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Yi-Bin Chen
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Journal Articles

Safety and Efficacy of the Glucagon-like Peptide 2 (GLP-2) Analog Apraglutide in Patients with Steroid-Refractory Gastrointestinal Acute Graft-Versus-Host Disease (aGvHD) in Combination with Best Available Therapy: Results from a Multicenter, Randomized, Single-Blind, Proof-of-Concept, Phase 2 Stargaze Trial

Robert Zeiser, Hannah Choe, Holger Adelmann, Nader N. Youssef, Anastasia Eremeeva, François Collin, Yi-Bin Chen
Journal: Blood
Blood (2024) 144 (Supplement 1): 100.
https://doi.org/10.1182/blood-2024-198360
Published: 2024
Journal Articles

Long Term Outcomes of a Randomized Trial of Anti-T Lymphocyte Globulin to Improve Moderate-Severe Chronic Gvhd Free Survival after Unrelated Donor Hematopoietic Cell Transplantation: A CIBMTR Analysis

Robert J. Soiffer, Mitchell Horwitz, Joseph P. McGuirk, Sudhindra Rao, Peter Westervelt, John F. DiPersio, Laura Johnston, Jonathan Serody, Witold B Rybka, Paul Shaughnessy, Joseph A. Pidala, Vincent Ho, Andrew Artz, Madhuri Vusirikala, David L. Porter, Paul J. Martin, David Avigan, Michael R Bishop, Ran Reshef, Andrew Peterson, Kwang Wooahn, Adetola A. Kassim, Ryotaro Nakamura, Yi-Bin Chen, Linda Burns
Journal: Blood
Blood (2024) 144 (Supplement 1): 4911.
https://doi.org/10.1182/blood-2024-205572
Published: 2024
Journal Articles

TSC-100 and TSC-101 Demonstrate the Potential to Reduce Relapse Rates and Increase Relapse-Free Survival in Patients with AML, ALL, or MDS Undergoing Allogeneic HCT with Reduced Intensity Conditioning (RIC): Preliminary Results from the Phase 1 Alloha Trial

MHD Monzr M. Al Malki, Alla Keyzner, Uday Popat, Yi-Bin Chen, Hyung C Suh, Tania Jain, Melhem M. Solh, Anson Snow, Saar Gill, Lohith Gowda, Joseph Uberti, Erica Buonomo, Yun Wang, Nancy Nabilsi, Timothy White, Cuong Nguyen, Jim Murray, Gavin MacBeath, Chrystal Louis, Shrikanta Chattopadhyay, Michelle Matzko, Ran Reshef
Journal: Blood
Blood (2024) 144 (Supplement 1): 924.
https://doi.org/10.1182/blood-2024-201526
Published: 2024
Journal Articles

Molecular Residual Disease Detection Via Cancer Personalized Profiling By Deep Sequencing in Patients with PTCL Undergoing Autologous Stem Cell Transplantation

Chandan Sanghera, Josie Ford, Ruwan Gunaratne, Kusha Chopra, Anna B Rider, Aliyah R. Sohani, Sean M McCabe, Ronald A Nemec, Yi-Bin Chen, Steven McAfee, Ephraim Hochberg, Jeffrey A. Barnes, Caroline MacVicar, Eric D. Jacobsen, Mwanasha H. Merrill, Michael S. Khodadoust, David Kurtz, Salvia Jain
Journal: Blood
Blood (2024) 144 (Supplement 1): 6202.
https://doi.org/10.1182/blood-2024-206116
Published: 2024
Journal Articles

Refinement of Day 28 Treatment Response Criteria for Acute GVHD: A Collaboration Study of the JSTCT and MAGIC

Yu Akahoshi, Yoshihiro Inamoto, Nikolaos Spyrou, Hideki Nakasone, Francis A. Ayuk, Hannah Choe, Noriko Doki, Tetsuya Eto, Aaron Etra, Elizabeth O. Hexner, Nobuhiro Hiramoto, William J. Hogan, Ernst Holler, Keisuke Kataoka, Masatsugu Tanaka, Takashi Tanaka, Naoyuki Uchida, Ingrid Vasova, Fumihiko Ishimaru, Takahiro Fukuda, Yi-Bin Chen, Junya Kanda, Ryotaro Nakamura, Yoshiko Atsuta, James L.M. Ferrara, Yoshinobu Kanda, John Levine, Takanori Teshima
Journal: Blood
Blood (2024) 144 (Supplement 1): 384.
https://doi.org/10.1182/blood-2024-203344
Published: 2024
Journal Articles

Phase 1 study of CAR-37 T cells in patients with relapsed or refractory CD37 + lymphoid malignancies

Clinical Trials & Observations
Matthew J. Frigault, Charlotte E. Graham, Trisha R. Berger, Julie Ritchey, Nora K. Horick, Areej El-Jawahri, Irene Scarfò, Andrea Schmidts, Nicholas J. Haradhvala, Marc Wehrli, Won-Ho Lee, Aiyana L. Parker, Hadley R. Wiggin, Amanda Bouffard, Aonkon Dey, Mark B. Leick, Katelin Katsis, Eva L. Elder, Maria A. Dolaher, Daniella T. Cook, Alena A. Chekmasova, Lu Huang, Sarah Nikiforow, Heather Daley, Jerome Ritz, Myriam Armant, Fred Preffer, John F. DiPersio, Valentina Nardi, Yi-Bin Chen, Kathleen M. E. Gallagher, Marcela V. Maus
Journal: Blood
Blood (2024) 144 (11): 1153–1167.
https://doi.org/10.1182/blood.2024024104
Published: 2024
Includes: Supplemental data
Journal Articles

Novel MAGIC composite scores using both clinical symptoms and biomarkers best predict treatment outcomes of acute GVHD

Clinical Trials & Observations
Yu Akahoshi, Nikolaos Spyrou, Daniela Weber, Paibel Aguayo-Hiraldo, Francis Ayuk, Chantiya Chanswangphuwana, Hannah K. Choe, Matthias Eder, Aaron M. Etra, Stephan A. Grupp, Elizabeth O. Hexner, William J. Hogan, Carrie L. Kitko, Sabrina Kraus, Monzr M. Al Malki, Pietro Merli, Muna Qayed, Ran Reshef, Tal Schechter, Evelyn Ullrich, Ingrid Vasova, Matthias Wölfl, Robert Zeiser, Janna Baez, Rahnuma Beheshti, Gilbert Eng, Sigrun Gleich, Nikolaos Katsivelos, Steven Kowalyk, George Morales, Rachel Young, Yi-Bin Chen, Ryotaro Nakamura, John E. Levine, James L. M. Ferrara
Journal: Blood
Blood (2024) 144 (9): 1010–1021.
https://doi.org/10.1182/blood.2024025106
Published: 2024
Includes: Supplemental data
Journal Articles

Spatial transcriptomics reveals distinct tissue niches linked with steroid responsiveness in acute gastrointestinal GVHD

Bidish K. Patel, Michael J. Raabe, Evan R. Lang, Yuhui Song, Chenyue Lu, Vikram Deshpande, Linda T. Nieman, Martin J. Aryee, Yi-Bin Chen, David T. Ting, Zachariah DeFilipp
Journal: Blood
Blood (2023) 142 (21): 1831–1844.
https://doi.org/10.1182/blood.2023020644
Published: 2023
Includes: Supplemental data
Journal Articles

Multi-Site Randomized Trial of Inpatient Palliative Care for Hospitalized Patients Undergoing Hematopoietic Stem Cell Transplantation

Areej El-Jawahri, Thomas W LeBlanc, Alison Kavanaugh, Jason Webb, James Fausto, Lara Traeger, Joseph Greer, Vicki Jackson, Nora Horick, Zachariah Defilipp, Yi-Bin Chen, Stephanie J. Lee, Jennifer Temel
Journal: Blood
Blood (2023) 142 (Supplement 1): 913.
https://doi.org/10.1182/blood-2023-185735
Published: 2023
Journal Articles

Updated Findings of a Phase II Study of Ruxolitinib Pre-, during- and Post-Hematopoietic Stem Cell Transplantation for Patients with Primary or Secondary Myelofibrosis

Gabriela S. Hobbs, Haesook T. Kim, Suzanne O'Connor, Mark A. Schroeder, Roni Tamari, Sarah A Wall, Areej El-Jawahri, Steven McAfee, Jessica Hem, Patricia Lozano, Jonas S. Jutzi, Ann Mullally, Yi-Bin Chen, Zachariah Defilipp
Journal: Blood
Blood (2023) 142 (Supplement 1): 2103.
https://doi.org/10.1182/blood-2023-178645
Published: 2023
Journal Articles

Measurable Residual IDH2 before Allogeneic Transplant for Acute Myeloid Leukemia

Gege Gui, Laura W Dillon, Niveditha Ravindra, Pranay S. Hegde, Georgia Andrew, Devdeep Mukherjee, Zoe Wong, Jeffery J. Auletta, Firas El Chaer, Evan C. Chen, Yi-Bin Chen, Adam Corner, Steven M. Devine, Sunil G. Iyer, Antonio M. Jimenez Jimenez, Marcos de Lima, Mark R. Litzow, Partow Kebriaei, Wael Saber, Stephen R. Spellman, Scott L. Zeger, Kristin M. Page, Christopher S. Hourigan
Journal: Blood
Blood (2023) 142 (Supplement 1): 424.
https://doi.org/10.1182/blood-2023-186822
Published: 2023
Journal Articles

Post-Hoc Analysis of Measurable Residual Disease from BMT-CTN 1506/Morpho: FLT3-ITD Variant Allele Frequency and Survival Are Highly Correlated

Mark J. Levis, Mehdi Hamadani, Brent R. Logan, Richard J. Jones, Anurag K. Singh, Mark R. Litzow, John R. Wingard, Esperanza B. Papadopoulos, Alexander Perl, Robert J. Soiffer, Celalettin Ustun, Masumi Ueda Oshima, Geoffrey L Uy, Edmund K. Waller, Sumithira Vasu, Melhem M. Solh, Asmita Mishra, Lori S. Muffly, Hee-Je Kim, Matthias Stelljes, Yuho Najima, Masahiro Onozawa, Kirsty Thomson, Arnon Nagler, Andrew H. Wei, Guido Marcucci, Nahla Hasabou, Mathew Rosales, Jason Hill, Stanley C. Gill, Rishita Nuthethi, Denise King, Heather Wittsack, Adam Mendizabel, Steven M. Devine, Mary M. Horowitz, Yi-Bin Chen
Journal: Blood
Blood (2023) 142 (Supplement 1): 973.
https://doi.org/10.1182/blood-2023-177929
Published: 2023
Journal Articles

A Personalized Whole Genome-Informed Assay Targeting Single Mutant in Circulating Tumor DNA Can Identify MRD and Predict Relapse in DLBCL

Reid W. Merryman, Justin Rhoades, Kan Xiong, Katherine Antel, Hyun Hwan An, Robert A. Redd, Mikaela M. McDonough, Lillian Guerrero, Andela Crnjac, Sainetra Sridhar, Timothy Blewett, Ju Chen, Parastoo B. Dahi, Yago Nieto, Yi-Bin Chen, Alex F. Herrera, Robin M. Joyce, Philippe Armand, Mark Alan Murakami, Viktor Adalsteinsson
Journal: Blood
Blood (2023) 142 (Supplement 1): 527.
https://doi.org/10.1182/blood-2023-189962
Published: 2023
Journal Articles

A Day 14 Endpoint for Acute Gvhd Clinical Trials

Nikolaos Spyrou, Yu Akahoshi, Steven Kowalyk, George Morales, Rahnuma Beheshti, Paibel Aguayo-Hiraldo, MHD Monzr Al Malki, Francis Ayuketang Ayuk, Peter Bader, Janna Baez, Alexandra Capellini, Hannah Choe, Zachariah Defilipp, Matthias Eder, Gilbert Eng, Aaron Etra, Sigrun Gleich, Stephan Grupp, Elizabeth Hexner, Matthias Hoepting, William J. Hogan, Stelios Kasikis, Nikolaos Katsivelos, Carrie L. Kitko, Sabrina Kraus, Deukwoo Kwon, Pietro Merli, Joseph Portelli, Muna Qayed, Ran Reshef, Tal Schechter-Finkelstein, Ingrid Vasova, Matthias Woelfl, Kitsada Wudhikarn, Rachel Young, Ernst Holler, Yi-Bin Chen, Ryotaro Nakamura, John Levine, James L.M. Ferrara
Journal: Blood
Blood (2023) 142 (Supplement 1): 779.
https://doi.org/10.1182/blood-2023-172955
Published: 2023
Journal Articles

Measurable Residual IDH1 before Allogeneic Transplant for Acute Myeloid Leukemia

Gege Gui, Laura W Dillon, Niveditha Ravindra, Pranay S. Hegde, Georgia Andrew, Devdeep Mukherjee, Zoe Wong, Jeffery J. Auletta, Firas El Chaer, Evan C. Chen, Yi-Bin Chen, Adam Corner, Steven M. Devine, Sunil G. Iyer, Antonio M. Jimenez Jimenez, Marcos de Lima, Mark R. Litzow, Partow Kebriaei, Wael Saber, Stephen R. Spellman, Scott L. Zeger, Kristin M. Page, Christopher S. Hourigan
Journal: Blood
Blood (2023) 142 (Supplement 1): 4316.
https://doi.org/10.1182/blood-2023-186376
Published: 2023
Journal Articles

A Phase II Multicenter Trial of Ruxolitinib to Treat Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Cell Transplantation

Zachariah Defilipp, Haesook T. Kim, Guang-Shing Cheng, Saurabh Chhabra, Mehdi Hamadani, Karamjeet S. Sandhu, Betty K. Hamilton, Lia Perez, Catherine J. Lee, Timothy L Brennan, Cassandra Garrelts, Bergin M Brown, Kathleen Gallagher, Areej El-Jawahri, Yi-Bin Chen
Journal: Blood
Blood (2023) 142 (Supplement 1): 775.
https://doi.org/10.1182/blood-2023-179365
Published: 2023
Journal Articles

Effective Prevention of Steroid-Requiring Chronic Graft-Vs.-Host Disease with B Cell Depletion: A Randomized, Placebo-Controlled Trial

Corey Cutler, Haesook T. Kim, Hassan El Banna, Elizabeth Halloran, Emily Matozel, Vincent Ho, John Koreth, Mahasweta Gooptu, Roman M. Shapiro, Amar H Kelkar, Christopher James Gibson, Carol Reynolds, Michela Ansuinelli, Rayuko Tamada, Chloe Au, Zachariah Defilipp, Areej El-Jawahri, Yi-Bin Chen, Najla H El Jurdi, Daniel Weisdorf, Daniel R. Couriel, Catherine J. Lee, Bita Sahaf, Juliana Craig, Kathleen Ji, Robert J. Soiffer, David B. Miklos, Joseph Antin, Jerome Ritz
Journal: Blood
Blood (2023) 142 (Supplement 1): 649.
https://doi.org/10.1182/blood-2023-180142
Published: 2023
Journal Articles

Chimeric Antigen Receptor T-Cell (CAR-T) Therapy in Secondary Central Nervous System Large B-Cell Lymphoma (SCNSL): A Multicenter Retrospective Analysis

Gulrayz Ahmed, Aseel Alsouqi, Aniko Szabo, Alexandra E. Rojek, Peter A. Riedell, Farrukh T. Awan, Laura Samples, Mazyar Shadman, Marie Hu, Veronika Bachanova, William Wesson, Nausheen Ahmed, Madiha Iqbal, Mohamed A. Kharfan-Dabaja, Michael Scordo, Patrick Connor Johnson, Yi-Bin Chen, Sawa Ito, Mehdi Hamadani, Matthew J. Frigault
Journal: Blood
Blood (2023) 142 (Supplement 1): 3088.
https://doi.org/10.1182/blood-2023-184345
Published: 2023
Journal Articles

Flares of Acute Graft-Versus-Host Disease: Mount Sinai Acute Gvhd International Consortium (MAGIC) Study

Yu Akahoshi, Nikolaos Spyrou, Daniela Weber, Paibel Aguayo-Hiraldo, Francis A. Ayuk, Udomsak Bunworasate, Hannah Choe, Matthias Eder, Aaron Etra, Stephan Grupp, Elizabeth O Hexner, William J. Hogan, Carrie L. Kitko, Sabrina Kraus, Pietro Merli, Muna Qayed, Ran Reshef, Tal Schechter-Finkelstein, Evelyn Ullrich, Ingrid Vasova, Matthias Woelfl, Robert Zeiser, Janna Baez, Rahnuma Beheshti, Sigrun Gleich, Nikolaos Katsivelos, Steven Kowalyk, George Morales, Rachel Young, Yi-Bin Chen, James L.M. Ferrara, John Levine, Ryotaro Nakamura
Journal: Blood
Blood (2023) 142 (Supplement 1): 776.
https://doi.org/10.1182/blood-2023-181900
Published: 2023
Journal Articles

Multimodal Mobile Application to Address Sexual Dysfunction in Hematopoietic Stem Cell Transplant (HCT) Survivors

Areej El-Jawahri, Jennifer Reese, Lara Traeger, Don Dizon, Sharon Bober, Julie Vanderklish, Richard Newcomb, Zachariah Defilipp, Yi-Bin Chen, Jennifer Temel
Journal: Blood
Blood (2023) 142 (Supplement 1): 5142.
https://doi.org/10.1182/blood-2023-185776
Published: 2023