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Journal Articles

Disruption of dNTP homeostasis by ribonucleotide reductase hyperactivation overcomes AML differentiation blockade

Hanying Wang, Xin He, Lei Zhang, Haojie Dong, Feiteng Huang, Jie Xian, Min Li, Wei Chen, Xiyuan Lu, Khyatiben V. Pathak, Wenfeng Huang, Zheng Li, Lianjun Zhang, Le Xuan Truong Nguyen, Lu Yang, Lifeng Feng, David J. Gordon, Jing Zhang, Patrick Pirrotte, Chun-Wei Chen, Amandeep Salhotra, Ya-Huei Kuo, David Horne, Guido Marcucci, David B. Sykes, Stefano Tiziani, Hongchuan Jin, Xian Wang, Ling Li
Journal: Blood
Blood (2022) 139 (26): 3752–3770.
https://doi.org/10.1182/blood.2021015108
Published: 2022
Includes: Supplemental data
Journal Articles

Repurposing Nelarabine to Induce Differentiation of Acute Myeloid Leukemia

Hanying Wang, Xin He, MD, Feiteng Huang, MS, Haojie Dong, PhD, Wei Chen, PhD, Zheng Li, MS, Jie Sun, PhD, Yinghui Zhu, PhD, Lei Zhang, MD, Yuhui Wu, MD, Lifeng Feng, PhD, Jing Zhang, PhD, Samer Khaled, MD, Guido Marcucci, MD, David Sykes, MD PhD, Hongchuan Jin, MD PhD, Xian Wang, MD PhD, Ling Li, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26.
https://doi.org/10.1182/blood-2020-139922
Published: 2020
Journal Articles

Activation of SIRT1 Deacetylase As a Therapeutic Approach for Myelodysplastic Syndromes By Restoring TET2 Function

Jie Sun, PhD, Yinghui Zhu, PhD, Xin He, MD, Zonghui Ding, PhD, Haojie DONG, PhD, Yimei Feng, MD PhD, Xiaochun Yu, MD PhD, Dandan Zhao, MD, Herman Wu, BS, Lifeng Feng, PhD, Kaoru Tohyama, MD, Hongchuan Jin, MD PhD, Philipp Oberdoerffer, PhD, Yang Jo Chung, PhD, Peter D. Aplan, MD, Bin Zhang, PhD, Ya-Huei Kuo, PhD, Ravi Bhatia, MD, Andrea Pellagatti, PhD, Jacqueline Boultwood, PhD, Nadia Carlesso, MD PhD, Guido Marcucci, MD, Ling Li, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2497.
https://doi.org/10.1182/blood.V130.Suppl_1.2497.2497
Published: 2017
Journal Articles

TET2 Activity Is Modulated By SIRT1-Mediated Protein Deacetylation: A Potential Therapeutic Target in Myelodysplastic Syndrome

Jie Sun, MS, Yinghui Zhu, PhD, Zonghui Ding, PhD, Haojie Dong, PhD, Yimei Feng, PhD MD, Qiang Chen, PhD, Xiaochun Yu, PhD MD, Dandan Zhao, MD, Herman Wu, BS, Lifeng Feng, PhD, Kaoru Tohyama, MD PhD, Philipp Oberdoerffer, PhD, Bin Zhang, PhD, Ya-Huei Kuo, PhD, Ravi Bhatia, MD, Hongchuan Jin, PhD MD, Guido Marcucci, MD, Ling Li, PhD
Journal: Blood
Blood (2016) 128 (22): 1053.
https://doi.org/10.1182/blood.V128.22.1053.1053
Published: 2016