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Journal Articles

Randomized Phase II Trial of Dendritic Cell/AML Fusion Cell Vaccination Compared to Standard of Care Therapy in AML CR1

Prateek Pophali, Giulia Cheloni, Richard M. Stone, Kai W Wucherpfennig, Aric C. Hall, Amir T. Fathi, Lina Bisharat, Emma K Logan, Yiwen Liu, Donna S. Neuberg, Malgorzata McMasters, Jessica Liegel, Jacqueline S. Garcia, Daniel J. DeAngelo, Michele Narcis, Dina Stroopinsky, Pavania Elavalakanar, Ioannis S Vlachos, Ilene A. Galinsky, Jason Pyrdol, Georges Chedid, Dimitra Karagkouni, Shivani Nanda, Kathrine S Rallis, Isabella Saldarriaga, Hazal Toros, Haitham Abdelhakim, Amelia Langston, Joseph P. McGuirk, Donald Kufe, David Avigan, Jacalyn Rosenblatt
Journal: Blood
Blood (2024) 144 (Supplement 1): 4256.
https://doi.org/10.1182/blood-2024-200876
Published: 2024
Journal Articles

Phase 2 clinical trial evaluating abatacept in patients with steroid-refractory chronic graft-versus-host disease

CME Clinical Trials & Observations
Anita G. Koshy, Haesook T. Kim, Jessica Liegel, Jon Arnason, Vincent T. Ho, Joseph H. Antin, Robin Joyce, Corey Cutler, Mahasweta Gooptu, Sarah Nikiforow, Emma K. Logan, Pavania Elavalakanar, Michele Narcis, Dina Stroopinsky, Zachary M. Avigan, Leora Boussi, Susan Stephenson, Hassan El Banna, Poorva Bindal, Giulia Cheloni, David E. Avigan, Robert J. Soiffer, Jacalyn Rosenblatt
Journal: Blood
Blood (2023) 141 (24): 2932–2943.
https://doi.org/10.1182/blood.2022019107
Published: 2023
Includes: Supplemental data
Journal Articles

Durable Response to CD19 CAR T Cell Therapy Is Associated with Cytotoxicity and Clonotypic Expansion of the Native T Cell Repertoire

Giulia Cheloni, Dimitra Karagkouni, Yered Pita-Juarez, Daniela Torres, Eleni Kanata, Zachary M. Avigan, Jessica Liegel, Dina Stroopinsky, Brodie Miles, Gayatri Tiwari, Jenny Kim, Mike Mattie, Jacalyn Rosenblatt, David Avigan, Ioannis Vlachos
Journal: Blood
Blood (2022) 140 (Supplement 1): 644–645.
https://doi.org/10.1182/blood-2022-169230
Published: 2022
Journal Articles

Treatment with DC/AML Fusion Vaccine and CD3xCD123 Bi-Specific T-Cell Engager (CD123-CODV-TCE) for Treatment of Acute Myeloid Leukemia

Dina Stroopinsky, Anita G. Koshy, Jessica J. Liegel, Myrna Nahas, Giulia Cheloni, Joshua Hauser, Daniela Torres, Poorva Bindal, Maryam Rahimian, Lina Bisharat, Paula Fraenkel, Ozlem Yildirim, Helene Bonnevaux, Stephane Guerif, Donald Kufe, Jacalyn Rosenblatt, David Avigan
Journal: Blood
Blood (2021) 138 (Supplement 1): 904.
https://doi.org/10.1182/blood-2021-148219
Published: 2021
Journal Articles

Impact of Autologous Hematopoietic Cell Transplant (HCT) Followed By Dendritic Cell/Myeloma Fusion Vaccine with Lenalidomide Maintenance in Increasing Multiple Myeloma (MM) Immunity (BMT CTN 1401)

David J. Chung, Nina Shah, Dina Stroopinsky, Juan WU, Lina Bisharat, Natalie S. Callander, Brent R. Logan, Kenneth C. Anderson, Thinle Chodon, Meera Mohan, Steven Devine, Yvonne A. Efebera, Nancy Geller, Peiman Hematti, Leona A. Holmberg, Alan Howard, Bryon Johnson, Hillard M Lazarus, Ehsan Malek, Philip L. McCarthy, David H. McKenna, Adam M. Mendizabal, Nikhil C. Munshi, Lynn O'Donnell, Aaron P. Rapoport, Ajay K. Nooka, Jane Reese, Robert J. Soiffer, Lynne Uhl, Giulia Cheloni, Dimitra Karagkouni, Ioannis Vlachos, James W. Young, Jacalyn Rosenblatt, Edmund K. Waller, Marcelo C Pasquini, David Avigan
Journal: Blood
Blood (2021) 138 (Supplement 1): 899.
https://doi.org/10.1182/blood-2021-149659
Published: 2021
Journal Articles

Phase II Clinical Trial of Abatacept for Steroid-Refractory Chronic Graft Versus Host Disease

Anita G. Koshy, Haesook T. Kim, Dina Stroopinsky, Jessica J. Liegel, Jon E. Arnason, Vincent T. Ho, Joseph H. Antin, Robin M. Joyce, Corey Cutler, Mahasweta Gooptu, Sarah Nikiforow, Emma K. Logan, Pavania Elavalakanar, Susan Stephenson, Hassan El Banna, Poorva Bindal, Giulia Cheloni, David Avigan, Robert J. Soiffer, Jacalyn Rosenblatt
Journal: Blood
Blood (2021) 138 (Supplement 1): 264.
https://doi.org/10.1182/blood-2021-148343
Published: 2021
Journal Articles

Post-Transplant Vaccination with a Personalized Dendritic Cell/AML Fusion Cell Vaccine for Prevention of Relapse

Jessica J. Liegel, Poorva Bindal, Richard M. Stone, Robert J. Soiffer, Dina Stroopinsky, Giulia Cheloni, Lina Bisharat, Daniela Torres, Maryam Rahimian, Seo Yeon Yoo, Emma K. Logan, Pavania Elavalakanar, Hassan El Banna, Joshua Hauser, Anita G. Koshy, Rizwan Romee, Vincent T. Ho, Donna S. Neuberg, Yiwen Liu, Lourdes M. Mendez, Ajoy L. Dias, Benjamin L. Ebert, Donald Kufe, David Avigan, Jacalyn Rosenblatt
Journal: Blood
Blood (2021) 138 (Supplement 1): 2830.
https://doi.org/10.1182/blood-2021-154166
Published: 2021
Journal Articles

Fc Receptor-Dependent Trogocytosis of CD39 Impacts Engraftment and Invasiveness of Acute Myeloid Leukemia Cells

Lili Feng, Haohai Zhang, Paola de Andrade Mello, Dina Stroopinsky, Wenda Gao, David Avigan, Simon C. Robson
Journal: Blood
Blood (2021) 138 (Supplement 1): 3298.
https://doi.org/10.1182/blood-2021-151021
Published: 2021
Journal Articles

Synergism between CAR-T Cells and a Personalized Tumor Vaccine in Hematological Malignances

Giulia Cheloni, Marzia Capelletti, Daniela Torres, Poorva Bindal, Jessica J. Liegel, Dina Stroopinsky, Lina Bisharat, Maryam Rahimian, Seo Yeon Yoo, Joshua Hauser, Anita G. Koshy, Kenel Dufort, John G. Clohessy, Donald Kufe, Maria Themeli, Jacalyn Rosenblatt, Michel Sadelain, David Avigan
Journal: Blood
Blood (2021) 138 (Supplement 1): 737.
https://doi.org/10.1182/blood-2021-150307
Published: 2021
Journal Articles

Profiling the Peripheral Blood Immune Cell Repertoire in Large-B Cell Lymphoma Patients Treated with CD19 CAR-T

Giulia Cheloni, Eleni Kanata, Dina Stroopinsky, Dimitra Karagkouni, Jessica J. Liegel, Daniela Torres, Joshua Hauser, Poorva Bindal, Anita G. Koshy, Yered Pita-Juarez, Adrian Bot, Mike Mattie, Justin Chou, Jacalyn Rosenblatt, David Avigan, Ioannis Vlachos
Journal: Blood
Blood (2021) 138 (Supplement 1): 2786.
https://doi.org/10.1182/blood-2021-151459
Published: 2021
Journal Articles

Vaccination with a Personalized Dendritic Cell/AML Fusion Cell Vaccine Following Allogeneic Transplantation in a Phase 1 Clinical Trial

Jessica Liegel, MD, Richard M. Stone, MD, Robert J. Soiffer, MD, Dina Stroopinsky, PhD, Lina Bisharat, Maryam Rahimian, Emma Logan, Pavania Elavalakanar, MSc, BSc, Vincent T. Ho, MD, Rizwan Romee, MD, Donna S. Neuberg, ScD, Yiwen Liu, Lourdes M. Mendez, MD PhD, Ajoy L. Dias, MD, Poorva Bindal, MD, Anita Koshy, MD, Shira Orr, PhD, Daniela Torres, Giulia Cheloni, PhD, Benjamin L. Ebert, MDPhD, Donald Kufe, MD, David E. Avigan, MD, Jacalyn Rosenblatt, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10.
https://doi.org/10.1182/blood-2020-141634
Published: 2020
Journal Articles

CD155-Tigit Pathway Modulation in Dendritic Cell/Acute Myeloid Leukemia Fusion Vaccine Model

Myrna Nahas, MD, Dina Stroopinsky, PhD, Marzia Capelletti, PhD MBBS, Jacalyn Rosenblatt, MD, Shira Orr, PhD, Haider Ghiasuddin, Adam Morin, Jessica Liegel, MD, Donald Kufe, MD, David E. Avigan, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1386.
https://doi.org/10.1182/blood-2019-122438
Published: 2019
Journal Articles

Development of Novel Second Generation DC/Tumor Fusion Vaccine in Lymphoma

Shira Orr, PhD, Marzia Capelletti, PhD MBBS, Haider Ghiasuddin, Dina Stroopinsky, PhD, Jessica Liegel, MD, Myrna Nahas, MD, Matthew Weinstock, MD, Adam Morin, Robin M. Joyce, MD, Salvia Jain, MD, Jon E. Arnason, MD, Maryam Rahimian, MD, Lina Bisharat, Shufen Meng, MD, Donald Kufe, MD, Jacalyn Rosenblatt, MD, David E. Avigan, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 392.
https://doi.org/10.1182/blood-2019-124768
Published: 2019
Journal Articles

Transcriptome Sequencing Demonstrates Unique Signature Associated with Durable Clinical Response to DC/AML Fusion Vaccine

Jessica Liegel, MD, Manoj Bhasin, PhD, German A. Pihan, MD, Dina Stroopinsky, PhD, Beena Thomas, PhD, Shreya Sindhu, Haider Ghiasuddin, Emma Logan, Adam Morin, Marzia Capelletti, PhD MMSc, Shira Orr, PhD, Myrna Nahas, MD, Matthew Weinstock, MD, Maryam Rahimian, MD, Lina Bisharat, Shufen Meng, MD, Richard M. Stone, MD, Donald Kufe, MD, David E. Avigan, MD, Jacalyn Rosenblatt, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3832.
https://doi.org/10.1182/blood-2019-129451
Published: 2019
Journal Articles

T Cells Educated By DC/AML Fusions in the Context of 4-1BB Costimulation As a Potent Strategy for Adoptive Cellular Therapy

Jessica Liegel, MD, Dina Stroopinsky, PhD, Haider Ghiasuddin, Adam Morin, Marzia Capelletti, PhD MMSc, Shira Orr, PhD, Maryam Rahimian, MD, Lina Bisharat, Shufen Meng, MD, Myrna Nahas, MD, Matthew Weinstock, MD, Donald Kufe, MD, Jacalyn Rosenblatt, MD, David E. Avigan, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2673.
https://doi.org/10.1182/blood-2019-131491
Published: 2019
Journal Articles

Potent Synergy between Combination of Chimeric Antigen Receptor (CAR) Therapy Targeting CD19 in Conjunction with Dendritic Cell (DC)/Tumor Fusion Vaccine in Hematological Malignancies

Marzia Capelletti, PhD MMSc, Jessica Liegel, MD, Maria Themeli, MD PhD, Tuna Mutis, Dina Stroopinsky, PhD, Shira Orr, PhD, Daniela Torres, Adam Morin, Gertrude Gunset, BA, Haider Ghiasuddin, Maryam Rahimian, MD, Myrna Nahas, MD, Lina Bisharat, Shufen Meng, MD, Nikhil C. Munshi, MD, Donald Kufe, MD, Jacalyn Rosenblatt, MD, Michel Sadelain, MD PhD, David E. Avigan, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3227.
https://doi.org/10.1182/blood-2019-124944
Published: 2019
Journal Articles

Ex-Vivo Stimulation with DC/AML Fusion Vaccine in the Presence of Cytokines Leads to an Activated T Cell Memory Phenotype and Enhanced Cytotoxicity with Potential for Use As an Adoptive Cellular Therapy

Jessica Liegel, MD, Dina Stroopinsky, PhD, Lourdes M. Mendez, MD PhD, Malgorzata McMasters, MD, Haider Ghiasuddin, BA, Maryam Rahimian, MD, Myrna Nahas, MD, Matthew Weinstock, MD, Salvia Jain, MD, Marzia Capelletti, PhD MMSc, Lina Bisharat, MA, Adam Morin, BA, Shira Orr, PhD, Jacalyn Rosenblatt, MD, Donald Kufe, MD, David E. Avigan, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2728.
https://doi.org/10.1182/blood-2018-99-119996
Published: 2018
Journal Articles

A Novel Monoclonal Antibody Combination Plus DC/AML Fusion Vaccine Eradicates AML in an Immunocompetent Murine Model

Dina Stroopinsky, PhD, Jessica Liegel, MD, Kathleen M. Mahoney, MD PhD, Jacalyn Rosenblatt, MD, Benjamin L. Ebert, MD PhD, Richard M. Stone, MD, Maryam Rahimian, MD, Myrna Nahas, MD, Shira Orr, PhD, Marzia Capelletti, PhD MMSc, Matthew Weinstock, MD, Salvia Jain, MD, Lina Bisharat, MA, Haider Ghiasuddin, BA, Adam Morin, BA, Donald Kufe, MD, Gordon J Freeman, PhD, David E. Avigan, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1446.
https://doi.org/10.1182/blood-2018-99-120259
Published: 2018
Journal Articles

Phase 1 clinical trial evaluating abatacept in patients with steroid-refractory chronic graft-versus-host disease

Clinical Trials & Observations
Myrna R. Nahas, Robert J. Soiffer, Haesook T. Kim, Edwin P. Alyea, III, Jon Arnason, Robin Joyce, Joseph H. Antin, Vincent T. Ho, Dina Stroopinsky, Shuli Li, James D. Levine, Malgorzata McMasters, Salvia Jain, Ayad Hamdan, Dimitrios Tzachanis, Mary Paty Bryant, Emma K. Logan, Josie Bazemore, Jeremy Stewart, Amy Joyce, Susan Stephenson, Abigail Washington, Leandra Cole, Athalia Pyzer, Rebecca Karp Leaf, David E. Avigan, Jacalyn Rosenblatt
Journal: Blood
Blood (2018) 131 (25): 2836–2845.
https://doi.org/10.1182/blood-2017-05-780239
Published: 2018
Includes: Supplemental data
Journal Articles

Phase I/Ib Trial of the MUC1 Inhibitor GO-203-2C Alone and in Combination with Decitabine for Acute Myeloid Leukemia

Jessica Liegel, MD, Jacalyn Rosenblatt, MD, Richard M. Stone, MD, Malgorzata McMasters, MD, James D. Levine, MD MS, Myrna Nahas, MD, Robin M. Joyce, MD, Salvia Jain, MD, Daniel J. DeAngelo, MD, Jacqueline S. Garcia, MD, Josie Bazemore, Ilene Galinsky, Donna S. Neuberg, ScD, Lillian Werner, MS, Emma Logan, Kaleb Mikami, Mary Paty Bryant, Victoria Allen, Dina Stroopinsky, PhD, Leandra Cole, Abigail J. Washington, Adam Ephraim, David E. Avigan, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2659.
https://doi.org/10.1182/blood.V130.Suppl_1.2659.2659
Published: 2017