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Kai W Wucherpfennig
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Journal Articles

Advances in CD137-Enriched Adoptive T Cell Therapy for Acute Myeloid Leukemia Via Ex Vivo Immune Cell Priming with DC/AML Fusion Vaccine

Kathrine S Rallis, Jessica Liegel, Giulia Cheloni, Poorva Bindal, Isabella Saldarriaga, Junyan Zhang, Georges Chedid, Joseph Abirached, Jonah Lee, John G. Clohessy, Samprity Ankita, Rajeev Relangi, Lina Bisharat, Hazal Toros, Sophia Adamia, Jasper B Lee, Donald Kufe, Kai W Wucherpfennig, Jacalyn Rosenblatt, David Avigan
Journal: Blood
Blood (2024) 144 (Supplement 1): 4817.
https://doi.org/10.1182/blood-2024-208563
Published: 2024
Journal Articles

Randomized Phase II Trial of Dendritic Cell/AML Fusion Cell Vaccination Compared to Standard of Care Therapy in AML CR1

Prateek Pophali, Giulia Cheloni, Richard M. Stone, Kai W Wucherpfennig, Aric C. Hall, Amir T. Fathi, Lina Bisharat, Emma K Logan, Yiwen Liu, Donna S. Neuberg, Malgorzata McMasters, Jessica Liegel, Jacqueline S. Garcia, Daniel J. DeAngelo, Michele Narcis, Dina Stroopinsky, Pavania Elavalakanar, Ioannis S Vlachos, Ilene A. Galinsky, Jason Pyrdol, Georges Chedid, Dimitra Karagkouni, Shivani Nanda, Kathrine S Rallis, Isabella Saldarriaga, Hazal Toros, Haitham Abdelhakim, Amelia Langston, Joseph P. McGuirk, Donald Kufe, David Avigan, Jacalyn Rosenblatt
Journal: Blood
Blood (2024) 144 (Supplement 1): 4256.
https://doi.org/10.1182/blood-2024-200876
Published: 2024
Journal Articles

Targeting of the CD161 inhibitory receptor enhances T-cell–mediated immunity against hematological malignancies

Francesca Alvarez Calderon, Byong H. Kang, Oleksandr Kyrysyuk, Shiwei Zheng, Hao Wang, Nathan D. Mathewson, Adrienne M. Luoma, Xiaohan Ning, Jason Pyrdol, Xuan Cao, Mario L. Suvà, Guo-Cheng Yuan, K. Dane Wittrup, Kai W. Wucherpfennig
Journal: Blood
Blood (2024) 143 (12): 1124–1138.
https://doi.org/10.1182/blood.2023022882
Published: 2024
Includes: Supplemental data
Journal Articles

4-1bb Enrichment Enhances Adoptive T Cell Therapy for Hematological Malignancies Using a Novel Approach for Ex Vivo Immune Cell Priming with DC/Tumor Fusion Vaccine

Kathrine S Rallis, Jessica Liegel, Giulia Cheloni, Poorva Bindal, Isabella Saldarriaga, Junyan Zhang, Georges Chedid, Joseph Abirached, John G. Clohessy, Sophia Adamia, Kai W Wucherpfennig, Donald Kufe, Jacalyn Rosenblatt, David Avigan
Journal: Blood
Blood (2023) 142 (Supplement 1): 2066.
https://doi.org/10.1182/blood-2023-182381
Published: 2023
Journal Articles

Inhibition of MICA and MICB Shedding Enhances Cytokine-Induced Memory-like NK Cell-Mediated Activity Against Multiple Myeloma

Sabrin Tahri, Nang Kham Su, Luisa Maria Lampe, Han Dong, Juliana Vergara Cadavid, Natalie Papazian, Amanda Cao, Jean-Baptiste Alberge, Lucas Ferrari de Andrade, Mahshid Rahmat, Yujia Shen, Rebecca Boiarsky, Laura Blanco, Bruno Paiva, Andreas Guenther, Gad Getz, Pieter Sonneveld, Tom Cupedo, Kai W. Wucherpfennig, Irene Ghobrial, Rizwan Romee
Journal: Blood
Blood (2022) 140 (Supplement 1): 4204–4206.
https://doi.org/10.1182/blood-2022-164811
Published: 2022
Journal Articles

MICA/B antibody induces macrophage-mediated immunity against acute myeloid leukemia

Pedro Henrique Alves da Silva, Samantha Xing, Andriana G. Kotini, Eirini P. Papapetrou, Xiaoyu Song, Kai W. Wucherpfennig, John Mascarenhas, Lucas Ferrari de Andrade
Journal: Blood
Blood (2022) 139 (2): 205–216.
https://doi.org/10.1182/blood.2021011619
Published: 2022
Includes: Supplemental data
Journal Articles

Dual Chimeric Antigen Receptor Approach Combining Novel Tumor Targeting Strategies Circumvents Antigen Escape in Multiple Myeloma

John Reiser, Ketan Mathavan, Sajid Mahmood, Yijia Pan, Bryan Hancock, Robert Blum, Wen-I Yeh, Andrew Houk, Chia-Wei Chang, Tom Lee, Uta Hopken, John Goulding, Armin Rehm, Kai W. Wucherpfennig, Jode P Goodridge, Ryan Bjordahl, Bahram Valamehr
Journal: Blood
Blood (2021) 138 (Supplement 1): 1718.
https://doi.org/10.1182/blood-2021-154025
Published: 2021
Journal Articles

Mechanical Checkpoint Regulates Monocyte Differentiation in Fibrotic Matrix

Kyle H Vining, Anna E. Marneth, Kwasi Adu-Berchie, Christina M. Tringides, Joshua M Grolman, Yutong Liu, Waihay J. Wong, Olga Pozdnyakova, Mariano Severgnini, Alexander Stafford, Georg N. Duda, Ann Mullally, Kai W. Wucherpfennig, David J Mooney
Journal: Blood
Blood (2021) 138 (Supplement 1): 2539.
https://doi.org/10.1182/blood-2021-147297
Published: 2021
Journal Articles

Development of a Novel MICA/B-Specific CAR As a Pan-Tumor Targeting Strategy for Off-the-Shelf, Cell-Based Cancer Immunotherapy

Ryan Bjordahl, PhD, John Goulding, PhD, Mochtar Pribadi, PhD, Robert Blum, MS, Chiawei Chang, Yijia Pan, PhD, Lucas Ferrari de Andrade, PhD, Kai W. Wucherpfennig, Yu-Waye Chu, MD, Hui-yi Chu, PhD, Wen-I Yeh, PhD, Svetlana Gaidarova, MS, Ellen Liu, PhD, Shohreh Sikaroodi, PhD, Lauren Fong, PhD, Janel Huffman, MS, Tom Lee, PhD, Bahram Valamehr, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–6.
https://doi.org/10.1182/blood-2020-141095
Published: 2020
Journal Articles

Immune-Tumor Interactions in Resistance to Cancer Immunotherapy

Kai W. Wucherpfennig, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): SCI-45.
https://doi.org/10.1182/blood-2019-121065
Published: 2019
Journal Articles

The shared tumor-associated antigen cytochrome P450 1B1 is recognized by specific cytotoxic T cells

Britta Maecker, David H. Sherr, Robert H. Vonderheide, Michael S. von Bergwelt-Baildon, Naoto Hirano, Karen S. Anderson, Zhinan Xia, Marcus O. Butler, Kai W. Wucherpfennig, Carl O'Hara, Geoffrey Cole, Silvia S. Kwak, Urban Ramstedt, Andy J. Tomlinson, Roman M. Chicz, Lee M. Nadler, Joachim L. Schultze
Journal: Blood
Blood (2003) 102 (9): 3287–3294.
https://doi.org/10.1182/blood-2003-05-1374
Published: 2003
Journal Articles

Human primary and memory cytotoxic T lymphocyte responses are efficiently induced by means of CD40-activated B cells as antigen-presenting cells: potential for clinical application

Michael S. von Bergwelt-Baildon, Robert H. Vonderheide, Britta Maecker, Naoto Hirano, Karen S. Anderson, Marcus O. Butler, Zhinan Xia, Wan Y. Zeng, Kai W. Wucherpfennig, Lee M. Nadler, Joachim L. Schultze
Journal: Blood
Blood (2002) 99 (9): 3319–3325.
https://doi.org/10.1182/blood.V99.9.3319
Published: 2002