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Amy M. Holthaus
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Journal Articles

BIVV001, a new class of factor VIII replacement for hemophilia A that is independent of von Willebrand factor in primates and mice

Ekta Seth Chhabra, Tongyao Liu, John Kulman, Susannah Patarroyo-White, Buyue Yang, Qi Lu, Douglas Drager, Nancy Moore, Jiayun Liu, Amy M. Holthaus, Jurg M. Sommer, Ayman Ismail, Deana Rabinovich, Zhan Liu, Arjan van der Flier, Allison Goodman, Chris Furcht, Mark Tie, Tyler Carlage, Randy Mauldin, Terrence M. Dobrowsky, Zhiqian Liu, Oblaise Mercury, Lily Zhu, Baisong Mei, Volker Schellenberger, Haiyan Jiang, Glenn F. Pierce, Joe Salas, Robert Peters
Journal: Blood
Blood (2020) 135 (17): 1484–1496.
https://doi.org/10.1182/blood.2019001292
Published: 2020
Includes: Supplemental data
Journal Articles

Recombinant FIX/X-Bp from the Japanese Habu Snake Is a Universal Ligand for Purification of Highly Carboxylated Factor IX Variants and Factor X

Oblaise Mercury, BS, Lucy Liu, PhD, Ayman Ismail, PhD, Ming Zhang, PhD, Qi Lu, PhD, Tom O Cameron, PhD, Allison Goodman, BS, Liz Culyba, PhD, Rahul Ravindran Nair, BS, MS, Amy M Holthaus, BS, MS, John Kulman, PhD, Robert Peters, PhD
Journal: Blood
Blood (2015) 126 (23): 1081.
https://doi.org/10.1182/blood.V126.23.1081.1081
Published: 2015
Journal Articles

Evaluation of Enhanced in Vitro Plasma Stability of a Novel Long Acting Recombinant FVIIIFc-VWF-XTEN Fusion Protein

Ekta Seth Chhabra, PhD, Nancy Moore, Chris Furcht, Amy M Holthaus, BS, MS, Jiayun Liu, MS, Tongyao Liu, Volker Schellenberger, PhD, John Kulman, PhD, Joe Salas, PhD, Robert Peters, PhD
Journal: Blood
Blood (2015) 126 (23): 2279.
https://doi.org/10.1182/blood.V126.23.2279.2279
Published: 2015
Journal Articles

Recombinant FVIIIFc-VWF-XTEN Demonstrates Significant Bioavailability Following Subcutaneous Administration in Hemophilia A Mice

Douglas Drager, Sue Patarroyo-White, Hoson Chao, Ayman Ismail, PhD, Jiayun Liu, Amy M Holthaus, BS, MS, Ekta Chhabra, John Kulman, PhD, Volker Schellenberger, PhD, Tongyao Liu, Robert Peters, PhD
Journal: Blood
Blood (2015) 126 (23): 3492.
https://doi.org/10.1182/blood.V126.23.3492.3492
Published: 2015