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Journal Articles

Effective treatment with the selective cytokine inhibitor BNZ-1 reveals the cytokine dependency of T-LGL leukemia

Jonathan E. Brammer, Karen Ballen, Lubomir Sokol, Christiane Querfeld, Ryotaro Nakamura, Anjali Mishra, Eric M. McLaughlin, David Feith, Nazli Azimi, Thomas A. Waldmann, Yutaka Tagaya, Thomas Loughran

Blood (2023) 142 (15): 1271–1280.

https://doi.org/10.1182/blood.2022017643

Published: 2023

Includes: Supplemental data

Journal Articles

Blockade of IL-15 Utilizing Bnz-1, a Selective γ-Chain Inhibiting Peptide, Is Safe and Has Clinical Activity in Patients with T-Cell Large Granular Lymphocytic Leukemia (T-LGLL): Results of a Phase I/II Multi-Center Clinical Trial

Jonathan E. Brammer, MD, Lubomir Sokol, MD PhD, Yutaka Tagaya, MD PhD, Kerry Rogers, Anjali Mishra, PhD, Thomas A. Waldmann, MD, Nazli Azimi, PhD PharmD, Paul Frohna, MD PhD PharmD, Anoshie Ratnayake, MD, Thomas P Loughran, Jr., MD, Karen Ballen, MD

Blood (2019) 134 (Supplement_1): 2835.

https://doi.org/10.1182/blood-2019-129291

Published: 2019

Journal Articles

Phase I Study of Bortezomib Combined with Lenalidomide for Relapsed Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) Following Hematopoietic Cell Transplantation

Andrew M. Brunner, MD, Traci M. Blonquist, MS, Malgorzata McMasters, MD, Gabriela S. Hobbs, MD, Steven L McAfee, MD, Jacalyn Rosenblatt, MD, Philip C. Amrein, MD, Areej El-Jawahri, MD, Christine Connolly, Aura Ramos, Kaleb Mikami, Emma Logan, Bimalangshu R Dey, MD PhD, Thomas Spitzer, MD, David E. Avigan, MD, Amir T. Fathi, MD MD BS, Yi-Bin Chen, MD, Karen Ballen, MD

Blood (2017) 130 (Supplement 1): 3280.

https://doi.org/10.1182/blood.V130.Suppl_1.3280.3280

Published: 2017

Journal Articles

Assessment of a Multi-Cytokine Profile By a Novel Biochip-Based Assay Reveals Unique Correlation Patterns with Immune Reconstitution after Cord Blood Transplantation in Adults

Theodoros Karantanos, MD, Haesook T Kim, PhD, Lequn Li, MD PhD, Corey Cutler, MD MPH, FRCPC, Joseph H. Antin, MD, Karen Ballen, MD, Jerome Ritz, MD, Ioannis Politikos, MD, Vassiliki A Boussiotis, MD PhD

Blood (2017) 130 (Supplement 1): 1980.

https://doi.org/10.1182/blood.V130.Suppl_1.1980.1980

Published: 2017

Journal Articles

Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation

Blood (2013) 122 (17): 3074–3081.

https://doi.org/10.1182/blood-2013-05-503177

Published: 2013

Includes: Supplemental data

Journal Articles

Donor-specific anti-HLA antibodies predict outcome in double umbilical cord blood transplantation

Corey Cutler, Haesook T. Kim, Lixian Sun, Doreen Sese, Brett Glotzbecker, Philippe Armand, John Koreth, Vincent Ho, Edwin Alyea, Karen Ballen, Jerome Ritz, Robert J. Soiffer, Edgar Milford, Joseph H. Antin

Blood (2011) 118 (25): 6691–6697.

https://doi.org/10.1182/blood-2011-05-355263

Published: 2011

Journal Articles

Clearance of CMV viremia and survival after double umbilical cord blood transplantation in adults depends on reconstitution of thymopoiesis

Blood (2010) 115 (20): 4111–4119.

https://doi.org/10.1182/blood-2009-09-244145

Published: 2010

Includes: Supplemental data

Journal Articles

Reducing the Risk for Transplant Related Mortality After Allogeneic Hematopoietic Cell Transplantation: How Much Progress Has Been Made?.

John Horan, MD, MPH, Brent R. Logan, PhD, Manza-A. Agovi, MPH, Hillard M Lazarus, MD, Andrea Bacigalupo, MD, Karen Ballen, Rodrigo Martino, Mark B. Juckett, MD, Hanna J. Khoury, MD, Christopher Bredeson, MD, Vikas Gupta, Franklin O. Smith, MD, Gregory Hale, Matthew Carabasi, MD, Philip L. McCarthy, MD, J. Douglas Rizzo, MD, MS, Marcelo C. Pasquini, MD

Blood (2009) 114 (22): 649.

https://doi.org/10.1182/blood.V114.22.649.649

Published: 2009

Journal Articles

Long Term Follow-up of Recipients of Combined HLA-Matched Nonmyeloablative Bone Marrow and Kidney Transplantation for Multiple Myeloma with End-Stage Renal Disease.

Thomas R Spitzer, MD, Megan Sykes, MD, Nina Tolkoff Rubin, MD, Tatsuo Kawai, MD, Steven L McAfee, MD, Bimalangshu Dey, MD, PhD, Karen Ballen, MD, Francis Delmonico, MD, Susan Saidman, PhD, David H Sachs, M.D., Benedict Cosimi, MD

Blood (2009) 114 (22): 3368.

https://doi.org/10.1182/blood.V114.22.3368.3368

Published: 2009

Journal Articles

Double Umbilical Cord Blood Transplantation with Reduced Intensity Conditioning and Sirolimus-Based GVHD Prophylaxis.

Corey Cutler, MD, MPH, FRCPC, Rachel Mitrovich, Grace Kao, MD, Vincent Ho, MD, Edwin Alyea, MD, John Koreth, MBBS, Philippe Armand, MD, Bimalangshu Dey, MD, Thomas Spitzer, MD, Robert Soiffer, MD, Joseph H. Antin, MD, Karen Ballen, MD

Blood (2007) 110 (11): 2016.

https://doi.org/10.1182/blood.V110.11.2016.2016

Published: 2007

Journal Articles

An International Multi-Institutional Study of Double Cord Blood Transplantation in a Racially Diverse Population.

Karen Ballen, Brian Wang, Joseph Rosenthal, Auayporn Nademanee, Chatchada Karanes, Tang-Her Jaing, Michael Graham, Patrick Tan, David Gjertson, Lawrence Petz, Stephen Forman, Robert Chow

Blood (2007) 110 (11): 2017.

https://doi.org/10.1182/blood.V110.11.2017.2017

Published: 2007

Journal Articles

Cardiac Transplant Followed by High-Dose Melphalan and Autologous Stem Cell Transplantation (ASCT) for Patients with AL Amyloidosis and Severe Heart Failure.

Bimalangshu R. Dey, MD, PhD, Thomas R. Spitzer, MD, Thomas E. MacGillivray, MD, Stephen S. Chung, MD, G.W. Dec, MD, David C. Seldin, MD, Steven L. McAfee, MD, Karen Ballen, MD, Eyal Attar, MD, Martha Skinner, MD, Joren C. Madsen, MD, DPhil, Marc J. Semigran, MD

Blood (2007) 110 (11): 732.

https://doi.org/10.1182/blood.V110.11.732.732

Published: 2007

Journal Articles

Impact of Ethnicity and Socioeconomic Status on Outcome of Unrelated Donor (URD) Hematopoietic Cell Transplantation (HcT).

K. Scott Baker, MD, MS, Anna Hassebroek, MPH, Karen Ballen, MD, Carolyn Bigelow, MD, Haydar Frangoul, MD, Cheryl Hardy, PhD, Stephanie Lee, MD,MPH, Galen Switzer, PhD, J. Douglas Rizzo, MD, John P. Klein, PhD, Navneet Majhail, MD,MS, Stella Davies, MB.BS,PhD

Blood (2007) 110 (11): 3064.

https://doi.org/10.1182/blood.V110.11.3064.3064

Published: 2007

Journal Articles

The Type of Upfront Induction Therapy for Newly Diagnosed Multiple Myeloma Patients Has No Significant Impact on Clinical Outcomes after Autologous Hematopoietic Stem Cell Transplantation.

Stephen S. Chung, MD, Thomas R. Spitzer, MD, David T. Ting, MD, Christine Dube, Andrew J. Yee, MD, Karen Ballen, MD, Steven L. McAfee, MD, Eyal Attar, MD, Bimalangshu R. Dey, MD, PhD

Blood (2007) 110 (11): 5128.

https://doi.org/10.1182/blood.V110.11.5128.5128

Published: 2007

Journal Articles

Non-Myeloablative T-Cell Depleted (TCD) Haploidentical Hematopoietic Cell Transplantation (HCT) Followed by Donor Leukocyte Infusion(s) for Hematologic Malignancies: The MGH Experience.

Bimalangshu R. Dey, MD, PhD, Andrew J. Yee, MD, Steven McAfee, MD, Christine Dube, Karen Ballen, MD, Eyal Attar, MD, Christine Colby, Susan Saidman, PhD, Karen Malikowski, Frederic Preffer, PhD, Megan Sykes, MD, Thomas R. Spitzer, MD

Blood (2007) 110 (11): 5088.

https://doi.org/10.1182/blood.V110.11.5088.5088

Published: 2007

Journal Articles

A Phase II Study of Dasatinib in Relapsed and Refractory Chronic Lymphocytic Leukemia (CLL/SLL).

Philip C. Amrein, MD, Eyal C. Attar, M.D., Tak Takvorian, M.D., Ephraim P. Hochberg, M.D., Karen Ballen, M.D., David Zahrieh, M.S., Jennifer R. Brown, M.D.

Blood (2007) 110 (11): 3126.

https://doi.org/10.1182/blood.V110.11.3126.3126

Published: 2007

Journal Articles

Impaired Immune Reconstitution after Cord Blood Transplantation in Adults Is Associated with Delayed Recovery but Not Functional Impairment of CD8 + T Cells.

Julia Brown, PhD, Karen Ballen, MD, Sean McDonough, Xupeng Ge, MD, PhD, Kristen Stevenson, PhD, Haesook Kim, PhD, Carol Reynolds, Bimalangshu R. Dey, MD, PhD, Steve McAfee, MD, Eyal Attar, MD, Thomas Spitzer, MD, Corey Cutler, MD, Vincent Ho, MD, Edwin Alyea, MD, Robert Soiffer, MD, Joseph H. Antin, MD, Jerome Ritz, MD, Vassiliki A. Boussiotis, MD, PhD

Blood (2007) 110 (11): 1057.

https://doi.org/10.1182/blood.V110.11.1057.1057

Published: 2007

Journal Articles

Effects of Cord Blood Cell Subset Populations in the Development of the Dominant Cord Blood Unit in Non-Myeloablative Sequential Double Cord Blood Transplantation (DCBT).

David T. Ting, MD, Karen Ballen, MD, Thomas R. Spitzer, MD, Richard L. Haspel, MD, Michelle Dorn, Fred Preffer, PhD, Vassiliki Boussiotis, MD PhD, Steven McAfee, MD, Eyal Attar, MD, Joseph H. Antin, MD, Robert J. Soiffer, MD, Corey Cutler, MD MPH, Vincent Ho, MD, Bimalangshu R. Dey, MD

Blood (2006) 108 (11): 3148.

https://doi.org/10.1182/blood.V108.11.3148.3148

Published: 2006

Journal Articles

Fludarabine Treatment Is Associated with Depletion of Host CD4+CD25 high , FOXP3+, CTLA-4+ Cells and Increased Incidences of Full Donor Chimerism and GVHD in Non-Myeloablative Haploidentical Hematopoietic Cell Transplant Recipients.

Juanita M. Shaffer, Jean Villard, Terry Means, David Dombkowski, Bimalangshu Dey, Steven McAffee, Karen Ballen, Karen Power, Susan Saidman, Fredric Preffer, Thomas R. Spitzer, Megan Sykes

Blood (2005) 106 (11): 2898.

https://doi.org/10.1182/blood.V106.11.2898.2898

Published: 2005

Journal Articles

Pre-Infusion Characteristics of the Predominant Cord Blood Unit Correlate with Hematopoietic Engraftment in the Setting of Non-Myeloablative Double Cord Blood Transplant (DCBT).

Richard L. Haspel, MD, PhD, Grace S. Kao, MD, Beow Yeap, SC.D, Thomas R. Spitzer, MD, Jerome Ritz, MD, Joseph H. Antin, MD, Karen Ballen, MD

Blood (2005) 106 (11): 3027.

https://doi.org/10.1182/blood.V106.11.3027.3027

Published: 2005

NARROW

Effective treatment with the selective cytokine inhibitor BNZ-1 reveals the cytokine dependency of T-LGL leukemia

Blockade of IL-15 Utilizing Bnz-1, a Selective γ-Chain Inhibiting Peptide, Is Safe and Has Clinical Activity in Patients with T-Cell Large Granular Lymphocytic Leukemia (T-LGLL): Results of a Phase I/II Multi-Center Clinical Trial

Phase I Study of Bortezomib Combined with Lenalidomide for Relapsed Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS) Following Hematopoietic Cell Transplantation

Assessment of a Multi-Cytokine Profile By a Novel Biochip-Based Assay Reveals Unique Correlation Patterns with Immune Reconstitution after Cord Blood Transplantation in Adults

Prostaglandin-modulated umbilical cord blood hematopoietic stem cell transplantation

Donor-specific anti-HLA antibodies predict outcome in double umbilical cord blood transplantation

Clearance of CMV viremia and survival after double umbilical cord blood transplantation in adults depends on reconstitution of thymopoiesis

Reducing the Risk for Transplant Related Mortality After Allogeneic Hematopoietic Cell Transplantation: How Much Progress Has Been Made?.

Long Term Follow-up of Recipients of Combined HLA-Matched Nonmyeloablative Bone Marrow and Kidney Transplantation for Multiple Myeloma with End-Stage Renal Disease.

Double Umbilical Cord Blood Transplantation with Reduced Intensity Conditioning and Sirolimus-Based GVHD Prophylaxis.

An International Multi-Institutional Study of Double Cord Blood Transplantation in a Racially Diverse Population.

Cardiac Transplant Followed by High-Dose Melphalan and Autologous Stem Cell Transplantation (ASCT) for Patients with AL Amyloidosis and Severe Heart Failure.

Impact of Ethnicity and Socioeconomic Status on Outcome of Unrelated Donor (URD) Hematopoietic Cell Transplantation (HcT).

The Type of Upfront Induction Therapy for Newly Diagnosed Multiple Myeloma Patients Has No Significant Impact on Clinical Outcomes after Autologous Hematopoietic Stem Cell Transplantation.

Non-Myeloablative T-Cell Depleted (TCD) Haploidentical Hematopoietic Cell Transplantation (HCT) Followed by Donor Leukocyte Infusion(s) for Hematologic Malignancies: The MGH Experience.

A Phase II Study of Dasatinib in Relapsed and Refractory Chronic Lymphocytic Leukemia (CLL/SLL).

Impaired Immune Reconstitution after Cord Blood Transplantation in Adults Is Associated with Delayed Recovery but Not Functional Impairment of CD8 + T Cells.

Effects of Cord Blood Cell Subset Populations in the Development of the Dominant Cord Blood Unit in Non-Myeloablative Sequential Double Cord Blood Transplantation (DCBT).

Fludarabine Treatment Is Associated with Depletion of Host CD4+CD25 high , FOXP3+, CTLA-4+ Cells and Increased Incidences of Full Donor Chimerism and GVHD in Non-Myeloablative Haploidentical Hematopoietic Cell Transplant Recipients.

Pre-Infusion Characteristics of the Predominant Cord Blood Unit Correlate with Hematopoietic Engraftment in the Setting of Non-Myeloablative Double Cord Blood Transplant (DCBT).

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American Society of Hematology

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American Society of Hematology

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