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Michelle Lee
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Journal Articles

Bruton Tyrosine Kinase Inhibitor Rilzabrutinib Reduces Vaso-Occlusion and Markers of Inflammation and Adhesion in Transgenic Mice with Sickle Cell Disease

Ahmed Daak, David R. Light, Fuad Abdulla, Chunsheng Chen, Julia Nguyen, Conglin Ruan, Michael Storek, Dimitry Ofengeim, Alexandra Hicks, Michelle Lee, Vincent Mikol, Gregory M. Vercellotti, John D. Belcher
Journal: Blood
Blood (2024) 144 (Supplement 1): 2482.
https://doi.org/10.1182/blood-2024-200182
Published: 2024
Journal Articles

Gamma Secretase Inhibition May Mitigate the Impact of Low BCMA Target Density in Relapsed/Refractory Multiple Myeloma: Results from a Comparative Analysis of Two Phase 1 Clinical Trials

Andrew J Portuguese, Sherilyn A. Tuazon, Margot J. Pont, Gabriel Cole, Blythe Duke Sather, Xiaoling Song, Brent L. Wood, Michelle Lee Blake, Melissa Works, Mazyar Shadman, Qian Vicky Wu, Jenna M. Voutsinas, Ted Gooley, Cameron J. Turtle, Brian G. Till, David G. Coffey, David G. Maloney, Edward Libby, Aude G Chapuis, Filippo Milano, Stanley R. Riddell, Andrew J. Cowan, Damian J. Green
Journal: Blood
Blood (2024) 144 (Supplement 1): 4832.
https://doi.org/10.1182/blood-2024-205942
Published: 2024
Journal Articles

Sustained Complement C1s Inhibition with Sutimlimab in Patients with Cold Agglutinin Disease Results in Continued Efficacy during Part B of the Randomized Placebo-Controlled Phase 3 Cadenza Study (NCT03347422)

Alexander Roeth, Sigbjørn Berentsen, Wilma Barcellini, Shirley D'Sa, Bernd Jilma, Marc Michel, Ilene C. Weitz, Masaki Yamaguchi, Jun-ichi Nishimura, Josephine M.I. Vos, Joan Cid, Michael Storek, Nancy Wong, Ronnie Yoo, Jennifer Wang, Deepthi Vagge, Marek Wardecki, Frank Shafer, Michelle Lee, Catherine M. Broome
Journal: Blood
Blood (2022) 140 (Supplement 1): 2825–2827.
https://doi.org/10.1182/blood-2022-159562
Published: 2022
Journal Articles

Sutimlimab Provides Sustained Improvements in Patient-Reported Outcomes and Quality of Life in Patients with Cold Agglutinin Disease: Open-Label Extension of the Randomized, Phase 3 Cadenza Study

Alexander Roeth, Catherine M. Broome, Wilma Barcellini, Bernd Jilma, Quentin A. Hill, David Cella, Tor Henrik Anderson Tvedt, Masaki Yamaguchi, Irina Murakhovskaya, Michelle Lee, Frank Shafer, Marek Wardecki, Jennifer Wang, Ronnie Yoo, Jerome Mshijid, Ilene C. Weitz
Journal: Blood
Blood (2022) 140 (Supplement 1): 70–72.
https://doi.org/10.1182/blood-2022-159966
Published: 2022
Journal Articles

Sutimlimab in patients with cold agglutinin disease: results of the randomized placebo-controlled phase 3 CADENZA trial

Clinical Trials & Observations
Alexander Röth, Sigbjørn Berentsen, Wilma Barcellini, Shirley D’Sa, Bernd Jilma, Marc Michel, Ilene C. Weitz, Masaki Yamaguchi, Jun-ichi Nishimura, Josephine M. I. Vos, Michael Storek, Nancy Wong, Parija Patel, Xiaoyu Jiang, Deepthi S. Vagge, Marek Wardęcki, Frank Shafer, Michelle Lee, Catherine M. Broome
Journal: Blood
Blood (2022) 140 (9): 980–991.
https://doi.org/10.1182/blood.2021014955
Published: 2022
Includes: Supplemental data
Journal Articles

Inhibition of Complement C1s By Sutimlimab in Patients with Cold Agglutinin Disease (CAD): Efficacy and Safety Results from the Randomized, Placebo-Controlled Phase 3 CADENZA Study

Alexander Roeth, Sigbjørn Berentsen, Wilma Barcellini, Shirley D'Sa, Bernd Jilma, Marc Michel, Ilene C. Weitz, Masaki Yamaguchi, Jun-Ichi Nishimura, Josephine M.I. Vos, Michael Storek, Nancy Wong, Parija Patel, Braydon Schaible, Xiaoyu Jiang, Deepthi Vagge, Marek Wardecki, Frank Shafer, Michelle Lee, Catherine M. Broome
Journal: Blood
Blood (2021) 138 (Supplement 1): 349.
https://doi.org/10.1182/blood-2021-148066
Published: 2021
Journal Articles

Inhibition of Complement C1s with Sutimlimab in Patients with Cold Agglutinin Disease (CAD): Interim Results of the Phase 3 Cardinal Study Long-Term Follow-up

Alexander Röth, MD, Wilma Barcellini, Shirley D'Sa, Yoshitaka Miyakawa, Catherine M Broome, Marc Michel, David J. Kuter, MD, Bernd Jilma, Tor Henrik Anderson Tvedt, Ilene C. Weitz, Parija Patel, Xiaoyu Jiang, Caroline Reuter, Jun Su, Frank Shafer, Michelle Lee, William Hobbs, Sigbjørn Berentsen
Journal: Blood
Blood (2020) 136 (Supplement 1): 24–25.
https://doi.org/10.1182/blood-2020-138909
Published: 2020
Journal Articles

A murine model of severe immune thrombocytopenia is induced by antibody- and CD8 + T cell–mediated responses that are differentially sensitive to therapy

Leola Chow, Rukhsana Aslam, Edwin R. Speck, Michael Kim, Norman Cridland, Michelle Lee Webster, Pingguo Chen, Kim Sahib, Heyu Ni, Alan H. Lazarus, M. Bernadette Garvey, John Freedman, John W. Semple
Journal: Blood
Blood (2010) 115 (6): 1247–1253.
https://doi.org/10.1182/blood-2009-09-244772
Published: 2010
Includes: Supplemental data
Journal Articles

Antibody- and Cell-Mediated Immune Thrombocytopenia Are Differentially Sensitive to Intravenous Gammaglobulin Therapy

Leola Chow, PhD, Michael Kim, BSc, Edwin R. Speck, BRT, Rukhsana Aslam, PhD, Michelle Lee Webster, MSc, Pingguo Chen, PhD, Heyu Ni, MD, PhD, John Freedman, MD, John W. Semple, PhD
Journal: Blood
Blood (2008) 112 (11): 399.
https://doi.org/10.1182/blood.V112.11.399.399
Published: 2008
Journal Articles

Novel Mouse Anti-Mouse β3 Integrin Monoclonal Antibodies: Development and Characterization of New Reagents for Research in Thrombosis and Thrombocytopenia.

Guangheng Zhu, MD, Michelle Lee Webster, MSc, Adili Reheman, MD, Pingguo Chen, MD, PhD, Ebrahim Sayeh, PhD, Hong Yang, MD, Ming Wang, MSc, John Freedman, MD, Heyu Ni, MD, PhD
Journal: Blood
Blood (2007) 110 (11): 2107.
https://doi.org/10.1182/blood.V110.11.2107.2107
Published: 2007
Journal Articles

Relative efficacy of intravenous immunoglobulin G in ameliorating thrombocytopenia induced by antiplatelet GPIIbIIIa versus GPIbα antibodies

Brief Report
Michelle Lee Webster, Ebrahim Sayeh, Min Crow, Pingguo Chen, Bernhard Nieswandt, John Freedman, Heyu Ni
Journal: Blood
Blood (2006) 108 (3): 943–946.
https://doi.org/10.1182/blood-2005-06-009761
Published: 2006