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Journal Articles

MyD88L265P Mutation Impairs Bone Marrow Hematopoietic Stem Cell Function in a Cell-Autonomous Way Resulting in an MPN-like Phenotype

Greta Zara, Sonia Rodriguez-Rodriguez, Nadia Carlesso

Blood (2024) 144 (Supplement 1): 2653.

https://doi.org/10.1182/blood-2024-201808

Published: 2024

Journal Articles

Homoharringtonine inhibits the NOTCH/MYC pathway and exhibits antitumor effects in T-cell acute lymphoblastic leukemia

Shanshan Suo, Dandan Zhao, Fenglin Li, Yi Zhang, Sonia Rodriguez-Rodriguez, Le Xuan Truong Nguyen, Lucy Ghoda, Nadia Carlesso, Guido Marcucci, Bin Zhang, Jie Jin

Blood (2024) 144 (12): 1343–1347.

https://doi.org/10.1182/blood.2023023400

Published: 2024

Includes: Supplemental data

Journal Articles

Acute Inflammation Redirect Bone Marrow Hematopoietic Stem Cell Cycling and Differentiation Program By Reshaping Their Chromatin Architecture at Long-Term

Greta Zara, Amy Leung, Hiroyuki Kato, Dustin Schones, Young-Woong Kim, Sonia Rodriguez-Rodriguez, Huajia Zhang, Zhaohui Gu, Nadia Carlesso

Blood (2023) 142 (Supplement 1): 1300.

https://doi.org/10.1182/blood-2023-186567

Published: 2023

Journal Articles

Homoharringtonine Exhibits Anti-Tumor Effect in T-Cell Acute Lymphoblastic Leukemia By Targeting Notch1/Myc Pathway

Shanshan Suo, Dandan Zhao, Fenglin Li, Sonia Rodriguez, Junjing Qiao, Chen Liang, Le Xuan Truong Nguyen, Dinh Hoa Hoang, Fang Chen, Ivan Rodriguez, Lucy Ghoda, Tinisha McDonald, Ling Li, Nadia Carlesso, Bin Zhang, Guido Marcucci, Jie Jin

Blood (2022) 140 (Supplement 1): 362–363.

https://doi.org/10.1182/blood-2022-169679

Published: 2022

Journal Articles

Myeloid-Biased HSC Require Semaphorin4a from the Bone Marrow Niche for Self-Renewal Under Stress and Life-Long Persistence

Blood (2021) 138 (Supplement 1): 3283.

https://doi.org/10.1182/blood-2021-153831

Published: 2021

Journal Articles

Targeting the bone marrow niche in hemoglobinopathies

Nadia Carlesso

Blood (2020) 136 (5): 529–531.

https://doi.org/10.1182/blood.2020006305

Published: 2020

Journal Articles

Spred1 Insufficiency in the Hematopoietic and/or Vascular Compartments of the Bone Marrow (BM) Niche Promotes Aggressive Leukemogenesis in Chronic Myelogenous Leukemia (CML)

Junjing Qiao, MD PhD, Dandan Zhao, MD, Le Xuan Truong Nguyen, PhD, Herman Wu, BS, Gang Liu, PhD, Shanshan Suo, MD, Huafeng Wang, Yasmin Elhajmoussa, Chen Liang, MD, David Snyder, MD, Haris Ali, MD, Steven Rosen, MD, Nadia Carlesso, MD, Ling Li, PhD, Ya-Huei Kuo, PhD, Guido Marcucci, MD, Bin Zhang, PhD

Blood (2019) 134 (Supplement_1): 3791.

https://doi.org/10.1182/blood-2019-127616

Published: 2019

Journal Articles

FLT3-ITD Activates Cytoplasmic Drosha-Dependent Non-Canonical Mechanisms of Mir-155 Biogenesis in Acute Myeloid Leukemia

Le Xuan Truong Nguyen, PhD, Bin Zhang, PhD, Dinh Hoa Hoang, BS, Dandan Zhao, MD, Sergio Branciamore, Davide Maestrini, PhD, Yu-Lin SU, PhD, Sonia Rodriguez, PhD, Flavia Pichiorri, PhD, Steven Rosen, MD, Michael A. Caligiuri, MD, Stephen J. Forman, MD, Ling Li, PhD, Marcin Kortylewski, PhD, Russell Rockne, PhD, Ya-Huei Kuo, PhD, Nadia Carlesso, MD, Guido Marcucci, MD

Blood (2019) 134 (Supplement_1): 2722.

https://doi.org/10.1182/blood-2019-131871

Published: 2019

Journal Articles

Targeting MiR-126 Blocks Progression of Myelodysplastic Syndrome and Transformation into Acute Myeloid Leukemia

Huafeng Wang, MD, Jie Sun, PhD, Dandan Zhao, MD, Hongyan Tong, Herman Wu, BS, Xia Li, PhD, Yingwan Luo, MD, Dan Dong, PhD, Tinisha McDonald, MS, Anthony Stein, MD, Monzr M. Al Malki, MD, Flavia Pichiorri, PhD, Nadia Carlesso, MD, Ya-Huei Kuo, PhD, Bin Zhang, PhD, Guido Marcucci, MD, Ling Li, PhD, Jie Jin, MD PhD

Blood (2019) 134 (Supplement_1): 1707.

https://doi.org/10.1182/blood-2019-130375

Published: 2019

Journal Articles

Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL -rearranged acute lymphoblastic leukemia

Blood (2019) 134 (15): 1257–1268.

https://doi.org/10.1182/blood.2019002457

Published: 2019

Includes: Supplemental data

Journal Articles

Inhibition of PRMT1 Mediated FLT3 Arginine Methylation As a Potent Therapeutic Strategy for MLL-r ALL

Yinghui Zhu, PhD, Xin He, PhD, Haojie Dong, PhD, Jie Sun, PhD, Hanying Wang, PhD, Lei Zhang, PhD, Yunan Miao, PhD, Jian Jin, PhD, Yudao Shen, PhD, Jianjun Chen, PhD, Markus Muschen, MD, Chun-Wei Chen, PhD, Marina Y. Konopleva, MD PhD, Weili Sun, MD PhD, Bin Zhang, PhD, Ya-Huei Kuo, PhD, Nadia Carlesso, MD PhD, Guido Marcucci, Ling Li, PhD

Blood (2018) 132 (Supplement 1): 892.

https://doi.org/10.1182/blood-2018-99-115139

Published: 2018

Journal Articles

PRMT1 Mediated FLT3 Methylation As a Therapeutic Vulnerability in FLT3-ITD + AML

Blood (2018) 132 (Supplement 1): 760.

https://doi.org/10.1182/blood-2018-99-112766

Published: 2018

Journal Articles

Rap1 Gtpases Regulate the Retention and Engraftment of Hematopoietic Stem and Progenitor Cells

Baskar Ramdas, PhD, Joydeep Ghosh, PhD, Raghuveer Singh Mali, PhD, Zollman Amy, Nadia Carlesso, MD PhD, Malgorzata Kamocka M, Dunn W Kenneth, PhD, Lawrance Quilliam, PhD, Reuben Kapur, PhD

Blood (2018) 132 (Supplement 1): 326.

https://doi.org/10.1182/blood-2018-99-117197

Published: 2018

Journal Articles

Downregulation of Mir-142 Promotes Leukemia Growth in Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL): A Possible Novel Therapeutic Target?

Blood (2018) 132 (Supplement 1): 1338.

https://doi.org/10.1182/blood-2018-99-119599

Published: 2018

Journal Articles

Copper 64–labeled daratumumab as a PET/CT imaging tracer for multiple myeloma

Blood (2018) 131 (7): 741–745.

https://doi.org/10.1182/blood-2017-09-807263

Published: 2018

Includes: Multimedia, Supplemental data

Journal Articles

Defective Notch Activation in Mesenchymal Cells Contributes to Myeloproliferative Neoplasm in Aged Mice

Young-Woong Kim, PhD, Sonia Rodriguez, PhD, Lin Wang, PhD, Guido Marcucci, MD, Amy Zollman, Nadia Carlesso, MD PhD

Blood (2017) 130 (Supplement 1): 134.

https://doi.org/10.1182/blood.V130.Suppl_1.134.134

Published: 2017

Journal Articles

Anti-IL1RAP/CD3 Bispecific Antibody (BsAb) Is a Promising Novel and Effective Therapy for Acute Myeloid Leukemia (AML)

Blood (2017) 130 (Supplement 1): 1361.

https://doi.org/10.1182/blood.V130.Suppl_1.1361.1361

Published: 2017

Journal Articles

MiR- 16 Regulates Crosstalk in NF-κB Inflammatory Signaling between Myeloma Cells and Bone Marrow Macrophages

Jihane Khalife, Domenico Viola, BS, Jayeeta Ghose, Robert Weingart, James F Sanchez, Craig C Hofmeister, MDMPH, Amrita Krishnan, MD, Guido Marcucci, MD, Nadia Carlesso, MD PhD, Enrico Caserta, PhD, Flavia Pichiorri, PhD

Blood (2017) 130 (Supplement 1): 4351.

https://doi.org/10.1182/blood.V130.Suppl_1.4351.4351

Published: 2017

Journal Articles

Activation of SIRT1 Deacetylase As a Therapeutic Approach for Myelodysplastic Syndromes By Restoring TET2 Function

Blood (2017) 130 (Supplement 1): 2497.

https://doi.org/10.1182/blood.V130.Suppl_1.2497.2497

Published: 2017

Journal Articles

Reacting to Inflammatory Signals

Nadia Carlesso, MD PhD

Blood (2015) 126 (23): SCI-30.

https://doi.org/10.1182/blood.V126.23.SCI-30.SCI-30

Published: 2015

NARROW

MyD88L265P Mutation Impairs Bone Marrow Hematopoietic Stem Cell Function in a Cell-Autonomous Way Resulting in an MPN-like Phenotype

Homoharringtonine inhibits the NOTCH/MYC pathway and exhibits antitumor effects in T-cell acute lymphoblastic leukemia

Acute Inflammation Redirect Bone Marrow Hematopoietic Stem Cell Cycling and Differentiation Program By Reshaping Their Chromatin Architecture at Long-Term

Homoharringtonine Exhibits Anti-Tumor Effect in T-Cell Acute Lymphoblastic Leukemia By Targeting Notch1/Myc Pathway

Myeloid-Biased HSC Require Semaphorin4a from the Bone Marrow Niche for Self-Renewal Under Stress and Life-Long Persistence

Targeting the bone marrow niche in hemoglobinopathies

Spred1 Insufficiency in the Hematopoietic and/or Vascular Compartments of the Bone Marrow (BM) Niche Promotes Aggressive Leukemogenesis in Chronic Myelogenous Leukemia (CML)

FLT3-ITD Activates Cytoplasmic Drosha-Dependent Non-Canonical Mechanisms of Mir-155 Biogenesis in Acute Myeloid Leukemia

Targeting MiR-126 Blocks Progression of Myelodysplastic Syndrome and Transformation into Acute Myeloid Leukemia

Targeting PRMT1-mediated FLT3 methylation disrupts maintenance of MLL -rearranged acute lymphoblastic leukemia

Inhibition of PRMT1 Mediated FLT3 Arginine Methylation As a Potent Therapeutic Strategy for MLL-r ALL

PRMT1 Mediated FLT3 Methylation As a Therapeutic Vulnerability in FLT3-ITD + AML

Rap1 Gtpases Regulate the Retention and Engraftment of Hematopoietic Stem and Progenitor Cells

Downregulation of Mir-142 Promotes Leukemia Growth in Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL): A Possible Novel Therapeutic Target?

Copper 64–labeled daratumumab as a PET/CT imaging tracer for multiple myeloma

Defective Notch Activation in Mesenchymal Cells Contributes to Myeloproliferative Neoplasm in Aged Mice

Anti-IL1RAP/CD3 Bispecific Antibody (BsAb) Is a Promising Novel and Effective Therapy for Acute Myeloid Leukemia (AML)

MiR- 16 Regulates Crosstalk in NF-κB Inflammatory Signaling between Myeloma Cells and Bone Marrow Macrophages

Activation of SIRT1 Deacetylase As a Therapeutic Approach for Myelodysplastic Syndromes By Restoring TET2 Function

Reacting to Inflammatory Signals

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American Society of Hematology

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