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    Journal Articles

    Disruption of dNTP homeostasis by ribonucleotide reductase hyperactivation overcomes AML differentiation blockade

    Hanying Wang, Xin He, Lei Zhang, Haojie Dong, Feiteng Huang, Jie Xian, Min Li, Wei Chen, Xiyuan Lu, Khyatiben V. Pathak, Wenfeng Huang, Zheng Li, Lianjun Zhang, Le Xuan Truong Nguyen, Lu Yang, Lifeng Feng, David J. Gordon, Jing Zhang, Patrick Pirrotte, Chun-Wei Chen, Amandeep Salhotra, Ya-Huei Kuo, David Horne, Guido Marcucci, David B. Sykes, Stefano Tiziani, Hongchuan Jin, Xian Wang, Ling Li
    Journal: Blood
    Blood (2022) 139 (26): 3752–3770.
    https://doi.org/10.1182/blood.2021015108
    Published: 2022
    Includes: Supplemental data
    Journal Articles

    The Combined Treatment with the FLT3-Inhibitor AC220 and the Complex I Inhibitor Iacs-010759 Synergistically Depletes Wt- and FLT3-Mutated Acute Myeloid Leukemia Cells

    Xiyuan Lu, Alessia Lodi, PhD, Lina Han, PhD, Joseph R Marszalek, PhD, Marina Konopleva, MD PhD, Stefano Tiziani, PhD
    Journal: Blood
    Blood (2020) 136 (Supplement 1): 5–6.
    https://doi.org/10.1182/blood-2020-141986
    Published: 2020

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