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Joe Salas
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Journal Articles

Single Dose of Tgroβ (EN-145)/Plerixafor Safely and Effectively Mobilizes Primitive HSCs in Mouse Models for In Vivo Gene Therapy of Sickle Cell Disease

Courtney Mercadante, Vemika Chandra, Miriama Kruta Vincent, Herika Fernandez, Jinpeng Wang, Brian Zifcak, Kayla Frank, Robert T. Peters, Joe Salas, Pauline Rimmele
Journal: Blood
Blood (2024) 144 (Supplement 1): 4770.
https://doi.org/10.1182/blood-2024-208459
Published: 2024
Journal Articles

In Vivo Hematopoietic Stem Cell Engineering Restores the Function of NADPH Enzyme Complex in X-Linked Chronic Granulomatous Disease Model Mice

Sravya Kattula, Gaurav M. Rajani, Vemika Chandra, Mike M. Martinez, Raissa Eluere, Patrick Au, Robert T. Peters, Joe Salas
Journal: Blood
Blood (2024) 144 (Supplement 1): 2198.
https://doi.org/10.1182/blood-2024-203662
Published: 2024
Journal Articles

Mechanistic Studies of Thrombin Generation Assay to Evaluate Procoagulant Potential of Fitusiran

Sravya Kattula, PhD, Ane Salvador, PhD, Shaobin Wang, PhD, Ayman Ismail, PhD, Arjan van der Flier, PhD, Nina Leksa, PhD, Joe Salas, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 6.
https://doi.org/10.1182/blood-2020-142760
Published: 2020
Journal Articles

Reducing Antithrombin in Plasma to Levels Observed in Fitusiran-Treated Patients Does Not Interfere with Coagulation Assays

Shaobin Wang, PhD, Sravya Kattula, PhD, Ayman Ismail, PhD, Nina Leksa, PhD, Arjan van Der Flier, PhD, Joe Salas, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10.
https://doi.org/10.1182/blood-2020-142724
Published: 2020
Journal Articles

BIVV001, a new class of factor VIII replacement for hemophilia A that is independent of von Willebrand factor in primates and mice

Ekta Seth Chhabra, Tongyao Liu, John Kulman, Susannah Patarroyo-White, Buyue Yang, Qi Lu, Douglas Drager, Nancy Moore, Jiayun Liu, Amy M. Holthaus, Jurg M. Sommer, Ayman Ismail, Deana Rabinovich, Zhan Liu, Arjan van der Flier, Allison Goodman, Chris Furcht, Mark Tie, Tyler Carlage, Randy Mauldin, Terrence M. Dobrowsky, Zhiqian Liu, Oblaise Mercury, Lily Zhu, Baisong Mei, Volker Schellenberger, Haiyan Jiang, Glenn F. Pierce, Joe Salas, Robert Peters
Journal: Blood
Blood (2020) 135 (17): 1484–1496.
https://doi.org/10.1182/blood.2019001292
Published: 2020
Includes: Supplemental data
Journal Articles

A Novel Humanized Hemophilia-a Mouse Model to Facilitate Preclinical In Vivo Studies of Human Specific Fviiia-Mimetic Bispecific Antibodies

Wenjing Li, Jianxin Hu, PhD, Nina Leksa, PhD, Maria M Aleman, PhD, Robert Peters, PhD, Joe Salas, PhD, Arjan Van Der Flier, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2458.
https://doi.org/10.1182/blood-2018-99-119012
Published: 2018
Journal Articles

Phospholipid-Independent Activity of Fviiia Mimetic Bispecific Antibodies in Plasma

Maria M Aleman, PhD, Siddharth Jindal, MS, Nina Leksa, PhD, Robert Peters, PhD, Joe Salas, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2461.
https://doi.org/10.1182/blood-2018-99-119226
Published: 2018
Journal Articles

Optimization of Clot Formation Under Blood Flow in a Tissue Engineered Blood Vessel

Elena Kistanova, MA, Maria M Aleman, PhD, Yasuteru Sano, PhD, Fumitaka Shimizu, PhD, Takashi Kanda, PhD, Joe Salas, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2304.
https://doi.org/10.1182/blood.V130.Suppl_1.2304.2304
Published: 2017
Journal Articles

Extravascular Distribution of Conventional and Ehl FIX Products Using In Vivo SPECT Imaging Analysis in Hemophilia B Mice

Joe Salas, PhD, Arjan Van Der Flier, PhD, Vu P. Hong, PhD, Jennifer Dumont, PhD, Kelly D Orcutt, PhD, Apollina Goel, PhD, Robert Peters, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1061.
https://doi.org/10.1182/blood.V130.Suppl_1.1061.1061
Published: 2017
Journal Articles

Platelet-Targeted rFVIIa-Xten Improves Thrombin Generation and Fibrin Formation Compared to Recombinant FVIIa

Maria M. Aleman, PhD, Elena N. Kistanova, Nancy Moore, Volker Schellenberger, PhD, Robert Peters, PhD, Joe Salas, PhD
Journal: Blood
Blood (2015) 126 (23): 2269.
https://doi.org/10.1182/blood.V126.23.2269.2269
Published: 2015
Journal Articles

Novel Approach to Study Biodistribution and Accumulation of Pegylated Recombinant Factor VIII in Haemophilia A Mice

Vu P. Hong, PhD, Ayman Ismail, PhD, Nancy Moore, Robert Peters, PhD, Joe Salas, PhD
Journal: Blood
Blood (2015) 126 (23): 3517.
https://doi.org/10.1182/blood.V126.23.3517.3517
Published: 2015
Journal Articles

Evaluation of Enhanced in Vitro Plasma Stability of a Novel Long Acting Recombinant FVIIIFc-VWF-XTEN Fusion Protein

Ekta Seth Chhabra, PhD, Nancy Moore, Chris Furcht, Amy M Holthaus, BS, MS, Jiayun Liu, MS, Tongyao Liu, Volker Schellenberger, PhD, John Kulman, PhD, Joe Salas, PhD, Robert Peters, PhD
Journal: Blood
Blood (2015) 126 (23): 2279.
https://doi.org/10.1182/blood.V126.23.2279.2279
Published: 2015
Journal Articles

Enhancing the Acute Hemostatic Efficacy in Cynomolgus Monkeys By Targeting Activated Coagulation Factor VII to Platelets

Siyuan Tan, PhD, Joe Salas, PhD, Kai Chen, Tamera Ashworth, Sarah Smith, Elena Kistanova, Nancy Moore, Marisol Acosta, Anxhela Kole, David R. Light, PhD, Robert Peters, PhD, Haiyan Jiang, PhD
Journal: Blood
Blood (2014) 124 (21): 1488.
https://doi.org/10.1182/blood.V124.21.1488.1488
Published: 2014
Journal Articles

An Immunodeficient Mouse Model With Circulating Human Platelets To Evaluate The Platelet Clearance and Pharmacokinetics Of Platelet-Targeted Coagulation Factor VIIa

Siyuan Tan, PhD, Kai Chen, MS, Joe Salas, Ph.D., Robert Peters, Ph.D., David R. Light, PhD, Haiyan Jiang, PhD
Journal: Blood
Blood (2013) 122 (21): 2345.
https://doi.org/10.1182/blood.V122.21.2345.2345
Published: 2013