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Jaap Jan Boelens
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Journal Articles

T- and B-Cell Subset Reconstitution As Predictor of Relapse in Pediatric and Young Adult Allo-Hematopoietic Cell Transplantation Patients

Devin McAvoy, Matthew Thomsen, Evangelos Ntrivalas, Elizabeth Klein, Kinga K. Hosszu, Jaap Jan Boelens, Joseph H. Oved
Journal: Blood
Blood (2024) 144 (Supplement 1): 2175.
https://doi.org/10.1182/blood-2024-208766
Published: 2024
Journal Articles

Cerebral Hemodynamics Improve in Adults with Sickle Cell Disease after Gene Therapy

Akshay Sharma, Jane S Hankins, Jaap Jan Boelens, Maria Cancio, Radhika Peddinti, Lawrence Rispoli, Sarah Sloan, Sarah DiDominick Costa, Sharon Peled, Andrea Wiethoff, James LaBelle
Journal: Blood
Blood (2024) 144 (Supplement 1): 4953.
https://doi.org/10.1182/blood-2024-203184
Published: 2024
Journal Articles

Rabbit Antithymocyte (rATG) Exposure and Outcomes after Hematopoietic Cell Transplantation: A Real World Experience from BMT CTN 1202

Madhavi Lakkaraja, Audrey Mauguen, Kinga K Hosszu, Devin McAvoy, Valerie Stewart, Gabrielle Schmidt, John Levine, Miguel-Angel Perales, Sergio A. Giralt, K. Scott Baker, Jaap Jan Boelens
Journal: Blood
Blood (2023) 142 (Supplement 1): 111.
https://doi.org/10.1182/blood-2023-182352
Published: 2023
Journal Articles

Radiation and Busulfan-Free Hematopoietic Stem Cell Transplantation Using Briquilimab (JSP191) Anti-CD117 Antibody-Conditioning, Transient Immunosuppression and TCRαβ + T-Cell/CD19 + B-Cell Depleted Haploidentical Grafts in Patients with Fanconi Anemia

Rajni Agarwal, Alice Bertaina, Charmaine Fay Soco, Gopin Saini, Nivedita Kunte, Lyndsie Hiroshima, Yan Yi Chan, Hana Willner, Mark L. Krampf, Rofida Nofal, Giulia Barbarito, Sushmita Sen, Matthias Felber, Maite Van Hentenryck, Emily Walck, Amelia Scheck, Supawat Thongthip, Aaron C. Logan, Kirstin Dougall, Ali Bouge, Jaap Jan Boelens, Janel R. Long-Boyle, Irving L. Weissman, Judith Shizuru, Wendy W Pang, Kenneth I. Weinberg, Robertson Parkman, Maria-Grazia Roncarolo, Matthew Porteus, Agnieszka Czechowicz
Journal: Blood
Blood (2023) 142 (Supplement 1): 229.
https://doi.org/10.1182/blood-2023-178400
Published: 2023
Journal Articles

Long Term Follow-up after Treatment with Allogeneic Off-the-Shelf CAR T Cell Therapy for Relapsed or Refractory B-Cell Malignancies

Sanam Shahid, Georgia C Flynn, Audrey Mauguen, Jennifer Bieler, Susan E Prockop, Andromachi Scaradavou, Jaap Jan Boelens, Craig S Sauter, Miguel-Angel Perales, Sergio A. Giralt, Xiuyan Wang, Isabelle Riviere, Michel Sadelain, Renier Brentjens, Nancy A Kernan, Richard J O'Reilly, Kevin J Curran
Journal: Blood
Blood (2023) 142 (Supplement 1): 3476.
https://doi.org/10.1182/blood-2023-180753
Published: 2023
Journal Articles

Effectiveness and Safety of Rabbit Anti-Thymocyte Globulin Versus Non-Anti-Thymocyte Globulin Regimens for Graft-Versus-Host Disease Prophylaxis: A Systematic Review and Meta-Analysis

Jaap Jan Boelens, Andrew Bodiford, Francois Bourhis, Marie Baccara-Dinet, Lauren Rota, Michaela Lysikova
Journal: Blood
Blood (2023) 142 (Supplement 1): 4992.
https://doi.org/10.1182/blood-2023-181836
Published: 2023
Journal Articles

TNC/Kg and CD34+/Kg Cell Dose Impact on Patient Engraftment after Allogeneic Transplant with Conventional Bone Marrow; Better Predictability of Graft Content Needed

Eric Davis, Elise Feuer, Candice Rapoport, Stephanie Lobaugh, Sean M. Devlin, Anne Archer, Stephanie Chinapen, Jacob Federman, Amanda Kelly, Elizabeth Klein, Melissa Nhaissi, Deborah Wells, Juliet N Barker, Esperanza B. Papadopoulos, Andromachi Scaradavou, Jaap Jan Boelens, Miguel-Angel Perales, Elena Maryamchik, Roni Tamari
Journal: Blood
Blood (2023) 142 (Supplement 1): 113.
https://doi.org/10.1182/blood-2023-190940
Published: 2023
Journal Articles

Treatment of Individuals with Severe Sickle Cell Disease with OTQ923, an Autologous, Ex Vivo , CRISPR/Cas9-Edited, CD34+ Hematopoietic Stem and Progenitor Cell Product, Leads to Durable Engraftment and Fetal Hemoglobin Induction

Akshay Sharma, Jaap Jan Boelens, Maria I. Cancio, Jane Hankins, Prafulla A Bhad, Andrew Lewandowski, Xiaojun Zhao, Shripad Chitnis, Radhika Peddinti, Yan Zheng, Neena Kapoor, Fabio Ciceri, Jianping Yuan, Vionnie W. Yu, Susan C. Stevenson, Serena De Vita, James LaBelle
Journal: Blood
Blood (2022) 140 (Supplement 1): 1906–1908.
https://doi.org/10.1182/blood-2022-166254
Published: 2022
Journal Articles

Bodyweight and Absolute Lymphocyte Count Based Dosing of Rabbit Anti-Thymocyte Globulin Results in Early CD4+ Immune Reconstitution in Patients with Inborn Errors of Metabolism Undergoing Umbilical Cord Blood Transplantation

Daniel Drozdov, Susie L. Long, Ashish O. Gupta, Troy C. Lund, Jaap Jan Boelens, Paul J. Orchard
Journal: Blood
Blood (2022) 140 (Supplement 1): 4797–4798.
https://doi.org/10.1182/blood-2022-158585
Published: 2022
Journal Articles

Early intestinal microbial features are associated with CD4 T-cell recovery after allogeneic hematopoietic transplant

Clinical Trials & Observations
Oriana Miltiadous, Nicholas R. Waters, Hana Andrlová, Anqi Dai, Chi L. Nguyen, Marina Burgos da Silva, Sarah Lindner, John Slingerland, Paul Giardina, Annelie Clurman, Gabriel K. Armijo, Antonio L. C. Gomes, Madhavi Lakkaraja, Peter Maslak, Michael Scordo, Roni Shouval, Anna Staffas, Richard O’Reilly, Ying Taur, Susan Prockop, Jaap Jan Boelens, Sergio Giralt, Miguel-Angel Perales, Sean M. Devlin, Jonathan U. Peled, Kate A. Markey, Marcel R. M. van den Brink
Journal: Blood
Blood (2022) 139 (18): 2758–2769.
https://doi.org/10.1182/blood.2021014255
Published: 2022
Includes: Supplemental data
Journal Articles

Harmonization, biomarkers, disease risk index

Jaap Jan Boelens
Journal: Blood
Blood (2021) 137 (7): 874–875.
https://doi.org/10.1182/blood.2020009862
Published: 2021
Journal Articles

CD4 + T-cell reconstitution predicts survival outcomes after acute graft-versus-host-disease: a dual-center validation

Clinical Trials & Observations
Coco de Koning, Susan Prockop, Ichelle van Roessel, Nancy Kernan, Elizabeth Klein, Jurgen Langenhorst, Celina Szanto, Mirjam Belderbos, Marc Bierings, Farid Boulad, Dorine Bresters, Maria Cancio, Kevin Curran, Wouter Kollen, Richard O’Reilly, Andromachi Scaradavou, Barbara Spitzer, Birgitta Versluijs, Alwin Huitema, Caroline Lindemans, Stefan Nierkens, Jaap Jan Boelens
Journal: Blood
Blood (2021) 137 (6): 848–855.
https://doi.org/10.1182/blood.2020007905
Published: 2021
Includes: Supplemental data
Journal Articles

Rabbit Anti-Thymocyte Globulin Exposure (rATG) in CD34+ Selected Hematopoietic Cell Transplantation and Its Impact on Immune Reconstitution and Outcomes in Children and Adults

Madhavi Lakkaraja, MDMPH, Michael Scordo, MD, Audrey Mauguen, PhD, Christina Cho, MD, Sean Devlin, PhD, Scott T Avecilla, MDPhD, Farid Boulad, MD, Maria I. Cancio, MD, Kevin J. Curran, MD, Ann A. Jakubowski, MDPhD, Nancy A. Kernan, Andrew L. Kung, MD PhD, Richard J O'Reilly, MD, Esperanza B. Papadopoulos, MD, Susan Prockop, MD, Ichelle Roessel, Josel D Ruiz, MPH, Andromachi Scaradavou, MD, Brian C. Shaffer, MD, Gunjan Shah, MD, Barbara Spitzer, MD, Roni Tamari, MD, Sergio A. Giralt, MD, Miguel-Angel Perales, MD, Jaap Jan Boelens, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30–31.
https://doi.org/10.1182/blood-2020-136341
Published: 2020
Journal Articles

Comparison of Fixed Vs ALC-Based Doses of Thymoglobulin ® (ATG) in Pediatric Patients with Acute Leukemia Given αβhaplo-HSCT: Impact on Immune Reconstitution at Day 90

Giulia Barbarito, David C Shyr, MD, Gopin Saini, MBBS, Linda Oppizzi, BS, Y. Lucy Liu, MDPhD, Rachana Patil, MS, Jaap-Jan Boelens, MD PhD, Alice Bertaina, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16.
https://doi.org/10.1182/blood-2020-140461
Published: 2020
Journal Articles

Toxicity and response after CD19-specific CAR T-cell therapy in pediatric/young adult relapsed/refractory B-ALL

Clinical Trials & Observations
Kevin J. Curran, Steven P. Margossian, Nancy A. Kernan, Lewis B. Silverman, David A. Williams, Neerav Shukla, Rachel Kobos, Christopher J. Forlenza, Peter Steinherz, Susan Prockop, Farid Boulad, Barbara Spitzer, Maria I. Cancio, Jaap Jan Boelens, Andrew L. Kung, Yasmin Khakoo, Victoria Szenes, Jae H. Park, Craig S. Sauter, Glenn Heller, Xiuyan Wang, Brigitte Senechal, Richard J. O’Reilly, Isabelle Riviere, Michel Sadelain, Renier J. Brentjens
Journal: Blood
Blood (2019) 134 (26): 2361–2368.
https://doi.org/10.1182/blood.2019001641
Published: 2019
Includes: Supplemental data
Journal Articles

Allogeneic CD34-Selected HSCT Following CAR T-Cells Is Associated with Low TRM and Favorable OS in Pediatric/Young Adult Patients with Relapsed/Refractory B-ALL

Vanessa Fabrizio, MD, Farid Boulad, MD, Maria I. Cancio, MD, Meghan A. Higman, MD PhD, Steven P. Margossian, MD PhD, Audrey Mauguen, PhD, Susan Prockop, MD, Andromachi Scaradavou, MD, Niketa C. Shah, MD, Barbara Spitzer, MD, Nick Yeager, Nancy A. Kernan, Richard O'Reilly, MD, Jaap Jan Boelens, MD PhD, Kevin J. Curran, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4582.
https://doi.org/10.1182/blood-2019-121767
Published: 2019
Journal Articles

Related and Unrelated Donor Transplantation for β Thalassemia Major: Results of an International Survey

Chunfu Li, MD, Vikram Mathews, MD, Biju George, DM, Soyoung Kim, Kyle Hebert, Hua Jiang, MD, Changgang Li, MD, Yiping Zhu, Daniel A Keesler, BS, Rajni Agarwal, MD, Jaap Jan Boelens, MD PhD, Christopher C. Dvorak, MD, Jeffery Auletta, MD, Rakesh Kumar Goyal, MBBS,MDMRCP, Rabi Hanna, MD, Kimberly A. Kasow, DO, David Margolis, MD, Shalini Shenoy, MD, Mark C. Walters, MD, Mary Eapen, MBBS, MS
Journal: Blood
Blood (2018) 132 (Supplement 1): 308.
https://doi.org/10.1182/blood-2018-99-111152
Published: 2018
Journal Articles

Rapid and Robust CD4+ and CD8+ T-, NK-, B- and Monocyte Cell Reconstitution after Nicotinamide-Expanded Cord Blood Transplantation

Jaap Jan Boelens, MD PhD, Coco de Koning, Mitchell E. Horwitz, MD, Guillermo Sanz, Madan Jagasia, MD MS, John E. Wagner, MD, Patrick J. Stiff, MD, Rabi Hanna, MD, Daniela Cilloni, MD PhD, Stefan Nierkens, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2123.
https://doi.org/10.1182/blood-2018-99-116700
Published: 2018
Journal Articles

First Results of a Prospective I/II Clinical Trial in Adult Patients Using TCR Alpha/Beta Depleted Stem Cell Transplantation from Matched Related and Unrelated Donors

Moniek De Witte, MD PhD, Anna Van Rhenen, MD PhD, Geerte Van Sluis, MD PhD, Rick Admiraal, MD PhD, Lotte van der Wagen, MD, Eefke J. Petersen, MD PhD, Reinier Raymakers, MD PhD, Monique C Minnema, MD PhD, Anke Janssen, MD, Kasper Westinga, BSc, Constantijn J.M. Halkes, MD, J.H. Frederik Falkenburg, MD PhD, Jaap Jan Boelens, MD PhD, Jurgen Kuball, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2164.
https://doi.org/10.1182/blood-2018-99-112758
Published: 2018
Journal Articles

Cord Blood Regulatory T Cells for Prevention of Graft Versus Host Disease

Joshua Kellner, Stefan O. Ciurea, Amanda L. Olson, MD, Yago Nieto, MD PhD, Borje S Andersson, MDPhD, Joseph David Khoury, MD, Richard E. Champlin, MD, Stefan Nierkens, PhD, Jaap Jan Boelens, MD PhD, Bruce Blazar, MD, Simrit Parmar, MBBS
Journal: Blood
Blood (2017) 130 (Supplement 1): 3246.
https://doi.org/10.1182/blood.V130.Suppl_1.3246.3246
Published: 2017