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Karilyn Larkin
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Journal Articles

Secondary graft failure after PT-cy: Modeling a candidate risk assignment biomarker based on lymphocyte reconstitution.  Results from the BMT CTN 1801 study.

Free
Kayleigh Ingersoll Omdahl, Steven Siegel, Jiayi Dong, Susan DeWolf, Kyle Hebert, Donna Neuberg, Isabella Schichter, Alexandre Albanese, Paul Keskula, Lorenzo Cagnin, Kristy Applegate, Merav Bar, Saurabh Chhabra, Sung Choi, William Clark, Suman Das, Robert Jenq, Richard Jones, John Levine, Brent Logan, Michael Martens, Hemant Murthy, Armin Rashidi, Marcie Riches, Wael Saber, Karamjeet Sandhu, Anthony Sung, Karilyn Larkin, Monzr M. Al Malki, Mahasweta Gooptu, Hany Elmariah, Amin Alousi, Lyndsey Runaas, Brian Shaffer, Andrew Rezvani, Najla El Jurdi, Alison Loren, Mary Horowitz, Javier Bolanos-Meade, Shernan Holtan, Ami Bhatt, Miguel-Angel Perales, Leslie Kean
Journal: Blood
Blood (2025) 146 (Supplement 1): 4198.
https://doi.org/10.1182/blood-2025-4198
Published: 2025
Journal Articles

A phase 1/2, first-in-human, multicenter, open-label trial evaluating the safety, tolerability, and antileukemic activity of Debio 1562M in patients with recurrent refractory acute myeloid leukemia (AML)

Free
Naval Daver, Andrew Sochacki, Monzr M. Al Malki, Eunice Wang, Marianna Muller, Anne Bellon, Sandrine Micallef, David Sallman, Karilyn Larkin
Journal: Blood
Blood (2025) 146 (Supplement 1): 5194.
https://doi.org/10.1182/blood-2025-5194
Published: 2025
Journal Articles

Mismatching of unrelated donors beyond a single HLA-locus does not adversely impact outcomes at one year following transplantation: Results from the NMDP sponsored ACCESS study

Free
Monzr M. Al Malki, Stephanie Bo-Subait, Brent Logan, Sarah Smith, Erin Leckrone, Heather Stefanski, Jeffery Auletta, Stephen Spellman, Craig Malmberg, Medhat Askar, Rachel Cusatis, Brian Shaffer, Dipenkumar Modi, Farhad Khimani, Mahasweta Gooptu, Mehdi Hamadani, Martin Maiers, Joseph Stanek, Javier Meade, Uttam Rao, Jordan Milner, Ramzi Abboud, Katarzyna Jamieson, George Carrum, Bhagirathbhai Dholaria, William Hogan, Ran Reshef, Satyajit Kosuri, Rachel Cook, Karen Ballen, Alison Loren, Karilyn Larkin, Sally Arai, Muna Qayed, Sung Choi, Larisa Broglie, Bronwen Shaw, Steven Devine, Antonio Jimenez Jimenez
Journal: Blood
Blood (2025) 146 (Supplement 1): 936.
https://doi.org/10.1182/blood-2025-936
Published: 2025
Journal Articles

Toxicity of reduced dose versus standard dose pegaspargase in adolescents and young adults with acute lymphoblastic leukemia

Free
Megan Fleming, Allyson Waller, Subodh Bhatta, Pooja Kumar, Tracelyn Freeman, Lexus Frazier, Nilmarie Ayala-Fontanez, Adithya Ghantae, Sharon Loo, Jasmine Kainth, Ying Huang, James Blachly, Bradley Blaser, Uma Borate, Ann-Kathrin Eisfeld, Nicole Grieselhuber, Shivani Handa, Jayanshu Jain, Karilyn Larkin, Meixiao Long, Alice Mims, Andrew Srisuwananukorn, Gregory Behbehani
Journal: Blood
Blood (2025) 146 (Supplement 1): 3344.
https://doi.org/10.1182/blood-2025-3344
Published: 2025
Journal Articles

Phase II Study of post transplant cyclophosphamide-based graft versus host disease prophylaxis after HLA-mismatched unrelated donor transplantation and reduced intensity conditioning: Results from the NMDP-sponsored access expansion Study

Free
Mahasweta Gooptu, Monzr M. Al Malki, Stephanie Bo-Subait, Brent Logan, Erin Leckrone, Sarah Smith, Heather Stefanski, Jeffery Auletta, Stephen Spellman, Craig Malmberg, Medhat Askar, Rachel Cusatis, Farhad Khimani, Dipenkumar Modi, Mehdi Hamadani, Martin Maiers, Joseph Stanek, Javier Meade, Uttam Rao, Jordan Milner, Ramzi Abboud, Katarzyna Jamieson, George Carrum, Bhagirathbhai Dholaria, William Hogan, Ran Reshef, Satyajit Kosuri, Rachel Cook, Karen Ballen, Alison Loren, Karilyn Larkin, Sally Arai, Muna Qayed, Sung Choi, Larisa Broglie, Bronwen Shaw, Steven Devine, Antonio Jimenez Jimenez, Brian Shaffer
Journal: Blood
Blood (2025) 146 (Supplement 1): 4232.
https://doi.org/10.1182/blood-2025-4232
Published: 2025
Journal Articles

Evaluation of cytarabine consolidation dosing in older adult patients with Acute Myeloid Leukemia

Free
Pooja Kumar, Deedra Nicolet, Tracelyn Freeman, Lexus Frazier, Allyson Waller, Megan Fleming, Michael Walker, Gregory Behbehani, James Blachly, Uma Borate, Nicole Grieselhuber, Shivani Handa, Jayanshu Jain, Karilyn Larkin, Meixiao Long, Ann-Kathrin Eisfeld, Alice Mims
Journal: Blood
Blood (2025) 146 (Supplement 1): 3408.
https://doi.org/10.1182/blood-2025-3408
Published: 2025
Journal Articles

Combined TCR-seq and single-cell RNA-seq reveal distinct origins for antiviral immunity after post-transplant cyclophosphamide and tac/MTX gvhd prophylaxis: Results from the BMT CTN 1801 study

Free
Steven Siegel, Susan DeWolf, Joseph Schmalz, Nicholas Winn, James Kaminski, Stephanie Bien, Catherine Sanders, Harlan Robins, Jillian Zavistaski, Isabella Schichter, Lea Steinberg, Kristy Applegate, Merav Bar, Saurabh Chhabra, Sung Choi, William Clark, Suman Das, Robert Jenq, Richard Jones, John Levine, Brent Logan, Michael Martens, Hemant Murthy, Armin Rashidi, Marcie Riches, Wael Saber, Karamjeet Sandhu, Anthony Sung, Karilyn Larkin, Monzr M. Al Malki, Mahasweta Gooptu, Hany Elmariah, Amin Alousi, Lyndsey Runaas, Brian Shaffer, Andrew Rezvani, N El Jurdi, Alison Loren, Mary Horowitz, Mehdi Hamadani, Javier Bolanos-Meade, Shernan Holtan, Ami Bhatt, Miguel-Angel Perales, Leslie Kean
Journal: Blood
Blood (2025) 146 (Supplement 1): 818.
https://doi.org/10.1182/blood-2025-818
Published: 2025
Journal Articles

Large-Scale Post-Transplant TCR Deep Sequencing Reveals a Major T Cell Diversity Bottleneck with Post-Transplant Cyclophosphamide with Implications for Both Efficacy and Toxicity: Results of the BMT CTN 1801 Study

Free
Leslie Kean, Steven J Siegel, Joseph T Schmalz, Stephanie A Bien, Danielle Scheffey, Catherine Sanders, Harlan Robins, Kristy Applegate, Merav Bar, Saurabh Chhabra, Sung W. Choi, William Clark, Suman r Das, Robert R. Jenq, Richard J. Jones, John Levine, Brent R. Logan, Hemant S. Murthy, Armin Rashidi, Marcie L. Riches, Wael Saber, Karamjeet S. Sandhu, Anthony D. Sung, Karilyn Larkin, Monzr M. Al Malki, Mahasweta Gooptu, Hany Elmariah, Amin Alousi, Lyndsey Runaas, Brian C. Shaffer, Andrew R. Rezvani, Najla El Jurdi, Alison Loren, Mary M. Horowitz, Javier Bolanos-Meade, Shernan G. Holtan, Ami S. Bhatt, Miguel-Angel Perales, Susan DeWolf
Journal: Blood
Blood (2023) 142 (Supplement 1): 475.
https://doi.org/10.1182/blood-2023-188032
Published: 2023
Journal Articles

PP2A is a therapeutically targetable driver of cell fate decisions via a c-Myc/p21 axis in human and murine acute myeloid leukemia

Open Access
Swagata Goswami, Rajeswaran Mani, Jessica Nunes, Chi-Ling Chiang, Kevan Zapolnik, Eileen Hu, Frank Frissora, Xiaokui Mo, Logan A. Walker, Pearlly Yan, Ralf Bundschuh, Larry Beaver, Raymond Devine, Yo-Ting Tsai, Ann Ventura, Zhiliang Xie, Min Chen, Rosa Lapalombella, Alison Walker, Alice Mims, Karilyn Larkin, Nicole Grieselhuber, Chad Bennett, Mitch Phelps, Erin Hertlein, Gregory Behbehani, Sumithira Vasu, John C. Byrd, Natarajan Muthusamy
Journal: Blood
Blood (2022) 139 (9): 1340–1358.
https://doi.org/10.1182/blood.2020010344
Published: 2022
Includes: Supplemental data
Journal Articles

High Early Death Rates, Treatment Resistance and Short Survival of Black Adolescent and Young Adults (AYAs) with Acute Myeloid Leukemia (AML) (Alliance)

Free
Karilyn Larkin, Deedra Nicolet, Ben Kelly, Krzysztof Mrózek, Katherine E Miller, Saranga Wijeratne, Stephanie LaHaye, Jessica Kohlschmidt, James S. Blachly, Alice S. Mims, Christopher J. Walker, Christopher C. Oakes, Shelley Orwick, Isaiah Boateng, Jill Buss, Adrienne Heyrosa, Andrew J Carroll, William Blum, Bayard L. Powell, Jonathan E Kolitz, Joseph O. Moore, Robert James Mayer, Richard A. Larson, Richard M. Stone, Electra D. Paskett, John C. Byrd, Elaine R. Mardis, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2021) 138 (Supplement 1): 221.
https://doi.org/10.1182/blood-2021-151072
Published: 2021
Journal Articles

Romidepsin in Conditioning and Maintenance Mitigates Relapse Risk and Enhances NK-Cell Cytotoxicity in Patients Receiving Allogeneic Stem Cell Transplant for Aggressive T-Cell Malignancies: Results of a Phase I/II Clinical Trial

Free
Chitra Hosing, Zachary Braunstein, Alaa M Ali, Benigno C. Valdez, Borje S. Andersson, Uday R. Popat, Sumithira Vasu, Karilyn Larkin, Sam Penza, Hannah Choe, Ayman Saad, Marcos J.G. de Lima, Lai Wei, Eric McLaughlin, Robin Nakkula, Amanda Campbell, Prashant Trikha, Marcin Puto, Basem M. William, Richard E. Champlin, Dean Anthony Lee, Jonathan E Brammer
Journal: Blood
Blood (2021) 138 (Supplement 1): 553.
https://doi.org/10.1182/blood-2021-152833
Published: 2021
Journal Articles

Multi-Dimensional Analysis of Adult Acute Myeloid Leukemia (AML) Landscape Cross-Continents Reveals Age Associated Trends in Mutations and Outcomes

Free
Monica Cusan, Karilyn Larkin, Deedra Nicolet, Vindi Jurinovic, Krzysztof Mrózek, Aarif M. N. Batcha, Maja Rothenberg-Thurley, Stephanie Schneider, Maria Cristina Sauerland, Dennis Görlich, Utz Krug, Wolfgang E. Berdel, Bernhard Josef Woermann, Wolfgang Hiddemann, Jan Braess, Karsten Spiekermann, Jessica Kohlschmidt, James S. Blachly, Alice S. Mims, Christopher J. Walker, Christopher C. Oakes, Shelley Orwick, Andrew J Carroll, William Blum, Bayard L. Powell, Jonathan E Kolitz, Joseph O. Moore, Robert James Mayer, Richard A. Larson, Richard M. Stone, John C. Byrd, Klaus H. Metzeler, Tobias Herold, Ann-Kathrin Eisfeld
Journal: Blood
Blood (2021) 138 (Supplement 1): 685.
https://doi.org/10.1182/blood-2021-153015
Published: 2021
Journal Articles

Effect of High Intensity Chemotherapy Vs Targeted Therapy on Survival in AML Patients Aged 60-75

Free
Kieran D Sahasrabudhe, Melanie T Rebechi, Ying Huang, Greg K. Behbehani, Bhavana Bhatnagar, James S. Blachly, Bradley W Blaser, Uma Borate, Ramiro Garzon, Tamanna Haque, Karilyn Larkin, Meixiao Long, Alice S. Mims, Ayman Saad, Sumithira Vasu, Alison R. Walker, Sarah A Wall
Journal: Blood
Blood (2021) 138 (Supplement 1): 4125.
https://doi.org/10.1182/blood-2021-148676
Published: 2021
Journal Articles

Effect of Age on Outcomes of Allogeneic Transplantation in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome

Free
Audrey M. Sigmund, Justin Jiang, Qiuhong Zhao, Patrick Elder, Ashley E. Rosko, Maria Chaudhry, Naresh Bumma, Abdullah Khan, Srinivas Devarakonda, Sumithira Vasu, Samantha Jaglowski, Alice S. Mims, Hannah Choe, Karilyn Larkin, Jonathan E Brammer, Sarah A Wall, Nicole Grieselhuber, Ayman Saad, Sam Penza, Marcos J.G. de Lima, Don M Benson, Jr., Yvonne A. Efebera, Nidhi Sharma
Journal: Blood
Blood (2021) 138 (Supplement 1): 3933.
https://doi.org/10.1182/blood-2021-146334
Published: 2021
Journal Articles

Utilizing Organ-Sparing Marrow Irradiation to Condition Patients Prior to Allogeneic Hematopoietic Cell Transplant with High-Risk Hematologic Malignancies: Results of a Pilot Study

Free
Sumithira Vasu, Meghan Kromer, Qiuhong Zhao, Hannah Choe, Karilyn Larkin, Sarah A Wall, Samantha Jaglowski, Sam Penza, Jonathan E Brammer, Nidhi Sharma, Naduparambil Jacob, Marcos J.G. de Lima, Meng Welliver
Journal: Blood
Blood (2021) 138 (Supplement 1): 2856.
https://doi.org/10.1182/blood-2021-150948
Published: 2021
Journal Articles

Survival Implications of Opioid Use after Blood and Marrow Transplantation

Free
Noha N. Soror, MD, Ashleigh Keiter, MS, Qiuhong Zhao, MS, Julianna Roddy, PharmD, Sam Penza, MD, Jonathan E Brammer, MD, Yvonne A. Efebera, MD MPH, Don M. Benson, Jr., MD PhD, Sumithra Vasu, MDMBBS, Alice S. Mims, MD, Bradley W Blaser, MD PhD, Hannah Choe, MD, Karilyn Larkin, MD, Nicole Grieselhuber, MD PhD, Sarah A Wall, MD, Ayman Saad, MD, Ashley Rosko, MD, Patrick Elder, MS, Maria Chaudhry, MD, Naresh Bumma, MD, Abdullah Khan, MBBS, MSc, Srinivas Devarakonda, MD, Samantha Jaglowski, MD MPH, Basem M. William, MDMRCP
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–3.
https://doi.org/10.1182/blood-2020-134463
Published: 2020
Journal Articles

Impact of Chronic Graft-Versus-Host Disease on Non-Relapse Mortality

Free
Justin Jiang, BS, Qiuhong Zhao, MS, Audrey M. Sigmund, MD, Patrick Elder, MS, Don M. Benson, Jr., MD PhD, Ashley Rosko, MD, Maria Chaudhry, MD, Naresh Bumma, MD, Abdullah Khan, MBBS, MSc, Srinivas Devarakonda, MD, Sumithira Vasu, MDMBBS, Samantha Jaglowski, MD MPH, Basem M. William, MDMRCP, Alice S. Mims, MD, Hannah Choe, MD, Karilyn Larkin, MD, Jonathan E. Brammer, MD, Sarah A Wall, MD, Nicole Grieselhuber, MD PhD, Ayman Saad, MD MSc, Sam Penza, MD, Yvonne A. Efebera, MD MPH, Nidhi Sharma, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42.
https://doi.org/10.1182/blood-2020-138755
Published: 2020
Journal Articles

Improvement in Survival of AML and MDS Patients Following Allogeneic Transplant: A Long-Term Institutional Experience

Free
Audrey M. Sigmund, MD, Justin Jiang, BS, Qiuhong Zhao, MS, Patrick Elder, MS, Don M. Benson, Jr., MD PhD, Ashley Rosko, MD, Maria Chaudhry, MD, Naresh Bumma, MD, Abdullah Khan, MBBS, MSc, Srinivas Devarakonda, MD, Sumithira Vasu, MDMBBS, Samantha Jaglowski, MD MPH, Basem M. William, MDMRCP, Alice S. Mims, MD, Hannah Choe, MD, Karilyn Larkin, MD, Jonathan E Brammer, MD, Sarah A Wall, MD, Nicole Grieselhuber, MD PhD, Ayman Saad, MD, Sam Penza, MD, Yvonne A. Efebera, MD MPH, Nidhi Sharma, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30.
https://doi.org/10.1182/blood-2020-139933
Published: 2020
Journal Articles

Trend in Survival in Patients Undergoing Allogeneic Stem Cell Transplantation: An Institutional Experience

Free
Justin Jiang, BS, Audrey M. Sigmund, MD, Qiuhong Zhao, MS, Patrick Elder, MS, Don M. Benson, Jr., MD PhD, Ashley Rosko, MD, Maria Chaudhry, MD, Naresh Bumma, MD, Abdullah Khan, MBBS, MSc, Srinivas Devarakonda, MD, Sumithira Vasu, MDMBBS, Samantha Jaglowski, MD MPH, Basem M. William, MDMRCP, Alice S. Mims, MD, Hannah Choe, MD, Karilyn Larkin, MD, Jonathan E. Brammer, MD, Sarah A Wall, MD, Nicole Grieselhuber, MD PhD, Ayman Saad, MD MSc, Sam Penza, MD, Yvonne A. Efebera, MD MPH, Nidhi Sharma, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15.
https://doi.org/10.1182/blood-2020-138548
Published: 2020
Journal Articles

Impact of Race and Geographic Location on Outcomes in Allogeneic Transplant

Free
Audrey M. Sigmund, MD, Qiuhong Zhao, MS, Justin Jiang, BS, Patrick Elder, MS, Don M. Benson, Jr., MD PhD, Ashley Rosko, MD, Maria Chaudhry, MD, Naresh Bumma, MD, Abdullah Khan, MBBS, MSc, Srinivas Devarakonda, MD, Sumithira Vasu, MDMBBS, Samantha Jaglowski, MD MPH, Basem M. William, MDMRCP, Alice S. Mims, MD, Hannah Choe, MD, Karilyn Larkin, MD, Jonathan E Brammer, MD, Sarah A Wall, MD, Nicole Grieselhuber, MD PhD, Ayman Saad, MD, Sam Penza, MD, Yvonne A. Efebera, MD MPH, Nidhi Sharma, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 17–18.
https://doi.org/10.1182/blood-2020-140012
Published: 2020