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Journal Articles

Reduced chronic graft versus host disease after allogeneic HSCT with cryopreserved peripheral blood stem cell grafts: A CIBMTR analysis

Alexandria Maurer, Tao Wang, Zachariah Defilipp, Jakob Devos, Nosha Farhadfar, Pooja Khandelwal, Stephen Spellman, Najla El Jurdi, Stephanie Lee, Robert Soiffer

Blood (2025) 146 (Supplement 1): 933.

https://doi.org/10.1182/blood-2025-933

Published: 2025

Journal Articles

Post-transplant cyclophosphamide based GVHD prophylaxis in HLA-matched related and unrelated donor hematopoietic cell transplantation in adults with hematologic malignancies undergoing myeloablative conditioning: A CIBMTR analysis of 8,272 participants

Pashna Munshi, Tao Wang, Shannon McCurdy, Rajneesh Nath, Cuyler Huffman, Nosha Farhadfar, Zachariah Defilipp, Pooja Khandelwal, Wael Saber, Stephen Spellman, Najla El Jurdi, Stephanie Lee, Zheng Zhou

Blood (2025) 146 (Supplement 1): 931.

https://doi.org/10.1182/blood-2025-931

Published: 2025

Journal Articles

Response dynamics to belumosudil in chronic graft-versus-host disease: Characterizing late responses and organ-specific response expectations from the rockstar study

Zachariah Defilipp, Lauren Rota, Kathy Marshall, Yu Yao, Ran Ji, Alaa Ali

Blood (2025) 146 (Supplement 1): 6004.

https://doi.org/10.1182/blood-2025-6004

Published: 2025

Journal Articles

Can we perform allogeneic hematopoietic cell transplantation (HCT) safely in patients with limited social supports and substantial psychosocial complexity?

Nicolas Trad, Matthew Reynolds, Maya Abdallah, John Mark Sloan, Richard Newcomb, Jennifer D'Alotto, Julie Vanderklish, Nived Subhendu, Michelle Lee, Zachariah Defilipp, Thomas Spitzer, Yi-Bin Chen, Areej El-Jawahri

Blood (2025) 146 (Supplement 1): 4617.

https://doi.org/10.1182/blood-2025-4617

Published: 2025

Journal Articles

Trial in progress: A phase 3, randomized, double-blind, placebo-controlled study of axatilimab and corticosteroids as initial treatment for moderate to severe chronic graft-versus-host disease

Zachariah Defilipp, Maureen Bleam, Chuan Tian, Albert Assad

Blood (2025) 146 (Supplement 1): 4256.

https://doi.org/10.1182/blood-2025-4256

Published: 2025

Journal Articles

Safety and feasibility of 0.6 mg/kg every 4 weeks dosing of axatilimab in patients treated in the AGAVE-201 study

Nosha Farhadfar, Maria Sola Soto, Saurabh Chhabra, Valkal Bhatt, Emily Andersen, Zhenyi Xue, Zachariah Defilipp

Blood (2025) 146 (Supplement 1): 272.

https://doi.org/10.1182/blood-2025-272

Published: 2025

Journal Articles

RGI-2001 for the prophylaxis of acute graft-versus-host disease after allogeneic HCT

Zachariah DeFilipp, Hannah Choe, Yvonne A. Efebera, Ayman Saad, Shatha Farhan, Lazaros Lekakis, Jean A. Yared, Gary Schiller, Markus Y. Mapara, Amer Assal, Ted Gooley, Jack D. Bui, Dana Lee, Hayley Lane, Yi-Bin Chen

Blood (2025) 146 (17): 2037–2046.

https://doi.org/10.1182/blood.2025029584

Published: 2025

Includes: Supplemental data

Journal Articles

Low rates of chronic graft-versus-host disease with ruxolitinib maintenance following allogeneic HCT

Zachariah DeFilipp, Haesook T. Kim, Laura W. Knight, Suzanne M. O’Connor, Shilton E. Dhaver, Meghan White, Bhagirathbhai Dholaria, Mark A. Schroeder, Sumithira Vasu, Sameem Abedin, Jooho Chung, Areej El-Jawahri, Matthew J. Frigault, Steven McAfee, Richard A. Newcomb, Paul V. O’Donnell, Thomas R. Spitzer, Yi-Bin Chen, Gabriela S. Hobbs

Blood (2025) 145 (20): 2312–2316.

https://doi.org/10.1182/blood.2024028005

Published: 2025

Includes: Supplemental data

Journal Articles

Can JAK inhibition prevent GVHD?

Zachariah DeFilipp

Blood (2024) 144 (22): 2273–2274.

https://doi.org/10.1182/blood.2024026193

Published: 2024

Journal Articles

Serial Clinical and Biomarker Monitoring during Treatment Can Stratify Patients with Low Risk Gvhd

Blood (2024) 144 (Supplement 1): 380.

https://doi.org/10.1182/blood-2024-204010

Published: 2024

Journal Articles

Vitamin A keeps the GVHD away?

Zachariah DeFilipp

Blood (2024) 143 (12): 1067.

https://doi.org/10.1182/blood.2024023828

Published: 2024

Journal Articles

Spatial transcriptomics reveals distinct tissue niches linked with steroid responsiveness in acute gastrointestinal GVHD

Bidish K. Patel, Michael J. Raabe, Evan R. Lang, Yuhui Song, Chenyue Lu, Vikram Deshpande, Linda T. Nieman, Martin J. Aryee, Yi-Bin Chen, David T. Ting, Zachariah DeFilipp

Blood (2023) 142 (21): 1831–1844.

https://doi.org/10.1182/blood.2023020644

Published: 2023

Includes: Supplemental data

Journal Articles

Multimodal Mobile Application to Address Sexual Dysfunction in Hematopoietic Stem Cell Transplant (HCT) Survivors

Areej El-Jawahri, Jennifer Reese, Lara Traeger, Don Dizon, Sharon Bober, Julie Vanderklish, Richard Newcomb, Zachariah Defilipp, Yi-Bin Chen, Jennifer Temel

Blood (2023) 142 (Supplement 1): 5142.

https://doi.org/10.1182/blood-2023-185776

Published: 2023

Journal Articles

Maintenance Ruxolitinib Is Associated with Low Rates of Chronic Gvhd Requiring Systemic Treatment in Older Adults with AML/MDS Undergoing Allogeneic HCT: Results of a Phase II Multicenter Trial

Zachariah Defilipp, Haesook T. Kim, Laura Knight, Suzanne O'Connor, Meghan White, Bhagirathbhai Dholaria, Mark A. Schroeder, Sumithira Vasu, Sameem Abedin, Areej El-Jawahri, Steven McAfee, Yi-Bin Chen, Gabriela S. Hobbs

Blood (2023) 142 (Supplement 1): 653.

https://doi.org/10.1182/blood-2023-180423

Published: 2023

Journal Articles

A Day 14 Endpoint for Acute Gvhd Clinical Trials

Blood (2023) 142 (Supplement 1): 779.

https://doi.org/10.1182/blood-2023-172955

Published: 2023

Journal Articles

Impact of Investigational Microbiome Therapeutic SER-155 on Pathogen Domination: Initial Results from a Phase 1b Study in Adults Undergoing Allogeneic Hematopoietic Cell Transplantation (HCT)

Jonathan U. Peled, Marcel R.M. van den Brink, Doris M. Ponce, Satyajit Kosuri, Nandita Khera, Zachariah DeFilipp, Bina Tejura, David I Lichter, Mary-Jane Lombardo, Meghan Chafee, Jennifer R Wortman, Timothy Straub, Emily Walsh, Augustus Ge, David Lyttle, Brooke Hasson, Christopher Ford, Lisa von Moltke, Matthew Henn

Blood (2023) 142 (Supplement 1): 2198.

https://doi.org/10.1182/blood-2023-188885

Published: 2023

Journal Articles

Updated Findings of a Phase II Study of Ruxolitinib Pre-, during- and Post-Hematopoietic Stem Cell Transplantation for Patients with Primary or Secondary Myelofibrosis

Gabriela S. Hobbs, Haesook T. Kim, Suzanne O'Connor, Mark A. Schroeder, Roni Tamari, Sarah A Wall, Areej El-Jawahri, Steven McAfee, Jessica Hem, Patricia Lozano, Jonas S. Jutzi, Ann Mullally, Yi-Bin Chen, Zachariah Defilipp

Blood (2023) 142 (Supplement 1): 2103.

https://doi.org/10.1182/blood-2023-178645

Published: 2023

Journal Articles

Multi-Site Randomized Trial of Inpatient Palliative Care for Hospitalized Patients Undergoing Hematopoietic Stem Cell Transplantation

Areej El-Jawahri, Thomas W LeBlanc, Alison Kavanaugh, Jason Webb, James Fausto, Lara Traeger, Joseph Greer, Vicki Jackson, Nora Horick, Zachariah Defilipp, Yi-Bin Chen, Stephanie J. Lee, Jennifer Temel

Blood (2023) 142 (Supplement 1): 913.

https://doi.org/10.1182/blood-2023-185735

Published: 2023

Journal Articles

Effective Prevention of Steroid-Requiring Chronic Graft-Vs.-Host Disease with B Cell Depletion: A Randomized, Placebo-Controlled Trial

Blood (2023) 142 (Supplement 1): 649.

https://doi.org/10.1182/blood-2023-180142

Published: 2023

Journal Articles

Preliminary Safety Results of the Open-Label Phase of a 2-Part Phase 1b Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of an Investigational Microbiome Therapeutic, SER-155, in Adults Undergoing Hematopoietic Cell Transplantation

Doris M. Ponce, Satyajit Kosuri, Nandita Khera, Zachariah Defilipp, David I Lichter, Jonathan U Peled, Marcel R.M. van den Brink, Kelly Brady, Matthew D Puhl, Gabrielle Glick, Brooke Hasson, Barbara H McGovern, Lisa von Moltke, Bina Tejura

Blood (2023) 142 (Supplement 1): 6994.

https://doi.org/10.1182/blood-2023-180119

Published: 2023

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Reduced chronic graft versus host disease after allogeneic HSCT with cryopreserved peripheral blood stem cell grafts: A CIBMTR analysis

Post-transplant cyclophosphamide based GVHD prophylaxis in HLA-matched related and unrelated donor hematopoietic cell transplantation in adults with hematologic malignancies undergoing myeloablative conditioning: A CIBMTR analysis of 8,272 participants

Response dynamics to belumosudil in chronic graft-versus-host disease: Characterizing late responses and organ-specific response expectations from the rockstar study

Can we perform allogeneic hematopoietic cell transplantation (HCT) safely in patients with limited social supports and substantial psychosocial complexity?

Trial in progress: A phase 3, randomized, double-blind, placebo-controlled study of axatilimab and corticosteroids as initial treatment for moderate to severe chronic graft-versus-host disease

Safety and feasibility of 0.6 mg/kg every 4 weeks dosing of axatilimab in patients treated in the AGAVE-201 study

RGI-2001 for the prophylaxis of acute graft-versus-host disease after allogeneic HCT

Low rates of chronic graft-versus-host disease with ruxolitinib maintenance following allogeneic HCT

Can JAK inhibition prevent GVHD?

Serial Clinical and Biomarker Monitoring during Treatment Can Stratify Patients with Low Risk Gvhd

Vitamin A keeps the GVHD away?

Spatial transcriptomics reveals distinct tissue niches linked with steroid responsiveness in acute gastrointestinal GVHD

Multimodal Mobile Application to Address Sexual Dysfunction in Hematopoietic Stem Cell Transplant (HCT) Survivors

Maintenance Ruxolitinib Is Associated with Low Rates of Chronic Gvhd Requiring Systemic Treatment in Older Adults with AML/MDS Undergoing Allogeneic HCT: Results of a Phase II Multicenter Trial

A Day 14 Endpoint for Acute Gvhd Clinical Trials

Impact of Investigational Microbiome Therapeutic SER-155 on Pathogen Domination: Initial Results from a Phase 1b Study in Adults Undergoing Allogeneic Hematopoietic Cell Transplantation (HCT)

Updated Findings of a Phase II Study of Ruxolitinib Pre-, during- and Post-Hematopoietic Stem Cell Transplantation for Patients with Primary or Secondary Myelofibrosis

Multi-Site Randomized Trial of Inpatient Palliative Care for Hospitalized Patients Undergoing Hematopoietic Stem Cell Transplantation

Effective Prevention of Steroid-Requiring Chronic Graft-Vs.-Host Disease with B Cell Depletion: A Randomized, Placebo-Controlled Trial

Preliminary Safety Results of the Open-Label Phase of a 2-Part Phase 1b Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of an Investigational Microbiome Therapeutic, SER-155, in Adults Undergoing Hematopoietic Cell Transplantation

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American Society of Hematology

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