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Journal Articles

Description of an Adolescent and Young Adult Sickle Cell Transition Program: Using Clinical Practices to Inform Clinic Development

Sarah Smith, Jessica O'Brien, Barbara Mclain, Suzanne Braniecki, Edo Schaefer, Lila Pereira
Journal: Blood
Blood (2024) 144 (Supplement 1): 7537.
https://doi.org/10.1182/blood-2024-211923
Published: 2024
Journal Articles

Addressing Patient Representation in Hematopoietic Cell Transplant Clinical Trials: Insights Gained through the Access Trial

Jeffery J. Auletta, Stephanie Bo-Subait, Abeer Madbouly, Jaime M. Preussler, Janelle Olson, Lindsay Bankole, Sarah Smith, Martin J. Maiers, Yung-Tsi Bolon, Jennifer Novakovich, Kelly Buck, Craig Malmberg, Kim Wadsworth, Stephanie Fingerson, Christa L Meyer, Anna M. DeSalvo, Katie Schoeppner, Jackie Foster, Ben Tweeten, Rachel Cusatis, Deborah Mattila, Caitrin Bupp, Juan Wu, Larisa Broglie, Brent R. Logan, Bronwen E. Shaw, Heather E. Stefanski, Stephen R. Spellman, Steven M. Devine
Journal: Blood
Blood (2024) 144 (Supplement 1): 3672.
https://doi.org/10.1182/blood-2024-198523
Published: 2024
Journal Articles

Characterization of Multicellular Niches Supporting Hematopoietic Stem Cells within Distinct Zones

Ruochen Dong, Hua Li, Xi He, Chen Wang, Anoja Perera, Seth Malloy, Jonathon Russell, Wenting Li, Kaitlyn Petentler, Xinjian Mao, Zhe Yang, Michael Epp, Kate Hall, Allison Scott, Mary C McKinney, Shengping Huang, Sarah Smith, Mark Hembree, Yongfu Wang, Zulin Yu, Jeff Haug, Jay Unruh, Brian Slaughter, Xunlei Kang, Linheng Li
Journal: Blood
Blood (2024) 144 (Supplement 1): 1306.
https://doi.org/10.1182/blood-2024-208450
Published: 2024
Journal Articles

Non-Genotoxic Conditioning for Hematopoietic Stem Cell Transplant through Engineered Stem Cell Antibody Paired Evasion (ESCAPE)

Nandini Mondal, Alexander Harmon, Elizabeth Budak, Kathy Zhang, Jeffrey Wong, Archita Venugopal Menon, Adam Wolin, Moriah White, Faith Musenge, Adam Camblin, Brent Coisman, Corrina Lucini, Tao Bai, Kangjian Qiao, Wayne Austin, Michelle DeLelys, Hugh Kromer, Lisa Hardy, Megan Law, Raffi Manoukian, Rachel Goldsmith, Kiera Fallon, Mudra Patel, Antoinette Cozier, Colin Lazzara, Jeremy Decker, Rebecca Jenkins, Tanggis Bohnuud, Patricia Feliciano, Seung-Joo Lee, Paul Kopesky, Sarah Smith, Charlotte McDonagh, Nicole Gaudelli, S. Haihua Chu, Adam Hartigan, Gopi Shankar, Giuseppe Ciaramella
Journal: Blood
Blood (2023) 142 (Supplement 1): 7128.
https://doi.org/10.1182/blood-2023-182077
Published: 2023
Journal Articles

Spatial Transcriptomics Reveals Distinct Hematopoietic Stem Cell Niches in Mouse Fetal Liver

Ruochen Dong, Hua Li, Xi He, Anoja Perera, Seth Malloy, Jonathon Russell, Wenting Li, Kaitlyn Petentler, Xinjian Mao, Zhe Yang, Michael Epp, Kate Hall, Allison Scott, Sarah Smith, Mark Hembree, Yongfu Wang, Sean McKinney, Jeff Haug, Jay Unruh, Brian Slaughter, Linheng Li
Journal: Blood
Blood (2023) 142 (Supplement 1): 2700.
https://doi.org/10.1182/blood-2023-189880
Published: 2023
Journal Articles

Engineered Stem Cell Antibody Paired Evasion 1 (ESCAPE-1): Paired HSC Epitope Engineering and Upregulation of Fetal Hemoglobin for Antibody-Mediated Autologous Hematopoietic Stem Cell Therapy Conditioning for the Treatment of Hemoglobinopathies

Nandini Mondal, Alexander Harmon, Elizabeth Budak, Kathy Zhang, Jeffrey Wong, Conrad Rinaldi, Jenny Olins, Kara Hoar, Archita Venugopal Menon, Moriah White, Faith Musenge, Adam Camblin, Adam Wolin, Brent Coisman, Tao Bai, Kangjian Qiao, Mudra Patel, Jeremy Decker, Bob Gantzer, Thomas Leete, Yi Yu, Tanggis Bohnuud, Seung-Joo Lee, Sarah Smith, Charlotte F McDonagh, Nicole M. Gaudelli, S. Haihua Chu, Adam J. Hartigan, Giuseppe Ciaramella
Journal: Blood
Blood (2022) 140 (Supplement 1): 4487–4488.
https://doi.org/10.1182/blood-2022-169120
Published: 2022
Journal Articles

Conversion of HbS to Hb G-Makassar By Adenine Base Editing Is Compatible with Normal Hemoglobin Function

S. Haihua Chu, Manuel Ortega, Paty Feliciano, Valerie Winton, Chavonna Xu, Daniel Haupt, Teresa McDonald, Salette Martinez, Alexander Liquori, Jeffrey Marshall, Daisy Lam, Jenny Olins, Conrad Rinaldi, Kyle Rehberger, Colin Lazarra, Jeremy Decker, Bob Gantzer, Tanggis Bohnuud, David Born, Luis Barrera, Bo Yan, Ian Slaymaker, Michael S. Packer, Sarah Smith, Carlo Zambonelli, Matt Lee, Nicole M. Gaudelli, Adam J. Hartigan, Giuseppe Ciaramella
Journal: Blood
Blood (2021) 138 (Supplement 1): 951.
https://doi.org/10.1182/blood-2021-150922
Published: 2021
Journal Articles

Indirect Treatment Comparisons of the Effect of Fedratinib Versus Navitoclax Plus Ruxolitinib on Spleen Volume and Symptoms in Patients with Myelofibrosis and Prior Ruxolitinib Treatment

Pranav Abraham, Xiaomeng Liao, Manoj Chevli, Sarah Smith
Journal: Blood
Blood (2021) 138 (Supplement 1): 4626.
https://doi.org/10.1182/blood-2021-145862
Published: 2021
Journal Articles

Highly Efficient Multiplexed Base Editing with Minimized Off-Targets for the Development of Universal CAR-T Cells to Treat Pediatric T-ALL

Jason M Gehrke, PhD, Aaron Edwards, MS, Ryan C. Murray, MS, Amy Shaw, MS, Yeh-Chuin Poh, PhD, Sarah Smith, Yi Yu, PhD, Nicole M. Gaudelli, PhD, Waseem Qasim, MBBS, PhD, Giuseppe Ciaramella, PhD, B.Sc.
Journal: Blood
Blood (2019) 134 (Supplement_1): 5127.
https://doi.org/10.1182/blood-2019-130562
Published: 2019
Journal Articles

Complementary Base Editing Approaches for the Treatment of Sickle Cell Disease and Beta Thalassemia

Ling Lin, PhD, Adrian P. Rybak, PhD, Conrad Rinaldi, M.S., Jonathan Yen, PhD, Yanfang Fu, PhD, Elsie Akrawi, Sarah Smith, Scott J. Haskett, M.S., Minerva E. Sanchez, Yeh-Chuin Poh, PhD, Michael S. Packer, PhD, Nicole M. Gaudelli, PhD, Manmohan Singh, PhD, Giuseppe Ciaramella, PhD, B.Sc., Dana N. Levasseur, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3352.
https://doi.org/10.1182/blood-2019-126710
Published: 2019
Journal Articles

Genome Editing of the Bcl11A Erythroid Specific Enhancer in Bone Marrow Derived Hematopoietic Stem and Progenitor Cells for the Treatment of Sickle Cell Disease

Siyuan Tan, PhD, Kai-Hsin Chang, PhD, Sarah Smith, BS, Kai Chen, MS, Timonthy Sullivan, BS, Qianhe Zhou, PhD, Andreas Reik, PhD, Fyodor D Urnov, PhD, Edward J. Rebar, PhD, Olivier Danos, PhD, Haiyan Jiang, PhD
Journal: Blood
Blood (2015) 126 (23): 203.
https://doi.org/10.1182/blood.V126.23.203.203
Published: 2015
Journal Articles

Clonal Analysis of Human Bone Marrow CD34+ Cells Edited By BCL11A-Targeting Zinc Finger Nucleases Reveals Clinically Relevant Levels of Fetal Globin Expression in Edited Erythroid Progeny

Kai-Hsin Chang, PhD, Timothy Sullivan, MS, Mei Liu, BS, Xiao Yang, PhD, Chao Sun, PhD, Benjamin Vieira, BS, Ming Zhang, PhD, Vu P. Hong, PhD, Kai Chen, MS, Sarah Smith, BS, Siyuan Tan, PhD, Andreas Reik, PhD, Fyodor D Urnov, PhD, Edward J. Rebar, PhD, Olivier Danos, PhD, Haiyan Jiang, PhD
Journal: Blood
Blood (2015) 126 (23): 3234.
https://doi.org/10.1182/blood.V126.23.3234.3234
Published: 2015
Journal Articles

Enhancing the Acute Hemostatic Efficacy in Cynomolgus Monkeys By Targeting Activated Coagulation Factor VII to Platelets

Siyuan Tan, PhD, Joe Salas, PhD, Kai Chen, Tamera Ashworth, Sarah Smith, Elena Kistanova, Nancy Moore, Marisol Acosta, Anxhela Kole, David R. Light, PhD, Robert Peters, PhD, Haiyan Jiang, PhD
Journal: Blood
Blood (2014) 124 (21): 1488.
https://doi.org/10.1182/blood.V124.21.1488.1488
Published: 2014