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Emmanuelle Clappier
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Journal Articles

Inflammatory Waldenström Macroglobulinemia is associated with clonal hematopoiesis: a multicentric cohort

Pierre-Edouard Debureaux, Stéphanie Poulain, Stephanie Harel, Marie Passet, Marie Templé, Chloe Friedrich, Nathalie Forgeard, Dikelele Elessa, William Plas, Laureen Chat, Gregory Lazarian, Lise Willems, Bruno Royer, Alexis Talbot, Tristan Vaugeois, Dr., Floriane Theves, Alexandre Terré, Anne C. Brignier, Marion Malphettes, Daphné Krzisch, Laurent Frenzel, Frédéric Davi, Clotilde Bravetti, Florence Nguyen-Khac, Jehan Dupuis, Wendy Cuccuini, Didier Bouscary, Olivier Hermine, Damien Roos-Weil, Olivier Kosmider, Emmanuelle Clappier, Marion Espéli, Karl Balabanian, Bertrand Arnulf
Journal: Blood
Blood blood.2024025738.
https://doi.org/10.1182/blood.2024025738
Published: 2024
Includes: Supplemental data
Journal Articles

Enasidenib (ENA) Monotherapy in Patients with IDH2 mutated Myelodysplastic Syndrome (MDS), the Ideal Phase 2 Study By the GFM and Emsco Groups

Marie Sebert, Sylvie Chevret, Sophie Dimicoli-Salazar, Thomas Cluzeau, Odile Rauzy, Aspasia Stamatoulas Bastard, Kamel Laribi, Gaelle Fossard, Sylvain Thépot, Silke Gloaguen, Kristell Desseaux, Norbert Vey, Pierre Peterlin, Anne-Laure Taksin, Caroline Lejeune, Sophie Park, Anne Banos, Aristoteles Giagounidis, Emmanuel Gyan, Mario Ojeda-Uribe, Stefanie Groepper, Fatiha Chermat, Emmanuelle Clappier, Uwe Platzbecker, Pierre Fenaux, Lionel Ades
Journal: Blood
Blood (2024) 144 (Supplement 1): 1839.
https://doi.org/10.1182/blood-2024-201317
Published: 2024
Journal Articles

Characteristics and Outcome Determinants in Children, Adolescents and Young Adults Who Failed Tisagenlecleucel for B-Cell Acute Lymphoblastic Leukemia

Nicolas Lecornec, Florence Rabian, Marie-Emilie Dourthe, Florian Chevillon, Karima Yakouben, Delphine Chaillou, Sophie Caillat-Zucman, Alexis Cuffel, Emmanuelle Lesprit, Anne Arnould, Jérome Naudin, Julie Roupret-Serzec, Nathalie Parquet, Anne Brignier, Valerie Guerin-El Khourouj, Elodie Lainey, Aurélie Caye-Eude, Chloe Arfeuille, Emmanuelle Clappier, Rathana Kim, Stéphanie Mathis, Marie-Laure Chaix, Elie Azoulay, Jean-Hugues Dalle, Isabelle Madelaine, Jerome Larghero, André Baruchel, Nicolas Boissel
Journal: Blood
Blood (2024) 144 (Supplement 1): 1433.
https://doi.org/10.1182/blood-2024-209895
Published: 2024
Journal Articles

Prognostic Significance of Monocytic-like Phenotype in AML Patients Treated with Venetoclax and Azacytidine

Lin Pierre Zhao, Typhaine Dumas-Rivero, Lauren Barette, Lorea Aguinaga, Arij Cheffai, Pierre Lemaire, Stéphanie Mathis, Clémentine Chauvel, Reinaldo Dal Bello, Emmanuelle Clappier, Matthieu Duchmann, Pierre Fenaux, Marie Sebert, Lionel Ades, Raphael Itzykson
Journal: Blood
Blood (2024) 144 (Supplement 1): 4316.
https://doi.org/10.1182/blood-2024-203353
Published: 2024
Journal Articles

Inflammatory Waldenström Macroglobulinemia Is Associated with Clonal Hematopoiesis: A Multicentric Cohort

Pierre-Edouard Debureaux, Stephanie Poulain, Marie Passet, Marie Temple, Chloé Friedrich, Nathalie Forgeard, Dikelele Elessa, William Plas, Laureen Chat, Gregory Lazarian, Lise Willems, Bruno Royer, Alexis Talbot, Tristan Vaugeois, Floriane Theves, Alexandre Terre, Anne Brignier, Marion Malphettes, Daphne Krzisch, Laurent Frenzel, Frederic Davi, Clothilde Bravetti, Florence Nguyen-Khac, Jehan Dupuis, Wendy Cuccuini, Didier Bouscary, Olivier Hermine, Damien Roos-Weil, Olivier Kosmider, Emmanuelle Clappier, Marion Espeli, Karl Balabanian, Bertrand Arnulf
Journal: Blood
Blood (2024) 144 (Supplement 1): 4343.
https://doi.org/10.1182/blood-2024-193883
Published: 2024
Journal Articles

The Presence of SH2B3 mutations Identifies a Distinct Subtype of Myelodysplastic Neoplasms

Maria Julia Montoro, Pamela Acha, Manja Meggendorfer, Najla H Al Ali, Víctor Navarro, Sherry Pierce, Carlos Bravo-Perez, Marie Adeline Migeon, Mestre Julia, Klaus H Metzeler, Michael Wulfert, Andres Jerez, Marina Díaz-Beyá, Beate Betz, Emmanuelle Clappier, Mar Tormo, Helena Pomares, Mónica Del Rey, Silvia Saumell, Laura Barbero, María Eugenia Rivero, Maria Diez-Campelo, David Sallman, Teresa Ezponda, Weina Chen, Zhuoer Xie, Francesc Bosch, Ulrich Germing, Uwe Platzbecker, Francesc Sole, Pierre Fenaux, Jaroslaw Maciejewski, Guillermo Garcia-Manero, Rami S. Komrokji, Torsten Haferlach, David Valcarcel
Journal: Blood
Blood (2024) 144 (Supplement 1): 3214.
https://doi.org/10.1182/blood-2024-194488
Published: 2024
Journal Articles

Determinants of Isolated CNS Relapse in Adults with Philadelphia-Negative Acute Lymphoblastic Leukemia. from Graall-2005 to -2014 Trials

Nicolas Boissel, Emilie Lemasle, Sylvain Chantepie, Thibaut Leguay, Corentin Orvain, Françoise Huguet, Yosr Hicheri, Nathalie Dhédin, Patrice Chevallier, Marie Balsat, Sébastien Maury, Hunault-Berger Mathilde, Karin Bilger, Eolia Brissot, Sebastian Wittnebel, Julie Guerder, Sarah Bonnet, Pascal Turlure, Anne Huynh, Claire Bories, Michael Gregor, Natacha Mauz, Ahmad Aljijakli, Carlos Graux, Yves Chalandon, Norbert Ifrah, Vahid Asnafi, Emmanuelle Clappier, Véronique Lheritier, Hervé Dombret
Journal: Blood
Blood (2024) 144 (Supplement 1): 731.
https://doi.org/10.1182/blood-2024-198614
Published: 2024
Journal Articles

Nilotinib with or without cytarabine for Philadelphia-positive acute lymphoblastic leukemia

Clinical Trials & Observations
Yves Chalandon, Philippe Rousselot, Sylvie Chevret, Jean-Michel Cayuela, Rathana Kim, Françoise Huguet, Patrice Chevallier, Carlos Graux, Anne Thiebaut-Bertrand, Sylvain Chantepie, Xavier Thomas, Laure Vincent, Céline Berthon, Yosr Hicheri, Emmanuel Raffoux, Martine Escoffre-Barbe, Isabelle Plantier, Magalie Joris, Pascal Turlure, Florence Pasquier, Amine Belhabri, Gabrielle Roth Guepin, Sabine Blum, Michael Gregor, Marina Lafage-Pochitaloff, Julie Quessada, Véronique Lhéritier, Emmanuelle Clappier, Nicolas Boissel, Hervé Dombret
Journal: Blood
Blood (2024) 143 (23): 2363–2372.
https://doi.org/10.1182/blood.2023023502
Published: 2024
Includes: Supplemental data
Journal Articles

Uncovering new layers of Ph + ALL biology

Rathana Kim, Emmanuelle Clappier
Journal: Blood
Blood (2024) 143 (14): 1322–1323.
https://doi.org/10.1182/blood.2023023583
Published: 2024
Journal Articles

Genetic alterations and MRD refine risk assessment for KMT2A -rearranged B-cell precursor ALL in adults: a GRAALL study

Rathana Kim, Hugo Bergugnat, Cédric Pastoret, Florence Pasquier, Emmanuel Raffoux, Lise Larcher, Marie Passet, Nathalie Grardel, Eric Delabesse, Susanne Kubetzko, Aurélie Caye-Eude, Claus Meyer, Rolf Marschalek, Marine Lafage-Pochitaloff, Anne Thiebaut-Bertrand, Marie Balsat, Martine Escoffre-Barbe, Sabine Blum, Michael Baumann, Anne Banos, Nicole Straetmans, Maria-Pilar Gallego-Hernanz, Yves Chalandon, Carlos Graux, Jean Soulier, Thibaut Leguay, Mathilde Hunault, Françoise Huguet, Véronique Lhéritier, Hervé Dombret, Nicolas Boissel, Emmanuelle Clappier
Journal: Blood
Blood (2023) 142 (21): 1806–1817.
https://doi.org/10.1182/blood.2023021501
Published: 2023
Includes: Supplemental data
Journal Articles

Distinct Pattern of ABL1 Genomic Breakpoints in Chronic Myeloid Leukemia and BCR::ABL1-Positive Acute Lymphoblastic Leukemia: Analysis of 884 Patients with Minor and Major BCR::ABL1 Fusion

Lenka Hovorkova, Lucie Winkowska, Justina Krotka, Manuela Krumbholz, Claus Meyer, Rosemary Sutton, Michelle Henderson, Emmanuelle Clappier, Sabina Chiaretti, Lucie Sramkova, Jan Stary, Adela Benesova, Katerina Machova Polakova, Rolf Marschalek, Markus Metzler, Giovanni Cazzaniga, Gunnar Cario, Jan Trka, Marketa Zaliova, Jan Zuna
Journal: Blood
Blood (2023) 142 (Supplement 1): 1605.
https://doi.org/10.1182/blood-2023-180355
Published: 2023
Journal Articles

The Splicing-Associated Network PAK1-Clk-SRRM1 Is a Critical Vulnerability to Overcome Chemoresistance in Acute Myeloid Leukemia

Camille Vaganay, Frank Ling, Lois M. Kelly, Duong Ho Nhat, Antoine Forget, Paul-Arthur Meslin, Hélène Pasquer, Rathana Kim, Marie Passet, Sofiane Fodil, Tony Huynh, Angela H Su, Christopher F Bassil, Matthieu Duchmann, Gabriela Alexe, Gael Fortin, Carine Legrand, Khansa Saadallah, Christopher Delaney, Kim Pacchiardi, Anja Kocijancic, Lisa Aziez, Nina Fenouille, Marie Sebert, Lionel Ades, Emmanuel Raffoux, Emmanuelle Clappier, Lina Benajiba, Kimberly Stegmaier, Kris C. Wood, Raphael Itzykson, Camille Lobry, Alexandre Puissant
Journal: Blood
Blood (2023) 142 (Supplement 1): 409.
https://doi.org/10.1182/blood-2023-186264
Published: 2023
Journal Articles

Exploring the Heterogeneity of Response to Blinatumomab in High-Risk Philadelphia-Negative B-Cell Precursor Acute Lymphoblastic Leukemia: An Analysis from the QUEST Sub-Study of the Graall-2014/B Trial

Nicolas Boissel, Francoise Huguet, Thibaut Leguay, Mathilde Hunault, Rathana KIM, Yosr Hicheri, Marie Passet, Patrice Chevallier, Marie Balsat, Sebastien Maury, Anne Thiebaut, Florence Van Obbergh, Thomas Cluzeau, Martine Escoffre Barbe, Nicole Straetmans, Johanna Konopacki, Amine Belhabri, Alban Villate, Florence Pasquier, Didier Bouscary, Thorsten Braun, Sabine Blum, Victoria Cacheux, Caroline Bonmati, Sebastian Wittnebel, Véronique Lhéritier, Norbert Ifrah, Carlos Graux, Yves Chalandon, Emmanuelle Clappier, Herve Dombret
Journal: Blood
Blood (2023) 142 (Supplement 1): 4349.
https://doi.org/10.1182/blood-2023-177847
Published: 2023
Journal Articles

Somatic Mutations and DNA Hypermethylation at Enhancers and Promoters Identify Distinct Subtypes within Lower-Risk Myelodysplastic Syndromes

David Rombaut, Tobias Tekath, Sarah Sandmann, Simon Crouch, Aniek O. de Graaf, Olivier Kosmider, Magnus Tobiasson, Andreas Lennartsson, Bert A. Van der Reijden, Sophie Park, Maud D'Aveni, Bohrane Slama, Emmanuelle Clappier, Pierre Fenaux, Lionel Ades, Arjan A. van de Loosdrecht, Saskia MC Langemeijer, Argiris S. Symeonidis, Jaroslav Čermák, Claude Preudhomme, Aleksandar Savic, Ulrich Germing, Reinhard Stauder, David T. Bowen, Corine J. Van Marrewijk, Elsa Bernard, Alexandra Smith, Daniel Painter, Theo J.M. de Witte, Eva Hellstrom Lindberg, Julian Varghese, Martin Dugas, Joost H.A. Martens, Luca Malcovati, Joop H. Jansen, Michaela Fontenay
Journal: Blood
Blood (2023) 142 (Supplement 1): 4587.
https://doi.org/10.1182/blood-2023-180071
Published: 2023
Journal Articles

Low Disease Burden Pre-CAR-T Cell Therapy for Children and AYA with B-ALL Is Associated with an Impaired Outcome When Obtained through Intensification of the Bridging Therapy

Nicolas Lecornec, Marie-Emilie Dourthe, Florence Rabian, Karima Yakouben, Florian Chevillon, Delphine Chaillou, Sophie Caillat-Zucman, Alexis Cuffel, Emmanuelle Lesprit, Anne Arnould, Jérome Naudin, Julie Roupret-Serzec, Nathalie Parquet, Anne Brignier, Valerie Guerin-El Khourouj, Elodie Lainey, Aurélie Caye-Eude, Chloe Arfeuille, Emmanuelle Clappier, Stéphanie Mathis, Marie-Laure Chaix, Elie Azoulay, Jean-Hugues Dalle, Isabelle Madelaine, Jerome Larghero, Nicolas Boissel, André Baruchel
Journal: Blood
Blood (2023) 142 (Supplement 1): 2134.
https://doi.org/10.1182/blood-2023-175045
Published: 2023
Journal Articles

IPSS-M in myelodysplastic neoplasms arising from aplastic anemia and paroxysmal nocturnal hemoglobinuria

Carmelo Gurnari, Pedro Henrique Prata, Luiz Fernando B. Catto, Arda Durmaz, Lise Larcher, Marie Sebert, Vincent Allain, Tariq Kewan, Simona Pagliuca, Andre L. Pinto, Mariana C. B. Inacio, Lucie Hernandez, Nathalie Dhedin, Sophie Caillat-Zucman, Emmanuelle Clappier, Flore Sicre de Fontbrune, Maria Teresa Voso, Valeria Visconte, Régis Peffault de Latour, Jean Soulier, Gérard Socié, Rodrigo T. Calado, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2023) 141 (25): 3122–3125.
https://doi.org/10.1182/blood.2023020108
Published: 2023
Includes: Supplemental data
Journal Articles

Molecular International Prognostic Scoring System (IPSS-M) in Myelodysplastic Syndromes Arising from Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria

Carmelo Gurnari, Pedro H. Prata, Luiz Fernando Bazzo Catto, Arda Durmaz, Lise Larcher, Marie Sebert, Vincent Allain, Tariq Kewan, Simona Pagliuca, Andre Luiz Pinto, Mariana C. B. Inacio, Lucie Hernandez, Nathalie Dhedin, Sophie Caillat-Zucman, Emmanuelle Clappier, Flore Sicre de Fontbrune, Maria Teresa Voso, Valeria Visconte, Régis Peffault de Latour, Jean Soulier, Gérard Socié, Rodrigo T. Calado, Jaroslaw P. Maciejewski
Journal: Blood
Blood (2022) 140 (Supplement 1): 5788–5789.
https://doi.org/10.1182/blood-2022-160458
Published: 2022
Journal Articles

Characteristics of Germline CHEK2 Mutated Patients in a Large Cohort of 2322 Myeloid Malignancies

Lucie Freiman, Lise Larcher, Giulia Tueur, Nadia Vasquez, Mélanie Da Costa, Emmanuel Raffoux, Lionel Ades, Pierre Fenaux, Jean Soulier, Emmanuelle Clappier, Raphael Itzykson
Journal: Blood
Blood (2022) 140 (Supplement 1): 4082–4083.
https://doi.org/10.1182/blood-2022-158799
Published: 2022
Journal Articles

Blinatumomab during Consolidation in High-Risk Philadelphia Chromosome (Ph)-Negative B-Cell Precursor (BCP) Acute Lymphoblastic Leukemia (ALL) Adult Patients: A Two-Cohort Comparison within the Graall-2014/B Study

Nicolas Boissel, Francoise Huguet, Thibaut Leguay, Mathilde Hunault, Rathana KIM, Yosr Hicheri, Patrice Chevallier, Marie Balsat, Sébastien Maury, Anne Thiebaut-Bertrand, Florence Van Obbergh, Thomas Cluzeau, Martine Escoffre-Barbe, Nicole Straetmans, Johanna Konopacki, Amine Belhabri, Alban Villate, Florence Pasquier, Ioana Vaida, Laurence Sanhes, Magda Alexis, Cedric Pastoret, Mathlide Lamarque, Laure Farnault, Nathalie Grardel, Celine Berthon, Eric Delabesse, Veronique Lheritier, Norbert Ifrah, Carlos Graux, Yves Chalandon, Emmanuelle Clappier, Herve Dombret
Journal: Blood
Blood (2022) 140 (Supplement 1): 507–509.
https://doi.org/10.1182/blood-2022-159397
Published: 2022
Journal Articles

Fractionated Inotuzumab Ozogamicin Combined with Low-Intensity Chemotherapy in Older Patients with Newly Diagnosed CD22+ Philadelphia Chromosome (Ph)-Negative B-Cell Precursor (BCP) Acute Lymphoblastic Leukemia (ALL): Results of the EWALL-INO Study

Patrice Chevallier, Thibault Leguay, Rathana KIM, Marc Delord, Michael Doubek, Francoise Huguet, Aurelie Cabannes-Hamy, Ulla Wartiovaara-Kautto, Colombe Saillard, Emmanuel Raffoux, Thomas Cluzeau, Stephane Lepretre, Marie Balsat, Anna Berceanu, Nicolas Boissel, Claude Gardin, Emmanuelle Clappier, Herve Dombret, Philippe Rousselot
Journal: Blood
Blood (2022) 140 (Supplement 1): 6114–6116.
https://doi.org/10.1182/blood-2022-166035
Published: 2022