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Journal Articles

Radiation and Busulfan-Free Hematopoietic Stem Cell Transplantation Using Briquilimab (JSP191) Anti-CD117 Antibody-Conditioning, Transient Immunosuppression and TCRαβ + T-Cell/CD19 + B-Cell Depleted Haploidentical Grafts in Patients with Fanconi Anemia

Blood (2023) 142 (Supplement 1): 229.

https://doi.org/10.1182/blood-2023-178400

Published: 2023

Journal Articles

Lentiviral-mediated Gene Therapy for Patients with Fanconi Anemia [Group A]: Updated Results from Global RP-L102 Clinical Trials

Blood (2022) 140 (Supplement 1): 10646–10647.

https://doi.org/10.1182/blood-2022-168342

Published: 2022

Journal Articles

Non-Genotoxic Restoration of the Hematolymphoid System in Fanconi Anemia Mice through Antibody-Mediated Hematopoietic Stem Cell Transplantation

Yan Yi Chan, Pui Yan Ho, Leah Swartzrock, Maire Rayburn, Rofida Nofal, Supawat Thongthip, Kenneth I. Weinberg, Agnieszka Czechowicz

Blood (2022) 140 (Supplement 1): 7342–7344.

https://doi.org/10.1182/blood-2022-164809

Published: 2022

Journal Articles

Hematopoietic and Immunological Assessment in Fanconi Anemia after Ex Vivo Lentiviral FANCA Gene Therapy with RP-L102

Rofida Nofal, Yan Yi Chan, Sushmita Sen, Ulises Juarez Figueroa, Hana Willner, Matthias Felber, Mark Krampf, Supawat Thongthip, Grace Choi, Eileen Nicoletti, Jonathan D. Schwartz, Kenneth I. Weinberg, Alfredo Rodriguez, Rajni Agarwal, Maria Grazia Roncarolo, Agnieszka Czechowicz

Blood (2022) 140 (Supplement 1): 7772–7773.

https://doi.org/10.1182/blood-2022-157840

Published: 2022

Journal Articles

Gene Therapy for Fanconi Anemia [Group A]: Interim Results of RP-L102 Clinical Trials

Blood (2021) 138 (Supplement 1): 3968.

https://doi.org/10.1182/blood-2021-147071

Published: 2021

Journal Articles

Gene Therapy for Fanconi Anemia, Complementation Group a: Updated Results from Ongoing Global Clinical Studies of RP-L102

Agnieszka Czechowicz, MDPhD, Rajni Agarwal, MD, Julián Sevilla, MD PhD, Paula Río, PhD, Susana Navarro, PhD, Brian C Beard, PhD, Kenneth M Law, PhD, Grace Choi, BS, Miriam Zeini, PhD, Eileen Nicoletti, MD, John E Wagner, MD, Claire Booth, MBBS, PhD MSc, Jonathan D Schwartz, MD, Juan A Bueren, PhD, Maria Grazia Roncarolo, MD

Blood (2020) 136 (Supplement 1): 14.

https://doi.org/10.1182/blood-2020-137106

Published: 2020

Journal Articles

First Report of Non-Genotoxic Conditioning with JSP191 (anti-CD117) and Hematopoietic Stem Cell Transplantation in a Newly Diagnosed Patient with Severe Combined Immune Deficiency

Blood (2020) 136 (Supplement 1): 10.

https://doi.org/10.1182/blood-2020-137762

Published: 2020

Journal Articles

Changing the Natural History of Fanconi Anemia Complementation Group-A with Gene Therapy: Early Results of U.S. Phase I Study of Lentiviral-Mediated Ex-Vivo FANCA Gene Insertion in Human Stem and Progenitor Cells

Agnieszka Czechowicz, MD PhD, Maria Grazia Roncarolo, MD, Brian C Beard, PhD, Ken Law, PhD, Eileen Nicoletti, MD, Paula Río, PhD, Juan A. Bueren, PhD, Jonathan D Schwartz, MD, Sandeep Soni, MBBS

Blood (2019) 134 (Supplement_1): 3350.

https://doi.org/10.1182/blood-2019-127352

Published: 2019

Journal Articles

Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice

Hye-Sook Kwon, Aaron C. Logan, Akanksha Chhabra, Wendy W. Pang, Agnieszka Czechowicz, Keri Tate, Alan Le, Jessica Poyser, Roger Hollis, Benjamin V. Kelly, Donald B. Kohn, Irving L. Weissman, Susan S. Prohaska, Judith A. Shizuru

Blood (2019) 133 (19): 2104–2108.

https://doi.org/10.1182/blood-2018-06-853879

Published: 2019

Includes: Supplemental data

Journal Articles

Anti-CD117 antibody depletes normal and myelodysplastic syndrome human hematopoietic stem cells in xenografted mice

Wendy W. Pang, Agnieszka Czechowicz, Aaron C. Logan, Rashmi Bhardwaj, Jessica Poyser, Christopher Y. Park, Irving L. Weissman, Judith A. Shizuru

Blood (2019) 133 (19): 2069–2078.

https://doi.org/10.1182/blood-2018-06-858159

Published: 2019

Includes: Supplemental data

Journal Articles

Completely Non-Myeloablative/Non-Lymphoablative Conditioning for BMT/HSCT Using Anti-Ckit Immunotoxins

Agnieszka Czechowicz, MD PhD, Rahul Palchaudhuri, PhD, Amelia Scheck, BS, Jonathan Hoggatt, PhD, Borja Saez, PhD, David T. Scadden, MD, Derrick J. Rossi, PhD

Blood (2016) 128 (22): 493.

https://doi.org/10.1182/blood.V128.22.493.493

Published: 2016

Journal Articles

Enhanced Allogeneic Engraftment Achieved Via Prenatal Tolerance Induction and Postnatal Anti-CD45 Immunotoxin Conditioned Hematopoietic Cell Transplantation

Patrick E. McGovern, MD, Agnieszka Czechowicz, MD PhD, Ali Mejaddam, MD, John D. Stratigis, MD, Haiying Li, John Urwin, Lauren E. McClain, MD, Philip W. Zoltick, MD, Alan W. Flake, MD, William H. Peranteau, MD

Blood (2016) 128 (22): 2153.

https://doi.org/10.1182/blood.V128.22.2153.2153

Published: 2016

Journal Articles

In utero depletion of fetal hematopoietic stem cells improves engraftment after neonatal transplantation in mice

S. Christopher Derderian, P. Priya Togarrati, Charmin King, Patriss W. Moradi, Damien Reynaud, Agnieszka Czechowicz, Irving L. Weissman, Tippi C. MacKenzie

Blood (2014) 124 (6): 973–980.

https://doi.org/10.1182/blood-2014-02-550327

Published: 2014

Includes: Supplemental data

Journal Articles

In Utero Depletion Of Fetal Host Hematopoietic Stem Cells Improves Engraftment Following Neonatal Transplantation In Mice

Chris Derderian, MD, Charmin King, MS, Priya Togarrati, PhD, Agnieszka Czechowicz, MD, PhD, Ninnia Lescano, MS, Damien Reynaud, PhD, Emmanuelle Passegue, PhD, Irving L Weissman, MD, Tippi MacKenzie, MD

Blood (2013) 122 (21): 3240.

https://doi.org/10.1182/blood.V122.21.3240.3240

Published: 2013

Journal Articles

Anti-CD117 (c-Kit) Monoclonal Antibodies Deplete Human Hematopoietic Stem Cells and Facilitate Their Replacement in Humanized NOD/SCID/IL2Rγ −/− Mice: A Non-Toxic Conditioning Regimen for Allotransplantation

Aaron C. Logan, MD, PhD, Agnieszka Czechowicz, MD, PhD, Benjamin V. Kelley, BS, Theingi M. Thway, PhD, Ivan Magana, Mark R. Krampf, MS, Jessica Poyser, Roger P. Hollis, PhD, Donald B. Kohn, MD, Irving L. Weissman, MD, Judith A. Shizuru, MD, PhD

Blood (2012) 120 (21): 4099.

https://doi.org/10.1182/blood.V120.21.4099.4099

Published: 2012

Journal Articles

Clonal Level Lineage Commitment of Mouse Hematopoietic Stem Cells in Vivo

Rong Lu, PhD, Agnieszka Czechowicz, Jun Seita, Irving L. Weissman, MD

Blood (2012) 120 (21): 27.

https://doi.org/10.1182/blood.V120.21.27.27

Published: 2012

Journal Articles

Transplantation Conditioning Regimens Induce Different Hematopoietic Stem Cell Differentiation in Mice At the Clonal Level

Rong Lu, PhD, Agnieszka Czechowicz, PhD, Irving L. Weissman, MD

Blood (2011) 118 (21): 140.

https://doi.org/10.1182/blood.V118.21.140.140

Published: 2011

Journal Articles

Targeted Clearance of Human Hematopoietic Stem Cell Niches Via Inhibition of SCF Signaling Using Monoclonal Antibody SR-1

Agnieszka Czechowicz, PhD, Rashmi Bhardwaj, PhD, Christopher Y. Park, MD, PhD, Irving L. Weissman, MD

Blood (2010) 116 (21): 74.

https://doi.org/10.1182/blood.V116.21.74.74

Published: 2010

Journal Articles

Niche Recycling through Division-Independent Egress of Hematopoietic Stem Cells.

Agnieszka Czechowicz, Deepta Bhattacharya, PhD, Lisa Ooi, Derrick J Rossi, PhD, David Bryder, Irving L. Weissman

Blood (2009) 114 (22): 79.

https://doi.org/10.1182/blood.V114.22.79.79

Published: 2009

Journal Articles

Antibody-Based Depletion of Hematopoietic Stem Cells Empties Niches for Efficient Transplantation.

Agnieszka Czechowicz, Daniel L. Kraft, MD, Deepta Bhattacharya, PhD, Irving L. Weissman, MD

Blood (2007) 110 (11): LB2.

https://doi.org/10.1182/blood.V110.11.LB2.lb2

Published: 2007

NARROW

Radiation and Busulfan-Free Hematopoietic Stem Cell Transplantation Using Briquilimab (JSP191) Anti-CD117 Antibody-Conditioning, Transient Immunosuppression and TCRαβ + T-Cell/CD19 + B-Cell Depleted Haploidentical Grafts in Patients with Fanconi Anemia

Lentiviral-mediated Gene Therapy for Patients with Fanconi Anemia [Group A]: Updated Results from Global RP-L102 Clinical Trials

Non-Genotoxic Restoration of the Hematolymphoid System in Fanconi Anemia Mice through Antibody-Mediated Hematopoietic Stem Cell Transplantation

Hematopoietic and Immunological Assessment in Fanconi Anemia after Ex Vivo Lentiviral FANCA Gene Therapy with RP-L102

Gene Therapy for Fanconi Anemia [Group A]: Interim Results of RP-L102 Clinical Trials

Gene Therapy for Fanconi Anemia, Complementation Group a: Updated Results from Ongoing Global Clinical Studies of RP-L102

First Report of Non-Genotoxic Conditioning with JSP191 (anti-CD117) and Hematopoietic Stem Cell Transplantation in a Newly Diagnosed Patient with Severe Combined Immune Deficiency

Changing the Natural History of Fanconi Anemia Complementation Group-A with Gene Therapy: Early Results of U.S. Phase I Study of Lentiviral-Mediated Ex-Vivo FANCA Gene Insertion in Human Stem and Progenitor Cells

Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice

Anti-CD117 antibody depletes normal and myelodysplastic syndrome human hematopoietic stem cells in xenografted mice

Completely Non-Myeloablative/Non-Lymphoablative Conditioning for BMT/HSCT Using Anti-Ckit Immunotoxins

Enhanced Allogeneic Engraftment Achieved Via Prenatal Tolerance Induction and Postnatal Anti-CD45 Immunotoxin Conditioned Hematopoietic Cell Transplantation

In utero depletion of fetal hematopoietic stem cells improves engraftment after neonatal transplantation in mice

In Utero Depletion Of Fetal Host Hematopoietic Stem Cells Improves Engraftment Following Neonatal Transplantation In Mice

Anti-CD117 (c-Kit) Monoclonal Antibodies Deplete Human Hematopoietic Stem Cells and Facilitate Their Replacement in Humanized NOD/SCID/IL2Rγ −/− Mice: A Non-Toxic Conditioning Regimen for Allotransplantation

Clonal Level Lineage Commitment of Mouse Hematopoietic Stem Cells in Vivo

Transplantation Conditioning Regimens Induce Different Hematopoietic Stem Cell Differentiation in Mice At the Clonal Level

Targeted Clearance of Human Hematopoietic Stem Cell Niches Via Inhibition of SCF Signaling Using Monoclonal Antibody SR-1

Niche Recycling through Division-Independent Egress of Hematopoietic Stem Cells.

Antibody-Based Depletion of Hematopoietic Stem Cells Empties Niches for Efficient Transplantation.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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