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Journal Articles

Discovery of the Unique GMP-Grade iPSC Clones That Give Rise to Functional, High Purity, Matured CD8 Alpha Beta T or Gamma Delta T with Exponential Expansion Capacity

Ying-Tsen Tung, Chih-Lung Chen, Annie Yi-Ting Lai, Chien-Yu Hsu, Chien-Hsi Chen, Po-Fan Chu, Lin-Yu Liao, Tzu-Chien Kuo, Chieh-Teng Cheng, Chun-Yu Lin, Wan-Chen Tsai, Wei-Ting Chen, Darien Zhing Herr Chan, Hsin-Hua Cho, Cheng-Kai Wang, Yo-Chuen Lin, Jin-Yi Lu, Lee-Yieng Lim, Jhang-Sian Yu, Ming-Chin Ko, Chia-Hung Lin, Yi-Han Dai, I-Ting Chen, Fang-Pei Chang, Shao-Ju Weng, Ting-Yi Wu, Yuan-Yu Hsia, Fu-Fei Hsu, Lillian Yi-Ting Lai, Shiou-Ling Jian, Shih-Wen Huang, Yu-Chih Peng, Ke-Hsun Hsu, Liang-Yi Chen, Ji-Kuan Wang, Yao-Yu Chen, Chih-Kai Yin, Yi-Hung Ou, Min-Ren Chiang, Wen-Hao Wang, Tsung-Hao Yeh, Xiaming Peng, Yang Shi, Pei Zhang, Ya-Chu Yu, Yun Gao, Yen-Hsien Lee, Pei-Chun Wu, Ta-Hsun Liao, De-Kuan Chang, Lien-Szu Wu, Jen-Chih Chi, Ching-Ying Huang, Alex Shih-Min Huang
Journal: Blood
Blood (2024) 144 (Supplement 1): 7195.
https://doi.org/10.1182/blood-2024-203106
Published: 2024
Journal Articles

Clinical Application for Modification of the 2022 European Leukemianet Genetic Risk Stratification in Pediatric Acute Myeloid Leukemia

Shih-Hsiang Chen, Ting-Chi Yeh, Tang-Her Jaing, Shih-Chung Wang, Hsi-Che Liu, Fang-Liang Huang, Yu-Chieh Chen, Jen-Yin Hou, Jiunn-Ming Sheen, Pei-Chin Lin, Chih-Ying Lee, Tsung-Yen Chang, Shang-Hsien Yang, Wei-Hao Wang, Shu-Huey Chen, Hsiao-Wen Kao, Shyh-Shin Chiou, Chih-Cheng Hsiao, Ming-Chung Kuo, Chao-Ping Yang, Lee-Yung Shih
Journal: Blood
Blood (2024) 144 (Supplement 1): 4313.
https://doi.org/10.1182/blood-2024-201637
Published: 2024
Journal Articles

iPSC-Derived CAR-Gamma Delta T with Novel Combinatorial KO Demonstrated Extended Longevity and Profound Anti-Tumor Efficacy without Cytokine Support in Preclinical Studies

Jhang-Sian Yu, Chia-Hung Lin, Ying-Tsen Tung, Fang-Pei Chang, Edward Po-Fan Chu, Shiou-Ling Jian, Fu-Fei Hsu, Ming-Chin Ko, Yi-Han Dai, Chieh-Teng Cheng, Tzu-Chien Kuo, I-Ting Chen, Ting-Yi Wu, Jin-Yi Lu, Ke-Hsun Hsu, Wei-Ting Chen, Darien Zhing Herr Chan, Yi-Ting Lai, Shao-Ju Weng, Liang-Yi Chen, Yuan-Yu Hsia, Yi-Hung Ou, Yo-Chuen Lin, Shih-Wen Huang, Yu-Chih Peng, Chien-Hsi Chen, Chien-Yu Hsu, Yi-Ting Lai, Chih-Lung Chen, Chun-Yu Lin, Lin-Yu Liao, Wan-Chen Tsai, Hsin-Hua Cho, Cheng-Kai Wang, Lee-Yieng Lim, Ji-Kuan Wang, Yao-Yu Chen, Chih-Kai Yin, Wen-Hao Wang, Tsung-Hao Yeh, Min-Ren Chiang, Ruyue Ji, Jen-Chih Chi, Lien-Szu Wu, Jennifer Huang, De-Kuan Chang, Alex Shih-Min Huang
Journal: Blood
Blood (2024) 144 (Supplement 1): 4790.
https://doi.org/10.1182/blood-2024-205086
Published: 2024
Journal Articles

Foxo1 is an iron-responsive transcriptional factor regulating systemic iron homeostasis

Teng Xu, Xu Zhang, Wenting Zhao, Jiaxin Shi, Sitong Wan, Yan Zhang, Yanling Hao, Mingyue Sun, Jingjing He, Li Jiang, Hao Wang, Hong Gao, Junjie Luo, Yongting Luo, Peng An
Journal: Blood
Blood (2024) 144 (12): 1314–1328.
https://doi.org/10.1182/blood.2024024293
Published: 2024
Includes: Supplemental data
Journal Articles

Targeting of the CD161 inhibitory receptor enhances T-cell–mediated immunity against hematological malignancies

Francesca Alvarez Calderon, Byong H. Kang, Oleksandr Kyrysyuk, Shiwei Zheng, Hao Wang, Nathan D. Mathewson, Adrienne M. Luoma, Xiaohan Ning, Jason Pyrdol, Xuan Cao, Mario L. Suvà, Guo-Cheng Yuan, K. Dane Wittrup, Kai W. Wucherpfennig
Journal: Blood
Blood (2024) 143 (12): 1124–1138.
https://doi.org/10.1182/blood.2023022882
Published: 2024
Includes: Supplemental data
Journal Articles

Discovery of BT-114143, a Novel and Potent Small-Molecule Plasminogen Inhibitor for Hyperfibrinolysis

Jun Tang, Sen Ji, Xiao Hu, Yan Wang, Jun Qi, Xiao Wang, Hao Wang, Jianzong Li, Zhiqiang Li, Min Li, Shaomei Zeng, Xiong Yuan, Xiaodong Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 1229.
https://doi.org/10.1182/blood-2023-185454
Published: 2023
Journal Articles

TREM2 acts as a receptor for IL-34 to suppress acute myeloid leukemia in mice

Xiaoling Xie, Wuju Zhang, Min Xiao, Tiantian Wei, Yingqi Qiu, Jingyang Qiu, Hao Wang, Zeyou Qiu, Sheng Zhang, Yating Pan, Linlin Mao, Yuhua Li, Bin Guo, Wanwen Yang, Yuxing Hu, Shujie Hu, Yan Gong, Jun Yang, Guozhi Xiao, Yue Zhang, Xiaochun Bai
Journal: Blood
Blood (2023) 141 (26): 3184–3198.
https://doi.org/10.1182/blood.2022018619
Published: 2023
Includes: Supplemental data
Journal Articles

Impacts of Total Body Irradiation in Allogeneic Umbilical Cord Blood Hematopoietic Stem Cell Transplantation

Jeffrey J. Pu, Kristin N. Berger, Hao Wang, Wei Fu, Elizabeth L Miller, Larisa Broglie, Heiko Konig, Frederick Goldman, Julie-An Talano, Sherif S. Farag, Melanie Comito
Journal: Blood
Blood (2021) 138 (Supplement 1): 4852.
https://doi.org/10.1182/blood-2021-152893
Published: 2021
Journal Articles

RNF217 regulates iron homeostasis through its E3 ubiquitin ligase activity by modulating ferroportin degradation

Li Jiang, Jiaming Wang, Kai Wang, Hao Wang, Qian Wu, Cong Yang, Yingying Yu, Pu Ni, Yueyang Zhong, Zijun Song, Enjun Xie, Ronggui Hu, Junxia Min, Fudi Wang
Journal: Blood
Blood (2021) 138 (8): 689–705.
https://doi.org/10.1182/blood.2020008986
Published: 2021
Includes: Supplemental data
Journal Articles

Prognostic Factors for North American Adult T Cell Leukemia Lymphoma: Defining Risk Groups Using a Four-Point Score Prognostic System

Shafia Rahman, MD, Alvaro Alvarez Soto, MD, Lindor Qunaj, MD, Kenny Ye, Kith Pradhan, PhD, Astha Thakkar, MBBS, Zhu Cui, MD, Michal Kasher Meron, Angelica D'Aiello, Amanda Lombardo, PA-C, BS, MS, Jennat Mustafa, PA-C, Fariha Khatun, PA-C, Kailyn Gillick, PA-C, Felisha Joseph, PA-C, Anjali Naik, PA-C, Alyssa De Castro, PharmD, Ulrich G. Steidl, MDPhD, Hao Wang, MS, Xiaoxin Ren, Xingxing Zang, PhD, Olga Derman, MD, Kira Gritsman, MDPhD, Noah Kornblum, MD, Aditi Shastri, MD, Ioannis Mantzaris, MD MS, Mendel Goldfinger, MD, Ira Braunschweig, MD, B. Hilda Ye, PhD, Amit Verma, MBBS, Murali Janakiram, MD, Urvi A Shah, MD, R. Alejandro Sica, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38–39.
https://doi.org/10.1182/blood-2020-141428
Published: 2020
Journal Articles

Effects of MiR-451a on the Phagocytosis and Polarization of Macrophages

Xiaoli Liu, postgraduate, Dongyue Zhang, postgraduate, Hao Wang, PhD candidate, Qian Ren, Lina Wang, PhD, Weiping Yuan, PhDMD, Guoguang Zheng, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42.
https://doi.org/10.1182/blood-2020-140250
Published: 2020
Journal Articles

Dynamics of Leukocyte Subpopulations Reconstitution Predict Infection Propensity in a Multiethnic Real World Cohort Treated with Anti-CD19 CAR-T Cell Therapy (Axicabtagene-Ciloleucel)

Astha Thakkar, MBBS, Zhu Cui, MD, Stephen Zachary Peeke, MD, Nishi Shah, MBBS, MPH, Amanda Lombardo, PA-C, BS, MS, Fariha Khatun, PA-C, Jennat Mustafa, PA-C, Alyssa De Castro, PharmD, Kailyn Gillick, PA-C, Felisha Joseph, PA-C, Anjali Naik, PA-C, Shafia Rahman, MD, Angelica D'Aiello, Richard Elkind, PA-C, MS, Susan Sakalian, Karen Fehn, RN, BSN, Karen Wright, RN-BC, MS, OCN, BMTCN, Michelly Abreu, ANP,MSN, Latoya Townsend Nugent, NP, Nicole Chambers, ANP/FNP, Rosmi Mathew, FNP-BC, Donika Binakaj, BBA, Randin Nelson, MD, Carlo Palesi, Monika Paroder, MD, Joan Uehlinger, MD, Yanhua Wang, MD PhD, Yang Shi, MD PhD, Xingxing Zang, PhD, Hao Wang, MS, Christopher Nishimura, BS, Xiaoxin Ren, Ulrich G. Steidl, MDPhD, Kira Gritsman, MDPhD, Murali Janakiram, Noah Kornblum, MD, Olga Derman, MD, Ioannis Mantzaris, MD MS, Aditi Shastri, MD, Rachel Bartash, MD, Yoram Puius, MD PhD, Margaret McCort, MD, Mendel Goldfinger, MD, Lizamarie Bachier-Rodriguez, MD, Amit Verma, MBBS, Ira Braunschweig, MD, R. Alejandro Sica, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
https://doi.org/10.1182/blood-2020-139533
Published: 2020
Journal Articles

The Safety and Efficacy of a CRISPR/Cas9-Engineered Universal CAR-T Cell Product (CTA101) in Patients with Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia

Yongxian Hu, MD, Yali Zhou, Mingming Zhang, MD, Wengang Ge, Yi Li, MD, Li Yang, MD, Guoqing Wei, MD, Lu Han, Hao Wang, Xingwang Zhang, PhD, Jiangtao Ren, PhD, He Huang, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 52.
https://doi.org/10.1182/blood-2020-142262
Published: 2020
Journal Articles

Hepatic transferrin plays a role in systemic iron homeostasis and liver ferroptosis

Yingying Yu, Li Jiang, Hao Wang, Zhe Shen, Qi Cheng, Pan Zhang, Jiaming Wang, Qian Wu, Xuexian Fang, Lingyan Duan, Shufen Wang, Kai Wang, Peng An, Tuo Shao, Raymond T. Chung, Shusen Zheng, Junxia Min, Fudi Wang
Journal: Blood
Blood (2020) 136 (6): 726–739.
https://doi.org/10.1182/blood.2019002907
Published: 2020
Includes: Supplemental data
Journal Articles

Effects of Overexpressed P2X7 on Leukemia Progression in Mouse Acute Myeloid Leukemia Model

Wenli Feng, PhD, Xiao Yang, PhD, Rong Wang, PhD, Feifei Yang, PhD, Hao Wang, PhD candidate, Xiaoli Liu, PhD candidate, Lina Wang, PhD, Guoguang Zheng, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5141.
https://doi.org/10.1182/blood-2018-99-110896
Published: 2018
Journal Articles

Recombinant Human Thrombopoietin Increases Platelet Numbers and Reduces the Risk of Bleeding Events in Thrombocytopenic Patients with Chronic Hepatitis B Virus Infection: A Multicenter Observational Study

Wan-Yi Zhai, Ru Feng, Xiao-Lu Zhu, Yun He, Hai-Xia Fu, Yi Liu, Jian-Liang Shen, Qian Jiang, MD, Hao Jiang, Jin Lu, Qian-Ming Wang, Jing-Wen Wang, Hui Liu, Hao Wang, Hui Ma, Yan-Di Xie, Lan-Ping Xu, Kai-Yan Liu, Xiao-Jun Huang, Xiaohui Zhang, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4990.
https://doi.org/10.1182/blood-2018-99-116000
Published: 2018
Journal Articles

Immunosuppressive Treatment Combined with Nucleoside Analogues Is Superior to Nucleoside Analogues Alone in the Treatment of Severe Thrombocytopenia in Patients with Cirrhosis-Associated with Hepatitis B in China: A Multicenter, Observational Study

Xiao-Hui Zhang, MD, PhD, Ru Feng, Lan-ping Xu, Qian Jiang, Hao Jiang, Hai-xia Fu, Hui Liu, Ting Niu, Xin Wang, Jian-da Hu, Ming Jiang, Zhao Wang, Jing-wen Wang, Hui Ma, Yan-di Xie, Xiao-lu Zhu, Hao Wang, Lai Wei, Xiao Jun Huang
Journal: Blood
Blood (2014) 124 (21): 2778.
https://doi.org/10.1182/blood.V124.21.2778.2778
Published: 2014
Journal Articles

Constitutive Activation of Shp2 Cooperates with MLL1 Fusion Proteins to Increase Expression of the Homeodomain Transcription Factors Cdx4, HoxA9 and HoxA10

Ling Bei, MD, Chirag Shah, PhD, Hao Wang, PhD, Elizabeth Eklund, MD
Journal: Blood
Blood (2014) 124 (21): 3537.
https://doi.org/10.1182/blood.V124.21.3537.3537
Published: 2014
Journal Articles

Eradication of non-Hodgkin lymphoma through the induction of tumor-specific T-cell immunity by CD20-Flex BiFP

Lei Zhao, Qin Tong, Weizhu Qian, Bohua Li, Dapeng Zhang, Tuo Fu, Shuyan Duan, Xueguang Zhang, Jian Zhao, Jianxin Dai, Hao Wang, Sheng Hou, Yajun Guo
Journal: Blood
Blood (2013) 122 (26): 4230–4236.
https://doi.org/10.1182/blood-2013-04-496554
Published: 2013
Includes: Supplemental data
Journal Articles

Increased Expression Of Fgf2 Induces Cytokine Hypersensitivity In Leukemia Stem Cells With Translocations Involving The MLL Gene

Chirag Shah, PhD, Hao Wang, PhD, Ling Bei, MD, Elizabeth Eklund, MD
Journal: Blood
Blood (2013) 122 (21): 3791.
https://doi.org/10.1182/blood.V122.21.3791.3791
Published: 2013