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Journal Articles

Ex Vivo Expansion of Human Hematopoietic Stem Cells By Mimicking Intrinsic and Extrinsic Factors in Adult Bone Marrow

Xinjian Mao, Ning Zhang, Xi He, Ruochen Dong, Zhe Yang, Michael Epp, Linda Zhang, Allison Scott, Kate Hall, Anoja Perera, Jeff Haug, Hua Li, Cheng Luo, Chuan He, Linheng Li

Blood (2024) 144 (Supplement 1): 4042.

https://doi.org/10.1182/blood-2024-208449

Published: 2024

Journal Articles

Overcoming Immune Escape Via Targeting Akt-Wnt/β-Catenin By Artificial-Intelligence-Powered Peptide-Producing mRNAs

Zhe Yang, Negin Manshour, Xi He, Michael Epp, Jay Unruh, Xinjian Mao, Ruochen Dong, Dan Bradford, Shengping Huang, Fengyan Deng, Mark Hembree, Chongbei Zhao, Liang Xu, Dong Xu, Linheng Li

Blood (2024) 144 (Supplement 1): 1062.

https://doi.org/10.1182/blood-2024-200368

Published: 2024

Journal Articles

Spatial Transcriptomics Characterize Dynamic and Polarized Niche for Embryonic Hematopoiesis at Single-Cell Level

Xinjian Mao, Ning Zhang, Xi He, Laura F Bennett, Kate Hall, Kaitlyn Petentler, Allison Scott, Seth Malloy, Jeff Haug, Hua Li, Anoja Perera, Jay Unruh, Brian Slaughter, Paul Trainor, Nancy Speck, Linheng Li

Blood (2024) 144 (Supplement 1): 559.

https://doi.org/10.1182/blood-2024-208339

Published: 2024

Journal Articles

Characterization of Multicellular Niches Supporting Hematopoietic Stem Cells within Distinct Zones

Blood (2024) 144 (Supplement 1): 1306.

https://doi.org/10.1182/blood-2024-208450

Published: 2024

Journal Articles

Spatial Transcriptomics Reveals Distinct Hematopoietic Stem Cell Niches in Mouse Fetal Liver

Blood (2023) 142 (Supplement 1): 2700.

https://doi.org/10.1182/blood-2023-189880

Published: 2023

Journal Articles

Characterization of Niche Cells and Signals Regulating Stepwise Embryonic Hematopoiesis Using Slide-Seq and Merfish Spatial Transcriptomics

Xinjian Mao, Ning Zhang, Xi He, Kate Hall, Kaitlyn Petentler, Allison Scott, Seth Malloy, Jeff Haug, Hua Li, Anoja Perera, Jay Unruh, Brian Slaughter, Nancy Speck, Linheng Li

Blood (2023) 142 (Supplement 1): 4051.

https://doi.org/10.1182/blood-2023-190096

Published: 2023

Journal Articles

Characterization of Dynamic Niche Signaling Modules during Embryonic Hematopoietic Development Using Spatial Transcriptomics

Xinjian Mao, Ning Zhang, Kate Hall, Kaitlyn Petentler, Allison Scott, Seth Malloy, Fang Liu, Kevin Ferro, Jessica Bell, Erin Hamilton, Jeffrey Haug, Yongfu Wang, Hua Li, Anoja Perera, Jay Unruh, Brian Slaughter, Xi C He, Nancy Speck, Linheng Li

Blood (2022) 140 (Supplement 1): 8568–8569.

https://doi.org/10.1182/blood-2022-160325

Published: 2022

Journal Articles

Using Spatial Transcriptomics to Reveal Fetal Liver Hematopoietic Stem Cell-Niche Interactions

Ruochen Dong, Jonathon Russell, Hua Li, Seth Malloy, Kate Hall, Kaitlyn Petentler, Allison Scott, Cathy Mckinney, Sarah E Smith, Yongfu Wang, Anoja Perera, Sean McKinney, Brian Slaughter, Jay Unruh, Xi C He, Linheng Li

Blood (2022) 140 (Supplement 1): 1688–1689.

https://doi.org/10.1182/blood-2022-170352

Published: 2022

Journal Articles

p57Kip2 indirectly regulates AGM HSCs

Xinjian Mao, Linheng Li

Blood (2022) 140 (5): 411–412.

https://doi.org/10.1182/blood.2022017139

Published: 2022

Journal Articles

Using Spatial Transcriptomics to Reveal Fetal Liver Hematopoietic Stem Cell-Niche Interactions

Ruochen Dong, Jonathon Russell, Seth Malloy, Kate Hall, Sarah E Smith, Hua Li, Yongfu Wang, Anoja Perera, Sean McKinney, Brian Slaughter, Jay Unruh, Xi C He, Linheng Li

Blood (2021) 138 (Supplement 1): 3284.

https://doi.org/10.1182/blood-2021-153748

Published: 2021

Journal Articles

Long-Term Clearance of Senescent Cells Prevents the Hematopoietic Stem Cell Aging in Naturally Aged Mice

Yonghan He, MD, Jianhui Chang, Dongwen Lv, Ha-neui Kim, Maria Almeida, Xin Zhang, Xinjian Mao, PhD, Xinghui Zhao, PhD, Linheng Li, PhD, Judith Campisi, Ying Liang, MD PhD, Daohong Zhou

Blood (2019) 134 (Supplement_1): 1204.

https://doi.org/10.1182/blood-2019-123159

Published: 2019

Journal Articles

Treatment with Low-Dose Daunorubicin Reduces the Number of Leukemia Stem Cells in Patients with Relapsed/Refractory Acute Myeloid Leukemia

Tara L. Lin, MD, John M. Perry, PhD, Xi He, MD, Raymond P. Perez, MD, Gregory Reed, PhD, Margaret M. Brophy, Na Zhang, PhD, Scott Weir, PharmD, PhD, Joseph P. McGuirk, DO, Linheng Li, PhD

Blood (2017) 130 (Supplement 1): 1336.

https://doi.org/10.1182/blood.V130.Suppl_1.1336.1336

Published: 2017

Journal Articles

The Methylation-Sensitive Enhancer Derare Maintains Hematopoietic Stem Cells through Regulation of Hoxb Cluster

Pengxu Qian, PhD, Bony De Kumar, PhD, Youngwook Ahn, PhD, Christof Nolte, PhD, Ariel Paulson, PhD, Xi C He, MD, Zhenrui Li, John M. Perry, PhD, Meng Zhao, PhD, Fang Tao, Robb Krumlauf, PhD, Linheng Li, PhD

Blood (2016) 128 (22): 725.

https://doi.org/10.1182/blood.V128.22.725.725

Published: 2016

Journal Articles

Amino Acid Transporter X Is Required for Hematopoietic Stem Cell Maintenance through Regulating Specific Amino Acids Level

Zhenrui Li, MS, Keiyo Takubo, MD PhD, Pengxu Qian, PhD, Toshio Suda, MD PhD, Linheng Li, PhD

Blood (2015) 126 (23): 1166.

https://doi.org/10.1182/blood.V126.23.1166.1166

Published: 2015

Journal Articles

Chemoresistant Leukemia-Initiating Cell Expansion Is Inhibited By Targeting Oncogenic Self-Renewal

John M. Perry, PhD, Anuradha Roy, Xiuling Lu, PhD, Xi C. He, MD, Fang Tao, Meng Zhao, PhD, Pengxu Qian, PhD, Linheng Li, PhD

Blood (2015) 126 (23): 1860.

https://doi.org/10.1182/blood.V126.23.1860.1860

Published: 2015

Journal Articles

A Conserved Cis -Regulatory Retinoic Acid Responsive Element Is Essential for Maintenance of Primitive Hematopoietic Stem Cells through Regulation of Hoxb Cluster

Pengxu Qian, PhD, Youngwook Ahn, PhD, Bony De Kumar, PhD, Christof Nolte, PhD, Xi C. He, MD, Ariel Paulson, PhD, John M. Perry, PhD, Zhenrui Li, MS, Robb Krumlauf, PhD, Linheng Li, PhD

Blood (2015) 126 (23): 2377.

https://doi.org/10.1182/blood.V126.23.2377.2377

Published: 2015

Journal Articles

Osteoblast ablation burns out functional stem cells

Meng Zhao, Linheng Li

Blood (2015) 125 (17): 2590–2591.

https://doi.org/10.1182/blood-2015-03-633651

Published: 2015

Journal Articles

Metabolic Activity Distinguish Reserve and Primed HSCs

Zhenrui Li, BS, MS, Xi He, MD, Ariel Paulson, Meng Zhao, PhD, Pengxu Qian, PhD, Fang Tao, Wenxing Ding, PhD, Rick Dobrowsky, PhD, Linheng Li, PhD

Blood (2014) 124 (21): 2898.

https://doi.org/10.1182/blood.V124.21.2898.2898

Published: 2014

Journal Articles

The Imprinted Dlk1-Gtl2 Locus Epigenetically Regulates Primitive Hematopoietic Stem Cell Mitochondrial Function and Energy Metabolism Via Repression of PI3K/Akt/mTOR Pathway

Pengxu Qian, PhD, Xi He, MD, Ariel Paulson, Jeffrey S. Haug, BS, Linheng Li, PhD

Blood (2014) 124 (21): 243.

https://doi.org/10.1182/blood.V124.21.243.243

Published: 2014

Journal Articles

Resistance To Chemotherapy In Leukemia Cells Grown On An Extracellular Matrix-Based Leukemia Model Derived From Wharton’s Jelly

Dandan Li, Tara L. Lin, MD, Da Zhang, MD, Linheng Li, PhD, Richard A. Hopkins, Lisa Stehno-Bittel, PhD, Omar S. Aljitawi, MD

Blood (2013) 122 (21): 1388.

https://doi.org/10.1182/blood.V122.21.1388.1388

Published: 2013

NARROW

Ex Vivo Expansion of Human Hematopoietic Stem Cells By Mimicking Intrinsic and Extrinsic Factors in Adult Bone Marrow

Overcoming Immune Escape Via Targeting Akt-Wnt/β-Catenin By Artificial-Intelligence-Powered Peptide-Producing mRNAs

Spatial Transcriptomics Characterize Dynamic and Polarized Niche for Embryonic Hematopoiesis at Single-Cell Level

Characterization of Multicellular Niches Supporting Hematopoietic Stem Cells within Distinct Zones

Spatial Transcriptomics Reveals Distinct Hematopoietic Stem Cell Niches in Mouse Fetal Liver

Characterization of Niche Cells and Signals Regulating Stepwise Embryonic Hematopoiesis Using Slide-Seq and Merfish Spatial Transcriptomics

Characterization of Dynamic Niche Signaling Modules during Embryonic Hematopoietic Development Using Spatial Transcriptomics

Using Spatial Transcriptomics to Reveal Fetal Liver Hematopoietic Stem Cell-Niche Interactions

p57Kip2 indirectly regulates AGM HSCs

Using Spatial Transcriptomics to Reveal Fetal Liver Hematopoietic Stem Cell-Niche Interactions

Long-Term Clearance of Senescent Cells Prevents the Hematopoietic Stem Cell Aging in Naturally Aged Mice

Treatment with Low-Dose Daunorubicin Reduces the Number of Leukemia Stem Cells in Patients with Relapsed/Refractory Acute Myeloid Leukemia

The Methylation-Sensitive Enhancer Derare Maintains Hematopoietic Stem Cells through Regulation of Hoxb Cluster

Amino Acid Transporter X Is Required for Hematopoietic Stem Cell Maintenance through Regulating Specific Amino Acids Level

Chemoresistant Leukemia-Initiating Cell Expansion Is Inhibited By Targeting Oncogenic Self-Renewal

A Conserved Cis -Regulatory Retinoic Acid Responsive Element Is Essential for Maintenance of Primitive Hematopoietic Stem Cells through Regulation of Hoxb Cluster

Osteoblast ablation burns out functional stem cells

Metabolic Activity Distinguish Reserve and Primed HSCs

The Imprinted Dlk1-Gtl2 Locus Epigenetically Regulates Primitive Hematopoietic Stem Cell Mitochondrial Function and Energy Metabolism Via Repression of PI3K/Akt/mTOR Pathway

Resistance To Chemotherapy In Leukemia Cells Grown On An Extracellular Matrix-Based Leukemia Model Derived From Wharton’s Jelly

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American Society of Hematology

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ASH Publications

American Society of Hematology

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