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Journal Articles

T-allo10 Immunotherapy Results in Enhanced Early Immune Reconstitution and Reduced GvHD with Excellent Clinical Outcomes Post Αβ-Depleted HSCT in Pediatric and Young Adult Hematologic Malignancy Patients

Alice Bertaina, Rosa Bacchetta, Alma-Martina Cepika, David C Shyr, Giulia Barbarito, Linda Oppizzi, Pauline Chen, Gopin Saini, Jennifer Lee, Karen Kristovich, Rajni Agarwal, Orly Klein, Kathryn Melsop, Keri Tate, Matthew Porteus, Maria Grazia Roncarolo

Blood (2024) 144 (Supplement 1): 3525.

https://doi.org/10.1182/blood-2024-194276

Published: 2024

Journal Articles

Evaluation of Bone Marrow in Fanconi Anemia Patients Treated with Briquilimab Antibody-Based Conditioning and TCRαβ + T-Cell/CD19 + B-Cell Depleted Haploidentical Grafts

Charmaine Fay Soco, Mark R. Krampf, Yan Yi Chan, Hana Hoang, Nivedita Kunte, Gopin Saini, Kenneth I. Weinberg, Robertson Parkman, Alice Bertaina, Rajni Agarwal, Matthew Porteus, Agnieszka D. Czechowicz

Blood (2024) 144 (Supplement 1): 2015.

https://doi.org/10.1182/blood-2024-206381

Published: 2024

Journal Articles

Towards Automated Engineering of Donor-Derived T Lymphocytes into CRISPR/Cas9-Mediated CAR T Cells in a Closed-System

Aluya Richard Oseghale, Alice Bertaina, Matthew Porteus

Blood (2023) 142 (Supplement 1): 4826.

https://doi.org/10.1182/blood-2023-189883

Published: 2023

Journal Articles

Radiation and Busulfan-Free Hematopoietic Stem Cell Transplantation Using Briquilimab (JSP191) Anti-CD117 Antibody-Conditioning, Transient Immunosuppression and TCRαβ + T-Cell/CD19 + B-Cell Depleted Haploidentical Grafts in Patients with Fanconi Anemia

Blood (2023) 142 (Supplement 1): 229.

https://doi.org/10.1182/blood-2023-178400

Published: 2023

Journal Articles

Targeting of CD25+ Activated T Cells in Gvhd-Associated Marrow Suppression and Cytopenias

Tami D. John, Laura Valine, Giulia Barbarito, Hye-Sook Kwon, Sally Arai, Beth Martin-Kool, Radhika Kumari, Judith Shizuru, Jean S. Oak, Robertson Parkman, Alice Bertaina, Kenneth I. Weinberg

Blood (2023) 142 (Supplement 1): 7033.

https://doi.org/10.1182/blood-2023-190968

Published: 2023

Journal Articles

Extracellular Release of Damaged Mitochondria Induced By Cytotoxic Conditioning Exacerbates Graft-Versus-Host Disease

Vijith Vijayan, Hao Yan, Juliane Lohmeyer, Kaylin Prentiss, Rachana Patil, Giulia Barbarito, Ivan Lopez, Aly Elezaby, Kolten Peterson, Jeanette Baker, Nicolai Ostberg, Alice Bertaina, Robert S. Negrin, Daria Mochly-Rosen, Kenneth I. Weinberg, Bereketeab Haileselassie

Blood (2023) 142 (Supplement 1): 2051.

https://doi.org/10.1182/blood-2023-179456

Published: 2023

Journal Articles

Believe in haploidentical HSCT: less is better

Alice Bertaina

Blood (2022) 140 (24): 2523–2524.

https://doi.org/10.1182/blood.2022017535

Published: 2022

Journal Articles

Novel Humanized Loss-of-Function NF1 Mouse Model of Juvenile Myelomonocytic Leukemia

Roshani Sinha, Rachana Patil, Rosa Romano, Esmond Lee, Zhenyu Yao, Y. Lucy Liu, Matthew H. Porteus, Alice Bertaina

Blood (2022) 140 (Supplement 1): 9765–9766.

https://doi.org/10.1182/blood-2022-167413

Published: 2022

Journal Articles

The Determinative Role of Hematopoietic Stem and Progenitor Cell Graft Composition on the Engraftment Kinetics after HSCT

Giulia Barbarito, Beruh Dejene, Gopin Saini, Rachana Patil, David C. Shyr, Robertson Parkman, Alice Bertaina, Kenneth I. Weinberg

Blood (2021) 138 (Supplement 1): 1794.

https://doi.org/10.1182/blood-2021-149690

Published: 2021

Journal Articles

Functional Immune Tolerance Induced By Sequential Hematopoietic Stem Cell-Solid Organ Transplantation

Alice Bertaina, Giulia Barbarito, Vasavi V. Ramachandran, Karen Kristovich, Elizabeth Amanda Lippner, Sahar Fathallah-Shaykh, Amira Al-Uzri, Ami J Shah, Geraldine Aubert, Priscila Ferreira Slepicka, Linda Oppizzi, Rajni Agarwal, Maria Grazia Roncarolo, Amy Gallo, Waldo Concepcion, Kenneth I. Weinberg, Robertson Parkman, David B Lewis, Paul C Grimm

Blood (2021) 138 (Supplement 1): 1818.

https://doi.org/10.1182/blood-2021-149920

Published: 2021

Journal Articles

Aberrant Histone Landscape in Juvenile Myelomonocytic Leukemia

Roshani Sinha, Mai Dvorak, Charlotte M. Niemeyer, Kathleen M. Sakamoto, Rachana Patil, Paul J Utz, Y. Lucy Liu, Alex Kuo, Alice Bertaina

Blood (2021) 138 (Supplement 1): 4328.

https://doi.org/10.1182/blood-2021-152074

Published: 2021

Journal Articles

Combinatorial Cytokine Secretion Signature of Donor-Derived T Cells Infused with the Graft: A New Potential Biomarker of Acute Graft-Versus-Host Disease in Αβt-Cell/CD19 B-Cell Depleted Hematopoietic Stem Cell Transplant Recipients

Raul Montiel-Esparza, Giulia Barbarito, Samantha Peck, Magali Bazzano, Rachana Patil, David C. Shyr, Gopin Saini, Robertson Parkman, Y. Lucy Liu, Alice Bertaina

Blood (2021) 138 (Supplement 1): 1684.

https://doi.org/10.1182/blood-2021-149948

Published: 2021

Journal Articles

MLN0128, a Potential Target Therapy for Myeloid Proliferation Neoplasia (MPN) with a Benefit of Prolonging Survival

Rachana Patil, Nitza Vara, Peter D. Emanuel, Alice Bertaina, Y. Lucy Liu

Blood (2021) 138 (Supplement 1): 1464.

https://doi.org/10.1182/blood-2021-151976

Published: 2021

Journal Articles

Heterogeneity of Hematopoietic Stem and Progenitor Cell (HSPC) Composition in Αβ T-Cell/CD19 B-Cell Depleted Peripheral Blood Cell Stem Cell (PBSC) Transplant Grafts and Correlation with Immune and Hematopoietic Recovery

Giulia Barbarito, Beruch Dejene, BS, David C Shyr, MD, Gopin Saini, MBBS, Linda Oppizzi, BS, Sruthi Mantri, Hye-Sook Kwon, PhD, Matthew H. Porteus, MD PhD, Kenneth I. Weinberg, MD, Alice Bertaina, MD PhD

Blood (2020) 136 (Supplement 1): 12–13.

https://doi.org/10.1182/blood-2020-143214

Published: 2020

Journal Articles

First Report of Non-Genotoxic Conditioning with JSP191 (anti-CD117) and Hematopoietic Stem Cell Transplantation in a Newly Diagnosed Patient with Severe Combined Immune Deficiency

Blood (2020) 136 (Supplement 1): 10.

https://doi.org/10.1182/blood-2020-137762

Published: 2020

Journal Articles

Comparison of Fixed Vs ALC-Based Doses of Thymoglobulin ® (ATG) in Pediatric Patients with Acute Leukemia Given αβhaplo-HSCT: Impact on Immune Reconstitution at Day 90

Giulia Barbarito, David C Shyr, MD, Gopin Saini, MBBS, Linda Oppizzi, BS, Y. Lucy Liu, MDPhD, Rachana Patil, MS, Jaap-Jan Boelens, MD PhD, Alice Bertaina, MD PhD

Blood (2020) 136 (Supplement 1): 16.

https://doi.org/10.1182/blood-2020-140461

Published: 2020

Journal Articles

Identification of Dual Positive CD19+/CD3+ T Cells in an Apheresis Product Undergoing Chimeric Antigen Receptor (CAR) Transduction

Liora M Schultz, MD, Shabnum Patel, PhD, Sneha Ramakrishna, MD, Alice Bertaina, MD PhD, Neehar Bhatia, Jean Oak, MD PhD, Robbie G. Majzner, MD, Christina Baggott, RN, PhD, Kara L. Davis, DO, Crystal L. Mackall, MD, Steven A Feldman, PhD

Blood (2019) 134 (Supplement_1): 4471.

https://doi.org/10.1182/blood-2019-129436

Published: 2019

Journal Articles

Results of a Multicentre, Randomized, Controlled Open-Label Study on the Use of Anti-T-Lymphocyte Globulin (ATLG) and Rituximab for Immunomodulation of Graft-Versus-Host Disease (GvHD) and Graft Failure (GF) in Patients with Non-Malignant Disorders

Mattia Algeri, MD, Stefania Galimberti, PhD, Maria Ester Bernardo, MD PhD, Attilio Rovelli, MD, Marco Zecca, MD, Giorgio La Nasa, MD, Sarah Marktel, MD, Pietro Merli, MD, Alice Bertaina, MD PhD, Daria Pagliara, MD PhD, Emilia Boccieri, MD, Francesca Del Bufalo, MD, Stefania Gaspari, MD, Giulia Capitoli, Maria Grazia Valsecchi, PhD, Franco Locatelli, MD PhD

Blood (2019) 134 (Supplement_1): 3280.

https://doi.org/10.1182/blood-2019-128925

Published: 2019

Journal Articles

High-Throughput RNA Sequencing Analysis Reveals Distinct Molecular Signature in NRAS and PTPN11 JMML Patients

Pier Paolo Leoncini, PhD, Alessandro Domenico Silvestris, PhD, Patrizia Vitullo, PhD, Marco Zecca, MD, Christian Flotho, MD PhD, Charlotte M. Niemeyer, MD, Angela Gallo, PhD, Alice Bertaina, MD PhD, Franco Locatelli, MD PhD, Pietro Merli, MD

Blood (2019) 134 (Supplement_1): 4229.

https://doi.org/10.1182/blood-2019-129965

Published: 2019

Journal Articles

Unrelated donor vs HLA-haploidentical α/β T-cell– and B-cell–depleted HSCT in children with acute leukemia

Blood (2018) 132 (24): 2594–2607.

https://doi.org/10.1182/blood-2018-07-861575

Published: 2018

Includes: Supplemental data

NARROW

T-allo10 Immunotherapy Results in Enhanced Early Immune Reconstitution and Reduced GvHD with Excellent Clinical Outcomes Post Αβ-Depleted HSCT in Pediatric and Young Adult Hematologic Malignancy Patients

Evaluation of Bone Marrow in Fanconi Anemia Patients Treated with Briquilimab Antibody-Based Conditioning and TCRαβ + T-Cell/CD19 + B-Cell Depleted Haploidentical Grafts

Towards Automated Engineering of Donor-Derived T Lymphocytes into CRISPR/Cas9-Mediated CAR T Cells in a Closed-System

Radiation and Busulfan-Free Hematopoietic Stem Cell Transplantation Using Briquilimab (JSP191) Anti-CD117 Antibody-Conditioning, Transient Immunosuppression and TCRαβ + T-Cell/CD19 + B-Cell Depleted Haploidentical Grafts in Patients with Fanconi Anemia

Targeting of CD25+ Activated T Cells in Gvhd-Associated Marrow Suppression and Cytopenias

Extracellular Release of Damaged Mitochondria Induced By Cytotoxic Conditioning Exacerbates Graft-Versus-Host Disease

Believe in haploidentical HSCT: less is better

Novel Humanized Loss-of-Function NF1 Mouse Model of Juvenile Myelomonocytic Leukemia

The Determinative Role of Hematopoietic Stem and Progenitor Cell Graft Composition on the Engraftment Kinetics after HSCT

Functional Immune Tolerance Induced By Sequential Hematopoietic Stem Cell-Solid Organ Transplantation

Aberrant Histone Landscape in Juvenile Myelomonocytic Leukemia

Combinatorial Cytokine Secretion Signature of Donor-Derived T Cells Infused with the Graft: A New Potential Biomarker of Acute Graft-Versus-Host Disease in Αβt-Cell/CD19 B-Cell Depleted Hematopoietic Stem Cell Transplant Recipients

MLN0128, a Potential Target Therapy for Myeloid Proliferation Neoplasia (MPN) with a Benefit of Prolonging Survival

Heterogeneity of Hematopoietic Stem and Progenitor Cell (HSPC) Composition in Αβ T-Cell/CD19 B-Cell Depleted Peripheral Blood Cell Stem Cell (PBSC) Transplant Grafts and Correlation with Immune and Hematopoietic Recovery

First Report of Non-Genotoxic Conditioning with JSP191 (anti-CD117) and Hematopoietic Stem Cell Transplantation in a Newly Diagnosed Patient with Severe Combined Immune Deficiency

Comparison of Fixed Vs ALC-Based Doses of Thymoglobulin ® (ATG) in Pediatric Patients with Acute Leukemia Given αβhaplo-HSCT: Impact on Immune Reconstitution at Day 90

Identification of Dual Positive CD19+/CD3+ T Cells in an Apheresis Product Undergoing Chimeric Antigen Receptor (CAR) Transduction

Results of a Multicentre, Randomized, Controlled Open-Label Study on the Use of Anti-T-Lymphocyte Globulin (ATLG) and Rituximab for Immunomodulation of Graft-Versus-Host Disease (GvHD) and Graft Failure (GF) in Patients with Non-Malignant Disorders

High-Throughput RNA Sequencing Analysis Reveals Distinct Molecular Signature in NRAS and PTPN11 JMML Patients

Unrelated donor vs HLA-haploidentical α/β T-cell– and B-cell–depleted HSCT in children with acute leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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