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Journal Articles

Using Single Cell Multi-Omic Clonal Tracking in SMM to Identify Clones That Progress to MM and Harbor Treatment Resistance Features

Adam Sciambi, Daniel Mendoza, Indira Krishnan, Joanne Nguyen, Lubna Nousheen, Benjamin Geller, Cedric Dos Santos, Vivek S. Chopra, Habib Hamidi, Michael Nixon, Yann Nouet, Todd E. Druley, Herve Avet-Loiseau

Blood (2024) 144 (Supplement 1): 4722.

https://doi.org/10.1182/blood-2024-205533

Published: 2024

Journal Articles

Integrative Analysis of the Tumor and Microenvironment to Model the Molecular Heterogeneity Underlying the Response to Cevostamab in Relapsed/Refractory Multiple Myeloma

Habib Hamidi, Rin Nakamura, Sumi Roy, Kamalakannan Rajasekaran, Giovanni Diaz, Cedric Dos Santos, Teiko Sumiyoshi

Blood (2023) 142 (Supplement 1): 3305.

https://doi.org/10.1182/blood-2023-174075

Published: 2023

Journal Articles

Single Cell Multi-Omic Correlation of Single Nucleotide Variants, Copy Number Variation and Surface Epitopes for Clonal Profiling of Myeloma

Adam Sciambi, Cedric Dos Santos, Yang Li, Joanne Bio Nguyen, Priyam Priyam, Vivek Chopra, Habib Hamidi, Michael Nixon, Yann Nouet, Todd E. Druley, Herve Avet-Loiseau

Blood (2023) 142 (Supplement 1): 4714.

https://doi.org/10.1182/blood-2023-189518

Published: 2023

Journal Articles

Stratification of Multiple Myeloma Patients in the Commpass Study By Single Cell Transcriptomics of Plasma Cells Associates with Clinical Outcome

Alireza Tafazzol, Xiangnan Guan, Giovanni Diaz, Minfang Song, Wenjin Li, Cedric Dos Santos, Habib Hamidi

Blood (2023) 142 (Supplement 1): 762.

https://doi.org/10.1182/blood-2023-180258

Published: 2023

Journal Articles

Engraftment of Human MDS Samples in Xenotransplanted Mice Depends on Human Cytokines but Not Mesenchymal Stem Cells (MSC)

Maria Krevvata, MSc, PhD, Cedric Dos Santos, PhD, Xiaochuan Shan, PhD MD, Selene Nunez-Cruz, PhD, Anthony Secreto, Michael Milone, MD PhD, Gwenn Danet-Desnoyers, PhD, Martin Carroll, MD

Blood (2016) 128 (22): 1980.

https://doi.org/10.1182/blood.V128.22.1980.1980

Published: 2016

Journal Articles

Development of a Patient-Derived Xenograft Model of Human Myelodysplastic Syndromes

Maria Krevvata, PhD, Cedric Dos Santos, PhD, Xiaochuan Shan, PhD MD, Anthony Secreto, Gwenn Danet-Desnoyers, PhD, Martin Carroll, MD

Blood (2015) 126 (23): 5217.

https://doi.org/10.1182/blood.V126.23.5217.5217

Published: 2015

Journal Articles

The Combination of the Novel Syk Inhibitor TAK659 with Decitabine Exerts Synergistic Cytotoxic Effects Against FLT3/ITD Mutated Acute Myeloid Leukemia Cells

Edwin Stage, MS, Magdalena Czader, MD PhD, Heather O'Leary, PhD, H. Scott Boswell, MD, Larry D. Cripe, MD, Hamid Sayar, MD, Cedric Dos Santos, PhD, Mark J. Levis, MD PhD, Heiko Konig, MDPhD

Blood (2015) 126 (23): 4928.

https://doi.org/10.1182/blood.V126.23.4928.4928

Published: 2015

Journal Articles

Combination of Dasatinib with Conventional Chemotherapy Is Associated with a High Response Rate in High Risk Acute Myeloid Leukemia (AML)

Blood (2015) 126 (23): 3743.

https://doi.org/10.1182/blood.V126.23.3743.3743

Published: 2015

Journal Articles

Improved Patient-Derived Xenograft Model for Acute Myeloid Leukemia

Xiaochuan Shan, MDPhD, Cedric Dos Santos, PhD, Chenghui Zhou, Georges Habineza Ndikuyeze, Anthony Secreto, Joshua Glover, Winifred Trotman, MS, Martin Carroll, MD, Gwenn Danet-Desnoyers, PhD

Blood (2014) 124 (21): 3491.

https://doi.org/10.1182/blood.V124.21.3491.3491

Published: 2014

Journal Articles

Bone Marrow Stromal Cells Protect Both FLT3-ITD and FLT3-WT Primary AML Cells from the Anti-Leukemic Activity of the FLT3 Inhibitor AC220

Cedric Dos Santos, PhD, Georges Habineza Ndikuyeze, Michael Nisssan, Chenghui Zhou, Xiaochuan Shan, MDPhD, Alexander E. Perl, MD, Martin P. Carroll, MD, Gwenn Danet-Desnoyers, PhD

Blood (2014) 124 (21): 4377.

https://doi.org/10.1182/blood.V124.21.4377.4377

Published: 2014

Journal Articles

Anti-Leukemic Activity of Daratumumab in Acute Myeloid Leukemia Cells and Patient-Derived Xenografts

Cedric Dos Santos, PhD, Shan Xiaochuan, MDPhD, Zhou Chenghui, Georges Habineza Ndikuyeze, Joshua Glover, Tony Secreto, Parul Doshi, PhD, Kate Sasser, Gwenn Danet-Desnoyers, PhD

Blood (2014) 124 (21): 2312.

https://doi.org/10.1182/blood.V124.21.2312.2312

Published: 2014

Journal Articles

Leukemia cell–targeted STAT3 silencing and TLR9 triggering generate systemic antitumor immunity

Dewan Md Sakib Hossain, Cedric Dos Santos, Qifang Zhang, Anna Kozlowska, Hongjun Liu, Chan Gao, Dayson Moreira, Piotr Swiderski, Agnieszka Jozwiak, Justin Kline, Stephen Forman, Ravi Bhatia, Ya-Huei Kuo, Marcin Kortylewski

Blood (2014) 123 (1): 15–25.

https://doi.org/10.1182/blood-2013-07-517987

Published: 2014

Includes: Supplemental data

Journal Articles

In Vivo Targeting Of Acute Myeloid Leukemia Using CpG- Stat3 siRNA Results In T Cell-Dependent Tumor Eradication

Dewan Md Sakib Hossain, PhD, Cedric Dos Santos, PhD, Qifang Zhang, PhD, Anna Kozlowska, PhD, Hongjun Liu, Chan Gao, PhD, Dayson Moreira, PhD, Piotr Swiderski, PhD, Agnieszka Jozwiak, Justin Kline, MD, Stephen J. Forman, MD, Ravi Bhatia, MD, Ya-Huei Kuo, PhD, Marcin Kortylewski, PhD

Blood (2013) 122 (21): 4212.

https://doi.org/10.1182/blood.V122.21.4212.4212

Published: 2013

Journal Articles

Pharmacological Inhibition Of The SIRT1 Deacetylase With The Small Molecule Inhibitor Tenovin-6 Enhances Ablation Of FLT3-ITD+ LSC In Combination With TKI Treatment

Ling Li, PhD, Tereza Osdal, MSc, YinWei Ho, MA, Tinisha McDonald, Sookhee Chun, Su Chu, MD, Allen Lin, Cedric Dos Santos, Ph.D, Mihaela Lucia Popa, VMD, Bjorn T Gjertsen, MD PhD, Wenyong Chen, PhD, Sonia Lain, Emmet McCormack, PhD, Ravi Bhatia, MD

Blood (2013) 122 (21): 2685.

https://doi.org/10.1182/blood.V122.21.2685.2685

Published: 2013

Journal Articles

Selective Anti Leukemic Activity Of Low Dose Decitabine In Combination With Ruxolitinib Against Stem/Progenitor Cells From Elderly AML Patients

Cedric Dos Santos, Ph.D, Puneet Agarwal, McDonald Tinisha, Allen Lin, Stephen J. Forman, MD, Ya-Huei Kuo, PhD, Ravi Bhatia, MD

Blood (2013) 122 (21): 2690.

https://doi.org/10.1182/blood.V122.21.2690.2690

Published: 2013

Journal Articles

T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia

Armen Mardiros, Cedric Dos Santos, Tinisha McDonald, Christine E. Brown, Xiuli Wang, L. Elizabeth Budde, Lauren Hoffman, Brenda Aguilar, Wen-Chung Chang, William Bretzlaff, Brenda Chang, Mahesh Jonnalagadda, Renate Starr, Julie R. Ostberg, Michael C. Jensen, Ravi Bhatia, Stephen J. Forman

Blood (2013) 122 (18): 3138–3148.

https://doi.org/10.1182/blood-2012-12-474056

Published: 2013

Includes: Supplemental data

Journal Articles

The Src and c-Kit kinase inhibitor dasatinib enhances p53-mediated targeting of human acute myeloid leukemia stem cells by chemotherapeutic agents

Cedric Dos Santos, Tinisha McDonald, Yin Wei Ho, Hongjun Liu, Allen Lin, Stephen J. Forman, Ya-Huei Kuo, Ravi Bhatia

Blood (2013) 122 (11): 1900–1913.

https://doi.org/10.1182/blood-2012-11-466425

Published: 2013

Includes: Supplemental data

Journal Articles

FLT3-ITD+ AML Stem/Progenitor Cells Demonstrate Increased SIRT1 Expression and Enhanced Sensitivity to SIRT1 Inhibition

Ling Li, PhD, Tinisha McDonald, Liang Li, PhD, Sookhee Chun, Cedric Dos Santos, Ph.D, YinWei Ho, Ravi Bhatia, MD

Blood (2012) 120 (21): 1368.

https://doi.org/10.1182/blood.V120.21.1368.1368

Published: 2012

Journal Articles

Dasatinib Enhances Targeting of Human AML Leukemia Stem Cells by Chemotherapeutic Agents Via Activation of p53

Cedric Dos Santos, Ph.D, Tinisha McDonald, YinWei Ho, Liu Hongjun, Allen Lin, Stephen J Forman, MD, Kuo Ya-Huei, Ph.D, Ravi Bhatia, MD

Blood (2012) 120 (21): 3590.

https://doi.org/10.1182/blood.V120.21.3590.3590

Published: 2012

Journal Articles

CD123-Specific Chimeric Antigen Receptor Redirected T Cells Exhibit Potent Cytolytic Activity and Multiple Effector Functions Against Acute Myeloid Leukemia without Altering Normal Hematopoietic Colony Formation in Vitro

Armen Mardiros, MS, Cedric Dos Santos, Ph.D, Tinisha McDonald, BS, Christine Brown, PhD, Xiuli Wang, MD, PhD, Wen-Chung Chang, MS, Julie R Ostberg, Ph.D, Ravi Bhatia, MD, Michael C. Jensen, MD, Stephen J. Forman, MD

Blood (2012) 120 (21): 950.

https://doi.org/10.1182/blood.V120.21.950.950

Published: 2012

NARROW

Using Single Cell Multi-Omic Clonal Tracking in SMM to Identify Clones That Progress to MM and Harbor Treatment Resistance Features

Integrative Analysis of the Tumor and Microenvironment to Model the Molecular Heterogeneity Underlying the Response to Cevostamab in Relapsed/Refractory Multiple Myeloma

Single Cell Multi-Omic Correlation of Single Nucleotide Variants, Copy Number Variation and Surface Epitopes for Clonal Profiling of Myeloma

Stratification of Multiple Myeloma Patients in the Commpass Study By Single Cell Transcriptomics of Plasma Cells Associates with Clinical Outcome

Engraftment of Human MDS Samples in Xenotransplanted Mice Depends on Human Cytokines but Not Mesenchymal Stem Cells (MSC)

Development of a Patient-Derived Xenograft Model of Human Myelodysplastic Syndromes

The Combination of the Novel Syk Inhibitor TAK659 with Decitabine Exerts Synergistic Cytotoxic Effects Against FLT3/ITD Mutated Acute Myeloid Leukemia Cells

Combination of Dasatinib with Conventional Chemotherapy Is Associated with a High Response Rate in High Risk Acute Myeloid Leukemia (AML)

Improved Patient-Derived Xenograft Model for Acute Myeloid Leukemia

Bone Marrow Stromal Cells Protect Both FLT3-ITD and FLT3-WT Primary AML Cells from the Anti-Leukemic Activity of the FLT3 Inhibitor AC220

Anti-Leukemic Activity of Daratumumab in Acute Myeloid Leukemia Cells and Patient-Derived Xenografts

Leukemia cell–targeted STAT3 silencing and TLR9 triggering generate systemic antitumor immunity

In Vivo Targeting Of Acute Myeloid Leukemia Using CpG- Stat3 siRNA Results In T Cell-Dependent Tumor Eradication

Pharmacological Inhibition Of The SIRT1 Deacetylase With The Small Molecule Inhibitor Tenovin-6 Enhances Ablation Of FLT3-ITD+ LSC In Combination With TKI Treatment

Selective Anti Leukemic Activity Of Low Dose Decitabine In Combination With Ruxolitinib Against Stem/Progenitor Cells From Elderly AML Patients

T cells expressing CD123-specific chimeric antigen receptors exhibit specific cytolytic effector functions and antitumor effects against human acute myeloid leukemia

The Src and c-Kit kinase inhibitor dasatinib enhances p53-mediated targeting of human acute myeloid leukemia stem cells by chemotherapeutic agents

FLT3-ITD+ AML Stem/Progenitor Cells Demonstrate Increased SIRT1 Expression and Enhanced Sensitivity to SIRT1 Inhibition

Dasatinib Enhances Targeting of Human AML Leukemia Stem Cells by Chemotherapeutic Agents Via Activation of p53

CD123-Specific Chimeric Antigen Receptor Redirected T Cells Exhibit Potent Cytolytic Activity and Multiple Effector Functions Against Acute Myeloid Leukemia without Altering Normal Hematopoietic Colony Formation in Vitro

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American Society of Hematology

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ASH Publications

American Society of Hematology

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