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Journal Articles

Preliminary Results of a Phase 2a Clinical Trial to Evaluate Safety, Tolerability and Antiviral Activity of Intravenous Brincidofovir (BCV IV) in Immunocompromised Patients with Adenovirus Infection

Michael Grimley, Gabriela Maron, Carlos A Gomez, Vinod K. Prasad, Jasmeen Dara, Genovefa A Papanicolaou, Koji Fukushima, Robert F. Wynn, Michael Boeckh

Blood (2023) 142 (Supplement 1): 112.

https://doi.org/10.1182/blood-2023-179901

Published: 2023

Journal Articles

Higher abatacept exposure after transplant decreases acute GVHD risk without increasing adverse events

Blood (2023) 142 (8): 700–710.

https://doi.org/10.1182/blood.2023020035

Published: 2023

Includes: Supplemental data

Journal Articles

Safety and Efficacy of Aru-1801 in Patients with Sickle Cell Disease: Early Results from the Phase 1/2 Momentum Study of a Modified Gamma Globin Gene Therapy and Reduced Intensity Conditioning

Michael Grimley, Monika Asnani, Archana Shrestha, Sydney Felker, Carolyn Lutzko, Paritha I. Arumugam, Scott Witting, Jennifer Knight-Madden, Omar Niss, Charles T. Quinn, Chris Lo, Courtney R. Little, Alisa Dong, Punam Malik

Blood (2021) 138 (Supplement 1): 3970.

https://doi.org/10.1182/blood-2021-147469

Published: 2021

Journal Articles

Early Results from a Phase 1/2 Study of Aru-1801 Gene Therapy for Sickle Cell Disease (SCD): Manufacturing Process Enhancements Improve Efficacy of a Modified Gamma Globin Lentivirus Vector and Reduced Intensity Conditioning Transplant

Michael Grimley, MD, Monika Asnani, PhD, Archana Shrestha, Sydney Felker, Carolyn Lutzko, PhD, Paritha I. Arumugam, PhD, Scott Witting, PhD, Jennifer Knight-Madden, MBBS, PhD, Omar Niss, MD, Charles T. Quinn, MD, Chris Lo, BS, Courtney R Little, BSN, Joseph W. McIntosh, MD, Punam Malik, MD

Blood (2020) 136 (Supplement 1): 20–21.

https://doi.org/10.1182/blood-2020-140963

Published: 2020

Journal Articles

A Multi-Center Case Series, Systematic Review and Meta-Analysis of Neonatal Hemophagocytic Lymphohistiocytosis

Christen L. Ebens, MDMPH, Adam S DuVall, MD, Todd E. DeFor, MS, Marketa T. Dimitrov, MD, David Frame, Michael A. Briones, Michael Grimley, MD, Sarita Joshi, MBBS,MD, Rebecca A. Marsh, Evan Shereck, MD, Mark Vander Lugt, MD, James A. Connelly, MD, Kelly J. Walkovich, MD

Blood (2020) 136 (Supplement 1): 19–20.

https://doi.org/10.1182/blood-2020-142895

Published: 2020

Journal Articles

Granulocyte Colony-Stimulating Factor Is Safe and Well Tolerated Following Allogeneic Transplantation in Patients with Sickle Cell Disease

Niketa C. Shah, MD, Sweta Bhoopatiraju, Allistair Abraham, MD, Eric Jon Anderson, MD, Martin Andreansky, MD, Monica Bhatia, MD, Sonali Chaudhury, MD, Geoff D.E. Cuvelier, MD, Kamar Godder, MD MPH, Michael Grimley, MD, Gregory Hale, MD, Naynesh Kamani, David Jacobsohn, MD, Alexander I. Ngwube, MD, Jodi L. Skiles, MD, Lolie C. Yu, MD, Shalini Shenoy, MD

Blood (2020) 136 (Supplement 1): 33.

https://doi.org/10.1182/blood-2020-142696

Published: 2020

Journal Articles

High-Risk Langerhans Cell Histiocytosis in Infants Exhibits Malignant Features in a Xenograft Model but Responds Durably to Targeted Therapy

Lynn Lee, MD, Mary Christa Krupski, DO, MPH, Jason Clark, MS, Robert B. Lorsbach, MD PhD, Michael Grimley, MD, Matthew Burwinkel, Adam S. Nelson, MBBS, Ashish R Kumar, MD PhD

Blood (2018) 132 (Supplement 1): 4323.

https://doi.org/10.1182/blood-2018-99-119383

Published: 2018

Journal Articles

Gene Therapy for Sickle Cell Anemia Using a Modified Gamma Globin Lentivirus Vector and Reduced Intensity Conditioning Transplant Shows Promising Correction of the Disease Phenotype

Blood (2018) 132 (Supplement 1): 1021.

https://doi.org/10.1182/blood-2018-99-119591

Published: 2018

Journal Articles

Exceptional Responses to Epigenetic Based Therapy in Pediatric and Young Adult Monosomy 7 MDS/AML Patients with and without TP53 Mutations

LaQuita M Jones, DO, Maureen M O'Brien, MD, Erin H. Breese, MD PhD, Karen Burns, MD, Jennifer Mangino, MD, Michael J. Absalon, MD PhD, Javier A. El-Bietar, MD, Michael Grimley, MD, Benjamin Mizukawa, MD, Lynn Lee, MD, John Peter Perentesis, MD, Christine L Phillips, MD

Blood (2017) 130 (Supplement 1): 3895.

https://doi.org/10.1182/blood.V130.Suppl_1.3895.3895

Published: 2017

Journal Articles

T Cell Costimulation Blockade with Abatacept Nearly Eliminates Early Severe Acute Graft Versus Host Disease after HLA-Mismatched (7/8 HLA Matched) Unrelated Donor Transplant, with a Favorable Impact on Disease-Free and Overall Survival

Blood (2017) 130 (Supplement 1): 212.

https://doi.org/10.1182/blood.V130.Suppl_1.212.212

Published: 2017

Journal Articles

Non-Myeloablative Conditioning Targeting Host Immunosuppression Is Successful in Matched Sibling Donor Stem Cell Transplantation for Hemoglobinopathies in Children

Blood (2014) 124 (21): 3873.

https://doi.org/10.1182/blood.V124.21.3873.3873

Published: 2014

Journal Articles

Diagnostic and risk criteria for HSCT-associated thrombotic microangiopathy: a study in children and young adults

Sonata Jodele, Stella M. Davies, Adam Lane, Jane Khoury, Christopher Dandoy, Jens Goebel, Kasiani Myers, Michael Grimley, Jack Bleesing, Javier El-Bietar, Gregory Wallace, Ranjit S. Chima, Zachary Paff, Benjamin L. Laskin

Blood (2014) 124 (4): 645–653.

https://doi.org/10.1182/blood-2014-03-564997

Published: 2014

Includes: Supplemental data

Journal Articles

Adolescents and Young Adults With Hemophagocytic Lymphohistiocytosis Who Undergo Allogeneic Hematopoietic Cell Transplantation Are At Increased Risk Of Mortality Compared To Younger Patients

Shanmuganathan Chandrakasan, MD, Rebecca Marsh, MD, Michael Grimley, MD, Jack Bleesing, MD, PhD, Michael Jordan, MD, Alexandra H. Filipovich, MD

Blood (2013) 122 (21): 2087.

https://doi.org/10.1182/blood.V122.21.2087.2087

Published: 2013

Journal Articles

Transplantation in patients with SCID: mismatched related stem cells or unrelated cord blood?

Blood (2012) 119 (12): 2949–2955.

https://doi.org/10.1182/blood-2011-06-363572

Published: 2012

Includes: Supplemental data

Journal Articles

Defibrotide (DF) In the Treatment of Severe Hepatic Veno-Occlusive Disease (VOD) with Multi-Organ Failure (MOF): Results of a Treatment IND Expanded Access Protocol

Blood (2010) 116 (21): 906.

https://doi.org/10.1182/blood.V116.21.906.906

Published: 2010

Journal Articles

Reduced Intensity Conditioning (RIC) Regimen of Alemtuzmab (A), Fludarabine (F), and Melphalan (M) for Transplantation of Pediatric Non-Malignant Hematologic Disorders (NMHD): Outcome Affected by Stem Cell Source.

Ka Wah Chan, MBBS, Michael Grimley, MD, Veronica H. Jude, MD, Lisa McDonald, MSN, Julie Luke, MSN, Dennise Lim, BA, Shalini Shenoy, MD

Blood (2010) 116 (21): 3490.

https://doi.org/10.1182/blood.V116.21.3490.3490

Published: 2010

Journal Articles

Comparison of Outcomes of Mismatched Related Stem Cell and Unrelated Cord Blood Transplants in Children with Severe T-Cell Deficiencies.

Blood (2009) 114 (22): 664.

https://doi.org/10.1182/blood.V114.22.664.664

Published: 2009

Journal Articles

Evaluation of pentostatin in corticosteroid-refractory chronic graft-versus-host disease in children: a Pediatric Blood and Marrow Transplant Consortium study

David A. Jacobsohn, Andrew L. Gilman, Alfred Rademaker, Brittan Browning, Michael Grimley, Leslie Lehmann, Eneida R. Nemecek, Kimberly Thormann, Kirk R. Schultz, Georgia B. Vogelsang

Blood (2009) 114 (20): 4354–4360.

https://doi.org/10.1182/blood-2009-05-224840

Published: 2009

Includes: Supplemental data

Journal Articles

Reduced-intensity allogeneic transplantation in pediatric patients ineligible for myeloablative therapy: results of the Pediatric Blood and Marrow Transplant Consortium Study ONC0313

Michael A. Pulsipher, Kenneth M. Boucher, Donna Wall, Haydar Frangoul, Michel Duval, Rakesh K. Goyal, Peter J. Shaw, Ann E. Haight, Michael Grimley, Stephan A. Grupp, Morris Kletzel, Richard Kadota

Blood (2009) 114 (7): 1429–1436.

https://doi.org/10.1182/blood-2009-01-196303

Published: 2009

Includes: Supplemental data

Journal Articles

Clinical and Cost Outcomes of Double Umbilical Cord Blood Versus Bone Marrow and Peripheral Blood Unrelated Hematopoietic Stem Cell Transplants.

Guillermo López-González, Charles F. LeMaistre, MD, Carlos Bachier, MD, Brad Smith, PhD, Ka Wah Chan, MBBS, Michael Grimley, MD, Wilma Cain, Elina Delgado, Shawn Kaleel, Paul Shaughnessy, MD

Blood (2008) 112 (11): 967.

https://doi.org/10.1182/blood.V112.11.967.967

Published: 2008

NARROW

Preliminary Results of a Phase 2a Clinical Trial to Evaluate Safety, Tolerability and Antiviral Activity of Intravenous Brincidofovir (BCV IV) in Immunocompromised Patients with Adenovirus Infection

Higher abatacept exposure after transplant decreases acute GVHD risk without increasing adverse events

Safety and Efficacy of Aru-1801 in Patients with Sickle Cell Disease: Early Results from the Phase 1/2 Momentum Study of a Modified Gamma Globin Gene Therapy and Reduced Intensity Conditioning

Early Results from a Phase 1/2 Study of Aru-1801 Gene Therapy for Sickle Cell Disease (SCD): Manufacturing Process Enhancements Improve Efficacy of a Modified Gamma Globin Lentivirus Vector and Reduced Intensity Conditioning Transplant

A Multi-Center Case Series, Systematic Review and Meta-Analysis of Neonatal Hemophagocytic Lymphohistiocytosis

Granulocyte Colony-Stimulating Factor Is Safe and Well Tolerated Following Allogeneic Transplantation in Patients with Sickle Cell Disease

High-Risk Langerhans Cell Histiocytosis in Infants Exhibits Malignant Features in a Xenograft Model but Responds Durably to Targeted Therapy

Gene Therapy for Sickle Cell Anemia Using a Modified Gamma Globin Lentivirus Vector and Reduced Intensity Conditioning Transplant Shows Promising Correction of the Disease Phenotype

Exceptional Responses to Epigenetic Based Therapy in Pediatric and Young Adult Monosomy 7 MDS/AML Patients with and without TP53 Mutations

T Cell Costimulation Blockade with Abatacept Nearly Eliminates Early Severe Acute Graft Versus Host Disease after HLA-Mismatched (7/8 HLA Matched) Unrelated Donor Transplant, with a Favorable Impact on Disease-Free and Overall Survival

Non-Myeloablative Conditioning Targeting Host Immunosuppression Is Successful in Matched Sibling Donor Stem Cell Transplantation for Hemoglobinopathies in Children

Diagnostic and risk criteria for HSCT-associated thrombotic microangiopathy: a study in children and young adults

Adolescents and Young Adults With Hemophagocytic Lymphohistiocytosis Who Undergo Allogeneic Hematopoietic Cell Transplantation Are At Increased Risk Of Mortality Compared To Younger Patients

Transplantation in patients with SCID: mismatched related stem cells or unrelated cord blood?

Defibrotide (DF) In the Treatment of Severe Hepatic Veno-Occlusive Disease (VOD) with Multi-Organ Failure (MOF): Results of a Treatment IND Expanded Access Protocol

Reduced Intensity Conditioning (RIC) Regimen of Alemtuzmab (A), Fludarabine (F), and Melphalan (M) for Transplantation of Pediatric Non-Malignant Hematologic Disorders (NMHD): Outcome Affected by Stem Cell Source.

Comparison of Outcomes of Mismatched Related Stem Cell and Unrelated Cord Blood Transplants in Children with Severe T-Cell Deficiencies.

Evaluation of pentostatin in corticosteroid-refractory chronic graft-versus-host disease in children: a Pediatric Blood and Marrow Transplant Consortium study

Reduced-intensity allogeneic transplantation in pediatric patients ineligible for myeloablative therapy: results of the Pediatric Blood and Marrow Transplant Consortium Study ONC0313

Clinical and Cost Outcomes of Double Umbilical Cord Blood Versus Bone Marrow and Peripheral Blood Unrelated Hematopoietic Stem Cell Transplants.

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American Society of Hematology

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American Society of Hematology

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