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Journal Articles

Conformation-dependent blockage of activated VWF improves outcomes of traumatic brain injury in mice

Xin Xu, Chenyu Wang, Yingang Wu, Katie Houck, Tristan Hilton, Ashley Zhou, Xiaoping Wu, Cha Han, Mengchen Yang, Wei Yang, Fu-Dong Shi, Moritz Stolla, Miguel A. Cruz, Min Li, Jianning Zhang, Jing-fei Dong

Blood (2021) 137 (4): 544–555.

https://doi.org/10.1182/blood.2020007364

Published: 2021

Includes: Supplemental data

Journal Articles

FAM20c-Mediated Serine 1613 Phosphorylation in the A2 Domain of Von Willebrand Factor Regulates ADAMTS13 Activity and Thrombus Formation

Qi Da, PhD, Jennifer Nolasco, B.S., Tanvir Khatlani, PhD, Fernandez Maria, B,S., Miguel A. Cruz, PhD, K. Vinod Vijayan, PhD

Blood (2015) 126 (23): 236.

https://doi.org/10.1182/blood.V126.23.236.236

Published: 2015

Journal Articles

Wdr1-Mediated Actin Reorganization Is Essential for Integrin αIIbβ3 Activation in Platelets

Swapan Kumar Dasgupta, PhD, Qi Da, PhD, Anhquyen Le, Miguel A. Cruz, PhD, Perumal Thiagarajan, MD

Blood (2015) 126 (23): 2231.

https://doi.org/10.1182/blood.V126.23.2231.2231

Published: 2015

Journal Articles

Vimentin Is a Novel Molecule Required for the Formation of Von Willebrand Factor Strings from the Vascular Endothelium

Titilope Ishola, MD PhD, Qi Da, PhD, Sean P Marrelli, PhD, Miguel A. Cruz, PhD

Blood (2015) 126 (23): 2237.

https://doi.org/10.1182/blood.V126.23.2237.2237

Published: 2015

Journal Articles

Intermediate Filament (IF) Protein Vimentin Regulates T Cell Mediated Immune Response in Gvhd

Dan Li, PhD, Patenia Rebecca, BS, Miguel A. Cruz, PhD, Jeffrey J. Molldrem, MD, Richard E. Champlin, MD, Qing Ma, PhD

Blood (2015) 126 (23): 3073.

https://doi.org/10.1182/blood.V126.23.3073.3073

Published: 2015

Journal Articles

Free hemoglobin increases von Willebrand factor–mediated platelet adhesion in vitro: implications for circulatory devices

Qi Da, Miho Teruya, Prasenjit Guchhait, Jun Teruya, John S. Olson, Miguel A. Cruz

Blood (2015) 126 (20): 2338–2341.

https://doi.org/10.1182/blood-2015-05-648030

Published: 2015

Includes: Supplemental data

Journal Articles

Platelet adhesion involves a novel interaction between vimentin and von Willebrand factor under high shear stress

Qi Da, Molly Behymer, Juliana I. Correa, K. Vinod Vijayan, Miguel A. Cruz

Blood (2014) 123 (17): 2715–2721.

https://doi.org/10.1182/blood-2013-10-530428

Published: 2014

Includes: Supplemental data

Journal Articles

Highly electronegative LDL from patients with ST-elevation myocardial infarction triggers platelet activation and aggregation

Hua-Chen Chan, Liang-Yin Ke, Chih-Sheng Chu, An-Sheng Lee, Ming-Yi Shen, Miguel A. Cruz, Jing-Fang Hsu, Kai-Hung Cheng, Hsiu-Chuan Bonnie Chan, Jonathan Lu, Wen-Ter Lai, Tatsuya Sawamura, Sheng-Hsiung Sheu, Jeng-Hsien Yen, Chu-Huang Chen

Blood (2013) 122 (22): 3632–3641.

https://doi.org/10.1182/blood-2013-05-504639

Published: 2013

Includes: Supplemental data

Journal Articles

A Novel Molecular Mechanism In The Interplay Of Platelet GPIb-VWF-Fibrin In Thrombus Formation

Miguel A. Cruz, PhD, Perumal Thiagarajan, MD, Swapan Kumar Dasgupta, Sameer Thacker

Blood (2013) 122 (21): 1065.

https://doi.org/10.1182/blood.V122.21.1065.1065

Published: 2013

Journal Articles

Vimentin Exposed On Platelets Serves As an Adhesive Receptor for Von Willebrand Factor

Miguel A. Cruz, PhD, K. Vinod Vijayan, PhD

Blood (2012) 120 (21): 259.

https://doi.org/10.1182/blood.V120.21.259.259

Published: 2012

Journal Articles

The Study of GPIb-VWF Mediated Early-Stage Platelet Activation Triggering On a Single Cell

Lining Ju, Cheng Zhu, Miguel A. Cruz, PhD, Yunfeng Chen

Blood (2012) 120 (21): 1069.

https://doi.org/10.1182/blood.V120.21.1069.1069

Published: 2012

Journal Articles

Extracellular Hemoglobin Increases the Binding of the Active Form of Von Willebrand Factor to Glycoprotein Ibα and Platelet Activation Under Shear Stress: Implications for Sickle Cell Disease and Other Hemolytic Disorders

Miguel A. Cruz, PhD,, Prasenjit Guchhait, PhD, Ryanne Ashley Brown

Blood (2011) 118 (21): 2095.

https://doi.org/10.1182/blood.V118.21.2095.2095

Published: 2011

Journal Articles

Force-induced cleavage of single VWFA1A2A3 tridomains by ADAMTS-13

Tao Wu, Jiangguo Lin, Miguel A. Cruz, Jing-fei Dong, Cheng Zhu

Blood (2010) 115 (2): 370–378.

https://doi.org/10.1182/blood-2009-03-210369

Published: 2010

Includes: Supplemental data

Journal Articles

Hemoglobin Bound Von Willebrand Factor (HbVWF) Multimers Are Hyperactive and More Prevalent in Patients with Sickle Cell Disease.

Zhou Zhou, PhD, Hyojeong Han, Mark M. Udden, MD, Miguel A. Cruz, PhD, Jing-fei Dong, MD, PhD, Prasenjit Guchhait, PhD

Blood (2009) 114 (22): 3058.

https://doi.org/10.1182/blood.V114.22.3058.3058

Published: 2009

Journal Articles

Identification of Molecular Risk Score in Advanced Hodgkin Lymphoma: Integrating Tumor and Microenvironment Signatures.

Beatriz Sánchez-Espiridión, Carlos Montalbán, Mónica García-Cosio, Jose García-Laraña, Javier Menarguez, Pilar Sabin, Rafael Ramos, José Rodríguez, Francisco Mestre, Miguel Canales, Francisco Javier Alves, Araceli Canovas, Carmen Camarero, Antonio Salar, Sergi Serrano, Angel Castaño, Pedro Sánchez-Godoy, Águeda Bas, Reyes Arranz, Agustín Acevedo, Concepción Rayón, Manuel F. Fresno, Carlos Santonja, Jose Luis López, Manuela Mollejo, Miguel A. Cruz, Hugo Álvarez-Arguelles, Marta LLanos, Carmen Martín, Rafael Martínez, Joaquín González-Carrero, Concepción Poderos, Francisco Mazorra, Eulogio Conde, Teresa Flores, Ramón García-Sanz, Jerónimo Forteza, Máximo Fraga, Jose Luis Bello, María Jose Mestre, Miguel Méndez, Rubén Quibén, Luz Borbolla, Ana Marin-Niebla, Eduardo Ríos, Manuel M. Morente, Miguel A. Piris, Juan F. García

Blood (2009) 114 (22): 3660.

https://doi.org/10.1182/blood.V114.22.3660.3660

Published: 2009

Journal Articles

Soluble Monomeric Von Willebrand Factor A1A2A3 (R1450E) Mutant Fragment Enhances Shear-Induced Platelet Aggregation and Platelet Adhesion to Fibrin(ogen) Via αIIbβ3 Under High Shear Stress.

Miguel A. Cruz, PhD, Katie E. Sowa, Scott M. Smith

Blood (2009) 114 (22): 4025.

https://doi.org/10.1182/blood.V114.22.4025.4025

Published: 2009

Journal Articles

Thermodynamic Analysis of Von Willebrand Disease Type 2B and 2M Mutations on the Structural Stability of the Von Willebrand Factor A1 Domain.

Matthew Auton, BSc, PhD, Erik Sedlák, PhD, Joel L. Moake, MD, Miguel A. Cruz, PhD

Blood (2008) 112 (11): 3389.

https://doi.org/10.1182/blood.V112.11.3389.3389

Published: 2008

Journal Articles

Hemoglobin Blocks Von Willebrand Factor Proteolysis by ADAMTS-13: A Mechanism Associated with Acquired ADAMTS-13 Deficiency in Patients with Sickle Cell Disease

Zhou Zhou, Han Hyojeong, Miguel A. Cruz, PhD, Jose A. Lopez, MD, Jing-fei Dong, MD, PhD, Prasenjit Guchhait, PhD

Blood (2008) 112 (11): 3919.

https://doi.org/10.1182/blood.V112.11.3919.3919

Published: 2008

Journal Articles

Factor H Binds to Von Willebrand Factor (VWF) and Regulates Its Cleavage by ADAMTS-13

Miguel A. Cruz, PhD, Francisca C. Gushiken, MD, Rolando Rumbaut, Kavita N Patel, Nancy Turner, Leticia Nolasco, Hyojeong Han, Matthew Pickering, Jing-fei Dong, MD, PhD, Joel L. Moake, MD, Vahid Afshar-Kharghan, MD

Blood (2008) 112 (11): 3935.

https://doi.org/10.1182/blood.V112.11.3935.3935

Published: 2008

Journal Articles

Single-Molecule Measurements of Force-Induced Cleavage of VWF A1A2A3-Tridomain by ADAMTS13

Tao Wu, Jiangguo Lin, Miguel A. Cruz, PhD, Jing-fei Dong, MD, PhD, Cheng Zhu, PhD

Blood (2008) 112 (11): 3936.

https://doi.org/10.1182/blood.V112.11.3936.3936

Published: 2008

NARROW

Conformation-dependent blockage of activated VWF improves outcomes of traumatic brain injury in mice

FAM20c-Mediated Serine 1613 Phosphorylation in the A2 Domain of Von Willebrand Factor Regulates ADAMTS13 Activity and Thrombus Formation

Wdr1-Mediated Actin Reorganization Is Essential for Integrin αIIbβ3 Activation in Platelets

Vimentin Is a Novel Molecule Required for the Formation of Von Willebrand Factor Strings from the Vascular Endothelium

Intermediate Filament (IF) Protein Vimentin Regulates T Cell Mediated Immune Response in Gvhd

Free hemoglobin increases von Willebrand factor–mediated platelet adhesion in vitro: implications for circulatory devices

Platelet adhesion involves a novel interaction between vimentin and von Willebrand factor under high shear stress

Highly electronegative LDL from patients with ST-elevation myocardial infarction triggers platelet activation and aggregation

A Novel Molecular Mechanism In The Interplay Of Platelet GPIb-VWF-Fibrin In Thrombus Formation

Vimentin Exposed On Platelets Serves As an Adhesive Receptor for Von Willebrand Factor

The Study of GPIb-VWF Mediated Early-Stage Platelet Activation Triggering On a Single Cell

Extracellular Hemoglobin Increases the Binding of the Active Form of Von Willebrand Factor to Glycoprotein Ibα and Platelet Activation Under Shear Stress: Implications for Sickle Cell Disease and Other Hemolytic Disorders

Force-induced cleavage of single VWFA1A2A3 tridomains by ADAMTS-13

Hemoglobin Bound Von Willebrand Factor (HbVWF) Multimers Are Hyperactive and More Prevalent in Patients with Sickle Cell Disease.

Identification of Molecular Risk Score in Advanced Hodgkin Lymphoma: Integrating Tumor and Microenvironment Signatures.

Soluble Monomeric Von Willebrand Factor A1A2A3 (R1450E) Mutant Fragment Enhances Shear-Induced Platelet Aggregation and Platelet Adhesion to Fibrin(ogen) Via αIIbβ3 Under High Shear Stress.

Thermodynamic Analysis of Von Willebrand Disease Type 2B and 2M Mutations on the Structural Stability of the Von Willebrand Factor A1 Domain.

Hemoglobin Blocks Von Willebrand Factor Proteolysis by ADAMTS-13: A Mechanism Associated with Acquired ADAMTS-13 Deficiency in Patients with Sickle Cell Disease

Factor H Binds to Von Willebrand Factor (VWF) and Regulates Its Cleavage by ADAMTS-13

Single-Molecule Measurements of Force-Induced Cleavage of VWF A1A2A3-Tridomain by ADAMTS13

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American Society of Hematology

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American Society of Hematology

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