1-4 of 4
David Horne
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Disruption of dNTP homeostasis by ribonucleotide reductase hyperactivation overcomes AML differentiation blockade

Hanying Wang, Xin He, Lei Zhang, Haojie Dong, Feiteng Huang, Jie Xian, Min Li, Wei Chen, Xiyuan Lu, Khyatiben V. Pathak, Wenfeng Huang, Zheng Li, Lianjun Zhang, Le Xuan Truong Nguyen, Lu Yang, Lifeng Feng, David J. Gordon, Jing Zhang, Patrick Pirrotte, Chun-Wei Chen, Amandeep Salhotra, Ya-Huei Kuo, David Horne, Guido Marcucci, David B. Sykes, Stefano Tiziani, Hongchuan Jin, Xian Wang, Ling Li
Journal: Blood
Blood (2022) 139 (26): 3752–3770.
https://doi.org/10.1182/blood.2021015108
Published: 2022
Includes: Supplemental data
Journal Articles

Antileukemic Activity of 8-Chloro-Adenosine (8-Cl-Ado) Is Mediated By Mir-155 Degradation and ErbB3 Binding Protein (Ebp1)-Dependent p53 Activation: A Novel Therapeutic Approach for FLT3-ITD Acute Myeloid Leukemia (AML)

Ralf Buettner, PhD, Le Xuan Truong Nguyen, PhD, Bijender Kumar, PhD, Corey James Morales, BA, BS, Chao Liu, PhD, Lisa S Chen, PhD, Tea Pemovska, PhD, Ryan Thompson, BS, Ling Li, PhD, Dinh Hoa Hoang, BS, Bin Zhang, PhD, Lucy Ghoda, PhD, Claudia Kowolik, PhD, Mika Kontro, MD, Krister Wennerberg, PhD, Calum Leitch, PhD, Xiaochun Yu, MD PhD, Ching-Cheng Chen, PhD, David Horne, PhD, Varsha Gandhi, PhD, Vinod A. Pullarkat, MD, Guido Marcucci, Steven T Rosen
Journal: Blood
Blood (2018) 132 (Supplement 1): 3938.
https://doi.org/10.1182/blood-2018-99-119880
Published: 2018
Journal Articles

8-Chloro-Adenosine Inhibits Molecular Poor-Risk Acute Myeloid Leukemia (AML) and Leukemic Stem Cells (LSC) Growth and Synergizes with the BCL-2 Inhibitor Venetoclax (ABT-199)

Ralf Buettner, PhD, Ching-Cheng Chen, PhD, Bijender Kumar, PhD, Corey Morales, BA, BS, Lisa S Chen, PhD, Krister Wennerberg, PhD, Ryan Thompson, MS, Tea Pemovska, MSc, Ling Li, PhD, Bin Zhang, PhD, Claudia Kowolik, PhD, Mika Kontro, MD, Calum Leitch, MD, David Horne, PhD, Joycelynne Palmer, PhD, Varsha Gandhi, PhD, Guido Marcucci, MD, Vinod Pullarkat, MD, Steven T. Rosen, MD
Journal: Blood
Blood (2016) 128 (22): 2758.
https://doi.org/10.1182/blood.V128.22.2758.2758
Published: 2016
Journal Articles

Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis

Hongfeng Yuan, Zhiqiang Wang, Ling Li, Hao Zhang, Hardik Modi, David Horne, Ravi Bhatia, WenYong Chen
Journal: Blood
Blood (2012) 119 (8): 1904–1914.
https://doi.org/10.1182/blood-2011-06-361691
Published: 2012
Includes: Supplemental data