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Journal Articles

Long Term Follow-up after Treatment with Allogeneic Off-the-Shelf CAR T Cell Therapy for Relapsed or Refractory B-Cell Malignancies

Sanam Shahid, Georgia C Flynn, Audrey Mauguen, Jennifer Bieler, Susan E Prockop, Andromachi Scaradavou, Jaap Jan Boelens, Craig S Sauter, Miguel-Angel Perales, Sergio A. Giralt, Xiuyan Wang, Isabelle Riviere, Michel Sadelain, Renier Brentjens, Nancy A Kernan, Richard J O'Reilly, Kevin J Curran

Blood (2023) 142 (Supplement 1): 3476.

https://doi.org/10.1182/blood-2023-180753

Published: 2023

Journal Articles

Rabbit Anti-Thymocyte Globulin Exposure (rATG) in CD34+ Selected Hematopoietic Cell Transplantation and Its Impact on Immune Reconstitution and Outcomes in Children and Adults

Blood (2020) 136 (Supplement 1): 30–31.

https://doi.org/10.1182/blood-2020-136341

Published: 2020

Journal Articles

Toxicity and response after CD19-specific CAR T-cell therapy in pediatric/young adult relapsed/refractory B-ALL

Blood (2019) 134 (26): 2361–2368.

https://doi.org/10.1182/blood.2019001641

Published: 2019

Includes: Supplemental data

Journal Articles

Allogeneic CD34-Selected HSCT Following CAR T-Cells Is Associated with Low TRM and Favorable OS in Pediatric/Young Adult Patients with Relapsed/Refractory B-ALL

Vanessa Fabrizio, MD, Farid Boulad, MD, Maria I. Cancio, MD, Meghan A. Higman, MD PhD, Steven P. Margossian, MD PhD, Audrey Mauguen, PhD, Susan Prockop, MD, Andromachi Scaradavou, MD, Niketa C. Shah, MD, Barbara Spitzer, MD, Nick Yeager, Nancy A. Kernan, Richard O'Reilly, MD, Jaap Jan Boelens, MD PhD, Kevin J. Curran, MD

Blood (2019) 134 (Supplement_1): 4582.

https://doi.org/10.1182/blood-2019-121767

Published: 2019

Journal Articles

Evaluation of Cord Blood (CB) Unit TNC & CD34+ Cell Content & Donor-Recipient High-Resolution 8 HLA-Allele Match By Patient Ancestry: An Evaluation of 513 CB Units in a Racially & Ethnically Diverse Population of Adults with Hematologic Malignancies

Christopher Mazis, BS, Ioannis Politikos, MD, Sean M Devlin, PhD, Molly Maloy, MS, Eric Davis, MPH, Candice Cooper, Melissa Nhaissi, MPH, Beth Suri, Deborah Wells, Sergio Giralt, MD, Gunjan L. Shah, MD, Marcel R.M. van den Brink, MD PhD, Nancy A. Kernan, Andromachi Scaradavou, MD, Juliet Barker, MBBS

Blood (2018) 132 (Supplement 1): 3342.

https://doi.org/10.1182/blood-2018-99-116598

Published: 2018

Journal Articles

Incidence of Post-Hematopoietic Stem Cell Transplantation (HSCT) Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) without Hyperbilirubinemia at Diagnosis and Efficacy of Defibrotide in an Expanded-Access Program

Selim Corbacioglu, MD, Nancy A. Kernan, Antonio Pagliuca, Robert Ryan, William Tappe, Paul Richardson

Blood (2018) 132 (Supplement 1): 2080.

https://doi.org/10.1182/blood-2018-99-117173

Published: 2018

Journal Articles

Adoptive T-Cell Therapy with 3 rd Party CMV-pp65-Specific CTLs for CMV Viremia and Disease Arising after Allogeneic Hematopoietic Stem Cell Transplant

Susan Prockop, MD, Ekaterina Doubrovina, MD PhD, Irene Rodriguez-Sanchez, Aisha N. Hasan, MD, Juliet Barker, MBBS, H.R. Castro-Malaspina, MD, Parastoo B. Dahi, MD, Sergio A. Giralt, MD, Boglarka Gyurkocza, MD, Nancy A. Kernan, MD, Guenther Koehne, MDPhD, Esperanza B. Papadopoulos, MD, Doris Ponce, MD, Craig S. Sauter, MD, Virginia Escobedo, RN, Victoria Szenes, PNP, Karim Baroudy, BS, Alison Slocum, MA, Richard J. O'Reilly, MD

Blood (2017) 130 (Supplement 1): 747.

https://doi.org/10.1182/blood.V130.Suppl_1.747.747

Published: 2017

Journal Articles

Pooled Analysis of Day +100 Survival for Defibrotide-Treated Patients with Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) and Ventilator or Dialysis Dependence Following Hematopoietic Stem Cell Transplantation (HSCT)

Paul G Richardson, MD, Angela R. Smith, MD MS, Nancy A. Kernan, MD, Joseph H. Antin, MD, Leslie Lehmann, MD, Robert J. Ryan, Robin L. Hume, MS, William Martin Tappe, MD, Stephan A Grupp, MD PhD

Blood (2017) 130 (Supplement 1): 1946.

https://doi.org/10.1182/blood.V130.Suppl_1.1946.1946

Published: 2017

Journal Articles

Efficacy and Safety of Defibrotide in Pediatric Patients with Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) after Hematopoietic Stem Cell Transplantation (HSCT): Final Results from the Expanded-Access Program

Nancy A. Kernan, MD, Angela R. Smith, MD MS, Brandon Triplett, MD, Leslie Lehmann, MD, Robert J. Ryan, Wei Liang, Robin L. Hume, MS, William Martin Tappe, MD, Stephan A Grupp, MD PhD

Blood (2017) 130 (Supplement 1): 1948.

https://doi.org/10.1182/blood.V130.Suppl_1.1948.1948

Published: 2017

Journal Articles

High Dose Cyclophosphamide and Pre-Treatment Disease Burden Dictate Response and Survival in a Multicenter Clinical Trial Using CD19-Specific CAR T Cells for Relapsed/Refractory B-ALL

Blood (2017) 130 (Supplement 1): 1326.

https://doi.org/10.1182/blood.V130.Suppl_1.1326.1326

Published: 2017

Journal Articles

Adults Receiving Defibrotide for the Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) after Hematopoietic Stem Cell Transplantation (HSCT): Final Results from the Expanded-Access Program

Paul G Richardson, MD, Joseph H. Antin, MD, Sergio A. Giralt, MD, Robert J. Ryan, Wei Liang, Robin L. Hume, MS, William Martin Tappe, MD, Nancy A. Kernan, MD

Blood (2017) 130 (Supplement 1): 3225.

https://doi.org/10.1182/blood.V130.Suppl_1.3225.3225

Published: 2017

Journal Articles

Radiation-free, alternative-donor HCT for Fanconi anemia patients: results from a prospective multi-institutional study

Parinda A. Mehta, Stella M. Davies, Thomas Leemhuis, Kasiani Myers, Nancy A. Kernan, Susan E. Prockop, Andromachi Scaradavou, Richard J. O’Reilly, David A. Williams, Leslie Lehmann, Eva Guinan, David Margolis, K. Scott Baker, Adam Lane, Farid Boulad

Blood (2017) 129 (16): 2308–2315.

https://doi.org/10.1182/blood-2016-09-743112

Published: 2017

Journal Articles

Selection of Unrelated Allogeneic Hematopoietic Cell Donors Based on KIR3DL1 Allotypes Is Feasible and Results in Improved Disease-Free Survival in Transplant Recipients with MDS and AML

Brian C. Shaffer, MD, Glenn Heller, PhD, Jean-Benoit Le Luduec, PhD, Jack Vahradian, Miguel Perales, MD, Sergio A. Giralt, MD, Roni Tamari, MD, Boglarka Gyurkocza, MD, Ann A. Jakubowski, MD PhD, E B Papadopoulos, MD, Jeanette E Boudreau, BSc, PhD, Nancy A. Kernan, MD, Katharine C. Hsu, MD PhD

Blood (2016) 128 (22): 990.

https://doi.org/10.1182/blood.V128.22.990.990

Published: 2016

Journal Articles

Allogeneic Hematopoietic Stem Cell Transplant with Ablative Conditioning Is Associated with Favorable Outcomes in Patients with Mixed Phenotype Acute Leukemia

Bartlomiej M Getta, MBBS, Junting Zheng, Martin S. Tallman, MD, Jae H. Park, MD, Eytan M. Stein, MD, Mikhail Roshal, MD PhD, Esperanza B. Papadopoulos, MD, Nancy A. Kernan, MD, Peter G. Steinherz, MD, Richard J. O'Reilly, MD, Miguel-Angel Perales, MD, Sergio A. Giralt, MD, Brian C. Shaffer, MD

Blood (2016) 128 (22): 3487.

https://doi.org/10.1182/blood.V128.22.3487.3487

Published: 2016

Journal Articles

Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) Post-Hematopoietic Stem Cell Transplantation (HSCT) in Patients with Acute Leukemias: A Subgroup Analysis from the Defibrotide Expanded-Access Program

Paul G. Richardson, MD, Angela R. Smith, MD, Brandon M. Triplett, MD, Nancy A. Kernan, MD, Stephan A. Grupp, MD PhD, Joseph H. Antin, MD, Leslie Lehmann, MD, Wei Liang, PhD, Robin Hume, MS, William Tappe, MD, Robert J. Soiffer, MD

Blood (2016) 128 (22): 3412.

https://doi.org/10.1182/blood.V128.22.3412.3412

Published: 2016

Journal Articles

Third Party CMV-Specific Cytotoxic T Cells for Treatment of Antiviral Resistant CMV Infection after Hematopoietic Stem Cell Transplant

Susan Prockop, MD, Ekaterina Doubrovina, MD PhD, Aisha N Hasan, MD, Parastoo B Dahi, MD, Sergio Giralt, MD, Guenther Koehne, MD PhD, Nancy A. Kernan, MD, Esperanza B Papadopoulos, MD, Rachel Lehrman, Irene Rodriguez-Sanchez, Richard J. O'Reilly, MD

Blood (2016) 128 (22): 61.

https://doi.org/10.1182/blood.V128.22.61.61

Published: 2016

Journal Articles

Despite Increasing Size of Unrelated Donor (URD) Registries and the Global Cord Blood (CB) Inventory Racial Disparities in Access to URD and CB Grafts Persist: A Prospective 10 Year Analysis of 1,112 Patients

Kirsten Boughan, MD, Parastoo B. Dahi, MD, Sean Devlin, PhD, Courtney Byam, BS, CHTC, Yeon Yoo, BS, Christopher Mazis, BS, Eric Davis, CHTC, Melissa Nhaissi, MPH, Jennifer Paulson, MBS, CHTC, Deborah Wells, MA, CHTC, Candice Cooper, BS, Doris M Ponce, MD, Sergio Giralt, MD, Esperanza B. Papadopoulos, MD, Nancy A. Kernan, MD, Andromachi Scaradavou, MD, Juliet N. Barker, MBBS (Hons)

Blood (2016) 128 (22): 821.

https://doi.org/10.1182/blood.V128.22.821.821

Published: 2016

Journal Articles

Timing of Initiation of Defibrotide Post-Diagnosis of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome Post-Hematopoietic Stem Cell Transplantation: Exploratory Age-Group Analysis from an Expanded Access Study

Stephan A. Grupp, MD PhD, Angela R. Smith, MD, Brandon M. Triplett, MD, Nancy A. Kernan, MD, Joseph H. Antin, MD, Leslie Lehmann, MD, Wei Liang, PhD, Robin Hume, MS, William Tappe, MD, Paul G. Richardson, MD

Blood (2016) 128 (22): 66.

https://doi.org/10.1182/blood.V128.22.66.66

Published: 2016

Journal Articles

Impact on Outcomes of Baseline Bilirubin in Patients with Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome Receiving Defibrotide Treatment: A Post-Hoc Analysis

Blood (2016) 128 (22): 2213.

https://doi.org/10.1182/blood.V128.22.2213.2213

Published: 2016

Journal Articles

Phase 3 trial of defibrotide for the treatment of severe veno-occlusive disease and multi-organ failure

Blood (2016) 127 (13): 1656–1665.

https://doi.org/10.1182/blood-2015-10-676924

Published: 2016

Includes: Supplemental data

NARROW

Long Term Follow-up after Treatment with Allogeneic Off-the-Shelf CAR T Cell Therapy for Relapsed or Refractory B-Cell Malignancies

Rabbit Anti-Thymocyte Globulin Exposure (rATG) in CD34+ Selected Hematopoietic Cell Transplantation and Its Impact on Immune Reconstitution and Outcomes in Children and Adults

Toxicity and response after CD19-specific CAR T-cell therapy in pediatric/young adult relapsed/refractory B-ALL

Allogeneic CD34-Selected HSCT Following CAR T-Cells Is Associated with Low TRM and Favorable OS in Pediatric/Young Adult Patients with Relapsed/Refractory B-ALL

Evaluation of Cord Blood (CB) Unit TNC & CD34+ Cell Content & Donor-Recipient High-Resolution 8 HLA-Allele Match By Patient Ancestry: An Evaluation of 513 CB Units in a Racially & Ethnically Diverse Population of Adults with Hematologic Malignancies

Incidence of Post-Hematopoietic Stem Cell Transplantation (HSCT) Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) without Hyperbilirubinemia at Diagnosis and Efficacy of Defibrotide in an Expanded-Access Program

Adoptive T-Cell Therapy with 3 rd Party CMV-pp65-Specific CTLs for CMV Viremia and Disease Arising after Allogeneic Hematopoietic Stem Cell Transplant

Pooled Analysis of Day +100 Survival for Defibrotide-Treated Patients with Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) and Ventilator or Dialysis Dependence Following Hematopoietic Stem Cell Transplantation (HSCT)

Efficacy and Safety of Defibrotide in Pediatric Patients with Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) after Hematopoietic Stem Cell Transplantation (HSCT): Final Results from the Expanded-Access Program

High Dose Cyclophosphamide and Pre-Treatment Disease Burden Dictate Response and Survival in a Multicenter Clinical Trial Using CD19-Specific CAR T Cells for Relapsed/Refractory B-ALL

Adults Receiving Defibrotide for the Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) after Hematopoietic Stem Cell Transplantation (HSCT): Final Results from the Expanded-Access Program

Radiation-free, alternative-donor HCT for Fanconi anemia patients: results from a prospective multi-institutional study

Selection of Unrelated Allogeneic Hematopoietic Cell Donors Based on KIR3DL1 Allotypes Is Feasible and Results in Improved Disease-Free Survival in Transplant Recipients with MDS and AML

Allogeneic Hematopoietic Stem Cell Transplant with Ablative Conditioning Is Associated with Favorable Outcomes in Patients with Mixed Phenotype Acute Leukemia

Treatment of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) Post-Hematopoietic Stem Cell Transplantation (HSCT) in Patients with Acute Leukemias: A Subgroup Analysis from the Defibrotide Expanded-Access Program

Third Party CMV-Specific Cytotoxic T Cells for Treatment of Antiviral Resistant CMV Infection after Hematopoietic Stem Cell Transplant

Despite Increasing Size of Unrelated Donor (URD) Registries and the Global Cord Blood (CB) Inventory Racial Disparities in Access to URD and CB Grafts Persist: A Prospective 10 Year Analysis of 1,112 Patients

Timing of Initiation of Defibrotide Post-Diagnosis of Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome Post-Hematopoietic Stem Cell Transplantation: Exploratory Age-Group Analysis from an Expanded Access Study

Impact on Outcomes of Baseline Bilirubin in Patients with Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome Receiving Defibrotide Treatment: A Post-Hoc Analysis

Phase 3 trial of defibrotide for the treatment of severe veno-occlusive disease and multi-organ failure

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American Society of Hematology

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American Society of Hematology

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