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Journal Articles

BIVV001, a new class of factor VIII replacement for hemophilia A that is independent of von Willebrand factor in primates and mice

Ekta Seth Chhabra, Tongyao Liu, John Kulman, Susannah Patarroyo-White, Buyue Yang, Qi Lu, Douglas Drager, Nancy Moore, Jiayun Liu, Amy M. Holthaus, Jurg M. Sommer, Ayman Ismail, Deana Rabinovich, Zhan Liu, Arjan van der Flier, Allison Goodman, Chris Furcht, Mark Tie, Tyler Carlage, Randy Mauldin, Terrence M. Dobrowsky, Zhiqian Liu, Oblaise Mercury, Lily Zhu, Baisong Mei, Volker Schellenberger, Haiyan Jiang, Glenn F. Pierce, Joe Salas, Robert Peters
Journal: Blood
Blood (2020) 135 (17): 1484–1496.
https://doi.org/10.1182/blood.2019001292
Published: 2020
Includes: Supplemental data
Journal Articles

Genetic Activation of NRF2 By KEAP1 Inhibition Induces Fetal Hemoglobin Expression and Triggers Anti-Oxidant Stress Response in Erythroid Cells

Dipti Gupta, Samuel Lessard, PhD, Nancy Moore, Jicheng Duan, PhD, Yukio Nakamura, MD PhD, Feng-Chun Yang, MD PhD, Alexandra Hicks, PhD, David R. Light, PhD, Sriram Krishnamoorthy, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 210.
https://doi.org/10.1182/blood-2019-129479
Published: 2019
Journal Articles

Evaluation of Enhanced in Vitro Plasma Stability of a Novel Long Acting Recombinant FVIIIFc-VWF-XTEN Fusion Protein

Ekta Seth Chhabra, PhD, Nancy Moore, Chris Furcht, Amy M Holthaus, BS, MS, Jiayun Liu, MS, Tongyao Liu, Volker Schellenberger, PhD, John Kulman, PhD, Joe Salas, PhD, Robert Peters, PhD
Journal: Blood
Blood (2015) 126 (23): 2279.
https://doi.org/10.1182/blood.V126.23.2279.2279
Published: 2015
Journal Articles

Novel Approach to Study Biodistribution and Accumulation of Pegylated Recombinant Factor VIII in Haemophilia A Mice

Vu P. Hong, PhD, Ayman Ismail, PhD, Nancy Moore, Robert Peters, PhD, Joe Salas, PhD
Journal: Blood
Blood (2015) 126 (23): 3517.
https://doi.org/10.1182/blood.V126.23.3517.3517
Published: 2015
Journal Articles

Platelet-Targeted rFVIIa-Xten Improves Thrombin Generation and Fibrin Formation Compared to Recombinant FVIIa

Maria M. Aleman, PhD, Elena N. Kistanova, Nancy Moore, Volker Schellenberger, PhD, Robert Peters, PhD, Joe Salas, PhD
Journal: Blood
Blood (2015) 126 (23): 2269.
https://doi.org/10.1182/blood.V126.23.2269.2269
Published: 2015
Journal Articles

Enhancing the Acute Hemostatic Efficacy in Cynomolgus Monkeys By Targeting Activated Coagulation Factor VII to Platelets

Siyuan Tan, PhD, Joe Salas, PhD, Kai Chen, Tamera Ashworth, Sarah Smith, Elena Kistanova, Nancy Moore, Marisol Acosta, Anxhela Kole, David R. Light, PhD, Robert Peters, PhD, Haiyan Jiang, PhD
Journal: Blood
Blood (2014) 124 (21): 1488.
https://doi.org/10.1182/blood.V124.21.1488.1488
Published: 2014