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Journal Articles

Spred1 Insufficiency in the Hematopoietic and/or Vascular Compartments of the Bone Marrow (BM) Niche Promotes Aggressive Leukemogenesis in Chronic Myelogenous Leukemia (CML)

Junjing Qiao, MD PhD, Dandan Zhao, MD, Le Xuan Truong Nguyen, PhD, Herman Wu, BS, Gang Liu, PhD, Shanshan Suo, MD, Huafeng Wang, Yasmin Elhajmoussa, Chen Liang, MD, David Snyder, MD, Haris Ali, MD, Steven Rosen, MD, Nadia Carlesso, MD, Ling Li, PhD, Ya-Huei Kuo, PhD, Guido Marcucci, MD, Bin Zhang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3791.
https://doi.org/10.1182/blood-2019-127616
Published: 2019
Journal Articles

Anti-MiR-126 Therapy for Inv(16) Acute Myeloid Leukemia

Lianjun Zhang, PhD, Le Xuan Truong Nguyen, PhD, Dijiong Wu, MD, Casey J Brewer, PhD, Xin He, PhD, Man Li, PhD, Dandan Zhao, MD, Guerry Jeanne Cook, PhD, Jing Qi, PhD, Herman Wu, BS, Bin Zhang, PhD, Ling Li, PhD, Marcin Kortylewski, PhD, Guido Marcucci, MD, Ya-Huei Kuo, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3914.
https://doi.org/10.1182/blood-2019-123468
Published: 2019
Journal Articles

Targeting MiR-126 Blocks Progression of Myelodysplastic Syndrome and Transformation into Acute Myeloid Leukemia

Huafeng Wang, MD, Jie Sun, PhD, Dandan Zhao, MD, Hongyan Tong, Herman Wu, BS, Xia Li, PhD, Yingwan Luo, MD, Dan Dong, PhD, Tinisha McDonald, MS, Anthony Stein, MD, Monzr M. Al Malki, MD, Flavia Pichiorri, PhD, Nadia Carlesso, MD, Ya-Huei Kuo, PhD, Bin Zhang, PhD, Guido Marcucci, MD, Ling Li, PhD, Jie Jin, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1707.
https://doi.org/10.1182/blood-2019-130375
Published: 2019
Journal Articles

PRMT1-mediated FLT3 arginine methylation promotes maintenance of FLT3-ITD + acute myeloid leukemia

Xin He, Yinghui Zhu, Yi-Chun Lin, Min Li, Juan Du, Haojie Dong, Jie Sun, Lei Zhu, Hanying Wang, Zonghui Ding, Lei Zhang, Lianjun Zhang, Dandan Zhao, Zhihao Wang, Herman Wu, Han Zhang, Wenjuan Jiang, Yang Xu, Jian Jin, Yudao Shen, Jeff Perry, Xinyang Zhao, Bin Zhang, Songbai Liu, Sheng-Li Xue, Binghui Shen, Chun-Wei Chen, Jianjun Chen, Samer Khaled, Ya-Huei Kuo, Guido Marcucci, Yun Luo, Ling Li
Journal: Blood
Blood (2019) 134 (6): 548–560.
https://doi.org/10.1182/blood.2019001282
Published: 2019
Includes: Supplemental data
Journal Articles

Downregulation of Mir-142 Promotes Leukemia Growth in Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL): A Possible Novel Therapeutic Target?

Huafeng Wang, Bin Zhang, PhD, Wei-Le Wang, BS, Dandan Zhao, MD, Ling Li, PhD, Herman Wu, BS, Le Xuan Truong Nguyen, PhD, Weixu Meng, MD PhD, Tinisha McDonald, MS, Flavia Pichiorri, PhD, Ya-Huei Kuo, PhD, Jianjun Chen, PhD, Nadia Carlesso, MD PhD, Ibrahim Aldoss, MD, Vinod A. Pullarkat, MD, Monzr Al Malki, MD, Anthony S. Stein, MD, Mark Boldin, MD PhD, Jie Jin, MD PhD, Guido Marcucci
Journal: Blood
Blood (2018) 132 (Supplement 1): 1338.
https://doi.org/10.1182/blood-2018-99-119599
Published: 2018
Journal Articles

PNC ¯ 27 Targeting Plasma Membrane HDM2: A Potentially Novel Therapeutic Approach for Acute Myeloid Leukemia (AML)

Huafeng Wang, Bin Zhang, PhD, Dandan Zhao, MD, Estelle Troadec, PhD, Weixu Meng, PhD MD, Allen Lin, Anthony S. Stein, MD, Monzr M. Al Malki, MD, Herman Wu, BS, Tinisha Mcdonald, Jie Jin, Guido Marcucci, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2518.
https://doi.org/10.1182/blood.V130.Suppl_1.2518.2518
Published: 2017
Journal Articles

Anti-IL1RAP/CD3 Bispecific Antibody (BsAb) Is a Promising Novel and Effective Therapy for Acute Myeloid Leukemia (AML)

Weixu Meng, MD PhD, Marissa Del Real, PhD, Guowei Wei, PhD, Rochelle Hernandez, Emanuela Marcucci, Allen Lin, Tinisha Mcdonald, Dandan Zhao, MD, Herman Wu, BS, Nadia Carlesso, MD PhD, Larry W Kwak, MDPhD, Ling Li, PhD, Ya-Huei Kuo, PhD, Anthony S. Stein, MD, Vinod Pullarkat, MD MRCP, Ryotaro Nakamura, MD, Steven T. Rosen, MD, Stephen J. Forman, MD FACP, Bin Zhang, PhD, Lihua Budde, MD PhD, Guido Marcucci, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1361.
https://doi.org/10.1182/blood.V130.Suppl_1.1361.1361
Published: 2017
Journal Articles

Activation of SIRT1 Deacetylase As a Therapeutic Approach for Myelodysplastic Syndromes By Restoring TET2 Function

Jie Sun, PhD, Yinghui Zhu, PhD, Xin He, MD, Zonghui Ding, PhD, Haojie DONG, PhD, Yimei Feng, MD PhD, Xiaochun Yu, MD PhD, Dandan Zhao, MD, Herman Wu, BS, Lifeng Feng, PhD, Kaoru Tohyama, MD, Hongchuan Jin, MD PhD, Philipp Oberdoerffer, PhD, Yang Jo Chung, PhD, Peter D. Aplan, MD, Bin Zhang, PhD, Ya-Huei Kuo, PhD, Ravi Bhatia, MD, Andrea Pellagatti, PhD, Jacqueline Boultwood, PhD, Nadia Carlesso, MD PhD, Guido Marcucci, MD, Ling Li, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2497.
https://doi.org/10.1182/blood.V130.Suppl_1.2497.2497
Published: 2017
Journal Articles

TET2 Activity Is Modulated By SIRT1-Mediated Protein Deacetylation: A Potential Therapeutic Target in Myelodysplastic Syndrome

Jie Sun, MS, Yinghui Zhu, PhD, Zonghui Ding, PhD, Haojie Dong, PhD, Yimei Feng, PhD MD, Qiang Chen, PhD, Xiaochun Yu, PhD MD, Dandan Zhao, MD, Herman Wu, BS, Lifeng Feng, PhD, Kaoru Tohyama, MD PhD, Philipp Oberdoerffer, PhD, Bin Zhang, PhD, Ya-Huei Kuo, PhD, Ravi Bhatia, MD, Hongchuan Jin, PhD MD, Guido Marcucci, MD, Ling Li, PhD
Journal: Blood
Blood (2016) 128 (22): 1053.
https://doi.org/10.1182/blood.V128.22.1053.1053
Published: 2016
Journal Articles

Time Sequential Transcriptome Analysis Identifies Mir-126 As an Early Biomarker for Inv(16) Acute Myeloid Leukemia (AML) Disease Progression

Jing Qi, PhD, Guerry J Cook, Bin Zhang, PhD, Wei-Kai Hua, PhD, Cai Qi, Emily Carnahan, Ayelet Marom, Le Xuan Truong Nguyen, Yang Lu, Sergio Branciamore, Herman Wu, BS, Yate-Ching Yuan, Xiwei Wu, PhD, Ling Li, PhD, Anthony S. Stein, MD, Russell Rockne, Marcin Kortylewski, PhD, Guido Marcucci, MD, Ya-Huei Kuo, PhD
Journal: Blood
Blood (2016) 128 (22): 773.
https://doi.org/10.1182/blood.V128.22.773.773
Published: 2016