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Journal Articles

Shear-induced integrin signaling in platelet phosphatidylserine exposure, microvesicle release, and coagulation

Aiming Pang, Yujie Cui, Yunfeng Chen, Ni Cheng, M. Keegan Delaney, Minyi Gu, Aleksandra Stojanovic-Terpo, Cheng Zhu, Xiaoping Du
Journal: Blood
Blood (2018) 132 (5): 533–543.
https://doi.org/10.1182/blood-2017-05-785253
Published: 2018
Includes: Multimedia, Supplemental data
Journal Articles

The integrin PSI domain has an endogenous thiol isomerase function and is a novel target for antiplatelet therapy

Guangheng Zhu, Qing Zhang, Emily C. Reddy, Naadiya Carrim, Yunfeng Chen, Xiaohong Ruby Xu, Miao Xu, Yiming Wang, Yan Hou, Li Ma, Yan Li, Min Rui, Tania N. Petruzziello-Pellegrini, Christopher Lavalle, Tyler W. Stratton, Xi Lei, Reheman Adili, Pingguo Chen, Cheng Zhu, John A. Wilkins, Richard O. Hynes, John Freedman, Heyu Ni
Journal: Blood
Blood (2017) 129 (13): 1840–1854.
https://doi.org/10.1182/blood-2016-07-729400
Published: 2017
Includes: Supplemental data
Journal Articles

Force-Induced Cooperative Unfolding of Two Distinctive Domains in a Single Gpibalpha Molecule

Yunfeng Chen, BS, Lining Ju, PhD, Jizhong Lou, PhD, Cheng Zhu, PhD
Journal: Blood
Blood (2015) 126 (23): 3449.
https://doi.org/10.1182/blood.V126.23.3449.3449
Published: 2015
Journal Articles

Identification and Characterization of Integrin alphaIIbbeta3 Intermediate Affinity State Induced By Gpibalpha Mechanotransduction

Yunfeng Chen, BS, Lining Ju, PhD, Cheng Zhu, PhD
Journal: Blood
Blood (2015) 126 (23): 237.
https://doi.org/10.1182/blood.V126.23.237.237
Published: 2015
Journal Articles

Apolipoprotein Α-IV Is a Novel Ligand of Platelet αIIbβ3 Integrin and an Endogenous Thrombosis Inhibitor: Measurement of Single-Molecular Interactions By Biomembrane Force Probe

Xiaohong Xu, MD, Christopher M. Spring, MSc, Lining Ju, PhD, Yiming Wang, MD, Adili Reheman, MD, Hong Yang, MD, Joseph Wuxun Jin, PhD, Xi Lei, MSc, Yan Yang, MD PhD, Emily C. Reddy, PhD, Yunfeng Chen, PhD, Pingguo Chen, MD PhD, Guangheng Zhu, MD, Patrizia Marchese, PhD, Alessandro Zarpellon, PhD, Hailong Zhang, PhD, YiMin She, PhD, Terry Cyr, PhD, Cheng Zhu, PhD, John Freedman, MD, Patrick Tso, PhD, Sean Davidson, PhD, Zaverio M. Ruggeri, MD, Heyu Ni, MD PhD
Journal: Blood
Blood (2014) 124 (21): 92.
https://doi.org/10.1182/blood.V124.21.92.92
Published: 2014
Journal Articles

Loss of the F-BAR protein CIP4 reduces platelet production by impairing membrane-cytoskeleton remodeling

Yolande Chen, Jorie Aardema, Sayali Kale, Zakary L. Whichard, Arinola Awomolo, Elisabeth Blanchard, Brian Chang, David R. Myers, Lining Ju, Reginald Tran, David Reece, Hilary Christensen, Siham Boukour, Najet Debili, Ted S. Strom, David Rawlings, Francisco X. Vázquez, Gregory A. Voth, Cheng Zhu, Walter H. A. Kahr, Wilbur A. Lam, Seth J. Corey
Journal: Blood
Blood (2013) 122 (10): 1695–1706.
https://doi.org/10.1182/blood-2013-03-484550
Published: 2013
Journal Articles

The Study of GPIb-VWF Mediated Early-Stage Platelet Activation Triggering On a Single Cell

Lining Ju, Cheng Zhu, Miguel A. Cruz, PhD, Yunfeng Chen
Journal: Blood
Blood (2012) 120 (21): 1069.
https://doi.org/10.1182/blood.V120.21.1069.1069
Published: 2012
Journal Articles

Force-induced cleavage of single VWFA1A2A3 tridomains by ADAMTS-13

Tao Wu, Jiangguo Lin, Miguel A. Cruz, Jing-fei Dong, Cheng Zhu
Journal: Blood
Blood (2010) 115 (2): 370–378.
https://doi.org/10.1182/blood-2009-03-210369
Published: 2010
Includes: Supplemental data
Journal Articles

Single-Molecule Measurements of Force-Induced Cleavage of VWF A1A2A3-Tridomain by ADAMTS13

Tao Wu, Jiangguo Lin, Miguel A. Cruz, PhD, Jing-fei Dong, MD, PhD, Cheng Zhu, PhD
Journal: Blood
Blood (2008) 112 (11): 3936.
https://doi.org/10.1182/blood.V112.11.3936.3936
Published: 2008
Journal Articles

Sliding-Rebinding Mechanism Governs Glycoprotein Ib/von Willebrand Factor Catch Bonds.

Jizhong Lou, PhD, Cheng Zhu, Ph.D.
Journal: Blood
Blood (2007) 110 (11): 3723.
https://doi.org/10.1182/blood.V110.11.3723.3723
Published: 2007
Journal Articles

Glycoprotein Ibα Forms Catch Bonds with von Willebrand Factor A1 Domain but Not with Mutant A1 Domains Exhibiting Properties of Type 2B von Willebrand Disease.

Tao Wu, Tadayuki Yago, Jun Yang, Jonathan Miner, Leslie Coburn, Jose A. Lopez, Miguel A. Cruz, Larry V. McIntire, Rodger P. McEver, Cheng Zhu
Journal: Blood
Blood (2007) 110 (11): 293.
https://doi.org/10.1182/blood.V110.11.293.293
Published: 2007
Journal Articles

Cell-specific, activation-dependent regulation of neutrophil CD32A ligand-binding function

Shanmugam Nagarajan, Kala Venkiteswaran, Michael Anderson, Umar Sayed, Cheng Zhu, Periasamy Selvaraj
Journal: Blood
Blood (2000) 95 (3): 1069–1077.
https://doi.org/10.1182/blood.V95.3.1069.003k14_1069_1077
Published: 2000