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Journal Articles

Evaluation of Bone Marrow in Fanconi Anemia Patients Treated with Briquilimab Antibody-Based Conditioning and TCRαβ + T-Cell/CD19 + B-Cell Depleted Haploidentical Grafts

Charmaine Fay Soco, Mark R. Krampf, Yan Yi Chan, Hana Hoang, Nivedita Kunte, Gopin Saini, Kenneth I. Weinberg, Robertson Parkman, Alice Bertaina, Rajni Agarwal, Matthew Porteus, Agnieszka D. Czechowicz

Blood (2024) 144 (Supplement 1): 2015.

https://doi.org/10.1182/blood-2024-206381

Published: 2024

Journal Articles

Heterogeneity of Human Invariant Natural Killer T Cells, Including Novel Naïve-like CD8 + and Temra-like CD4 - CD8 - Populations, Revealed through Single Cell RNA-Sequencing

Melissa Mavers, Derek Hollingsworth, Reyka G. Jayasinghe, Chaiyaporn Boonchalermvichian, Biki Gupta, Hao Yan, Jeanette Baker, Beruh Dejene, Kenneth I. Weinberg, Robert S. Negrin

Blood (2023) 142 (Supplement 1): 152.

https://doi.org/10.1182/blood-2023-182442

Published: 2023

Journal Articles

Radiation and Busulfan-Free Hematopoietic Stem Cell Transplantation Using Briquilimab (JSP191) Anti-CD117 Antibody-Conditioning, Transient Immunosuppression and TCRαβ + T-Cell/CD19 + B-Cell Depleted Haploidentical Grafts in Patients with Fanconi Anemia

Blood (2023) 142 (Supplement 1): 229.

https://doi.org/10.1182/blood-2023-178400

Published: 2023

Journal Articles

Targeting of CD25+ Activated T Cells in Gvhd-Associated Marrow Suppression and Cytopenias

Tami D. John, Laura Valine, Giulia Barbarito, Hye-Sook Kwon, Sally Arai, Beth Martin-Kool, Radhika Kumari, Judith Shizuru, Jean S. Oak, Robertson Parkman, Alice Bertaina, Kenneth I. Weinberg

Blood (2023) 142 (Supplement 1): 7033.

https://doi.org/10.1182/blood-2023-190968

Published: 2023

Journal Articles

Extracellular Release of Damaged Mitochondria Induced By Cytotoxic Conditioning Exacerbates Graft-Versus-Host Disease

Vijith Vijayan, Hao Yan, Juliane Lohmeyer, Kaylin Prentiss, Rachana Patil, Giulia Barbarito, Ivan Lopez, Aly Elezaby, Kolten Peterson, Jeanette Baker, Nicolai Ostberg, Alice Bertaina, Robert S. Negrin, Daria Mochly-Rosen, Kenneth I. Weinberg, Bereketeab Haileselassie

Blood (2023) 142 (Supplement 1): 2051.

https://doi.org/10.1182/blood-2023-179456

Published: 2023

Journal Articles

Non-Genotoxic Restoration of the Hematolymphoid System in Fanconi Anemia Mice through Antibody-Mediated Hematopoietic Stem Cell Transplantation

Yan Yi Chan, Pui Yan Ho, Leah Swartzrock, Maire Rayburn, Rofida Nofal, Supawat Thongthip, Kenneth I. Weinberg, Agnieszka Czechowicz

Blood (2022) 140 (Supplement 1): 7342–7344.

https://doi.org/10.1182/blood-2022-164809

Published: 2022

Journal Articles

Hematopoietic and Immunological Assessment in Fanconi Anemia after Ex Vivo Lentiviral FANCA Gene Therapy with RP-L102

Rofida Nofal, Yan Yi Chan, Sushmita Sen, Ulises Juarez Figueroa, Hana Willner, Matthias Felber, Mark Krampf, Supawat Thongthip, Grace Choi, Eileen Nicoletti, Jonathan D. Schwartz, Kenneth I. Weinberg, Alfredo Rodriguez, Rajni Agarwal, Maria Grazia Roncarolo, Agnieszka Czechowicz

Blood (2022) 140 (Supplement 1): 7772–7773.

https://doi.org/10.1182/blood-2022-157840

Published: 2022

Journal Articles

The Determinative Role of Hematopoietic Stem and Progenitor Cell Graft Composition on the Engraftment Kinetics after HSCT

Giulia Barbarito, Beruh Dejene, Gopin Saini, Rachana Patil, David C. Shyr, Robertson Parkman, Alice Bertaina, Kenneth I. Weinberg

Blood (2021) 138 (Supplement 1): 1794.

https://doi.org/10.1182/blood-2021-149690

Published: 2021

Journal Articles

Functional Immune Tolerance Induced By Sequential Hematopoietic Stem Cell-Solid Organ Transplantation

Alice Bertaina, Giulia Barbarito, Vasavi V. Ramachandran, Karen Kristovich, Elizabeth Amanda Lippner, Sahar Fathallah-Shaykh, Amira Al-Uzri, Ami J Shah, Geraldine Aubert, Priscila Ferreira Slepicka, Linda Oppizzi, Rajni Agarwal, Maria Grazia Roncarolo, Amy Gallo, Waldo Concepcion, Kenneth I. Weinberg, Robertson Parkman, David B Lewis, Paul C Grimm

Blood (2021) 138 (Supplement 1): 1818.

https://doi.org/10.1182/blood-2021-149920

Published: 2021

Journal Articles

AML Cell Vaccines Co-Expressing CD80 and IL-15/IL-15 Receptor Alpha Induce Activation and Cytolytic Activity in Post Remission Autologous Patient PBMC Ex Vivo

Xinyue Wang, Jeffrey P. Fung, Giulia Parisi, Francesca M. Olguin, Nathaniel Z. Rothschild, Kenneth I. Weinberg, William J. Murphy, Donald B. Kohn, Karin L. Gaensler

Blood (2021) 138 (Supplement 1): 1706.

https://doi.org/10.1182/blood-2021-151614

Published: 2021

Journal Articles

Heterogeneity of Hematopoietic Stem and Progenitor Cell (HSPC) Composition in Αβ T-Cell/CD19 B-Cell Depleted Peripheral Blood Cell Stem Cell (PBSC) Transplant Grafts and Correlation with Immune and Hematopoietic Recovery

Giulia Barbarito, Beruch Dejene, BS, David C Shyr, MD, Gopin Saini, MBBS, Linda Oppizzi, BS, Sruthi Mantri, Hye-Sook Kwon, PhD, Matthew H. Porteus, MD PhD, Kenneth I. Weinberg, MD, Alice Bertaina, MD PhD

Blood (2020) 136 (Supplement 1): 12–13.

https://doi.org/10.1182/blood-2020-143214

Published: 2020

Journal Articles

First Report of Non-Genotoxic Conditioning with JSP191 (anti-CD117) and Hematopoietic Stem Cell Transplantation in a Newly Diagnosed Patient with Severe Combined Immune Deficiency

Blood (2020) 136 (Supplement 1): 10.

https://doi.org/10.1182/blood-2020-137762

Published: 2020

Journal Articles

Pharmacologic Activation of Aldehyde Metabolism to Protect Hematopoietic Stem Cells (HSC) in Murine Models of Fanconi Anemia (FA)

Jennifer Tsai, MD, Kelsey R. Logas, MS, Lauren D. Van Wassenhove, PhD, Beruh Dejene, BS, Che-Hong Chen, PhD, Daria Mochly-Rosen, PhD, Kenneth I. Weinberg, MD

Blood (2019) 134 (Supplement_1): 105.

https://doi.org/10.1182/blood-2019-124439

Published: 2019

Journal Articles

Non-Genotoxic Anti-CD117 Antibody Conditioning Results in Successful Hematopoietic Stem Cell Engraftment in Patients with Severe Combined Immunodeficiency

Rajni Agarwal, MD, Christopher C. Dvorak, MD, Hye-Sook Kwon, PhD, Janel R Long-Boyle, PharmD, PhD, Susan S Prohaska, PhD MS, Janice W Brown, MD, Anne Le, Alyssa Guttman-Klein, Irving L Weissman, MD, Morton J Cowan, MD, Aaron C. Logan, MD PhD, Kenneth I. Weinberg, MD, Robertson Parkman, MD, Maria-Grazia Roncarolo, MD, Judith A Shizuru, MD PhD

Blood (2019) 134 (Supplement_1): 800.

https://doi.org/10.1182/blood-2019-126239

Published: 2019

Journal Articles

High Resolution Mapping of Human Lymphopoiesis Reveals a Common Lymphoid Progenitor (CLP) Population

Nivedita Shankar Saxena, BA, Kara L. Davis, DO, Matthew Arthur Inlay, PhD BA, Astraea Junger, Yujun Yang, Mark L. Krampf, MS, Beruh Dejene, Garry P. Nolan, Prof, PhD, Irving L Weissman, MD, Kenneth I. Weinberg, MD

Blood (2016) 128 (22): 1473.

https://doi.org/10.1182/blood.V128.22.1473.1473

Published: 2016

Journal Articles

Anti-Fungal Prophylaxis Using Intermediate Dose Ambisome Is Associated with Delayed Methotrexate Clearance in Pediatric Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Liora M. Schultz, MD, Karan Kumar, MD, Suzette Stone, Elizabeth Callard, Jessica Witkowski, MD, Leigh Shinn, Lisa Pinner, Shizuka Franklin, Julianna Kula, Namrata Patel, Prianka Kumar, Kenneth I. Weinberg, MD, Matthew Porteus, MD PhD, Rajni Agarwal, MD, Ami Shah, MD, Sandhya Kharbanda, MD

Blood (2016) 128 (22): 5762.

https://doi.org/10.1182/blood.V128.22.5762.5762

Published: 2016

Journal Articles

Dissection of Complementary Vs Unique Cntributions of Kit, Flt3 and IL-7R Signaling to Lymphohematopoietic Development in Vivo

Nivedita Shankar Saxena, BA, Jing Huang, Yujun Yang, MD, Dullei Min, PhD, Carmencita Nicolas, Sumana Shashidhar, BSc, MSc, MA, Janice (Wes) Brown, MD, Kenneth I Weinberg, MD

Blood (2014) 124 (21): 1572.

https://doi.org/10.1182/blood.V124.21.1572.1572

Published: 2014

Journal Articles

Alloreactive T Cell Clonotypes Identified By In Vitro Mixed Lymphoid Reaction and High-Throughput Sequencing Exhibit Increased Frequency In Peripheral Blood Samples From Patients Following Allogeneic Hematopoietic Cell Transplantation For Chronic Lymphocytic Leukemia

Aaron C. Logan, MD, PhD, Mark R. Krampf, MS, Mark Klinger, PhD, Martin Moorhead, PhD, Jianbiao Zheng, PhD, Randall Armstrong, Malek Faham, MD, PhD, Kenneth I Weinberg, MD, David B. Miklos, MD, PhD

Blood (2013) 122 (21): 149.

https://doi.org/10.1182/blood.V122.21.149.149

Published: 2013

Journal Articles

RB Controls Size, Cellularity, and T Cell Output of the Mouse Thymus

Phillip M. Garfin, MD, PhD, Patrick Viatour, PharmD, PhD, Dullei Min, PhD, Jerrod Bryson, PhD, Kenneth I. Weinberg, MD, Nancy R. Manley, PhD, Julien Sage, PhD

Blood (2012) 120 (21): 835.

https://doi.org/10.1182/blood.V120.21.835.835

Published: 2012

Journal Articles

Gene therapy for adenosine deaminase–deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans

Blood (2012) 120 (18): 3635–3646.

https://doi.org/10.1182/blood-2012-02-400937

Published: 2012

Includes: Supplemental data

NARROW

Evaluation of Bone Marrow in Fanconi Anemia Patients Treated with Briquilimab Antibody-Based Conditioning and TCRαβ + T-Cell/CD19 + B-Cell Depleted Haploidentical Grafts

Heterogeneity of Human Invariant Natural Killer T Cells, Including Novel Naïve-like CD8 + and Temra-like CD4 - CD8 - Populations, Revealed through Single Cell RNA-Sequencing

Radiation and Busulfan-Free Hematopoietic Stem Cell Transplantation Using Briquilimab (JSP191) Anti-CD117 Antibody-Conditioning, Transient Immunosuppression and TCRαβ + T-Cell/CD19 + B-Cell Depleted Haploidentical Grafts in Patients with Fanconi Anemia

Targeting of CD25+ Activated T Cells in Gvhd-Associated Marrow Suppression and Cytopenias

Extracellular Release of Damaged Mitochondria Induced By Cytotoxic Conditioning Exacerbates Graft-Versus-Host Disease

Non-Genotoxic Restoration of the Hematolymphoid System in Fanconi Anemia Mice through Antibody-Mediated Hematopoietic Stem Cell Transplantation

Hematopoietic and Immunological Assessment in Fanconi Anemia after Ex Vivo Lentiviral FANCA Gene Therapy with RP-L102

The Determinative Role of Hematopoietic Stem and Progenitor Cell Graft Composition on the Engraftment Kinetics after HSCT

Functional Immune Tolerance Induced By Sequential Hematopoietic Stem Cell-Solid Organ Transplantation

AML Cell Vaccines Co-Expressing CD80 and IL-15/IL-15 Receptor Alpha Induce Activation and Cytolytic Activity in Post Remission Autologous Patient PBMC Ex Vivo

Heterogeneity of Hematopoietic Stem and Progenitor Cell (HSPC) Composition in Αβ T-Cell/CD19 B-Cell Depleted Peripheral Blood Cell Stem Cell (PBSC) Transplant Grafts and Correlation with Immune and Hematopoietic Recovery

First Report of Non-Genotoxic Conditioning with JSP191 (anti-CD117) and Hematopoietic Stem Cell Transplantation in a Newly Diagnosed Patient with Severe Combined Immune Deficiency

Pharmacologic Activation of Aldehyde Metabolism to Protect Hematopoietic Stem Cells (HSC) in Murine Models of Fanconi Anemia (FA)

Non-Genotoxic Anti-CD117 Antibody Conditioning Results in Successful Hematopoietic Stem Cell Engraftment in Patients with Severe Combined Immunodeficiency

High Resolution Mapping of Human Lymphopoiesis Reveals a Common Lymphoid Progenitor (CLP) Population

Anti-Fungal Prophylaxis Using Intermediate Dose Ambisome Is Associated with Delayed Methotrexate Clearance in Pediatric Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation

Dissection of Complementary Vs Unique Cntributions of Kit, Flt3 and IL-7R Signaling to Lymphohematopoietic Development in Vivo

Alloreactive T Cell Clonotypes Identified By In Vitro Mixed Lymphoid Reaction and High-Throughput Sequencing Exhibit Increased Frequency In Peripheral Blood Samples From Patients Following Allogeneic Hematopoietic Cell Transplantation For Chronic Lymphocytic Leukemia

RB Controls Size, Cellularity, and T Cell Output of the Mouse Thymus

Gene therapy for adenosine deaminase–deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans

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American Society of Hematology

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American Society of Hematology

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