Molly Macrae, Meghan Burke, Tanya T. Behnan, BS, Tina T. Som, RN, Aura Y. Ramos, Megan K. Vartanian, RN, Nicole Nelson, Emma Logan, Jennifer Lombardi Story, Christine Connolly, Donna S Neuberg, ScD, Yi-Bin Chen, MD, Timothy A. Graubert, MD, Amir T. Fathi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 766.
https://doi.org/10.1182/blood-2018-99-115145
Published: 2018
Journal Articles

Phase I Study of the Antibody-Drug Conjugate Brentuximab Vedotin Combined with Re-Induction Chemotherapy in Patients with CD30-Expressing Relapsed/Refractory Acute Myeloid Leukemia

Free
Amir T. Fathi, MD, Traci M. Blonquist, MS, Ashkan Emadi, MD PhD, Andrew M. Brunner, MD, Gabriela S. Hobbs, MD, Hanno Hock, MD PhD, Steven L McAfee, MD, Robert P. Hasserjian, MD, Frederic I. Preffer, PhD, Jenna A. Moran, NP, Meghan Bergeron, Julia Foster, ANP, Christina Bertoli, Kristin McGregor, Kaitlyn Fishman, Molly Macrae, Meghan Burke, Tanya T. Behnan, BS, Tina T. Som, RN, Aura Y. Ramos, Megan K. Vartanian, RN, Jennifer Lombardi Story, Patricia Lesho, Vu H. Duong, MD, Mason Mann, Christopher Lescinskas, Christine Connolly, Donna S Neuberg, ScD, Karen K. Ballen, MD, Philip C. Amrein, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1431.
https://doi.org/10.1182/blood-2018-99-115031
Published: 2018
Journal Articles

Phase I Study of Ixazomib in Addition to Chemotherapy for the Treatment of Acute Lymphoblastic Leukemia in Older Adults

Free
Philip C. Amrein, MD, Karen K. Ballen, MD, Traci M. Blonquist, MS, Andrew M. Brunner, MD, Gabriela S. Hobbs, MD, Hanno Hock, MD PhD, Steven L McAfee, MD, Jenna A. Moran, NP, Meghan Bergeron, Julia Foster, ANP, Christina Bertoli, Kristin McGregor, Molly Macrae, Meghan Burke, Tanya T. Behnan, BS, Tina T. Som, RN, Aura Y. Ramos, Megan K. Vartanian, RN, Jennifer Lombardi Story, Christine Connolly, Donna S Neuberg, ScD, Amir T. Fathi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2704.
https://doi.org/10.1182/blood-2018-99-117506
Published: 2018
Journal Articles

Phase I Study of Ixazomib in Addition to Chemotherapy for the Treatment of Acute Myeloid Leukemia in Older Adults

Free
Philip C. Amrein, MD, Eyal C. Attar, MD, Traci M. Blonquist, MS, Andrew M. Brunner, MD, Gabriela S. Hobbs, MD, Hanno Hock, MD PhD, Steven McAfee, MD, Jenna A. Moran, NP, Meghan Bergeron, Julia Foster, ANP, Christina Bertoli, Kristin McGregor, Molly Macrae, Meghan Burke, Tanya T. Behnan, BS, Tina T. Som, RN, Aura Y. Ramos, Megan K. Vartanian, RN, Jennifer Lombardi Story, Donna S Neuberg, ScD, Amir T. Fathi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4059.
https://doi.org/10.1182/blood-2018-99-117566
Published: 2018
Journal Articles

Risk Factors and Impact of Neurological Complications after Allogeneic Hematopoietic Stem Cell Transplantation

Free
Mark R. Dowling, MBBS, PhD, Shuli Li, Ashmeet Bhatia, MD, Areej El-Jawahri, MD, Bimal R. Dey, MD PhD, Steven L. McAfee, MD, Hanno Hock, MD PhD, Thomas R. Spitzer, MD, Yi-Bin Chen, MD, Karen K. Ballen, MD
Journal: Blood
Blood (2016) 128 (22): 5742.
https://doi.org/10.1182/blood.V128.22.5742.5742
Published: 2016
Journal Articles

The Impact of Regional Cardiovascular Care Outcomes on Survival and Cardiovascular-Specific Mortality in Myelodysplastic Syndrome

Free
Andrew M. Brunner, MD, Traci M. Blonquist, MS, Gabriela Soriano Hobbs, MD, Philip C. Amrein, MD, Hanno Hock, MDPhD, Karen K. Ballen, MD, Donna S. Neuberg, ScD, Amir T. Fathi, MD
Journal: Blood
Blood (2016) 128 (22): 5984.
https://doi.org/10.1182/blood.V128.22.5984.5984
Published: 2016
Journal Articles

The Balance of Gfi-1 and Gfi-1b Maintains the Undifferentiated, Multipotent State of Hematopoietic Stem Cells and Regulates Lineage-Commitment

Free
Adlen Foudi, PhD, Hanno Hock, MD PhD
Journal: Blood
Blood (2012) 120 (21): 1210.
https://doi.org/10.1182/blood.V120.21.1210.1210
Published: 2012