1-19 of 19
Callum M Sloss
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Pediatric Preclinical Testing Consortium Evaluation of the Anti-CD123 Antibody-Drug Conjugate, IMGN632, Against Patient-Derived Xenograft Models of Pediatric Acute Lymphoblastic Leukemia

Richard B Lock, Kathryn Evans, Joanna Randall, Stephen W Erickson, Eric J Earley, Steven Neuhauser, Tim Stearns, Vivek Philip, Beverly A Teicher, Krystal Watkins, Callum M Sloss, Patrick A Zweidler-McKay, Malcolm A Smith
Journal: Blood
Blood (2022) 140 (Supplement 1): 8983–8984.
https://doi.org/10.1182/blood-2022-159867
Published: 2022
Journal Articles

Broad Activity for the Pivekimab Sunirine (PVEK, IMGN632), Azacitidine, and Venetoclax Triplet in High-Risk Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML)

Naval Daver, Pau Montesinos, Ahmed Aribi, Giovanni Marconi, Jessica K. Altman, Eunice S. Wang, Gail J. Roboz, Patrick W. Burke, Gianluca Gaidano, Roland B. Walter, Xavier Thomas, Deepa Jeyakumar, Daniel J. DeAngelo, Harry P. Erba, Elisabetta Todisco, Kebede H. Begna, Anjali Advani, Lauris Gastaud, Adolfo De La Fuente, Antonio Curti, Lourdes M. Mendez, Paresh Vyas, Nicolas Boissel, Norbert Vey, Christian Recher, Thomas Longval, Uwe Platzbecker, Silke Kapp-Schwoerer, Christoph Schliemann, Marina Konopleva, Laura Torres, David A. Sallman, Guido Marcucci, Naveen Pemmaraju, Giovanni Martinelli, Hagop Kantarjian, Callum M Sloss, Kara E Malcolm, Patrick A Zweidler-McKay, Kendra Sweet
Journal: Blood
Blood (2022) 140 (Supplement 1): 145–149.
https://doi.org/10.1182/blood-2022-158030
Published: 2022
Journal Articles

Safety and Efficacy from a Phase 1b/2 Study of IMGN632 in Combination with Azacitidine and Venetoclax for Patients with CD123-Positive Acute Myeloid Leukemia

Naval Daver, Ahmed Aribi, Pau Montesinos, Gail J. Roboz, Eunice S. Wang, Roland B. Walter, Deepa Jeyakumar, Daniel J. DeAngelo, Harry P. Erba, Anjali Advani, Patrick W. Burke, Giovanni Martinelli, Lauris Gastaud, Xavier Thomas, Jessica K. Altman, Lourdes M. Mendez, Adolfo de la Fuente, Elisabetta Todisco, Gianluca Gaidano, Antonio Curti, Nicolas Boissel, Christian Recher, Christoph Schliemann, Marina Konopleva, David A. Sallman, Laura Torres, Guido Marcucci, Hagop Kantarjian, Callum M Sloss, Kara E Malcolm, Patrick A Zweidler-McKay, Kendra Sweet
Journal: Blood
Blood (2021) 138 (Supplement 1): 372.
https://doi.org/10.1182/blood-2021-146503
Published: 2021
Journal Articles

Experience with IMGN632, a Novel CD123-Targeting Antibody-Drug Conjugate (ADC), in Frontline Patients with Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Naveen Pemmaraju, Giovanni Martinelli, Elisabetta Todisco, Andrew A. Lane, Evelyn Acuña-Cruz, Eric Deconinck, Eunice S. Wang, Kendra Sweet, David A Rizzieri, Giovanni Marconi, Luca Mazzarella, Daniel J. DeAngelo, Pau Montesinos, Federica Gigli, Harry P. Erba, Marina Konopleva, Hagop Kantarjian, Roland B. Walter, Ahmed Aribi, Delphine Lebon, Moshe Y. Levy, Callum M Sloss, Kara E Malcolm, Patrick A Zweidler-McKay, Naval Daver
Journal: Blood
Blood (2021) 138 (Supplement 1): 1284.
https://doi.org/10.1182/blood-2021-146666
Published: 2021
Journal Articles

A Phase 1b/2 Study of the CD123-Targeting Antibody-Drug Conjugate IMGN632 As Monotherapy or in Combination with Venetoclax and Azacitidine for Patients with CD123-Positive Acute Myeloid Leukemia

Naval Daver, Ahmed Aribi, Pau Montesinos, Gail J. Roboz, Eunice S. Wang, Roland B. Walter, Deepa Jeyakumar, Daniel J. DeAngelo, Harry P. Erba, Anjali Advani, Patrick W. Burke, Giovanni Martinelli, Lauris Gastaud, Xavier Thomas, Jessica K. Altman, Lourdes M. Mendez, Adolfo de la Fuente, Elisabetta Todisco, Gianluca Gaidano, Antonio Curti, Nicolas Boissel, Christian Recher, Christoph Schliemann, Callum M Sloss, Jiuzhou Wang, Kara E Malcolm, Patrick A Zweidler-McKay, Kendra Sweet
Journal: Blood
Blood (2021) 138 (Supplement 1): 4440.
https://doi.org/10.1182/blood-2021-146585
Published: 2021
Journal Articles

A Study of IMGN632, a Novel CD123-Targeting Antibody-Drug Conjugate, for Patients with Frontline and Relapsed/Refractory Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Naveen Pemmaraju, Giovanni Marconi, Elisabetta Todisco, Pau Montesinos, Andrew A. Lane, Kendra Sweet, Eunice S. Wang, Eric Deconinck, David A Rizzieri, Roland B. Walter, Ahmed Aribi, Delphine Lebon, Moshe Y. Levy, Luca Mazzarella, Giovanni Martinelli, Federica Gigli, Harry P. Erba, Evelyn Acuña-Cruz, Marina Konopleva, Hagop Kantarjian, Callum M Sloss, Jiuzhou Wang, Kara E Malcolm, Patrick A Zweidler-McKay, Daniel J. DeAngelo, Naval Daver
Journal: Blood
Blood (2021) 138 (Supplement 1): 4429.
https://doi.org/10.1182/blood-2021-146681
Published: 2021
Journal Articles

Clinical Profile of IMGN632, a Novel CD123-Targeting Antibody-Drug Conjugate (ADC), in Patients with Relapsed/Refractory (R/R) Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Naveen Pemmaraju, MD, Giovanni Martinelli, MD, Elisabetta Todisco, MDPhD, Andrew A Lane, MD PhD, Evelyn Acuña-Cruz, MD, Eric Deconinck, MDPhD, Eunice S. Wang, MD, Kendra L. Sweet, MD MS, David A Rizzieri, MD, Luca Mazzarella, MDPhD, Daniel J. DeAngelo, MD PhD, Pau Montesinos, MD PhD, Corrado Tarella, Harry P. Erba, MD PhD, Marina Konopleva, MD PhD, Hagop M. Kantarjian, MD, Callum M Sloss, PhD, Kara E Malcolm, RN, Patrick A Zweidler-McKay, MDPhD, Naval Daver, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–13.
https://doi.org/10.1182/blood-2020-139903
Published: 2020
Journal Articles

Combining IMGN632, a Novel CD123-Targeting Antibody Drug Conjugate with Azacitidine and Venetoclax Facilitates Apoptosis in Vitro and Prolongs Survival In Vivo in AML Models

Vinitha Mary Kuruvilla, MSc, Qi Zhang, PhD, Naval Daver, MD, Krystal Watkins, Callum M Sloss, PhD, Patrick A Zweidler-McKay, MDPhD, Angela Romanelli, PhD, Marina Konopleva, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 32–33.
https://doi.org/10.1182/blood-2020-136791
Published: 2020
Journal Articles

A Phase 1b/2 Study of IMGN632, a CD123-Targeting Antibody-Drug Conjugate (ADC), As Monotherapy or in Combination with Venetoclax and/or Azacitidine for Patients with CD123-Positive Acute Myeloid Leukemia

Naval Daver, MD, Kendra L. Sweet, MD MS, Pau Montesinos, MD PhD, Eunice S. Wang, MD, Ahmed Aribi, MD, Daniel J. DeAngelo, MD PhD, Harry P Erba, MDPhD, Giovanni Martinelli, MD, Roland P Walter, MDPhD, Jessica K Altman, MD, Anjali S Advani, MD, Antonio Curti, MDPhD, Callum M Sloss, PhD, Kara E Malcolm, RN, Patrick A Zweidler-McKay, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 50–51.
https://doi.org/10.1182/blood-2020-139884
Published: 2020
Journal Articles

A Phase 1b/2 Study of the CD123-Targeting Antibody-Drug Conjugate IMGN632 As Monotherapy or in Combination with Venetoclax and/or Azacitidine for Patients with CD123-Positive Acute Myeloid Leukemia

Naval G. Daver, MD, Harry P. Erba, MD PhD, Nikolaos Papadantonakis, MDPhDMSc, Daniel J. DeAngelo, MD, Eunice S. Wang, MD, Marina Y Konopleva, MD PhD, Callum M. Sloss, PhD, Jiuzhou Wang, PhD, Kara E. Malcolm, RN, Patrick A. Zweidler-McKay, MD PhD, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2601.
https://doi.org/10.1182/blood-2019-128501
Published: 2019
Journal Articles

Clinical Profile of IMGN632, a Novel CD123-Targeting Antibody-Drug Conjugate (ADC), in Patients with Relapsed/Refractory (R/R) Acute Myeloid Leukemia (AML) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

Naval G. Daver, MD, Pau Montesinos, MD PhD, Daniel J. DeAngelo, MD, Eunice S. Wang, MD, Nikolaos Papadantonakis, MDPhDMSc, Eric Deconinck, MD PhD, Harry P. Erba, MD PhD, Naveen Pemmaraju, MD, Andrew A. Lane, MD PhD, David A. Rizzieri, MD, Kendra L. Sweet, MD, Giovanni Martinelli, Corrado Tarella, MD, Elisabetta Todisco, MD PhD, Marina Y Konopleva, MD PhD, Callum M. Sloss, PhD, Kerry Culm-Merdek, PhD, Patrick A. Zweidler-McKay, MD PhD, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 734.
https://doi.org/10.1182/blood-2019-128648
Published: 2019
Journal Articles

IMGN632, a CD123-Alkylating ADC Bearing a DNA-Alkylating IGN Payload, Combines Effectively with Azacitidine and Venetoclax In Vivo , Prolonging Survival in Preclinical Models of Human Acute Myeloid Leukemia (AML)

Vinitha Mary Kuruvilla, MSc, Rebecca McCarthy, Qi Zhang, PhD, Callum M. Sloss, PhD, Patrick A. Zweidler-McKay, MD PhD, Angela Romanelli, PhD, Sharlene Adams, PhD, Marina Y Konopleva, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1375.
https://doi.org/10.1182/blood-2019-124963
Published: 2019
Journal Articles

A Phase I, First-in-Human Study Evaluating the Safety and Preliminary Antileukemia Activity of IMGN632, a Novel CD123-Targeting Antibody-Drug Conjugate, in Patients with Relapsed/Refractory Acute Myeloid Leukemia and Other CD123-Positive Hematologic Malignancies

Naval G. Daver, MD, Harry P. Erba, MDPhD, Nikolaos Papadantonakis, MDPhDMSc, Daniel J. DeAngelo, MD, Eunice S. Wang, MD, Marina Y. Konopleva, MD PhD, Callum M. Sloss, PhD, Kerry Culm-Merdek, Patrick A. Zweidler-McKay, MD PhD, Hagop M. Kantarjian, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 27.
https://doi.org/10.1182/blood-2018-99-112955
Published: 2018
Journal Articles

Maturing Clinical Profile of IMGN779, a Next-Generation CD33-Targeting Antibody-Drug Conjugate, in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Jorge E. Cortes, MD, Daniel J. DeAngelo, MD, Harry P. Erba, MDPhD, Elie Traer, MD PhD, Nikolaos Papadantonakis, MDPhDMSc, Cecilia Arana-Yi, MD, William Blum, MD, Callum M. Sloss, PhD, Kerry Culm-Merdek, Patrick A. Zweidler-McKay, MD PhD, Eunice S. Wang, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 26.
https://doi.org/10.1182/blood-2018-99-112891
Published: 2018
Journal Articles

Synergistic Anti-Leukemic Activity of PARP Inhibition Combined with IMGN632, an Anti-CD123 Antibody-Drug Conjugate in Acute Myeloid Leukemia Models

Claire Fritz, Scott M. Portwood, MS, MBA, Julie Adams, BS, Tara Cronin, BA, Linda Lutgen-Dunckley, Brandon L Martens, BS, Callum M. Sloss, PhD, Krystal Watkins, Yelena Kovtun, PhD, Sharlene Adams, PhD, Eunice S. Wang, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2647.
https://doi.org/10.1182/blood-2018-99-117214
Published: 2018
Journal Articles

IMGN779, a Next-Generation CD33-Targeting Antibody-Drug Conjugate (ADC) Demonstrates Initial Antileukemia Activity in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Jorge E. Cortes, MD, Elie Traer, MD PhD, Eunice S. Wang, MD, Harry P. Erba, MD PhD, William Blum, MD, Cecilia Arana-Yi, MD, Callum M. Sloss, Kerry Culm-Merdek, Jeanette Towles, Patrick A. Zweidler-McKay, MDPhD, Daniel J. DeAngelo, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1312.
https://doi.org/10.1182/blood.V130.Suppl_1.1312.1312
Published: 2017
Journal Articles

IMGN779, a Next Generation CD33-Targeting ADC, Combines Effectively with Cytarabine in Acute Myeloid Leukemia (AML) Preclinical Models, Resulting in Increased DNA Damage Response, Cell Cycle Arrest and Apoptosis In Vitro and Prolonged Survival In Vivo

Sharlene Adams, Meghan Kelly, Rebecca McCarthy, Alan Wilhelm, Krystal Watkins, Leanne Lanieri, Callum M. Sloss, Angela Romanelli
Journal: Blood
Blood (2017) 130 (Supplement 1): 1357.
https://doi.org/10.1182/blood.V130.Suppl_1.1357.1357
Published: 2017
Journal Articles

Coltuximab Ravtansine (SAR3419) Demonstrates Enhanced Activity in Combination with Bendamustine, Gemcitabine and Novel Targeted Agents Such As PI3K Inhibitors in Pre-Clinical Models of Relapsed and/or Refractory Non-Hodgkins Lymphoma (NHL)

Callum M Sloss, PhD, Katie O'Callaghan, PhD, Jutta Deckert, PhD, Jenny Tsui, BS, Leanne Lanieri, BS, Angela Romanelli, PhD
Journal: Blood
Blood (2015) 126 (23): 5125.
https://doi.org/10.1182/blood.V126.23.5125.5125
Published: 2015
Journal Articles

IMGN529, a Novel Antibody-Drug Conjugate (ADC) Targeting CD37 Shows Synergistic Activity with Rituximab in Non-Hodgkin Lymphoma (NHL) Models

Jutta Deckert, PhD, Callum M Sloss, PhD, Katie O'Callaghan, PhD, Jenny Tsui, BS, Nemisha Dawra, BS, Yong Yi, MD, Jennifer A Coccia, BS, Leanne Lanieri, BS, Sharon Chicklas, BS, Angela Romanelli, PhD
Journal: Blood
Blood (2015) 126 (23): 1548.
https://doi.org/10.1182/blood.V126.23.1548.1548
Published: 2015