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Journal Articles

Adding CD117 Antibody to Alemtuzumab, Low Dose Total Body Irradiation (TBI), and Sirolimus for Matched Related Donor (MRD) Hematopoietic Cell Transplant (HCT) in Sickle Cell Disease (SCD): Initial Results

Matthew Hsieh, Priscilla Pollack, Elizabeth Harvey, Triscia Martin, Neal Jeffries, Wendy W Pang, John Tisdale

Blood (2024) 144 (Supplement 1): 1141.

https://doi.org/10.1182/blood-2024-200214

Published: 2024

Journal Articles

Radiation and Busulfan-Free Hematopoietic Stem Cell Transplantation Using Briquilimab (JSP191) Anti-CD117 Antibody-Conditioning, Transient Immunosuppression and TCRαβ + T-Cell/CD19 + B-Cell Depleted Haploidentical Grafts in Patients with Fanconi Anemia

Blood (2023) 142 (Supplement 1): 229.

https://doi.org/10.1182/blood-2023-178400

Published: 2023

Journal Articles

Final Results from Phase 1 Study of Briquilimab, an Anti-CD117 Monoclonal Antibody, in Combination with Low Dose Irradiation and Fludarabine Conditioning, Shows Durable Remissions in Older Adults with Acute Myeloid Leukemia in Complete Remission and Myelodysplastic Syndrome Undergoing Allogeneic Hematopoietic Cell Transplantation

Arpita Gandhi, Andrew Artz, Catherine J. Lee, Ankur Varma, Bart L. Scott, Hye-Sook Kwon, Minyoung Youn, Chikako Yanagiba, Jeyakavitha Arulprakasam, Anne Le, Judith Shizuru, Wendy W Pang, Lori S. Muffly

Blood (2023) 142 (Supplement 1): 470.

https://doi.org/10.1182/blood-2023-185533

Published: 2023

Journal Articles

JSP191 As a Single-Agent Conditioning Regimen Results in Successful Engraftment, Donor Myeloid Chimerism, and Production of Donor Derived Naïve Lymphocytes in Patients with Severe Combined Immunodeficiency (SCID)

Blood (2021) 138 (Supplement 1): 554.

https://doi.org/10.1182/blood-2021-153074

Published: 2021

Journal Articles

5-Azacytidine Depletes Hematopoietic Stem Cells and Synergizes with an Anti-CD117 Antibody to Augment Engraftment of Donor Stem Cells in Immunocompetent Mice

Andriyana K Bankova, MD, Wendy W Pang, MD PhD, Brenda J Velasco, Janel R Long-Boyle, PharmD, PhD, Judith A Shizuru, MD PhD

Blood (2020) 136 (Supplement 1): 23–24.

https://doi.org/10.1182/blood-2020-139058

Published: 2020

Journal Articles

Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice

Hye-Sook Kwon, Aaron C. Logan, Akanksha Chhabra, Wendy W. Pang, Agnieszka Czechowicz, Keri Tate, Alan Le, Jessica Poyser, Roger Hollis, Benjamin V. Kelly, Donald B. Kohn, Irving L. Weissman, Susan S. Prohaska, Judith A. Shizuru

Blood (2019) 133 (19): 2104–2108.

https://doi.org/10.1182/blood-2018-06-853879

Published: 2019

Includes: Supplemental data

Journal Articles

Anti-CD117 antibody depletes normal and myelodysplastic syndrome human hematopoietic stem cells in xenografted mice

Wendy W. Pang, Agnieszka Czechowicz, Aaron C. Logan, Rashmi Bhardwaj, Jessica Poyser, Christopher Y. Park, Irving L. Weissman, Judith A. Shizuru

Blood (2019) 133 (19): 2069–2078.

https://doi.org/10.1182/blood-2018-06-858159

Published: 2019

Includes: Supplemental data

Journal Articles

BLT-humanized C57BL/6 Rag2 −/− γ c −/− CD47 −/− mice are resistant to GVHD and develop B- and T-cell immunity to HIV infection

Kerry J. Lavender, Wendy W. Pang, Ronald J. Messer, Amanda K. Duley, Brent Race, Katie Phillips, Dana Scott, Karin E. Peterson, Charles K. Chan, Ulf Dittmer, Timothy Dudek, Todd M. Allen, Irving L. Weissman, Kim J. Hasenkrug

Blood (2013) 122 (25): 4013–4020.

https://doi.org/10.1182/blood-2013-06-506949

Published: 2013

Includes: Supplemental data

Journal Articles

Unexplained Anemia In The Elderly Is Due To An Intrinsic Defect In Hematopoietic Stem Cells

Wendy W. Pang, M.D., Ph.D., John V. Pluvinage, Yasuo Mori, M.D., Ph.D., Elizabeth Price, MD, MPH, Amittha Wickrema, PhD, Oyebimpe Adensina, M.D., Andrew Artz, MD, Irving L. Weissman, MD, Stanley L. Schrier, MD

Blood (2013) 122 (21): 2187.

https://doi.org/10.1182/blood.V122.21.2187.2187

Published: 2013

Journal Articles

CD99 Identifies Disease Stem Cells in Acute Myeloid Leukemia and the Myelodysplastic Syndromes

Stephen S. Chung, MD, Wendy W Pang, Ph.D., Gino K. In, MD, Max Jan, PhD, Virginia M. Klimek, M.D., Ari Melnick, MD, Irving L. Weissman, MD, Ravi Majeti, MD, PhD, Christopher Y. Park, MD, PhD

Blood (2012) 120 (21): 210.

https://doi.org/10.1182/blood.V120.21.210.210

Published: 2012

Journal Articles

Hematopoietic Stem Cells Are the Disease-Initiating Cells in the Myelodysplastic Syndromes

Christopher Y. Park, MD, PhD, Wendy W Pang, Ph.D., Elizabeth Price, MD, MPH, John A. Pluvinage, Stanley L. Schrier, MD, Irving L. Weissman

Blood (2011) 118 (21): 789.

https://doi.org/10.1182/blood.V118.21.789.789

Published: 2011

Journal Articles

Reduced ribosomal protein gene dosage and p53 activation in low-risk myelodysplastic syndrome

Kelly A. McGowan, Wendy W. Pang, Rashmi Bhardwaj, Marcelina G. Perez, John V. Pluvinage, Bertil E. Glader, Reem Malek, Susan M. Mendrysa, Irving L. Weissman, Christopher Y. Park, Gregory S. Barsh

Blood (2011) 118 (13): 3622–3633.

https://doi.org/10.1182/blood-2010-11-318584

Published: 2011

Includes: Supplemental data

Journal Articles

Myelodysplastic Syndromes Are Characterized by Gene Expression Changes in Hematopoietic Stem Cells and Alterations in Hematopoietic Stem Cell and Myeloid Progenitor Composition.

Christopher Y. Park, MD, PhD, Wendy W Pang, Peter L Greenberg, MD, Irving L. Weissman, MD

Blood (2009) 114 (22): 1762.

https://doi.org/10.1182/blood.V114.22.1762.1762

Published: 2009

Journal Articles

Hematopoiesis in the Elderly: Age-Associated Effects in Frequency, Function, and Gene Expression of Human Hematopoietic Stem Cells.

Wendy W. Pang, Elizabeth A. Price, MD, MPH, Irving L. Weissman, MD, Stanley L. Schrier, MD

Blood (2009) 114 (22): 1505.

https://doi.org/10.1182/blood.V114.22.1505.1505

Published: 2009

Journal Articles

NPM1 Haploinsufficiency Results in Increased Numbers of Hematopoietic Stem Cells and Progenitor Cells.

Aparna Raval, Christopher Y. Park, Wendy W Pang, Brenda Kusler, Kunju Joshi Sridhar, Jason R Gotlib, Peter L Greenberg, Irving L. Weissman, Beverly S. Mitchell

Blood (2009) 114 (22): 738.

https://doi.org/10.1182/blood.V114.22.738.738

Published: 2009

Journal Articles

CD47 Is An Independent Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

Ravindra Majeti, MD, PhD, Mark P. Chao, Ash A. Alizadeh, MD, PhD, Wendy W. Pang, Irving L. Weissman, MD

Blood (2008) 112 (11): 766.

https://doi.org/10.1182/blood.V112.11.766.766

Published: 2008

Journal Articles

Genetic Susceptibility Loci for Lethal Graft-Versus-Host Disease in MHC-Identical Mice: Initial Results from a Genome-Wide Scan.

Thai M. Cao, MD, Wendy W. Pang, F. Carl Grumet, MD, Laura C. Lazzeroni, PhD, Judith A. Shizuru, PhD, MD

Blood (2004) 104 (11): 4986.

https://doi.org/10.1182/blood.V104.11.4986.4986

Published: 2004

NARROW

Adding CD117 Antibody to Alemtuzumab, Low Dose Total Body Irradiation (TBI), and Sirolimus for Matched Related Donor (MRD) Hematopoietic Cell Transplant (HCT) in Sickle Cell Disease (SCD): Initial Results

Radiation and Busulfan-Free Hematopoietic Stem Cell Transplantation Using Briquilimab (JSP191) Anti-CD117 Antibody-Conditioning, Transient Immunosuppression and TCRαβ + T-Cell/CD19 + B-Cell Depleted Haploidentical Grafts in Patients with Fanconi Anemia

JSP191 As a Single-Agent Conditioning Regimen Results in Successful Engraftment, Donor Myeloid Chimerism, and Production of Donor Derived Naïve Lymphocytes in Patients with Severe Combined Immunodeficiency (SCID)

5-Azacytidine Depletes Hematopoietic Stem Cells and Synergizes with an Anti-CD117 Antibody to Augment Engraftment of Donor Stem Cells in Immunocompetent Mice

Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice

Anti-CD117 antibody depletes normal and myelodysplastic syndrome human hematopoietic stem cells in xenografted mice

BLT-humanized C57BL/6 Rag2 −/− γ c −/− CD47 −/− mice are resistant to GVHD and develop B- and T-cell immunity to HIV infection

Unexplained Anemia In The Elderly Is Due To An Intrinsic Defect In Hematopoietic Stem Cells

CD99 Identifies Disease Stem Cells in Acute Myeloid Leukemia and the Myelodysplastic Syndromes

Hematopoietic Stem Cells Are the Disease-Initiating Cells in the Myelodysplastic Syndromes

Reduced ribosomal protein gene dosage and p53 activation in low-risk myelodysplastic syndrome

Myelodysplastic Syndromes Are Characterized by Gene Expression Changes in Hematopoietic Stem Cells and Alterations in Hematopoietic Stem Cell and Myeloid Progenitor Composition.

Hematopoiesis in the Elderly: Age-Associated Effects in Frequency, Function, and Gene Expression of Human Hematopoietic Stem Cells.

NPM1 Haploinsufficiency Results in Increased Numbers of Hematopoietic Stem Cells and Progenitor Cells.

CD47 Is An Independent Prognostic Factor and Therapeutic Antibody Target on Human Acute Myeloid Leukemia Stem Cells

Genetic Susceptibility Loci for Lethal Graft-Versus-Host Disease in MHC-Identical Mice: Initial Results from a Genome-Wide Scan.

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American Society of Hematology

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American Society of Hematology

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