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Journal Articles

GSDME-mediated pyroptosis contributes to chemotherapy-induced platelet hyperactivity and thrombotic potential

Ruyi Xue, Min Li, Ge Zhang, Wei Zhang, Liping Han, Tao Bo, Haoxuan Zhong, Dingjin Yao, Yiran Deng, She Chen, Si Zhang
Journal: Blood
Blood (2024) 144 (25): 2652–2665.
https://doi.org/10.1182/blood.2023023179
Published: 2024
Includes: Supplemental data
Journal Articles

Discovery of BT-114143, a Novel and Potent Small-Molecule Plasminogen Inhibitor for Hyperfibrinolysis

Jun Tang, Sen Ji, Xiao Hu, Yan Wang, Jun Qi, Xiao Wang, Hao Wang, Jianzong Li, Zhiqiang Li, Min Li, Shaomei Zeng, Xiong Yuan, Xiaodong Zhang
Journal: Blood
Blood (2023) 142 (Supplement 1): 1229.
https://doi.org/10.1182/blood-2023-185454
Published: 2023
Journal Articles

Targeting PRMT9 Elicits Cgas-Mediated Anti-Leukemia Immunity

Haojie Dong, Xin He, Lei Zhang, Wei Chen, Yichun Lin, Songbai Liu, Huafeng Wang, Wenfeng Huang, Sierra Min Li, Yinghui Zhu, Dandan Zhao, Lucy Ghoda, Rui Su, Jianjun Chen, Ritin Sharma, Patrick Pirrotte, Xiwei Wu, Weidong Hu, Weidong Han, Binghui Shen, Ya-Huei Kuo, Jie Jin, Amandeep Salhotra, Jeffrey Wang, Guido Marcucci, Yun Luo, Ling Li
Journal: Blood
Blood (2022) 140 (Supplement 1): 4931–4933.
https://doi.org/10.1182/blood-2022-167366
Published: 2022
Journal Articles

Disruption of dNTP homeostasis by ribonucleotide reductase hyperactivation overcomes AML differentiation blockade

Hanying Wang, Xin He, Lei Zhang, Haojie Dong, Feiteng Huang, Jie Xian, Min Li, Wei Chen, Xiyuan Lu, Khyatiben V. Pathak, Wenfeng Huang, Zheng Li, Lianjun Zhang, Le Xuan Truong Nguyen, Lu Yang, Lifeng Feng, David J. Gordon, Jing Zhang, Patrick Pirrotte, Chun-Wei Chen, Amandeep Salhotra, Ya-Huei Kuo, David Horne, Guido Marcucci, David B. Sykes, Stefano Tiziani, Hongchuan Jin, Xian Wang, Ling Li
Journal: Blood
Blood (2022) 139 (26): 3752–3770.
https://doi.org/10.1182/blood.2021015108
Published: 2022
Includes: Supplemental data
Journal Articles

Anticoagulation targeting membrane-bound anionic phospholipids improves outcomes of traumatic brain injury in mice

Xinlong Dong, Wei Liu, Yu Shen, Katie Houck, Mengchen Yang, Yuan Zhou, Zilong Zhao, Xiaoping Wu, Teri Blevins, Amanda L. Koehne, Tze-Chein Wun, Xiaoyun Fu, Min Li, Jianning Zhang, Jing-fei Dong
Journal: Blood
Blood (2021) 138 (25): 2714–2726.
https://doi.org/10.1182/blood.2021011310
Published: 2021
Includes: Supplemental data
Journal Articles

Conformation-dependent blockage of activated VWF improves outcomes of traumatic brain injury in mice

Xin Xu, Chenyu Wang, Yingang Wu, Katie Houck, Tristan Hilton, Ashley Zhou, Xiaoping Wu, Cha Han, Mengchen Yang, Wei Yang, Fu-Dong Shi, Moritz Stolla, Miguel A. Cruz, Min Li, Jianning Zhang, Jing-fei Dong
Journal: Blood
Blood (2021) 137 (4): 544–555.
https://doi.org/10.1182/blood.2020007364
Published: 2021
Includes: Supplemental data
Journal Articles

FLT3 inhibition upregulates HDAC8 via FOXO to inactivate p53 and promote maintenance of FLT3-ITD + acute myeloid leukemia

Jun Long, Ming-Yuan Jia, Wei-Yue Fang, Xin-Jie Chen, Li-Li Mu, Zhong-Yu Wang, Yan Shen, Ru-Fang Xiang, Li-Ning Wang, Ling Wang, Chuan-He Jiang, Jie-Ling Jiang, Wen-Jun Zhang, Yi-Dan Sun, Li Chang, Wen-Hui Gao, Ying Wang, Jun-Min Li, Deng-Li Hong, Ai-Bin Liang, Jiong Hu
Journal: Blood
Blood (2020) 135 (17): 1472–1483.
https://doi.org/10.1182/blood.2019003538
Published: 2020
Includes: Supplemental data
Journal Articles

Role of HDAC8 Upregulation in Resistance of FLT3-ITD AML Stem Cells to FLT3 Inhibitors

Jun Long, Mingyuan Jia, Weiyue Fang, Xinjie Chen, Zhongyu Wang, Lili Mu, Rufang Xiang, Jun-Min LI, MD PhD, Dengli Hong, PhD, Aibin Liang, MD PhD, Jiong Hu, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1268.
https://doi.org/10.1182/blood-2019-128394
Published: 2019
Journal Articles

Dynamic Analysis of Cytokine Profile for Cytokine Release Syndrome in Multiple Myeloma Patients after CAR-T Cell Therapy

Shuangshuang Yang, MD, Lijuan Chen, MD PhD, Jie Xu, MD PhD, Frank Xiao-Hu Fan, MD PhD, Sun Yan, PhD, Wen Wu, MD PhD, Yan Wang, MD, Jin Wang, MD PhD, Shiwei Jin, MD, Yuebo Zhou, Yuanfang Liu, MD PhD, Yan Zhuang, PhD, Wu Zhang, PhD, Jun-Min Li, Jian Hou, PhD MD, Jian-Yong Li, MD PhD, Zhu Chen, PhD, Jian-Qing Mi, MD PhD, Sai-Juan Chen, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5617.
https://doi.org/10.1182/blood-2019-131799
Published: 2019
Journal Articles

Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL -rearranged acute lymphoblastic leukemia

Yinghui Zhu, Xin He, Yi-Chun Lin, Haojie Dong, Lei Zhang, Xianwei Chen, Zhihao Wang, Yudao Shen, Min Li, Hanying Wang, Jie Sun, Le Xuan Nguyen, Han Zhang, Wenjuan Jiang, Yanzhong Yang, Jianjun Chen, Markus Müschen, Chun-Wei Chen, Marina Y. Konopleva, Weili Sun, Jian Jin, Nadia Carlesso, Guido Marcucci, Yun Luo, Ling Li
Journal: Blood
Blood (2019) 134 (15): 1257–1268.
https://doi.org/10.1182/blood.2019002457
Published: 2019
Includes: Supplemental data
Journal Articles

PRMT1-mediated FLT3 arginine methylation promotes maintenance of FLT3-ITD + acute myeloid leukemia

Xin He, Yinghui Zhu, Yi-Chun Lin, Min Li, Juan Du, Haojie Dong, Jie Sun, Lei Zhu, Hanying Wang, Zonghui Ding, Lei Zhang, Lianjun Zhang, Dandan Zhao, Zhihao Wang, Herman Wu, Han Zhang, Wenjuan Jiang, Yang Xu, Jian Jin, Yudao Shen, Jeff Perry, Xinyang Zhao, Bin Zhang, Songbai Liu, Sheng-Li Xue, Binghui Shen, Chun-Wei Chen, Jianjun Chen, Samer Khaled, Ya-Huei Kuo, Guido Marcucci, Yun Luo, Ling Li
Journal: Blood
Blood (2019) 134 (6): 548–560.
https://doi.org/10.1182/blood.2019001282
Published: 2019
Includes: Supplemental data
Journal Articles

PRMT1 Mediated FLT3 Methylation As a Therapeutic Vulnerability in FLT3-ITD + AML

Xin He, PhD, Yinghui Zhu, PhD, Haojie Dong, PhD, Sierra Min Li, Zonghui Ding, PhD, Jie Sun, PhD, Juan Du, MDPhD, Hanying Wang, PhD, Lianjun Zhang, PhD, Yudao Shen, PhD, Hairui Su, BS, PhD, Samer K. Khaled, MD, Dandan Zhao, MD, Lei Zhang, PhD, Robert Hickey, Bin Zhang, PhD, Ya-Huei Kuo, PhD, Xinyang Zhao, PhD, Jian Jin, PhD, Nadia Carlesso, MD PhD, Jianjun Chen, PhD, Yang Xu, MD, Guido Marcucci, Ling Li, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 760.
https://doi.org/10.1182/blood-2018-99-112766
Published: 2018
Journal Articles

Identification of Individualized Minimal Residual Disease in Acute Myeloid Leukemia By Flow Cytometry and Its Application of Prognostic Significance

Jing-Ni Sui, Qiu-Sheng Chen, Yun-Xiang Zhang, Yan Sheng, Jing Wu, Jun-Min Li, Jiong Hu, MD, Xiang-Qin Weng, Bing Chen, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1522.
https://doi.org/10.1182/blood-2018-99-112367
Published: 2018
Journal Articles

von Willebrand factor enhances microvesicle-induced vascular leakage and coagulopathy in mice with traumatic brain injury

Yingang Wu, Wei Liu, Yuan Zhou, Tristan Hilton, Zilong Zhao, Wei Liu, Min Wang, Jason Yeon, Katie Houck, Perumal Thiagarajan, Fangyi Zhang, Fu-Dong Shi, Xiaoping Wu, Min Li, Jing-fei Dong, Jianning Zhang
Journal: Blood
Blood (2018) 132 (10): 1075–1084.
https://doi.org/10.1182/blood-2018-03-841932
Published: 2018
Includes: Supplemental data
Journal Articles

Lactadherin promotes microvesicle clearance to prevent coagulopathy and improves survival of severe TBI mice

Yuan Zhou, Wei Cai, Zilong Zhao, Tristan Hilton, Min Wang, Jason Yeon, Wei Liu, Fangyi Zhang, Fu-Dong Shi, Xiaoping Wu, Perumal Thiagarajan, Min Li, Jianning Zhang, Jing-fei Dong
Journal: Blood
Blood (2018) 131 (5): 563–572.
https://doi.org/10.1182/blood-2017-08-801738
Published: 2018
Includes: Supplemental data
Journal Articles

Favorable Impact of Allogeneic Stem Cell Transplantation in Patients with Therapy-Related Myelodysplasia Regardless of TP53 Mutational Status

Ryotaro Nakamura, MD, Ibrahim Aldoss, MD, Anh Pham, Sierra Min Li, Ketevan Gendzekhadze, PhD, Michelle Afkhami, MD, Milhan Telatar, Hao Hong, Abbas Padeganeh, Victoria Bedell, Thai Cao, MD, Samer Khaled, MD, Monzr M. Al Malki, MD, Amandeep Salhotra, MD, Haris Ali, MD, Ahmed Aribi, MD, Joycelynne M. Palmer, PhD, Patricia Aoun, MD, Ricardo Spielberger, MD, Anthony S. Stein, MD, David S. Snyder, MD, Margaret R. O'Donnell, MD, Joyce Murata-Collins, PhD, David Senitzer, PhD, Dennis D. Weisenburger, MD, Stephen J. Forman, MD FACP, Vinod Pullarkat, MD MRCP, Guido Marcucci, MD, Raju Pillai, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4248.
https://doi.org/10.1182/blood.V130.Suppl_1.4248.4248
Published: 2017
Journal Articles

Mutation Profiling and Associated Clinical Features in Chinese Cytogenetically Normal Acute Myeloid Leukemia Patients

Shu Wang, Yun-Xiang Zhang, Ting Huang, Kankan Wang, PhD, Jun-Min LI, MD PhD, Jin-yan Huang, PhD, Bing Chen, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5102.
https://doi.org/10.1182/blood.V130.Suppl_1.5102.5102
Published: 2017
Journal Articles

The hepatocyte-specific HNF4α/miR-122 pathway contributes to iron overload–mediated hepatic inflammation

Min Li, Yuxiao Tang, Lusha Wu, Fengfeng Mo, Xin Wang, Hongxia Li, Ruirui Qi, Hongwei Zhang, Arun Srivastava, Chen Ling
Journal: Blood
Blood (2017) 130 (8): 1041–1051.
https://doi.org/10.1182/blood-2016-12-755967
Published: 2017
Includes: Supplemental data
Journal Articles

Cardiolipin-mediated procoagulant activity of mitochondria contributes to traumatic brain injury–associated coagulopathy in mice

Zilong Zhao, Min Wang, Ye Tian, Tristan Hilton, Breia Salsbery, Eric Z. Zhou, Xiaoping Wu, Perumal Thiagarajan, Eric Boilard, Min Li, Jianning Zhang, Jing-fei Dong
Journal: Blood
Blood (2016) 127 (22): 2763–2772.
https://doi.org/10.1182/blood-2015-12-688838
Published: 2016
Includes: Supplemental data
Journal Articles

Clinical Significance of Co-Existence of PHF6 and NOTCH1 mutations in Adult T-Cell Acute Lymphoblastic Leukemia

Zheng Ge, MD PhD, Min Li, MD, Lichan Xiao, MD, Run Zhang, MD, Jianyong Li, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1300.
https://doi.org/10.1182/blood.V126.23.1300.1300
Published: 2015