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Daniel J DeAngelo
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Journal Articles

Tyrosine Kinase Inhibitor (TKI) Response in Patients with Chronic Myelogenous Leukemia (CML) and BCR-ABL 35 Base Pair Intron 8 Insertion (35INS)

Roxana A Portillo, Michelle Hyunju Lee, Harrison K. Tsai, Daniel J DeAngelo, Amir T. Fathi, Rupa Narayan, Marlise R Luskin, Gabriela S. Hobbs
Journal: Blood
Blood (2024) 144 (Supplement 1): 6598.
https://doi.org/10.1182/blood-2024-206655
Published: 2024
Journal Articles

Apex Part 2 Trial in Progress: A Phase 2 Open-Label Clinical Study of Bezuclastinib in Adult Patients with Advanced Systemic Mastocytosis

Isaac Goncalves, Stephen Fuller, Jason Gotlib, Pankit Vachhani, Vinod Pullarkat, Daniel J. DeAngelo, Saskia K. Klein, Wolfgang R. Sperr, Karin Hartmann, Khalid Shoumariyeh, Jens Panse, Teng Fong Ng, Miguel Piris-Villaespesa, Tsewang Tashi, Anthony M. Hunter, Prithviraj Bose, Cecilia Y. Arana Yi, Manish Jain, Helena Pomares, Tracy I. George, Jay Patel, Cristina Papayannidis, Minakshi S. Taparia, Bulai Livideanu Cridtina, Juliana Schwaab, Ingunn Dybedal, Jonathan Lambert, Tania Jain, Ewa Wierzbicka-Hainaut, Olivier Hermine, Massimiliano Bonifacio, Gabriela S. Hobbs, Michael W. Deininger, Amanda Pilla, Marcus Carden, Deepti H. Radia
Journal: Blood
Blood (2024) 144 (Supplement 1): 4569.1.
https://doi.org/10.1182/blood-2024-194550
Published: 2024
Journal Articles

A Phase 1 Study of Avapritinib in Combination with Decitabine in Patients with Systemic Mastocytosis with an Associated Hematologic Neoplasm

Andrew T. Kuykendall, Somedeb Ball, Jason Gotlib, Cecilia Y. Arana Yi, Tsewang Tashi, Raajit Rampal, Daniel J DeAngelo, Virginia O. Volpe, Kristen M. Pettit, Gerard Hoehn, Sasa Dimitrijevic, Rami S. Komrokji, Eric Padron
Journal: Blood
Blood (2024) 144 (Supplement 1): 4569.2.
https://doi.org/10.1182/blood-2024-211148
Published: 2024
Journal Articles

Obecabtagene autoleucel (obe-cel) for Adult Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia (R/R B-ALL) in the Open-Label, Multi-Center, Global, Single-Arm, Phase Ib/II FELIX Study: The Impact of Bridging Therapies on CAR T-Cell Expansion and Persistence

Jae H. Park, Elias Jabbour, Paul Shaughnessy, Aaron C. Logan, Karamjeet S Sandhu, Mehrdad Abedi, Bijal D Shah, Michael R Bishop, Daniel J. DeAngelo, Pierre Lao-Sirieix, Wolfram Brugger, Martin A Pule, Justin Shang, Claire Roddie
Journal: Blood
Blood (2024) 144 (Supplement 1): 3458.
https://doi.org/10.1182/blood-2024-201514
Published: 2024
Journal Articles

Impact of Molecular Ontogeny on Hematological Recovery in AML Patients Treated with Hypomethylating Agent Plus Venetoclax Therapy

Josh Zhang, Shai O. Shimony, Yiwen Liu, Eno Inyang, Evan C. Chen, Luis E. Aguirre, Rebecca P. Bystrom, Benjamin Rolles, Richard M. Stone, Daniel J. DeAngelo, Emily Tiao, Maximilian Stahl
Journal: Blood
Blood (2024) 144 (Supplement 1): 5175.
https://doi.org/10.1182/blood-2024-200358
Published: 2024
Journal Articles

Impact of Social Determinants of Health on Overall Survival in Patients with AML By European Leukemianet Risk Group

Shai O. Shimony, Yating Wang, Angel Cronin, Thomas P Walsh, Anne Charles, Natalie Slopen, Maximilian Stahl, Rebecca P. Bystrom, Marlise R. Luskin, Gregory Abel, Daniel J. DeAngelo, Richard M Stone, R. Coleman Lindsley, Andrew Hantel
Journal: Blood
Blood (2024) 144 (Supplement 1): 5171.
https://doi.org/10.1182/blood-2024-203644
Published: 2024
Journal Articles

Apex Part 1: Updated Assessment of Bezuclastinib (CGT9486), a Selective KIT D816V Tyrosine Kinase Inhibitor, in Patients with Advanced Systemic Mastocytosis (AdvSM)

Daniel J. DeAngelo, Jason Gotlib, Vinod Pullarkat, Pankit Vachhani, Tsewang Tashi, Stephanie Lee, Gary J. Schiller, Anthony M. Hunter, Miguel Piris-Villaespesa, Helena Pomares, Bulai Livideanu Cridtina, Khalid Shoumariyeh, Jonathan Lambert, Tracy I. George, Jay Patel, Cristina Papayannidis, Tania Jain, Michael W. Deininger, Andreas Reiter, Gabriela S. Hobbs, Lei Sun, Deepak Nagendra, Jenna Zhang, Amanda Pilla, Kim Dishman, Marcus Carden, Deepti H. Radia
Journal: Blood
Blood (2024) 144 (Supplement 1): 659.
https://doi.org/10.1182/blood-2024-193678
Published: 2024
Journal Articles

Efficacy and Safety of Uproleselan Combined with Chemotherapy Vs. Chemotherapy Alone in Relapsed/Refractory Acute Myeloid Leukemia: Findings from an International Phase 3 Trial

Daniel J. DeAngelo, Andre C. Schuh, Brian A. Jonas, Pamela S. Becker, Anjali S. Advani, Geoffrey L. Uy, Janusz Krawczyk, Harry P. Erba, Gabriel N Mannis, Chun Yew Fong, Florian Kuchenbauer, Mary-Elizabeth M. Percival, Jane L. Liesveld, William Blum, Brenda W Cooper, Alice Mims, Francesco Lanza, Jeroen J.W.M. Janssen, Juan Miguel Bergua Burgues, Tibor Kovacsovics, Norbert Vey, Martina V. Hemmer, Gaetano Bonifacio, Edwin Rock, Pau Montesinos
Journal: Blood
Blood (2024) 144 (Supplement 1): 733.
https://doi.org/10.1182/blood-2024-209097
Published: 2024
Journal Articles

Dose Optimization of Inotuzumab Ozogamicin in Adult Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia

Daniel J. DeAngelo, Ying Chen, Ryan D. Cassaday, Jennifer Hibma, Derek Z Yang, May Garrett, Fan Zhang, Svetoslav H Dimitrov, Erik Vandendries, Hagop M. Kantarjian
Journal: Blood
Blood (2024) 144 (Supplement 1): 732.
https://doi.org/10.1182/blood-2024-194244
Published: 2024
Journal Articles

Overall Survival and Duration of Treatment in Patients with Advanced Systemic Mastocytosis Receiving Avapritinib Versus Midostaurin or Best Available Therapy in a Real-World Setting

Andreas Reiter, Jason Gotlib, Iván Álvarez-Twose, Deepti H. Radia, Johannes Luebke, Priyanka J. Bobbili, Aolin Wang, Saša Dimitrijević, Erin Sullivan, Juliana Schwaab, Ilene A. Galinsky, Cecelia Perkins, Wolfgang R. Sperr, Priya Sriskandarajah, Manasi Mohan, Teshawna Badu, Mei Sheng Duh, Peter Valent, Daniel J. DeAngelo
Journal: Blood
Blood (2024) 144 (Supplement 1): 1801.
https://doi.org/10.1182/blood-2024-204015
Published: 2024
Journal Articles

Obecabtagene autoleucel (obe-cel) for Adult Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia (R/R B-ALL): Deep Molecular Remission May Predict Better Outcomes

Elias Jabbour, Jae H. Park, Paul Shaughnessy, Aaron C. Logan, Karamjeet S Sandhu, Mehrdad Abedi, Bijal D Shah, Michael R Bishop, Daniel J. DeAngelo, Pierre Lao-Sirieix, Wolfram Brugger, Martin A Pule, Yiyun Zhang, Claire Roddie
Journal: Blood
Blood (2024) 144 (Supplement 1): 963.
https://doi.org/10.1182/blood-2024-194508
Published: 2024
Journal Articles

Trial-in-Progress: A Phase 2 Study of Ruxolitinib in Low-Risk Essential Thrombocythemia and Polycythemia Vera Patients with High Symptom Burden

Chi-Joan How, Yiwen Liu, Kathleen Gallagher, Emma K Logan, Ann Mullally, Donna S. Neuberg, Thomas Reardon, Alyssa Watson, Daniel J. DeAngelo, Rushad Patell, Gabriela S. Hobbs
Journal: Blood
Blood (2024) 144 (Supplement 1): 6644.
https://doi.org/10.1182/blood-2024-194126
Published: 2024
Journal Articles

The Prognostic and Predictive Value of RUNX1 Mutations in Newly Diagnosed Acute Myeloid Leukemia - an International Multicenter Cohort Study

Rebecca P. Bystrom, Jan Philipp Bewersdorf, Yiwen Liu, Eva Johanna Schaefer, Rory M. Shallis, Leora Boussi, Andrius Zucenka, Sylvain Garciaz, Luis E. Aguirre, Daniel J. DeAngelo, Richard M. Stone, Marlise R. Luskin, Jacqueline S. Garcia, Eric S. Winer, Evan C. Chen, Martha Wadleigh, Kelly Ling, Eytan M. Stein, Aaron D. Goldberg, Amer M. Zeidan, Shai O. Shimony, Maximilian Stahl
Journal: Blood
Blood (2024) 144 (Supplement 1): 2947.
https://doi.org/10.1182/blood-2024-205581
Published: 2024
Journal Articles

Comparative Analysis of Outcomes with HMA Plus Venetoclax Vs Intensive Chemotherapy in AML Patients Harboring Very-High Risk Cytogenetics

Luis E. Aguirre, Jan Philipp Bewersdorf, Yiwen Liu, Rory M. Shallis, Leora Boussi, Andrius Zucenka, Sylvain Garciaz, Rebecca P. Bystrom, Daniel J. DeAngelo, Richard M. Stone, Marlise R. Luskin, Jacqueline S. Garcia, Eric S. Winer, Kelly Ling, Evan C. Chen, Martha Wadleigh, Eytan M. Stein, Aaron D. Goldberg, Amer M. Zeidan, Shai O. Shimony, Maximilian Stahl
Journal: Blood
Blood (2024) 144 (Supplement 1): 4267.
https://doi.org/10.1182/blood-2024-202744
Published: 2024
Journal Articles

Venetoclax-Based Therapy Versus Intensive Chemotherapy Followed By Allogeneic-Stem Cell Transplantation for High-Risk Elderly Acute Myeloid Leukemia

Alexandre Iat, Jan Philipp Bewersdorf, Julia Gilhodes, Yiwen Liu, Rory M. Shallis, Leora Boussi, Andrius Zucenka, Rebecca P. Bystrom, Daniel J. DeAngelo, Guillaume Berton, Amel Soua, Kelly Ling, Luis E. Aguirre, Richard M Stone, Marlise R. Luskin, Jacqueline S. Garcia, Eric S. Winer, Evan C. Chen, Martha Wadleigh, Aaron D. Goldberg, Amer M. Zeidan, Thomas Cluzeau, Shai O. Shimony, Maximilian Stahl, Sylvain Garciaz
Journal: Blood
Blood (2024) 144 (Supplement 1): 1508.
https://doi.org/10.1182/blood-2024-207045
Published: 2024
Journal Articles

Final Analysis of a Phase I Study of Escalating Doses of the BCL-2 Inhibitor Venetoclax in Combination with Daunorubcin/Cytarabine Induction and High Dose Cytarabine Consolidation in Previously Untreated Adults with Acute Myeloid Leukemia

Richard M Stone, Daniel J. DeAngelo, Anthony G. Letai, Ilene A. Galinsky, Howard Weiner, Austen Halpin, Lexi Noyes, Hunter Smith, Carter Lombardi, Rebecca Leonard, Geoffrey Fell, Yael Flammand, Jeremy Ryan, Marina Konopleva, Martha Wadleigh, Maximilian Stahl, Evan Chen, Virginia O. Volpe, Eric S. Winer, Jacqueline S. Garcia, Marlise R. Luskin, Anand Ashwin Patel
Journal: Blood
Blood (2024) 144 (Supplement 1): 4261.
https://doi.org/10.1182/blood-2024-203683
Published: 2024
Journal Articles

Randomized Phase II Trial of Dendritic Cell/AML Fusion Cell Vaccination Compared to Standard of Care Therapy in AML CR1

Prateek Pophali, Giulia Cheloni, Richard M. Stone, Kai W Wucherpfennig, Aric C. Hall, Amir T. Fathi, Lina Bisharat, Emma K Logan, Yiwen Liu, Donna S. Neuberg, Malgorzata McMasters, Jessica Liegel, Jacqueline S. Garcia, Daniel J. DeAngelo, Michele Narcis, Dina Stroopinsky, Pavania Elavalakanar, Ioannis S Vlachos, Ilene A. Galinsky, Jason Pyrdol, Georges Chedid, Dimitra Karagkouni, Shivani Nanda, Kathrine S Rallis, Isabella Saldarriaga, Hazal Toros, Haitham Abdelhakim, Amelia Langston, Joseph P. McGuirk, Donald Kufe, David Avigan, Jacalyn Rosenblatt
Journal: Blood
Blood (2024) 144 (Supplement 1): 4256.
https://doi.org/10.1182/blood-2024-200876
Published: 2024
Journal Articles

Addition of Inotuzumab to a Pediatric Inspired Chemotherapy Regimen in Young Adult Patients with B-Cell Acute Lymphoblastic Leukemia: Findings from the Alliance A041501 Phase 3 Randomized Trial

Daniel J. DeAngelo, Jun Yin, Anjali S. Advani, Selina Luger, Jill Fulcher, Michaela Liedtke, Geoffrey L. Uy, Shira N. Dinner, Lindsay Wilde, Marlise R. Luskin, Caner Saygin, Ella Postich, Noreen Fulton, Richard C. Harvey, Gaby E Perez Burbano, Rebecca Teske, Harry P. Erba, Mark R. Litzow, Richard M. Stone, Wendy Stock
Journal: Blood
Blood (2024) 144 (Supplement 1): 308.
https://doi.org/10.1182/blood-2024-209438
Published: 2024
Journal Articles

Assessment of Outcomes of Allogeneic Stem Cell Transplantation By Treatment Arm in Newly Diagnosed Measurable Residual Disease Negative Patients with B-Lineage Acute Lymphoblastic Leukemia Randomized to Conventional Chemotherapy +/- Blinatumomab in the ECOG-ACRIN E1910 Phase III National Clinical Trials Network Trial

Michaela Liedtke, Zhuoxin Sun, Mark R. Litzow, Ryan J Mattison, Elisabeth Paietta, Kathryn G. Roberts, Yanming Zhang, Janis Racevskis, Hillard M. Lazarus, Jacob M. Rowe, Daniel A. Arber, Julie Bergeron, Brent L. Wood, Yaqi Zhao, Gang Wu, Ti-Cheng Chang, Wenchao Zhang, Keith W. Pratz, Shira N. Dinner, Noelle Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L. Uy, Deepa Jeyakumar, Tara L. Lin, Cheryl L. Willman, Daniel J. DeAngelo, Shejal B. Patel, Michelle A Elliott, Anjali S. Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Bhave, Elad Sharon, Richard Little, Harry P. Erba, Richard M. Stone, Selina Luger, Charles G. Mullighan, Martin S. Tallman, Matthew J. Wieduwilt
Journal: Blood
Blood (2024) 144 (Supplement 1): 779.
https://doi.org/10.1182/blood-2024-207557
Published: 2024
Journal Articles

Frailty and Long-Term Survival Among Older Adults with Blood Cancers

Clark DuMontier, Angel Cronin, Tammy T Hshieh, Ameya Sanyal, Michelle Fredericks, Nicholas Groblewski, Lee Mozessohn, Daniel J DeAngelo, Richard M Stone, Robert J. Soiffer, Jane A Driver, Gregory A Abel
Journal: Blood
Blood (2024) 144 (Supplement 1): 448.
https://doi.org/10.1182/blood-2024-203896
Published: 2024