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Luis E. Aguirre
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Journal Articles

Myelodysplastic Syndromes with Concomitant SF3B1 Mutation and Deletion of the Long Arm of Chromosome 5 ( SF3B1 del5q ): Outcomes and Response to Treatment

Rami S. Komrokji, Zaker I. Schwabkey, Najla H. Al Ali, Luis E. Aguirre, Maximilian Stahl, Somedeb Ball, Emily F. Mason, Michael R. Savona, Valeria Santini, Angela Consagra, Uwe Platzbecker, Anne Sophie Kubasch, Yazan F Madanat, Pierre Fenaux, Lin-Pierre Zhao, Mikkael A. Sekeres, Namrata S. Chandhok, Matteo Giovanni Della Porta, Luca Lanino, Amy E. DeZern, David Sallman, Zhuoer Xie, Eric Padron, Koji Sasaki, Kensuke Takaoka, Akhil Jain, Mónica Del Rey, Maria Diez-Campelo, Guillermo Garcia-Manero
Journal: Blood
Blood (2024) 144 (Supplement 1): 1845.
https://doi.org/10.1182/blood-2024-207474
Published: 2024
Journal Articles

Impact of Molecular Ontogeny on Hematological Recovery in AML Patients Treated with Hypomethylating Agent Plus Venetoclax Therapy

Josh Zhang, Shai O. Shimony, Yiwen Liu, Eno Inyang, Evan C. Chen, Luis E. Aguirre, Rebecca P. Bystrom, Benjamin Rolles, Richard M. Stone, Daniel J. DeAngelo, Emily Tiao, Maximilian Stahl
Journal: Blood
Blood (2024) 144 (Supplement 1): 5175.
https://doi.org/10.1182/blood-2024-200358
Published: 2024
Journal Articles

Outcomes with HMA Plus Venetoclax Vs Intensive Chemotherapy in AML Patients with Chromosome 5 and 7 Abnormalities

Leora Boussi, Jan Philipp Bewersdorf, Yiwen Liu, Rory M. Shallis, Luis E. Aguirre, Andrius Zucenka, Sylvain Garciaz, Rebecca P. Bystrom, Daniel J. DeAngelo, Richard M Stone, Marlise R. Luskin, Jacqueline S. Garcia, Eric S. Winer, Evan Chen, Martha Wadleigh, Kelly Ling, Amer M. Zeidan, Aaron D. Goldberg, Eytan M. Stein, Shai O. Shimony, Maximilian Stahl
Journal: Blood
Blood (2024) 144 (Supplement 1): 4281.
https://doi.org/10.1182/blood-2024-204467
Published: 2024
Journal Articles

The Prognostic and Predictive Value of RUNX1 Mutations in Newly Diagnosed Acute Myeloid Leukemia - an International Multicenter Cohort Study

Rebecca P. Bystrom, Jan Philipp Bewersdorf, Yiwen Liu, Eva Johanna Schaefer, Rory M. Shallis, Leora Boussi, Andrius Zucenka, Sylvain Garciaz, Luis E. Aguirre, Daniel J. DeAngelo, Richard M. Stone, Marlise R. Luskin, Jacqueline S. Garcia, Eric S. Winer, Evan C. Chen, Martha Wadleigh, Kelly Ling, Eytan M. Stein, Aaron D. Goldberg, Amer M. Zeidan, Shai O. Shimony, Maximilian Stahl
Journal: Blood
Blood (2024) 144 (Supplement 1): 2947.
https://doi.org/10.1182/blood-2024-205581
Published: 2024
Journal Articles

Comparative Analysis of Outcomes with HMA Plus Venetoclax Vs Intensive Chemotherapy in AML Patients Harboring Very-High Risk Cytogenetics

Luis E. Aguirre, Jan Philipp Bewersdorf, Yiwen Liu, Rory M. Shallis, Leora Boussi, Andrius Zucenka, Sylvain Garciaz, Rebecca P. Bystrom, Daniel J. DeAngelo, Richard M. Stone, Marlise R. Luskin, Jacqueline S. Garcia, Eric S. Winer, Kelly Ling, Evan C. Chen, Martha Wadleigh, Eytan M. Stein, Aaron D. Goldberg, Amer M. Zeidan, Shai O. Shimony, Maximilian Stahl
Journal: Blood
Blood (2024) 144 (Supplement 1): 4267.
https://doi.org/10.1182/blood-2024-202744
Published: 2024
Journal Articles

Venetoclax-Based Therapy Versus Intensive Chemotherapy Followed By Allogeneic-Stem Cell Transplantation for High-Risk Elderly Acute Myeloid Leukemia

Alexandre Iat, Jan Philipp Bewersdorf, Julia Gilhodes, Yiwen Liu, Rory M. Shallis, Leora Boussi, Andrius Zucenka, Rebecca P. Bystrom, Daniel J. DeAngelo, Guillaume Berton, Amel Soua, Kelly Ling, Luis E. Aguirre, Richard M Stone, Marlise R. Luskin, Jacqueline S. Garcia, Eric S. Winer, Evan C. Chen, Martha Wadleigh, Aaron D. Goldberg, Amer M. Zeidan, Thomas Cluzeau, Shai O. Shimony, Maximilian Stahl, Sylvain Garciaz
Journal: Blood
Blood (2024) 144 (Supplement 1): 1508.
https://doi.org/10.1182/blood-2024-207045
Published: 2024
Journal Articles

Redefining Clinical Response Criteria in Myelodysplastic Syndromes to Better Forecast Post-Transplant Outcomes

Luis E. Aguirre, Haesook T. Kim, Hany Elmariah, Stacey M. Frumm, Amar H. Kelkar, Vincent T. Ho, Mahasweta Gooptu, John Koreth, Roman M. Shapiro, Rizwan Romee, Sarah Nikiforow, Joseph H. Antin, Robert J. Soiffer, Benjamin Rolles, Shai O. Shimony, Marlise R. Luskin, Jacqueline S. Garcia, Kelly Ling, Evan C. Chen, Martha Wadleigh, Eric S. Winer, Richard M. Stone, Daniel J. DeAngelo, Najla H. Al Ali, Corey S. Cutler, Rami S. Komrokji, Maximilian Stahl
Journal: Blood
Blood (2024) 144 (Supplement 1): 4938.
https://doi.org/10.1182/blood-2024-209087
Published: 2024
Journal Articles

Improved Overall Survival Among Luspatercept Responders and Predictors of Response

Angela Consagra, Luca Lanino, Najla H Al Ali, Luis E. Aguirre, Zhuoer Xie, Onyee Chan, Gloria Andreossi, Luca Rigodanza, Alessandro Sanna, Marco Gabriele Raddi, Alison R. Walker, Andrew T. Kuykendall, Jeffrey Lancet, Eric Padron, David A Sallman, Francesco Restuccia, Alessandra Perego, Marta Ubezio, Bruno Fattizzo, Marta Riva, Alessia Campagna, Matteo Giovanni Della Porta, Valeria Santini, Rami S. Komrokji
Journal: Blood
Blood (2023) 142 (Supplement 1): 1871.
https://doi.org/10.1182/blood-2023-186279
Published: 2023
Journal Articles

Data-Driven Harmonization of 2022 Who and ICC Classifications of Myelodysplastic Syndromes/Neoplasms (MDS): A Study By the International Consortium for MDS (icMDS)

Luca Lanino, Somedeb Ball, Jan Philipp Bewersdorf, Monia Marchetti, Giulia Maggioni, Erica Travaglino, Najla H Al Ali, Pierre Fenaux, Uwe Platzbecker, Valeria Santini, Maria Diez-Campelo, Avani M Singh, Akriti Gupta Jain, Luis E. Aguirre, Sara M. Tinsley-Vance, Zaker I. Schwabkey, Onyee Chan, Zhuoer Xie, Andrew M. Brunner, Andrew T. Kuykendall, John M. Bennett, Rena Buckstein, Rafael Bejar, Hetty E. Carraway, Amy E. DeZern, Elizabeth A. Griffiths, Stephanie Halene, Robert Hasserjian, Jeffrey Lancet, Alan F. List, Sanam Loghavi, Olatoyosi Odenike, Eric Padron, Mrinal M. Patnaik, Gail J. Roboz, Maximilian Stahl, Mikkael A. Sekeres, David Peter Steensma, Michael R. Savona, Justin Taylor, Mina Xu, Kendra Sweet, David A Sallman, Stephen D. Nimer, Christopher S. Hourigan, Andrew H. Wei, Elisabetta Sauta, Saverio D'Amico, Gianluca Asti, Gastone Castellani, Uma M. Borate, Guillermo Sanz, Fabio Efficace, Steven D. Gore, Tae Kon Kim, Naval Daver, Guillermo Garcia-Manero, María Rozman, Alberto Orfao, Sa A. Wang, M. Kathy Foucar, Ulrich Germing, Torsten Haferlach, Phillip Scheinberg, Yasushi Miyazaki, Marcelo Iastrebner, Austin Kulasekararaj, Thomas Cluzeau, Shahram Kordasti, Arjan A. van de Loosdrecht, Lionel Ades, Amer M. Zeidan, Rami S. Komrokji, Matteo Giovanni Della Porta
Journal: Blood
Blood (2023) 142 (Supplement 1): 998.
https://doi.org/10.1182/blood-2023-186580
Published: 2023
Journal Articles

Outcomes in Patients with Acute Myeloid Leukemia Treated with CLAG (cladribine, cytarabine, filgrastim) and/or Mitoxantrone with Venetoclax

Onyee Chan, Luis E. Aguirre, Mary Burke, Najla H Al Ali, Zhuoer Xie, Seongseok Yun, Andrew T. Kuykendall, Eric Padron, Alison R. Walker, Jeffrey Lancet, Rami S. Komrokji, David A Sallman
Journal: Blood
Blood (2023) 142 (Supplement 1): 5935.
https://doi.org/10.1182/blood-2023-173637
Published: 2023
Journal Articles

Drivers of Deep Molecular Response and Outcomes in Patients with Core Binding Factor Acute Myeloid Leukemia

Somedeb Ball, Akriti G Jain, Parth C. Patel, Chen Wang, Luis E. Aguirre, Mohammad O Hussaini, Onyee Chan, Seongseok Yun, Andrew Kuykendall, Eric Padron, Kendra Sweet, Jeffrey E. Lancet, Rami S. Komrokji, David A. Sallman
Journal: Blood
Blood (2022) 140 (Supplement 1): 6282–6284.
https://doi.org/10.1182/blood-2022-170442
Published: 2022
Journal Articles

Subclonal KIT D816V Mutations Are Prevalent in Chronic Myelomonocytic Leukemia and Correlate with Distinct Phenotypic Features

Anthony Hunter, Hannah Newman, Eric Solary, Klaus Geissler, Laura Palomo, Lurdes Zamora, Francesc Solé, Valeria Santini, Timothy A. Graubert, Swapna Thota, Elizabeth A. Griffiths, Lisa Pleyer, Felicitas R. Thol, Rafael Bejar, Luis E. Aguirre, David A. Sallman, Andrew Kuykendall, Rami S. Komrokji, Tracy I. George, Eric Padron
Journal: Blood
Blood (2022) 140 (Supplement 1): 9824–9827.
https://doi.org/10.1182/blood-2022-164816
Published: 2022
Journal Articles

Assessment of the Molecular International Prognostic Scoring System (IPSS-M) Risk Stratification Model in Therapy-Related Myelodysplastic Syndromes

Luis E. Aguirre, Najla Al Ali, Somedeb Ball, Avani M Singh, Akriti G Jain, Onyee Chan, Zaker I. Schwabkey, Sara M Tinsley-Vance, Andrew Kuykendall, Kendra Sweet, Jeffrey E. Lancet, Eric Padron, David A. Sallman, Rami S. Komrokji
Journal: Blood
Blood (2022) 140 (Supplement 1): 9813–9815.
https://doi.org/10.1182/blood-2022-170980
Published: 2022
Journal Articles

A Product of "Clash of Titans" or True Reflection of Disease Biology? Validation of 2022 WHO and ICC Classifications in a Large Dataset of Patients with Myelodysplastic Syndrome

Somedeb Ball, Avani M Singh, Najla Al Ali, Luis E. Aguirre, Akriti G Jain, Zaker I. Schwabkey, Sara M Tinsley-Vance, Onyee Chan, Andrew Kuykendall, Kendra Sweet, Jeffrey E. Lancet, Eric Padron, David A. Sallman, Rami S. Komrokji
Journal: Blood
Blood (2022) 140 (Supplement 1): 1118–1120.
https://doi.org/10.1182/blood-2022-170158
Published: 2022
Journal Articles

Hypoplastic MDS: Validation of the New World Health Organization 2022 Proposal

Zaker I. Schwabkey, Amin Azem, Najla Al Ali, Somedeb Ball, Luis E. Aguirre, Akriti G Jain, Avani M Singh, Sara M Tinsley-Vance, Onyee Chan, Jeffrey E. Lancet, Kendra Sweet, Andrew Kuykendall, Eric Padron, David A. Sallman, Rami S. Komrokji
Journal: Blood
Blood (2022) 140 (Supplement 1): 6974–6975.
https://doi.org/10.1182/blood-2022-156974
Published: 2022
Journal Articles

Validation of the Molecular International Prognostic Scoring System (IPSS-M) Risk Stratification Model for Myelodysplastic Syndromes

Luis E. Aguirre, Najla Al Ali, Somedeb Ball, Avani M Singh, Akriti G Jain, Onyee Chan, Zaker I. Schwabkey, Sara M Tinsley-Vance, Andrew Kuykendall, Kendra Sweet, Jeffrey E. Lancet, Eric Padron, David A. Sallman, Rami S. Komrokji
Journal: Blood
Blood (2022) 140 (Supplement 1): 1125–1127.
https://doi.org/10.1182/blood-2022-170878
Published: 2022
Journal Articles

Synergistic Activity of Luspatercept and Erythroid Stimulating Agents Combination for Treatment of Anemia in Lower-Risk Myelodysplastic Syndromes

Rami S. Komrokji, Luis E. Aguirre, Najla Al Ali, Onyee Chan, Andrew Kuykendall, Kendra Sweet, Jeffrey E. Lancet, Eric Padron, David A. Sallman
Journal: Blood
Blood (2022) 140 (Supplement 1): 6917–6919.
https://doi.org/10.1182/blood-2022-169560
Published: 2022
Journal Articles

Assessment of the Molecular International Prognostic Scoring System (IPSS-M) Risk Stratification Model in Hypoplastic Myelodysplastic Syndromes

Luis E. Aguirre, Najla Al Ali, Somedeb Ball, Avani M Singh, Akriti G Jain, Onyee Chan, Zaker I. Schwabkey, Sara M Tinsley-Vance, Andrew Kuykendall, Kendra Sweet, Jeffrey E. Lancet, Eric Padron, David A. Sallman, Rami S. Komrokji
Journal: Blood
Blood (2022) 140 (Supplement 1): 6909–6911.
https://doi.org/10.1182/blood-2022-171044
Published: 2022
Journal Articles

Characterization of TP53 -Mutated Myelodysplastic Syndromes and Impact of Allelic Status and Concurrent Cytogenetic Abnormalities on Survival Outcomes

Luis E. Aguirre, Najla Al Ali, Akriti G Jain, Onyee Chan, Somedeb Ball, Andrew Kuykendall, Kendra Sweet, Jeffrey E. Lancet, Eric Padron, Rami S. Komrokji, David A. Sallman
Journal: Blood
Blood (2022) 140 (Supplement 1): 4034–4035.
https://doi.org/10.1182/blood-2022-171093
Published: 2022
Journal Articles

Clinico-Molecular Features and Treatment Outcomes in Primary Myelofibrosis Phenotypes with Protracted Disease Dynamics

Luis E. Aguirre, Akriti G Jain, Somedeb Ball, Najla Al Ali, Sara Marie Tinsley-Vance, David A. Sallman, Kendra Sweet, Jeffrey E. Lancet, Eric Padron, Andrew T. Kuykendall, Rami S. Komrokji
Journal: Blood
Blood (2021) 138 (Supplement 1): 2571.
https://doi.org/10.1182/blood-2021-152026
Published: 2021