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Journal Articles

Single-Cell Multi-Omic Analysis of AML MRD Reveals Differences in Clonal Architecture between Relapse and Non-Relapse Cases

Adam Sciambi, Daniel Mendoza, Kathryn Thompson, Lan W. Beppu, Benjamin Geller, Indira Krishnan, Lubna Nousheen, Shu Wang, Charlie Murphy, Jerald P. Radich, Todd E. Druley

Blood (2024) 144 (Supplement 1): 1568.

https://doi.org/10.1182/blood-2024-210840

Published: 2024

Journal Articles

Using Single Cell Multi-Omic Clonal Tracking in SMM to Identify Clones That Progress to MM and Harbor Treatment Resistance Features

Adam Sciambi, Daniel Mendoza, Indira Krishnan, Joanne Nguyen, Lubna Nousheen, Benjamin Geller, Cedric Dos Santos, Vivek S. Chopra, Habib Hamidi, Michael Nixon, Yann Nouet, Todd E. Druley, Herve Avet-Loiseau

Blood (2024) 144 (Supplement 1): 4722.

https://doi.org/10.1182/blood-2024-205533

Published: 2024

Journal Articles

A Multiomic, Single-Cell Measurable Residual Disease (scMRD) Assay for Simultaneous Assessment of DNA Mutations and Surface Immunophenotypes in Acute Myeloid Leukemia

Kathryn Thompson, Benjamin Geller, Lubna Nousheen, Indira Krishnan, Shu Wang, Daniel Mendoza, Todd E. Druley, Adam Sciambi

Blood (2024) 144 (Supplement 1): 6168.

https://doi.org/10.1182/blood-2024-204025

Published: 2024

Journal Articles

Single Cell Multi-Omic Correlation of Single Nucleotide Variants, Copy Number Variation and Surface Epitopes for Clonal Profiling of Myeloma

Adam Sciambi, Cedric Dos Santos, Yang Li, Joanne Bio Nguyen, Priyam Priyam, Vivek Chopra, Habib Hamidi, Michael Nixon, Yann Nouet, Todd E. Druley, Herve Avet-Loiseau

Blood (2023) 142 (Supplement 1): 4714.

https://doi.org/10.1182/blood-2023-189518

Published: 2023

Journal Articles

A Multiomic, Single-Cell Measurable Residual Disease (scMRD) Assay for Phasing DNA Mutations and Surface Immunophenotypes

Charlie Murphy, Kate Thompson, Lubna Nousheen, Divya Rao, Todd E. Druley

Blood (2023) 142 (Supplement 1): 6055.

https://doi.org/10.1182/blood-2023-189360

Published: 2023

Journal Articles

High-Dose Cytarabine Is Indispensable for the Survival of Children with Myeloid Leukemia of Down Syndrome Despite Negative Minimal Residual Disease Post-Induction

Johann K. Hitzler, MD, Jason Berman, MD, Robert B. Gerbing, Amy Beckman, Betsy A Hirsch, PhD, Susana C. Raimondi, PhD, Todd E Druley, MD PhD, Michael R. Loken, PhD, Lisa Eidenschink Brodersen, PhD, Karen Chisholm, Shelton A. Viola, MD, Jeffrey W. Taub, MD, Alan S Gamis, MD MPH, Todd A. Alonzo, PhD, E. Anders Kolb, MD

Blood (2019) 134 (Supplement_1): 118.

https://doi.org/10.1182/blood-2019-126723

Published: 2019

Journal Articles

Generation, Characterization and Pre-Clinical Drug Evaluation of Patient-Derived Xenograft Models of Pediatric Down Syndrome AML

Sonali Barwe, PhD MSc, E. Anders Kolb, MD, Erin Lynn Crowgey, PhD, Todd E Druley, MD PhD, Anilkumar Gopalakrishnapillai, PhD

Blood (2019) 134 (Supplement_1): 2683.

https://doi.org/10.1182/blood-2019-131050

Published: 2019

Journal Articles

The Clonal Hematopoietic Spectrum of Down Syndrome and ML-DS

R. Spencer Tong, BA, Wing Hing Wong, BSc, David R. O'Leary, Kathleen S. Jay, MS, RN, PNP-BC, D. Katherine Grange, MD, Jason Berman, MD, Johann K. Hitzler, MD, Todd E Druley, MD PhD

Blood (2018) 132 (Supplement 1): 3839.

https://doi.org/10.1182/blood-2018-99-120168

Published: 2018

Journal Articles

Investigating the Effects of Clonal Hematopoiesis in Healthy Marrow and Blood Donors on the Outcomes of Recipients Following Hematopoietic Stem Cell Transplantation

Wing Hing Wong, BSc, Kevin Elliot, Iskra Pusic, MD, John F. DiPersio, MD PhD, Todd E Druley, MD PhD

Blood (2018) 132 (Supplement 1): 2180.

https://doi.org/10.1182/blood-2018-99-115427

Published: 2018

Journal Articles

Utility of Detecting Rare Clonal Hematopoiesis for Predicting Leukemic Transformation in Healthy Individuals

Andrew L Young, BA, Spencer Tong, BA, Tianyi Huang, MSc, ScD, Brenda M Birmann, ScD, Todd E Druley, MD PhD

Blood (2017) 130 (Supplement 1): 304.

https://doi.org/10.1182/blood.V130.Suppl_1.304.304

Published: 2017

Journal Articles

Error-Corrected Sequencing of Cord Bloods Identifies Pediatric AML-Associated Clonal Hematopoiesis

Wing Hing Wong, BSc, Spencer Tong, BA, Todd E Druley, MD PhD

Blood (2017) 130 (Supplement 1): 2687.

https://doi.org/10.1182/blood.V130.Suppl_1.2687.2687

Published: 2017

Journal Articles

Human definitive hematopoietic specification from pluripotent stem cells is regulated by mesodermal expression of CDX4

J. Philip Creamer, Carissa Dege, Qihao Ren, Jolie T. K. Ho, Mark C. Valentine, Todd E. Druley, Christopher M. Sturgeon

Blood (2017) 129 (22): 2988–2992.

https://doi.org/10.1182/blood-2016-11-749382

Published: 2017

Includes: Supplemental data

Journal Articles

Novel Technologies to Detect Minimal Residual Disease

Todd E. Druley, MD PhD

Blood (2016) 128 (22): SCI-31.

https://doi.org/10.1182/blood.V128.22.SCI-31.SCI-31

Published: 2016

Journal Articles

Infants with Leukemia Exhibit Compound Heterozygosity for Deleterious Germline Variation in MLL3 Independent of MLL-Rearrangements

Mark C Valentine, BS, Elizabeth L Ostrander, BS, Amy Linabery, PhDMS, Logan G. Spector, PhD, Julie A. Ross, PhD, Todd E Druley, MDPhD

Blood (2014) 124 (21): 485.

https://doi.org/10.1182/blood.V124.21.485.485

Published: 2014

Journal Articles

Rare Hematopoietic Subclones Harboring Leukemogenic TP53 Mutations Are Detectable Via Error-Corrected Sequencing in Healthy Elderly Individuals

Andrew Young, B.A., Terrence Neal Wong, MD PhD, Timothy J Ley, MD, Daniel C. Link, MD, Todd E Druley, MD PhD

Blood (2014) 124 (21): 2907.

https://doi.org/10.1182/blood.V124.21.2907.2907

Published: 2014

Journal Articles

Young Paternal Age and Risk Of Infant Acute Lymphoblastic Leukemia

Julie A Ross, PhD, Todd E Druley, MD, PhD, Kimberly J Johnson, Rachel K. Fonstad, M.S., Julie von Behren, MPH, Beth Mueller, PhD, Susan Carozza, PhD, Eric J. Chow, MD, MPH, Colleen McLaughlin, PhD, Peggy Reynolds, PhD, Erin Fox, PhD, Scott Horel, Logan G. Spector, PhD

Blood (2013) 122 (21): 1395.

https://doi.org/10.1182/blood.V122.21.1395.1395

Published: 2013

Journal Articles

The Role Of Early TP53 Mutations On The Evolution Of Therapy-Related AML

Terrence Neal Wong, MD PhD, Giridharan Ramsingh, M.D, Andrew Young, Dong Shen, Chris Miller, PhD, Tamara Lamprecht, B.S., Sharon Heath, Robert S. Fulton, Elaine R. Mardis, PhD, Li Ding, Peter Westervelt, MD, PhD, John Welch, PhD/MD, Matthew J. Walter, MD, Timothy Graubert, MD, John F. DiPersio, MD, PhD, Timothy J. Ley, MD, Todd E Druley, MD, PhD, Richard K Wilson, PhD, Daniel C. Link, MD

Blood (2013) 122 (21): 5.

https://doi.org/10.1182/blood.V122.21.5.5

Published: 2013

Journal Articles

Germline Exome Sequencing From MLL -Negative Infant AML Patients Reveals Compound Heterozygosity For Novel, Non-Synonymous Alleles Of MLL3 : A Report From The Children’s Oncology Group (COG)

Mark C. Valentine, Amy M. Linabery, PhD, MS, Logan G. Spector, PhD, Julie A Ross, PhD, Todd E Druley, MD, PhD

Blood (2013) 122 (21): 62.

https://doi.org/10.1182/blood.V122.21.62.62

Published: 2013

Journal Articles

Matched Exome Sequencing in Mothers and Infants with MLL-Negative Acute Leukemia

Todd E. Druley, MD, PhD, Mark Valentine, Nicholas Sanchez, Julie A. Ross, PhD

Blood (2012) 120 (21): 536.

https://doi.org/10.1182/blood.V120.21.536.536

Published: 2012

Journal Articles

Characterizing Rare Variants in Drug Metabolism Genes in Refractory Pediatric High-Risk Pre-B ALL

Andrew Hughes, Joseph Giacalone, Todd E Druley, MD, PhD

Blood (2012) 120 (21): 879.

https://doi.org/10.1182/blood.V120.21.879.879

Published: 2012

NARROW

Single-Cell Multi-Omic Analysis of AML MRD Reveals Differences in Clonal Architecture between Relapse and Non-Relapse Cases

Using Single Cell Multi-Omic Clonal Tracking in SMM to Identify Clones That Progress to MM and Harbor Treatment Resistance Features

A Multiomic, Single-Cell Measurable Residual Disease (scMRD) Assay for Simultaneous Assessment of DNA Mutations and Surface Immunophenotypes in Acute Myeloid Leukemia

Single Cell Multi-Omic Correlation of Single Nucleotide Variants, Copy Number Variation and Surface Epitopes for Clonal Profiling of Myeloma

A Multiomic, Single-Cell Measurable Residual Disease (scMRD) Assay for Phasing DNA Mutations and Surface Immunophenotypes

High-Dose Cytarabine Is Indispensable for the Survival of Children with Myeloid Leukemia of Down Syndrome Despite Negative Minimal Residual Disease Post-Induction

Generation, Characterization and Pre-Clinical Drug Evaluation of Patient-Derived Xenograft Models of Pediatric Down Syndrome AML

The Clonal Hematopoietic Spectrum of Down Syndrome and ML-DS

Investigating the Effects of Clonal Hematopoiesis in Healthy Marrow and Blood Donors on the Outcomes of Recipients Following Hematopoietic Stem Cell Transplantation

Utility of Detecting Rare Clonal Hematopoiesis for Predicting Leukemic Transformation in Healthy Individuals

Error-Corrected Sequencing of Cord Bloods Identifies Pediatric AML-Associated Clonal Hematopoiesis

Human definitive hematopoietic specification from pluripotent stem cells is regulated by mesodermal expression of CDX4

Novel Technologies to Detect Minimal Residual Disease

Infants with Leukemia Exhibit Compound Heterozygosity for Deleterious Germline Variation in MLL3 Independent of MLL-Rearrangements

Rare Hematopoietic Subclones Harboring Leukemogenic TP53 Mutations Are Detectable Via Error-Corrected Sequencing in Healthy Elderly Individuals

Young Paternal Age and Risk Of Infant Acute Lymphoblastic Leukemia

The Role Of Early TP53 Mutations On The Evolution Of Therapy-Related AML

Germline Exome Sequencing From MLL -Negative Infant AML Patients Reveals Compound Heterozygosity For Novel, Non-Synonymous Alleles Of MLL3 : A Report From The Children’s Oncology Group (COG)

Matched Exome Sequencing in Mothers and Infants with MLL-Negative Acute Leukemia

Characterizing Rare Variants in Drug Metabolism Genes in Refractory Pediatric High-Risk Pre-B ALL

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American Society of Hematology

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ASH Publications

American Society of Hematology

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