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Journal Articles

A Pilot Multi-Pronged Approach to Measuring Endothelial Dysfunction and Predict the Development of Endothelial Disorders and Death Post Hematopoietic Cell Transplantation (HCT)

Michelle L Schoettler, Ritu Sachdeva, Muna Qayed, Benjamin Watkins, Suhag Parikh, Kathryn Leung, Elizabeth O Stenger, Ann Haight, Katherine Silvis, Yvonne Suessmuth, Adrianna Westbrook, Kirsten M. Williams

Blood (2024) 144 (Supplement 1): 4888.

https://doi.org/10.1182/blood-2024-208492

Published: 2024

Journal Articles

Higher abatacept exposure after transplant decreases acute GVHD risk without increasing adverse events

Blood (2023) 142 (8): 700–710.

https://doi.org/10.1182/blood.2023020035

Published: 2023

Includes: Supplemental data

Journal Articles

Abatacept for the Prevention of Gvhd in Pediatric and Adult Patients Receiving 7/8 HLA-Mismatched Unrelated Transplant for Hematologic Malignancies: A Real-World Analysis

Sharmila Raghunandan, Lev Gorfinkel, Michael Graiser, Brandi Bratrude, Kayla Betz, Yvonne Suessmuth, Scott Gillespie, Adrianna Lynn Westbrook, Kirsten M. Williams, Michelle Schoettler, Amelia Langston, Leslie Kean, Muna Qayed, John T. Horan, Benjamin Watkins

Blood (2022) 140 (Supplement 1): 7653–7655.

https://doi.org/10.1182/blood-2022-163627

Published: 2022

Journal Articles

Early Breakthrough T Cell Proliferation Despite CNI/MTX Prophylaxis Is a Harbinger of Acute Gvhd (AGVHD) and Is Controlled By Abatacept: Mechanism of Success of the ABA2 Agvhd Prevention Trial

Alexandre Albanese, Alal Eran, Yvonne Suessmuth, Kayla Betz, Brandi Bratrude, Paula Keskula, Lorenzo Cagnin, Amelia Langston, Muna Qayed, John T. Horan, Bruce R. Blazar, Benjamin Watkins, Leslie S. Kean

Blood (2022) 140 (Supplement 1): 274–275.

https://doi.org/10.1182/blood-2022-170693

Published: 2022

Journal Articles

Single-Cell RNA-Seq Reveals an Interferon-Driven Inflammatory CD4 Naïve T Cell Subpopulation at Day 100 in Hematopoietic Stem Cell Transplant Patients That Ultimately Develop Chronic Gvhd

Alexandre Albanese, Edward Chen, Jillian Zavistaski, Kayla Betz, Yvonne Suessmuth, Lorenzo Cagnin, Paula Keskula, Kyle Kimler, James Kaminski, Bruce R. Blazar, Benjamin Watkins, Leslie S. Kean

Blood (2022) 140 (Supplement 1): 270–271.

https://doi.org/10.1182/blood-2022-170214

Published: 2022

Journal Articles

Predicting Immune Pathology after Hematopoietic Stem Cell Transplant with Transcriptomics: Naïve CD4 T Cell Expansion at Day 100 Predicts Patients with De Novo Chronic Gvhd

Ben Watkins, MD, James Kaminski, Muna Qayed, MDMSc, Kayla Betz, BS, Yvonne Suessmuth, PhD, Brandi Bratrude, Alison Yu, PhD, Victor Tkachev, PhD, Kathryn Pellegrini, Steven Bosinger, PhD, Bruce R. Blazar, MD, John T. Horan, MDMPH, Amelia Langston, MD, Leslie Kean, MD PhD

Blood (2020) 136 (Supplement 1): 38–39.

https://doi.org/10.1182/blood-2020-139488

Published: 2020

Journal Articles

Potent Interaction between CMV Reactivation and Gvhd: Immunologic Evidence for Blunting of CMV-Driven Immune Reconstitution in the Setting of Gvhd

Yvonne Suessmuth, PhD, Kayla Betz, BS, Alison Yu, PhD, Brandi Bratrude, Benjamin Watkins, MD, Muna Qayed, MDMSc, John T. Horan, MDMPH, Leslie Kean, MD PhD, Amelia Langston, MD

Blood (2020) 136 (Supplement 1): 50.

https://doi.org/10.1182/blood-2020-141856

Published: 2020

Journal Articles

Transcriptomic Analysis of CD4+ T Cell Dysfunction during Gvhd: Evidence for Profound Reprograming of T Cell Signaling during Acute Gvhd That Is Controlled during CD28:CD80/86 Costimulation Blockade with Abatacept

Benjamin Watkins, Yvonne Suessmuth, Kayla Betz, BS, Alison Yu, PhD, Brandi Bratrude, Muna Qayed, MD MSc, Kathryn Pellegrini, Steven Bosinger, Amelia Langston, MD, John T. Horan, MDMPH, Bruce R. Blazar, MD, Leslie Kean, MD PhD

Blood (2019) 134 (Supplement_1): 596.

https://doi.org/10.1182/blood-2019-131955

Published: 2019

Journal Articles

T Cell Costimulation Blockade with Abatacept Nearly Eliminates Early Severe Acute Graft Versus Host Disease after HLA-Mismatched (7/8 HLA Matched) Unrelated Donor Transplant, with a Favorable Impact on Disease-Free and Overall Survival

Blood (2017) 130 (Supplement 1): 212.

https://doi.org/10.1182/blood.V130.Suppl_1.212.212

Published: 2017

Journal Articles

CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRβ repertoire

Blood (2015) 125 (25): 3835–3850.

https://doi.org/10.1182/blood-2015-03-631853

Published: 2015

Includes: Supplemental data

Journal Articles

The myeloproliferative disorder–associated JAK2 V617F mutant escapes negative regulation by suppressor of cytokine signaling 3

Michelle B. Hookham, Joanne Elliott, Yvonne Suessmuth, Judith Staerk, Alister C. Ward, William Vainchenker, Melanie J. Percy, Mary Frances McMullin, Stefan N. Constantinescu, James A. Johnston

Blood (2007) 109 (11): 4924–4929.

https://doi.org/10.1182/blood-2006-08-039735

Published: 2007

Includes: Supplemental data

NARROW

A Pilot Multi-Pronged Approach to Measuring Endothelial Dysfunction and Predict the Development of Endothelial Disorders and Death Post Hematopoietic Cell Transplantation (HCT)

Higher abatacept exposure after transplant decreases acute GVHD risk without increasing adverse events

Abatacept for the Prevention of Gvhd in Pediatric and Adult Patients Receiving 7/8 HLA-Mismatched Unrelated Transplant for Hematologic Malignancies: A Real-World Analysis

Early Breakthrough T Cell Proliferation Despite CNI/MTX Prophylaxis Is a Harbinger of Acute Gvhd (AGVHD) and Is Controlled By Abatacept: Mechanism of Success of the ABA2 Agvhd Prevention Trial

Single-Cell RNA-Seq Reveals an Interferon-Driven Inflammatory CD4 Naïve T Cell Subpopulation at Day 100 in Hematopoietic Stem Cell Transplant Patients That Ultimately Develop Chronic Gvhd

Predicting Immune Pathology after Hematopoietic Stem Cell Transplant with Transcriptomics: Naïve CD4 T Cell Expansion at Day 100 Predicts Patients with De Novo Chronic Gvhd

Potent Interaction between CMV Reactivation and Gvhd: Immunologic Evidence for Blunting of CMV-Driven Immune Reconstitution in the Setting of Gvhd

Transcriptomic Analysis of CD4+ T Cell Dysfunction during Gvhd: Evidence for Profound Reprograming of T Cell Signaling during Acute Gvhd That Is Controlled during CD28:CD80/86 Costimulation Blockade with Abatacept

T Cell Costimulation Blockade with Abatacept Nearly Eliminates Early Severe Acute Graft Versus Host Disease after HLA-Mismatched (7/8 HLA Matched) Unrelated Donor Transplant, with a Favorable Impact on Disease-Free and Overall Survival

CMV reactivation drives posttransplant T-cell reconstitution and results in defects in the underlying TCRβ repertoire

The myeloproliferative disorder–associated JAK2 V617F mutant escapes negative regulation by suppressor of cytokine signaling 3

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American Society of Hematology

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ASH Publications

American Society of Hematology

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