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Ekta Seth Chhabra
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Journal Articles

Mechanistic Modeling to Support Hemostatic Equivalency of Antithrombin Lowering in People with Hemophilia A or B

Randolph Leiser, Chanchala Kaddi, Mengdi Tao, Ane Salvador, Ekta Seth Chhabra, Susana Zaph
Journal: Blood
Blood (2024) 144 (Supplement 1): 2590.
https://doi.org/10.1182/blood-2024-199185
Published: 2024
Journal Articles

Development of a Quantitative Systems Pharmacology Model to Explore Hemostatic Equivalency of Antithrombin Lowering

Chanchala Kaddi, Mengdi Tao, Randolph Leiser, Ane Salvador, Sravya Kattula, Pratik Bhagunde, Viridiana Cano Garcia, Ekta Seth Chhabra, Susana Zaph
Journal: Blood
Blood (2022) 140 (Supplement 1): 5606–5607.
https://doi.org/10.1182/blood-2022-169043
Published: 2022
Journal Articles

Efanesoctocog Alfa Half-Life and Clearance Are Independent of von Willebrand Factor in Severe Hemophilia A: A Post Hoc Analysis from Phase 1/2a Studies

Janice M. Staber, Toshko Lissitchkov, Barbara A. Konkle, Amy D. Shapiro, Doris V. Quon, Roshni Kulkarni, Melinda Hamilton, Ekta Seth Chhabra, Suresh Katragadda, Arman Altincatal, Annemieke Willemze, Jennifer Dumont, Margaret V. Ragni
Journal: Blood
Blood (2021) 138 (Supplement 1): 1035.
https://doi.org/10.1182/blood-2021-148534
Published: 2021
Journal Articles

BIVV001, a new class of factor VIII replacement for hemophilia A that is independent of von Willebrand factor in primates and mice

Ekta Seth Chhabra, Tongyao Liu, John Kulman, Susannah Patarroyo-White, Buyue Yang, Qi Lu, Douglas Drager, Nancy Moore, Jiayun Liu, Amy M. Holthaus, Jurg M. Sommer, Ayman Ismail, Deana Rabinovich, Zhan Liu, Arjan van der Flier, Allison Goodman, Chris Furcht, Mark Tie, Tyler Carlage, Randy Mauldin, Terrence M. Dobrowsky, Zhiqian Liu, Oblaise Mercury, Lily Zhu, Baisong Mei, Volker Schellenberger, Haiyan Jiang, Glenn F. Pierce, Joe Salas, Robert Peters
Journal: Blood
Blood (2020) 135 (17): 1484–1496.
https://doi.org/10.1182/blood.2019001292
Published: 2020
Includes: Supplemental data
Journal Articles

The von Willebrand factor D′D3 assembly and structural principles for factor VIII binding and concatemer biogenesis

Xianchi Dong, Nina C. Leksa, Ekta Seth Chhabra, Joseph W. Arndt, Qi Lu, Kevin E. Knockenhauer, Robert T. Peters, Timothy A. Springer
Journal: Blood
Blood (2019) 133 (14): 1523–1533.
https://doi.org/10.1182/blood-2018-10-876300
Published: 2019
Includes: Multimedia, Supplemental data
Journal Articles

Evaluation of Enhanced in Vitro Plasma Stability of a Novel Long Acting Recombinant FVIIIFc-VWF-XTEN Fusion Protein

Ekta Seth Chhabra, PhD, Nancy Moore, Chris Furcht, Amy M Holthaus, BS, MS, Jiayun Liu, MS, Tongyao Liu, Volker Schellenberger, PhD, John Kulman, PhD, Joe Salas, PhD, Robert Peters, PhD
Journal: Blood
Blood (2015) 126 (23): 2279.
https://doi.org/10.1182/blood.V126.23.2279.2279
Published: 2015
Journal Articles

Prolonged Half-Life and Improved Recovery of Recombinant Factor IX-XTEN Fusion Proteins in Hemophilia B Mouse Model

Arjan van der Flier, PhD, Zhiqian Lucy Liu, PhD, Zhan Liu, MSc, Oblaise Mercury, BS, Ayman Ismail, PhD, Ekta Seth-Chhabra, PhD, John Kulman, PhD, Volker Schellenberger, PhD, David R. Light, PhD, Robert Peters, PhD
Journal: Blood
Blood (2015) 126 (23): 2271.
https://doi.org/10.1182/blood.V126.23.2271.2271
Published: 2015
Journal Articles

Mapping the interaction between factor VIII and von Willebrand factor by electron microscopy and mass spectrometry

Brief Report
Po-Lin Chiu, George M. Bou-Assaf, Ekta Seth Chhabra, Melissa G. Chambers, Robert T. Peters, John D. Kulman, Thomas Walz
Journal: Blood
Blood (2015) 126 (8): 935–938.
https://doi.org/10.1182/blood-2015-04-641688
Published: 2015
Includes: Multimedia, Supplemental data
Journal Articles

The Effect of Factor IXa on Thrombin Generation Activity Determination: rFIXFc Vs. BeneFIX ®

Yang Buyue, PhD, Ekta Seth Chhabra, PhD, Li Wang, Jurg M Sommer, PhD
Journal: Blood
Blood (2011) 118 (21): 2266.
https://doi.org/10.1182/blood.V118.21.2266.2266
Published: 2011