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Journal Articles

Anti-IL1RAP/CD3 Bispecific Antibody (BsAb) Is a Promising Novel and Effective Therapy for Acute Myeloid Leukemia (AML)

Blood (2017) 130 (Supplement 1): 1361.

https://doi.org/10.1182/blood.V130.Suppl_1.1361.1361

Published: 2017

Journal Articles

PNC ¯ 27 Targeting Plasma Membrane HDM2: A Potentially Novel Therapeutic Approach for Acute Myeloid Leukemia (AML)

Huafeng Wang, Bin Zhang, PhD, Dandan Zhao, MD, Estelle Troadec, PhD, Weixu Meng, PhD MD, Allen Lin, Anthony S. Stein, MD, Monzr M. Al Malki, MD, Herman Wu, BS, Tinisha Mcdonald, Jie Jin, Guido Marcucci, MD

Blood (2017) 130 (Supplement 1): 2518.

https://doi.org/10.1182/blood.V130.Suppl_1.2518.2518

Published: 2017

Journal Articles

Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor–treated CML stem cells

Bin Zhang, Su Chu, Puneet Agarwal, Victoria L. Campbell, Lisa Hopcroft, Heather G. Jørgensen, Allen Lin, Karl Gaal, Tessa L. Holyoake, Ravi Bhatia

Blood (2016) 128 (23): 2671–2682.

https://doi.org/10.1182/blood-2015-11-679928

Published: 2016

Journal Articles

Knockdown (KD) of Mir-126 Expression Enhances Tyrosine Kinase Inhibitor (TKI)-Mediated Targeting of Chronic Myelogenous Leukemia (CML) Stem Cells

Bin Zhang, PhD, Ling Li, PhD, Ching-Cheng Chen, PhD, Anthony S. Stein, MD, Haris Ali, MD, David S. Snyder, MD, Allen Lin, Adrienne Dorrance, PhD, Piotr Swiderski, PhD, Ravi Bhatia, MD, Danilo Perrotti, MD PhD, Stephen J. Forman, MD, Ya-Huei Kuo, PhD, Marcin Kortylewski, PhD, Guido Marcucci, MD

Blood (2015) 126 (23): 51.

https://doi.org/10.1182/blood.V126.23.51.51

Published: 2015

Journal Articles

Proteomics Profiling of Leukemia Derived Exosomes: A Potential Role in Leukemic Transformation

Bijender Kumar, PhD, Lei Zhang, PhD, Yunan Miao, Gerald Wuenschell, Allen Lin, Vinod Pullarkat, MD, Guido Marcucci, MD, Robert Hickey, PhD, Ching-Cheng Chen, PhD

Blood (2015) 126 (23): 3857.

https://doi.org/10.1182/blood.V126.23.3857.3857

Published: 2015

Journal Articles

Combination of Dasatinib with Conventional Chemotherapy Is Associated with a High Response Rate in High Risk Acute Myeloid Leukemia (AML)

Blood (2015) 126 (23): 3743.

https://doi.org/10.1182/blood.V126.23.3743.3743

Published: 2015

Journal Articles

Inhibition of HDAC8 Reactivates p53 and Abrogates Leukemia Stem Cell Activity in CBFβ-SMMHC Associated Acute Myeloid Leukemia

Jing Qi, PhD, Qi Cai, PhD, Sandeep Singh, Ling Li, PhD, Hongjun Liu, Tinisha McDonald, B.S., Allen Lin, Ravi Bhatia, MD, wei-Jan Huang, PhD, chung-I Chang, ya-Huei Kuo, PhD

Blood (2014) 124 (21): 363.

https://doi.org/10.1182/blood.V124.21.363.363

Published: 2014

Journal Articles

Role of Enhanced Microenvironmental Interleukin-1 (IL-1) Expression and Increased IL-1 Responsiveness in Persistence of Leukemia Stem Cells in TKI Treated CML Patients

Bin Zhang, PhD, YinWei Ho, Tinisha McDonald, B.S., Allen Lin, David S Snyder, MD, Vu N. Ngo, PhD, Tessa L. Holyoake, MD PhD, Ravi Bhatia, MD

Blood (2014) 124 (21): 4357.

https://doi.org/10.1182/blood.V124.21.4357.4357

Published: 2014

Journal Articles

Role of altered growth factor receptor-mediated JAK2 signaling in growth and maintenance of human acute myeloid leukemia stem cells

Amy M. Cook, Liang Li, Yinwei Ho, Allen Lin, Ling Li, Anthony Stein, Stephen Forman, Danilo Perrotti, Richard Jove, Ravi Bhatia

Blood (2014) 123 (18): 2826–2837.

https://doi.org/10.1182/blood-2013-05-505735

Published: 2014

Includes: Supplemental data

Journal Articles

Pharmacological Inhibition Of The SIRT1 Deacetylase With The Small Molecule Inhibitor Tenovin-6 Enhances Ablation Of FLT3-ITD+ LSC In Combination With TKI Treatment

Ling Li, PhD, Tereza Osdal, MSc, YinWei Ho, MA, Tinisha McDonald, Sookhee Chun, Su Chu, MD, Allen Lin, Cedric Dos Santos, Ph.D, Mihaela Lucia Popa, VMD, Bjorn T Gjertsen, MD PhD, Wenyong Chen, PhD, Sonia Lain, Emmet McCormack, PhD, Ravi Bhatia, MD

Blood (2013) 122 (21): 2685.

https://doi.org/10.1182/blood.V122.21.2685.2685

Published: 2013

Journal Articles

Selective Anti Leukemic Activity Of Low Dose Decitabine In Combination With Ruxolitinib Against Stem/Progenitor Cells From Elderly AML Patients

Cedric Dos Santos, Ph.D, Puneet Agarwal, McDonald Tinisha, Allen Lin, Stephen J. Forman, MD, Ya-Huei Kuo, PhD, Ravi Bhatia, MD

Blood (2013) 122 (21): 2690.

https://doi.org/10.1182/blood.V122.21.2690.2690

Published: 2013

Journal Articles

Selective Targeting Of Inv(16)+ AML Stem Progenitor Cells By Inhibiting HDAC8

Jing Qi, PhD, Sandeep Singh, Qi Cai, PhD, Ling Li, PhD, Hongjun Liu, Hieu Vu, wei-Jan Huang, PhD, Tinisha McDonald, Allen Lin, chung-I Chang, Ravi Bhatia, MD, Ya-Huei Kuo, PhD

Blood (2013) 122 (21): 224.

https://doi.org/10.1182/blood.V122.21.224.224

Published: 2013

Journal Articles

The Src and c-Kit kinase inhibitor dasatinib enhances p53-mediated targeting of human acute myeloid leukemia stem cells by chemotherapeutic agents

Cedric Dos Santos, Tinisha McDonald, Yin Wei Ho, Hongjun Liu, Allen Lin, Stephen J. Forman, Ya-Huei Kuo, Ravi Bhatia

Blood (2013) 122 (11): 1900–1913.

https://doi.org/10.1182/blood-2012-11-466425

Published: 2013

Includes: Supplemental data

Journal Articles

Dasatinib Enhances Targeting of Human AML Leukemia Stem Cells by Chemotherapeutic Agents Via Activation of p53

Cedric Dos Santos, Ph.D, Tinisha McDonald, YinWei Ho, Liu Hongjun, Allen Lin, Stephen J Forman, MD, Kuo Ya-Huei, Ph.D, Ravi Bhatia, MD

Blood (2012) 120 (21): 3590.

https://doi.org/10.1182/blood.V120.21.3590.3590

Published: 2012

Journal Articles

Src Kinase Inhibition by Dasatinib Enhances Targeting of Human AML Stem/Progenitor Cells by Chemotherapeutic Agents

Cedric Emmanuel Dos Santos, PhD, Ling Li, PhD, Tinisha McDonald, B.S., Liang Li, PhD, Allen Lin, Ya-Huei Kuo, PhD, Ravi Bhatia, MD

Blood (2011) 118 (21): 4270.

https://doi.org/10.1182/blood.V118.21.4270.4270

Published: 2011

Journal Articles

Persistence of leukemia stem cells in chronic myelogenous leukemia patients in prolonged remission with imatinib treatment

Su Chu, Tinisha McDonald, Allen Lin, Sujata Chakraborty, Qin Huang, David S. Snyder, Ravi Bhatia

Blood (2011) 118 (20): 5565–5572.

https://doi.org/10.1182/blood-2010-12-327437

Published: 2011

Includes: Supplemental data

Journal Articles

Dose Dependent Effect of Deferasirox on Hematopoietic Progeneitors of Myelodysplastic Syndrome

Vinod Pullarkat, Arjun Sehgal, Liang Li, MD, PhD, Allen Lin, Stephen J. Forman, M.D., Ravi Bhatia, MD

Blood (2010) 116 (21): 3994.

https://doi.org/10.1182/blood.V116.21.3994.3994

Published: 2010

Journal Articles

Validation of the Cord Blood (CB) APGAR Score System to Predict Neutrophil Engraftment of Plasma Depleted CB Products

Robert Chow, M.D., B.C. Wang, M.S., Dennis Chou, Allen Lin, Judy Kang, Michelle Chow, Lawrence D. Petz, MD, Joanne Kurtzberg, MD

Blood (2010) 116 (21): 3549.

https://doi.org/10.1182/blood.V116.21.3549.3549

Published: 2010

Journal Articles

SFK Inhibition with Dasatinib Results In Selective Targeting of Primitive Human Acute Myeloid Leukemia Stem and Progenitor Cells.

Cedric Emmanuel Dos Santos, PhD, Tinisha McDonald, BS, Liang Li, MD, PhD, Allen Lin, Ya-Huei Kuo, PhD, Ravi Bhatia, MD

Blood (2010) 116 (21): 1053.

https://doi.org/10.1182/blood.V116.21.1053.1053

Published: 2010

Journal Articles

A Phase I Study of the HDAC Inhibitor LBH589 in Combination with Imatinib for Patients with CML in Cytogenetic Remission with Residual Disease Detectable by Q-PCR.

Ravi Bhatia, David S. Snyder, Allen Lin, Jennifer Arceo, Linda Seymour, Michael Deininger, Jerald Radich, Suzette Blanchard, Stephen Forman

Blood (2009) 114 (22): 2194.

https://doi.org/10.1182/blood.V114.22.2194.2194

Published: 2009

NARROW

Anti-IL1RAP/CD3 Bispecific Antibody (BsAb) Is a Promising Novel and Effective Therapy for Acute Myeloid Leukemia (AML)

PNC ¯ 27 Targeting Plasma Membrane HDM2: A Potentially Novel Therapeutic Approach for Acute Myeloid Leukemia (AML)

Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor–treated CML stem cells

Knockdown (KD) of Mir-126 Expression Enhances Tyrosine Kinase Inhibitor (TKI)-Mediated Targeting of Chronic Myelogenous Leukemia (CML) Stem Cells

Proteomics Profiling of Leukemia Derived Exosomes: A Potential Role in Leukemic Transformation

Combination of Dasatinib with Conventional Chemotherapy Is Associated with a High Response Rate in High Risk Acute Myeloid Leukemia (AML)

Inhibition of HDAC8 Reactivates p53 and Abrogates Leukemia Stem Cell Activity in CBFβ-SMMHC Associated Acute Myeloid Leukemia

Role of Enhanced Microenvironmental Interleukin-1 (IL-1) Expression and Increased IL-1 Responsiveness in Persistence of Leukemia Stem Cells in TKI Treated CML Patients

Role of altered growth factor receptor-mediated JAK2 signaling in growth and maintenance of human acute myeloid leukemia stem cells

Pharmacological Inhibition Of The SIRT1 Deacetylase With The Small Molecule Inhibitor Tenovin-6 Enhances Ablation Of FLT3-ITD+ LSC In Combination With TKI Treatment

Selective Anti Leukemic Activity Of Low Dose Decitabine In Combination With Ruxolitinib Against Stem/Progenitor Cells From Elderly AML Patients

Selective Targeting Of Inv(16)+ AML Stem Progenitor Cells By Inhibiting HDAC8

The Src and c-Kit kinase inhibitor dasatinib enhances p53-mediated targeting of human acute myeloid leukemia stem cells by chemotherapeutic agents

Dasatinib Enhances Targeting of Human AML Leukemia Stem Cells by Chemotherapeutic Agents Via Activation of p53

Src Kinase Inhibition by Dasatinib Enhances Targeting of Human AML Stem/Progenitor Cells by Chemotherapeutic Agents

Persistence of leukemia stem cells in chronic myelogenous leukemia patients in prolonged remission with imatinib treatment

Dose Dependent Effect of Deferasirox on Hematopoietic Progeneitors of Myelodysplastic Syndrome

Validation of the Cord Blood (CB) APGAR Score System to Predict Neutrophil Engraftment of Plasma Depleted CB Products

SFK Inhibition with Dasatinib Results In Selective Targeting of Primitive Human Acute Myeloid Leukemia Stem and Progenitor Cells.

A Phase I Study of the HDAC Inhibitor LBH589 in Combination with Imatinib for Patients with CML in Cytogenetic Remission with Residual Disease Detectable by Q-PCR.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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