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Journal Articles

Discovery of the transcription factor ZNF683/hobit as a central regulator of pathogenic T cell proliferation in acute gvhd

Free
Alexandre Albanese, Edward Chen, Yvonne Suessmuth, Jiayi Dong, James Kaminski, Lev Gorfinkel, Ally Eran, Jillian Zavistaski, Lorenzo Cagnin, Paul Keskula, Brandi Bratrude, Kayla Betz, Elham Rayzan, Muna Qayed, John Horan, Amelia Langston, Benjamin Watkins, Bruce Blazar, Leslie Kean
Journal: Blood
Blood (2025) 146 (Supplement 1): 275.
https://doi.org/10.1182/blood-2025-275
Published: 2025
Journal Articles

Mismatching of unrelated donors beyond a single HLA-locus does not adversely impact outcomes at one year following transplantation: Results from the NMDP sponsored ACCESS study

Free
Monzr M. Al Malki, Stephanie Bo-Subait, Brent Logan, Sarah Smith, Erin Leckrone, Heather Stefanski, Jeffery Auletta, Stephen Spellman, Craig Malmberg, Medhat Askar, Rachel Cusatis, Brian Shaffer, Dipenkumar Modi, Farhad Khimani, Mahasweta Gooptu, Mehdi Hamadani, Martin Maiers, Joseph Stanek, Javier Meade, Uttam Rao, Jordan Milner, Ramzi Abboud, Katarzyna Jamieson, George Carrum, Bhagirathbhai Dholaria, William Hogan, Ran Reshef, Satyajit Kosuri, Rachel Cook, Karen Ballen, Alison Loren, Karilyn Larkin, Sally Arai, Muna Qayed, Sung Choi, Larisa Broglie, Bronwen Shaw, Steven Devine, Antonio Jimenez Jimenez
Journal: Blood
Blood (2025) 146 (Supplement 1): 936.
https://doi.org/10.1182/blood-2025-936
Published: 2025
Journal Articles

Overlap of post-CAR T HLH toxicity definitions and their prognostic significance in children and young adults with B-acute lymphoblastic leukemia

Free
Kevin McNerney, Soyang Kwon, Swati Naik, Vanessa Fabrizio, Gabriela Llaurador Caraballo, Lazaro Sanchez-Pinto, Aimee Talleur, Xiaopei Lily Zeng, Christina Baggott, Anant Vatsayan, Michael Verneris, Snehit Prabhu, Jenna Rossoff, Holly Pacenta, Christine Phillips, Julie-An Talano, Amy Moskop, Douglas Myers, Nicole Karras, Challice Bonifant, Muna Qayed, Prakash Satwani, William Temple, Christa Krupski, Amy Keating, Susanne Baumeister, Emily Egeler, Sharon Mavroukakis, Kevin Curran, Crystal Mackall, Theodore Laetsch, Rebecca Gardner, Liora Schultz
Journal: Blood
Blood (2025) 146 (Supplement 1): 4501.
https://doi.org/10.1182/blood-2025-4501
Published: 2025
Journal Articles

Peripheral blast count at apheresis as a risk factor for survival following tisagenlecleucel in children and young adults

Free
Kaylyn Lyons, Kristen Miller, Arpita Deb, Andrew Nicklawsky, Christina Baggott, Khanh Nguyen, Snehit Prabhu, Holly Pacenta, Christine Phillips, Jenna Rossoff, Heather Stefanski, Julie-An Talano, Amy Moskop, Amy Keating, Susanne Baumeister, Douglas Myers, Nicole Karras, Stacy Cooper, Muna Qayed, Michelle Hermiston, Prakash Satwani, Christa Krupski, Vasant Chinnabhandar, Crystal Mackall, Samuel John, Theodore Laetsch, Kevin Curran, Michael Verneris, Liora Schultz, Vanessa Fabrizio
Journal: Blood
Blood (2025) 146 (Supplement 1): 7638.
https://doi.org/10.1182/blood-2025-7638
Published: 2025
Journal Articles

Investigating belumosudil in children with refractory moderate-to-severe chronic graft-versus-host disease: Design of a phase 1/2 study

Free
Kirk Schultz, Adriana Balduzzi, Marta Vicent, Muna Qayed, Fausto Loberiza, Lauren Rota, Cathy Cantalloube, Paul Carpenter
Journal: Blood
Blood (2025) 146 (Supplement 1): 7753.
https://doi.org/10.1182/blood-2025-7753
Published: 2025
Journal Articles

Grade I acute graft-vs-host disease: Treat or not?

Free
Yu Akahoshi, Nikolaos Katsivelos, Ioannis Evangelos Louloudis, Daniela Weber, Francis Ayuk, William Hogan, Yi-Bin Chen, Aaron Etra, Paibel Aguayo-Hiraldo, Chantiya Chanswangphuwana, Hannah Choe, Elizabeth Hexner, Carrie Kitko, Monzr M. Al Malki, Pietro Merli, Timothy Olson, Muna Qayed, Ingrid Vasova, Matthias Woelfl, Janna Baez, Gilbert Eng, Sigrun Gleich, George Morales, Nikolaos Spyrou, Rachel Young, Ryotaro Nakamura, James Ferrara, John Levine
Journal: Blood
Blood (2025) 146 (Supplement 1): 2461.
https://doi.org/10.1182/blood-2025-2461
Published: 2025
Journal Articles

Phase II Study of post transplant cyclophosphamide-based graft versus host disease prophylaxis after HLA-mismatched unrelated donor transplantation and reduced intensity conditioning: Results from the NMDP-sponsored access expansion Study

Free
Mahasweta Gooptu, Monzr M. Al Malki, Stephanie Bo-Subait, Brent Logan, Erin Leckrone, Sarah Smith, Heather Stefanski, Jeffery Auletta, Stephen Spellman, Craig Malmberg, Medhat Askar, Rachel Cusatis, Farhad Khimani, Dipenkumar Modi, Mehdi Hamadani, Martin Maiers, Joseph Stanek, Javier Meade, Uttam Rao, Jordan Milner, Ramzi Abboud, Katarzyna Jamieson, George Carrum, Bhagirathbhai Dholaria, William Hogan, Ran Reshef, Satyajit Kosuri, Rachel Cook, Karen Ballen, Alison Loren, Karilyn Larkin, Sally Arai, Muna Qayed, Sung Choi, Larisa Broglie, Bronwen Shaw, Steven Devine, Antonio Jimenez Jimenez, Brian Shaffer
Journal: Blood
Blood (2025) 146 (Supplement 1): 4232.
https://doi.org/10.1182/blood-2025-4232
Published: 2025
Journal Articles

T cell receptor costimulation blockade effectively prevents acute graft versus host disease without reducing the size or diversity of the T cell immune repertoire

Free
Chiara Wychera, Alexandre Albanese, Steven Siegel, Joseph Schmalz, Stephanie Bien, Brandi Bratrude, Kayla Betz, Lev Gorfinkel, Lorenzo Cagnin, Paul Keskula, Bruce Blazar, Muna Qayed, John Horan, Amelia Langston, Benjamin Watkins, Leslie Kean
Journal: Blood
Blood (2025) 146 (Supplement 1): 819.
https://doi.org/10.1182/blood-2025-819
Published: 2025
Journal Articles

Distinct Biological Subtypes of Chronic GVHD after Pediatric Hematopoietic Cell Transplantation

Open Access
Bernard Ng, Andrew C. Harris, Sayeh Abdossamadi, Geraldine Aubert, Rajinder P. Bajwa, Monica Bhatia, Henrique Bittencourt, Nataliya Prokopenko Buxbaum, Emi H. Caywood, Sonali Chaudhury, Joseph H Chewning, Sung Won Choi, Ashley Chopek, Julia Chu, Donald Coulter, Shahinaz M Gadalla, Richard T Hogg, David A Jacobsohn, Amanda K Johnson, Michael Joyce, Kimberly A. Kasow, Michael Kent, Carrie L. Kitko, Donna Lau, Anita Lawitschka, Victor Anthony Lewis, Amanda M Li, Laura Michelle McLaughlin, David Mitchell, Eneida R. Nemecek, Vaishnavi Parthasarathy, Anna B Pawlowska, Filip Pirsl, Michael A. Pulsipher, Muna Qayed, Jacob Rozmus, Süreyya Savaşan, Tal Schechter, Shalini Shenoy, Alima Suleimenova, Dong Jun Zheng, Elena Ostroumov, Andrew Gilman, Ramon I Klein Geltink, Daniel Wolff, Geoffrey D.E. Cuvelier, Kirk R. Schultz
Journal: Blood
Blood blood.2025028625.
https://doi.org/10.1182/blood.2025028625
Published: 2025
Includes: Supplemental data
Journal Articles

Pentostatin Low-Dose TBI Is an Effective Conditioning Regimen That Permits Donor Engraftment in Patients with High Co-Morbidities Undergoing the First Transplant or Prior to a Second Transplant

Free
Ani Gvajaia, Joseph Rimando, William Blum, Colin A. Vale, Cynthia R. Giver, Elaina L. Corbett, Kevin Hall, Kristina Murphy, Mary Jo Lechowicz, Michel Conn, Minal Surati, Muna Qayed, Amelia Langston, Edmund K. Waller
Journal: Blood
Blood (2024) 144 (Supplement 1): 7325.
https://doi.org/10.1182/blood-2024-211880
Published: 2024
Journal Articles

Role of B Cell Recovery in Relapse Risk and CD19 Phenotype Following Real-World Use of Tisagenlecleucel for Pediatric B-Acute Lymphoblastic Leukemia: A Multi-Institutional Retrospective Study

Free
Xiaopei Lily Zeng, Soyang Kwon, Anant Vatsayan, Christina Baggott, Snehit Prabhu, Samuel John, Holly L. Pacenta, Christine L. Phillips, Jenna Rossoff, Julie-An Talano, Amy Moskop, Michael R Verneris, Douglas D. Myers, Erin Marie Hall, Nicole A Karras, Challice L. Bonifant, Muna Qayed, Michelle L. Hermiston, Prakash Satwani, Christa Krupski, Amy K Keating, Susanne H.C. Baumeister, Vanessa A. Fabrizio, Vasant Chinnabhandar, Emily Egeler, Sharon Mavroukakis, Khanh Nguyen, Kevin J. Curran, Crystal L. Mackall, Theodore W. Laetsch, Liora Michal Schultz, Kevin O. McNerney
Journal: Blood
Blood (2024) 144 (Supplement 1): 2817.
https://doi.org/10.1182/blood-2024-211231
Published: 2024
Journal Articles

The Impact of Structural Inequity and Adverse Social Determinants of Health on Hematopoietic Cell Transplant Access in Pediatric Patients with Hematologic Malignancies and Myelodysplastic Syndromes

Free
Erin Frost, Adrianna Westbrook, Tracy Huang, Muna Qayed, Benjamin Watkins, Kirsten M. Williams, Alan Bidgoli, Michelle L Schoettler
Journal: Blood
Blood (2024) 144 (Supplement 1): 2366.
https://doi.org/10.1182/blood-2024-211117
Published: 2024
Journal Articles

Five-Year Outcomes of the “Abatacept Combined with a Calcineurin Inhibitor and Methotrexate for Graft Versus Host Disease (GVHD) Prophylaxis: A Randomized Controlled Trial” (‘ABA2‘)

Free
Lev Gorfinkel, Muna Qayed, Brandi Bratrude, Kayla Betz, Kyle Hebert, Sung W. Choi, Jeffrey Davis, Christine Duncan, Roger H. Giller, Michael S. Grimley, Andrew Harris, David A Jacobsohn, Nahal Lalefar, Nosha Farhadfar, Michael A. Pulsipher, Shalini Shenoy, Aleksandra Petrovic, Kirk R. Schultz, Gregory Yanik, Bruce R Blazar, John T. Horan, Amelia Langston, Leslie Kean, Benjamin Watkins
Journal: Blood
Blood (2024) 144 (Supplement 1): 3516.
https://doi.org/10.1182/blood-2024-205130
Published: 2024
Journal Articles

Terminal Complement Activation in Children with Sinusoidal Obstructive Syndrome after Hematopoietic Cell Transplantation

Free
Michelle L Schoettler, Jayre Jones, William Briones, Elyse Bryson, Muna Qayed, Seema R Patel, Katherine Silvis, Adrianna Westbrook, Kirsten M. Williams, Satheesh Chonat
Journal: Blood
Blood (2024) 144 (Supplement 1): 3509.
https://doi.org/10.1182/blood-2024-205482
Published: 2024
Journal Articles

Serial Clinical and Biomarker Monitoring during Treatment Can Stratify Patients with Low Risk Gvhd

Free
Nikolaos Katsivelos, Nikolaos Spyrou, Daniela Weber, Ingrid Vasova, Francis A. Ayuk, Hannah Choe, William J. Hogan, Zachariah Defilipp, Muna Qayed, Aaron Etra, Karamjeet S Sandhu, Sabrina Kraus, Timothy S. Olson, Elizabeth O. Hexner, Paibel Aguayo-Hiraldo, Ran Reshef, Evelyn Ullrich, Tal Schechter-Finkelstein, Carrie L. Kitko, Chantiya Chanswangphuwana, Pietro Merli, Yu Akahoshi, Janna Baez, Gilbert Eng, Rahnuma Beheshti, Steven Kowalyk, George Morales, Ioannis Evangelos Louloudis, Rachel Young, Ernst Holler, Ryotaro Nakamura, James L.M. Ferrara, John Levine
Journal: Blood
Blood (2024) 144 (Supplement 1): 380.
https://doi.org/10.1182/blood-2024-204010
Published: 2024
Journal Articles

Impact of Current Manufacturing on Kymriah Real-World Effectiveness and Functional Persistence in Acute Lymphoblastic Leukemia (ALL) (KareALL): A Retrospective Study of Tisagenlecleucel (tisa-cel)-Treated Pediatric and Young Adult Patients (pts) with ALL

Free
Rayne Rouce, J. Gregory Dolan, Christine L. Phillips, Muna Qayed, Michael A. Pulsipher, Lauren M. Vernau, Thomas J. Galletta, Sarah Votaw, Gabriela Llaurador Caraballo, Hongbo Yang, Yao Wang, Shashank Ghantoji, Mimi Tesfaye, Soyon Lee, Emer O'Sullivan, Stephan A. Grupp
Journal: Blood
Blood (2024) 144 (Supplement 1): 7724.
https://doi.org/10.1182/blood-2024-203376
Published: 2024
Journal Articles

A Pilot Multi-Pronged Approach to Measuring Endothelial Dysfunction and Predict the Development of Endothelial Disorders and Death Post Hematopoietic Cell Transplantation (HCT)

Free
Michelle L Schoettler, Ritu Sachdeva, Muna Qayed, Benjamin Watkins, Suhag Parikh, Kathryn Leung, Elizabeth O Stenger, Ann Haight, Katherine Silvis, Yvonne Suessmuth, Adrianna Westbrook, Kirsten M. Williams
Journal: Blood
Blood (2024) 144 (Supplement 1): 4888.
https://doi.org/10.1182/blood-2024-208492
Published: 2024
Journal Articles

Abatacept for acute graft-versus-host disease prophylaxis after unrelated donor hematopoietic cell transplantation

Free
Clinical Trials & Observations
Leslie S. Kean, Linda J. Burns, Tzuyung D. Kou, Roxanne Kapikian, Karissa Lozenski, Amelia Langston, John T. Horan, Benjamin Watkins, Muna Qayed, Brandi Bratrude, Kayla Betz, Xiao-Ying Tang, Mei-Jie Zhang, Sean E. Connolly, Martin Polinsky, Brian Gavin, Andres Gomez-Caminero, Marcelo C. Pasquini
Journal: Blood
Blood (2024) 144 (17): 1834–1845.
https://doi.org/10.1182/blood.2023023660
Published: 2024
Includes: Supplemental data
Journal Articles

Novel MAGIC composite scores using both clinical symptoms and biomarkers best predict treatment outcomes of acute GVHD

Free
Clinical Trials & Observations
Yu Akahoshi, Nikolaos Spyrou, Daniela Weber, Paibel Aguayo-Hiraldo, Francis Ayuk, Chantiya Chanswangphuwana, Hannah K. Choe, Matthias Eder, Aaron M. Etra, Stephan A. Grupp, Elizabeth O. Hexner, William J. Hogan, Carrie L. Kitko, Sabrina Kraus, Monzr M. Al Malki, Pietro Merli, Muna Qayed, Ran Reshef, Tal Schechter, Evelyn Ullrich, Ingrid Vasova, Matthias Wölfl, Robert Zeiser, Janna Baez, Rahnuma Beheshti, Gilbert Eng, Sigrun Gleich, Nikolaos Katsivelos, Steven Kowalyk, George Morales, Rachel Young, Yi-Bin Chen, Ryotaro Nakamura, John E. Levine, James L. M. Ferrara
Journal: Blood
Blood (2024) 144 (9): 1010–1021.
https://doi.org/10.1182/blood.2024025106
Published: 2024
Includes: Supplemental data
Journal Articles

Age, Gvhd Prophylaxis, and Timing Matter in Thrombotic Microangiopathy after Hematopoietic Cell Therapy- a Secondary CIBMTR Analysis

Free
Michelle L Schoettler, Benjamin Watkins, Muna Qayed, Satheesh Chonat, Adrianna Westbrook, Kirsten M Williams
Journal: Blood
Blood (2023) 142 (Supplement 1): 2153.
https://doi.org/10.1182/blood-2023-174752
Published: 2023