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Karilyn Larkin
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Journal Articles

Large-Scale Post-Transplant TCR Deep Sequencing Reveals a Major T Cell Diversity Bottleneck with Post-Transplant Cyclophosphamide with Implications for Both Efficacy and Toxicity: Results of the BMT CTN 1801 Study

Leslie Kean, Steven J Siegel, Joseph T Schmalz, Stephanie A Bien, Danielle Scheffey, Catherine Sanders, Harlan Robins, Kristy Applegate, Merav Bar, Saurabh Chhabra, Sung W. Choi, William Clark, Suman r Das, Robert R. Jenq, Richard J. Jones, John Levine, Brent R. Logan, Hemant S. Murthy, Armin Rashidi, Marcie L. Riches, Wael Saber, Karamjeet S. Sandhu, Anthony D. Sung, Karilyn Larkin, Monzr M. Al Malki, Mahasweta Gooptu, Hany Elmariah, Amin Alousi, Lyndsey Runaas, Brian C. Shaffer, Andrew R. Rezvani, Najla El Jurdi, Alison Loren, Mary M. Horowitz, Javier Bolanos-Meade, Shernan G. Holtan, Ami S. Bhatt, Miguel-Angel Perales, Susan DeWolf
Journal: Blood
Blood (2023) 142 (Supplement 1): 475.
https://doi.org/10.1182/blood-2023-188032
Published: 2023
Journal Articles

PP2A is a therapeutically targetable driver of cell fate decisions via a c-Myc/p21 axis in human and murine acute myeloid leukemia

Swagata Goswami, Rajeswaran Mani, Jessica Nunes, Chi-Ling Chiang, Kevan Zapolnik, Eileen Hu, Frank Frissora, Xiaokui Mo, Logan A. Walker, Pearlly Yan, Ralf Bundschuh, Larry Beaver, Raymond Devine, Yo-Ting Tsai, Ann Ventura, Zhiliang Xie, Min Chen, Rosa Lapalombella, Alison Walker, Alice Mims, Karilyn Larkin, Nicole Grieselhuber, Chad Bennett, Mitch Phelps, Erin Hertlein, Gregory Behbehani, Sumithira Vasu, John C. Byrd, Natarajan Muthusamy
Journal: Blood
Blood (2022) 139 (9): 1340–1358.
https://doi.org/10.1182/blood.2020010344
Published: 2022
Includes: Supplemental data
Journal Articles

Effect of High Intensity Chemotherapy Vs Targeted Therapy on Survival in AML Patients Aged 60-75

Kieran D Sahasrabudhe, Melanie T Rebechi, Ying Huang, Greg K. Behbehani, Bhavana Bhatnagar, James S. Blachly, Bradley W Blaser, Uma Borate, Ramiro Garzon, Tamanna Haque, Karilyn Larkin, Meixiao Long, Alice S. Mims, Ayman Saad, Sumithira Vasu, Alison R. Walker, Sarah A Wall
Journal: Blood
Blood (2021) 138 (Supplement 1): 4125.
https://doi.org/10.1182/blood-2021-148676
Published: 2021
Journal Articles

Effect of Age on Outcomes of Allogeneic Transplantation in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome

Audrey M. Sigmund, Justin Jiang, Qiuhong Zhao, Patrick Elder, Ashley E. Rosko, Maria Chaudhry, Naresh Bumma, Abdullah Khan, Srinivas Devarakonda, Sumithira Vasu, Samantha Jaglowski, Alice S. Mims, Hannah Choe, Karilyn Larkin, Jonathan E Brammer, Sarah A Wall, Nicole Grieselhuber, Ayman Saad, Sam Penza, Marcos J.G. de Lima, Don M Benson, Jr., Yvonne A. Efebera, Nidhi Sharma
Journal: Blood
Blood (2021) 138 (Supplement 1): 3933.
https://doi.org/10.1182/blood-2021-146334
Published: 2021
Journal Articles

Romidepsin in Conditioning and Maintenance Mitigates Relapse Risk and Enhances NK-Cell Cytotoxicity in Patients Receiving Allogeneic Stem Cell Transplant for Aggressive T-Cell Malignancies: Results of a Phase I/II Clinical Trial

Chitra Hosing, Zachary Braunstein, Alaa M Ali, Benigno C. Valdez, Borje S. Andersson, Uday R. Popat, Sumithira Vasu, Karilyn Larkin, Sam Penza, Hannah Choe, Ayman Saad, Marcos J.G. de Lima, Lai Wei, Eric McLaughlin, Robin Nakkula, Amanda Campbell, Prashant Trikha, Marcin Puto, Basem M. William, Richard E. Champlin, Dean Anthony Lee, Jonathan E Brammer
Journal: Blood
Blood (2021) 138 (Supplement 1): 553.
https://doi.org/10.1182/blood-2021-152833
Published: 2021
Journal Articles

Multi-Dimensional Analysis of Adult Acute Myeloid Leukemia (AML) Landscape Cross-Continents Reveals Age Associated Trends in Mutations and Outcomes

Monica Cusan, Karilyn Larkin, Deedra Nicolet, Vindi Jurinovic, Krzysztof Mrózek, Aarif M. N. Batcha, Maja Rothenberg-Thurley, Stephanie Schneider, Maria Cristina Sauerland, Dennis Görlich, Utz Krug, Wolfgang E. Berdel, Bernhard Josef Woermann, Wolfgang Hiddemann, Jan Braess, Karsten Spiekermann, Jessica Kohlschmidt, James S. Blachly, Alice S. Mims, Christopher J. Walker, Christopher C. Oakes, Shelley Orwick, Andrew J Carroll, William Blum, Bayard L. Powell, Jonathan E Kolitz, Joseph O. Moore, Robert James Mayer, Richard A. Larson, Richard M. Stone, John C. Byrd, Klaus H. Metzeler, Tobias Herold, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2021) 138 (Supplement 1): 685.
https://doi.org/10.1182/blood-2021-153015
Published: 2021
Journal Articles

Utilizing Organ-Sparing Marrow Irradiation to Condition Patients Prior to Allogeneic Hematopoietic Cell Transplant with High-Risk Hematologic Malignancies: Results of a Pilot Study

Sumithira Vasu, Meghan Kromer, Qiuhong Zhao, Hannah Choe, Karilyn Larkin, Sarah A Wall, Samantha Jaglowski, Sam Penza, Jonathan E Brammer, Nidhi Sharma, Naduparambil Jacob, Marcos J.G. de Lima, Meng Welliver
Journal: Blood
Blood (2021) 138 (Supplement 1): 2856.
https://doi.org/10.1182/blood-2021-150948
Published: 2021
Journal Articles

High Early Death Rates, Treatment Resistance and Short Survival of Black Adolescent and Young Adults (AYAs) with Acute Myeloid Leukemia (AML) (Alliance)

Karilyn Larkin, Deedra Nicolet, Ben Kelly, Krzysztof Mrózek, Katherine E Miller, Saranga Wijeratne, Stephanie LaHaye, Jessica Kohlschmidt, James S. Blachly, Alice S. Mims, Christopher J. Walker, Christopher C. Oakes, Shelley Orwick, Isaiah Boateng, Jill Buss, Adrienne Heyrosa, Andrew J Carroll, William Blum, Bayard L. Powell, Jonathan E Kolitz, Joseph O. Moore, Robert James Mayer, Richard A. Larson, Richard M. Stone, Electra D. Paskett, John C. Byrd, Elaine R. Mardis, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2021) 138 (Supplement 1): 221.
https://doi.org/10.1182/blood-2021-151072
Published: 2021
Journal Articles

Trend in Survival in Patients Undergoing Allogeneic Stem Cell Transplantation: An Institutional Experience

Justin Jiang, BS, Audrey M. Sigmund, MD, Qiuhong Zhao, MS, Patrick Elder, MS, Don M. Benson, Jr., MD PhD, Ashley Rosko, MD, Maria Chaudhry, MD, Naresh Bumma, MD, Abdullah Khan, MBBS, MSc, Srinivas Devarakonda, MD, Sumithira Vasu, MDMBBS, Samantha Jaglowski, MD MPH, Basem M. William, MDMRCP, Alice S. Mims, MD, Hannah Choe, MD, Karilyn Larkin, MD, Jonathan E. Brammer, MD, Sarah A Wall, MD, Nicole Grieselhuber, MD PhD, Ayman Saad, MD MSc, Sam Penza, MD, Yvonne A. Efebera, MD MPH, Nidhi Sharma, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15.
https://doi.org/10.1182/blood-2020-138548
Published: 2020
Journal Articles

Impact of Race and Geographic Location on Outcomes in Allogeneic Transplant

Audrey M. Sigmund, MD, Qiuhong Zhao, MS, Justin Jiang, BS, Patrick Elder, MS, Don M. Benson, Jr., MD PhD, Ashley Rosko, MD, Maria Chaudhry, MD, Naresh Bumma, MD, Abdullah Khan, MBBS, MSc, Srinivas Devarakonda, MD, Sumithira Vasu, MDMBBS, Samantha Jaglowski, MD MPH, Basem M. William, MDMRCP, Alice S. Mims, MD, Hannah Choe, MD, Karilyn Larkin, MD, Jonathan E Brammer, MD, Sarah A Wall, MD, Nicole Grieselhuber, MD PhD, Ayman Saad, MD, Sam Penza, MD, Yvonne A. Efebera, MD MPH, Nidhi Sharma, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17–18.
https://doi.org/10.1182/blood-2020-140012
Published: 2020
Journal Articles

Impact of Chronic Graft-Versus-Host Disease on Non-Relapse Mortality

Justin Jiang, BS, Qiuhong Zhao, MS, Audrey M. Sigmund, MD, Patrick Elder, MS, Don M. Benson, Jr., MD PhD, Ashley Rosko, MD, Maria Chaudhry, MD, Naresh Bumma, MD, Abdullah Khan, MBBS, MSc, Srinivas Devarakonda, MD, Sumithira Vasu, MDMBBS, Samantha Jaglowski, MD MPH, Basem M. William, MDMRCP, Alice S. Mims, MD, Hannah Choe, MD, Karilyn Larkin, MD, Jonathan E. Brammer, MD, Sarah A Wall, MD, Nicole Grieselhuber, MD PhD, Ayman Saad, MD MSc, Sam Penza, MD, Yvonne A. Efebera, MD MPH, Nidhi Sharma, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42.
https://doi.org/10.1182/blood-2020-138755
Published: 2020
Journal Articles

Improvement in Survival of AML and MDS Patients Following Allogeneic Transplant: A Long-Term Institutional Experience

Audrey M. Sigmund, MD, Justin Jiang, BS, Qiuhong Zhao, MS, Patrick Elder, MS, Don M. Benson, Jr., MD PhD, Ashley Rosko, MD, Maria Chaudhry, MD, Naresh Bumma, MD, Abdullah Khan, MBBS, MSc, Srinivas Devarakonda, MD, Sumithira Vasu, MDMBBS, Samantha Jaglowski, MD MPH, Basem M. William, MDMRCP, Alice S. Mims, MD, Hannah Choe, MD, Karilyn Larkin, MD, Jonathan E Brammer, MD, Sarah A Wall, MD, Nicole Grieselhuber, MD PhD, Ayman Saad, MD, Sam Penza, MD, Yvonne A. Efebera, MD MPH, Nidhi Sharma, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30.
https://doi.org/10.1182/blood-2020-139933
Published: 2020
Journal Articles

A Retrospective Analysis of Outcomes Following Allogeneic Stem Cell Transplantation for Patients from Appalachian Counties

Amneet Bajwa, MDMBA, Qiuhong Zhao, MS, Joseph Coleman, Jonathan E Brammer, MD, Hannah Choe, MD, Yvonne A. Efebera, MD MPH, Karilyn Larkin, MD, Alice S. Mims, MD, Sam Penza, MD, Ayman Saad, MD, Sumithira Vasu, MDMBBS, Sarah A Wall, MD, Samantha Jaglowski, MD MPH
Journal: Blood
Blood (2020) 136 (Supplement 1): 20–21.
https://doi.org/10.1182/blood-2020-141541
Published: 2020
Journal Articles

Survival Implications of Opioid Use after Blood and Marrow Transplantation

Noha N. Soror, MD, Ashleigh Keiter, MS, Qiuhong Zhao, MS, Julianna Roddy, PharmD, Sam Penza, MD, Jonathan E Brammer, MD, Yvonne A. Efebera, MD MPH, Don M. Benson, Jr., MD PhD, Sumithra Vasu, MDMBBS, Alice S. Mims, MD, Bradley W Blaser, MD PhD, Hannah Choe, MD, Karilyn Larkin, MD, Nicole Grieselhuber, MD PhD, Sarah A Wall, MD, Ayman Saad, MD, Ashley Rosko, MD, Patrick Elder, MS, Maria Chaudhry, MD, Naresh Bumma, MD, Abdullah Khan, MBBS, MSc, Srinivas Devarakonda, MD, Samantha Jaglowski, MD MPH, Basem M. William, MDMRCP
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–3.
https://doi.org/10.1182/blood-2020-134463
Published: 2020
Journal Articles

NPM1 mutations Using Deep Amplicon Sequencing and Broad Next Generation Sequencing at the Time of Complete Remission Is Informative to Predicting Risk of Relapse Following Intensive Chemotherapy

Bhavana Bhatnagar, DO, Shelley Orwick, BS, Nyla A. Heerema, PhD, Alison R. Walker, MD, Alice S. Mims, MD, James S. Blachly, MD, Karilyn Larkin, MD, Nicole Grieselhuber, MD PhD, Gregory K. Behbehani, MD PhD, Apollinaire Ngankeu, Charles Thomas Gregory, BS, John C. Byrd, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1329.
https://doi.org/10.1182/blood-2019-130856
Published: 2019
Journal Articles

Effect of Early Post Transplantation Tacrolimus Concentration on the Risk of Acute Graft-Versus-Host Disease in Allogenic Stem Cell Transplantation

Nidhi Sharma, PhD, Bin Ni, MD, Qiuhong Zhao, MS, Patrick Elder, MS, Don M. Benson, Jr., MD PhD, Ashley E. Rosko, MD, Maria Chaudhry, MD, Naresh Bumma, MD, Abdullah Mohammad Khan, MBBS,MSc, Srinivas Devarakonda, MD, Sumithira Vasu, MDMBBS, Samantha Jaglowski, MDMPH, Basem M. William, MRCP,MD, Alice S. Mims, MD, Hannah K. Choe, MD, Karilyn Larkin, MD, Jonathan E Brammer, MD, Sarah A Wall, MD, Nicole Grieselhuber, MD PhD, Ayman Saad, MD, Sam Penza, MD, Yvonne A. Efebera, MD MPH
Journal: Blood
Blood (2019) 134 (Supplement_1): 4549.
https://doi.org/10.1182/blood-2019-122626
Published: 2019
Journal Articles

Comparison of Fixed Dose, Reduced-Intensity Conditioning with Busulfan and Fludarabine to Reduced PK-Guided Busulfan AUC Conditioning in Patients Undergoing Hematopoietic Stem Cell Transplant for AML/MDS

Brendan Rasor, PharmD, Tyler Dickerson, PharmD, Qiuhong Zhao, MS, Jonathan E Brammer, MD, Karilyn Larkin, MD, Samantha Jaglowski, MDMPH, Alice S. Mims, MD, Sam Penza, MD, Sumithira Vasu, MDMBBS, Sarah A Wall, MD, Basem M. William, MRCP,MD, Ayman Saad, MD, Julianna Roddy, PharmD, Hannah K. Choe, MD, Marcin Puto, PharmD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5715.
https://doi.org/10.1182/blood-2019-123657
Published: 2019
Journal Articles

CD37 Expression in Acute Myeloid Leukemia Provides New Target for Directed Therapy

Karilyn Larkin, MD, Erin Guth, MS, Bonnie K. Harrington, DVM, Nicole Grieselhuber, MD PhD, Natarajan Muthusamy, DVM, PhD, John C. Byrd, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4056.
https://doi.org/10.1182/blood-2018-99-117262
Published: 2018
Journal Articles

Impact of Cytokine Release Syndrome on Outcomes after T-Cell Replete Peripheral Blood Haploidentical Donor Transplantation

Caner Saygin, MD, John L Vaughn, MD, Joseph Coleman, Marcin Puto, PharmD, Julianna Roddy, PharmD, Sam Penza, MD, Jonathan E. Brammer, MD, Yvonne Efebera, MD, Don M. Benson, Jr., MD PhD, Sumithira Vasu, MD MBBS, Alison R. Walker, MD, Alice S. Mims, MD, Bhavana Bhatnagar, DO, Bradley Wayne Blaser, MD, Maria Chaudhry, MD, Hannah K. Choe, MD, Karilyn Larkin, MD, Meixiao Long, MD, Ashley E. Rosko, MD, Nicole Grieselhuber, MD PhD, Sarah A Wall, MD, Steven Devine, Samantha Jaglowski, MD MPH, Basem M. William, MRCP, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3357.
https://doi.org/10.1182/blood-2018-99-114100
Published: 2018
Journal Articles

Targeting BTK through microRNA in chronic lymphocytic leukemia

Arianna Bottoni, Lara Rizzotto, Tzung-Huei Lai, Chaomei Liu, Lisa L. Smith, Rose Mantel, Sean Reiff, Dalia El-Gamal, Karilyn Larkin, Amy J. Johnson, Rosa Lapalombella, Amy Lehman, William Plunkett, John C. Byrd, James S. Blachly, Jennifer A. Woyach, Deepa Sampath
Journal: Blood
Blood (2016) 128 (26): 3101–3112.
https://doi.org/10.1182/blood-2016-07-727750
Published: 2016
Includes: Supplemental data