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Martine Escoffre Barbe
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Journal Articles

18-Months Follow-up of the Trial of Imatinib after Ponatinib Induction (TIPI) in the Front-Line Treatment of Chronic Phase (CP) Chronic Myeloid Leukemia (CML) Setting

Franck E. Nicolini, Aude Charbonnier, Martine Escoffre-Barbe, Eric Jourdan, Gabrielle Roth-Guepin, Marc G. Berger, Shanti Ame, Marion Simonet, Hyacinthe A Johnson-Ansah, Viviane Dubruille, Amandine Charbonnier, Philippe Rousselot, Corentin Orvain, Bertrand Joly, Jean-Christophe Ianotto, Emilie Cayssials, Mathieu Meunier, Anne Parry, Valerie Coiteux, Laurence Legros, Hacene Zerazhi, Gabriel Etienne, Philippe Quittet, Ollivier Legrand, Amelie Penot, Lydia Roy, Charlotte Doublet, Stéphane Morisset, Romaine Mayet, Gwenaëlle Garin, Stéphanie Dulucq, Françoise Huguet
Journal: Blood
Blood (2024) 144 (Supplement 1): 478.
https://doi.org/10.1182/blood-2024-198903
Published: 2024
Journal Articles

Switch of Asparaginase Formulation Based on Antibody Monitoring in Adults with Philadelphia-Negative Adult Lymphoblastic Leukemia. Results of the Graall-2014 Trial

Marie Balsat, Corentin Orvain, Jean-François Benoist, Nicolas De Roux, Thibaut Leguay, Françoise Huguet, Patrice Chevallier, Cendrine Josson, Christine Bain-Wendlinger, Yosr Hicheri, Anne Thiebaut, Martine Escoffre-Barbe, Thomas Cluzeau, Florence Pasquier, Ana Berceanu, Florence Van Obbergh, Jamilé Frayfer, Gaëlle Guillerm, Victoria Cacheux, Isabelle Plantier, Laurence Sanhes, Chantal Himberlin, Jacques Vargaftig, Sabine Tricot, Yves Chalandon, Carlos Graux, Véronique Lheritier, Hervé Dombret, Hunault-Berger Mathilde, Nicolas Boissel
Journal: Blood
Blood (2024) 144 (Supplement 1): 1434.
https://doi.org/10.1182/blood-2024-199110
Published: 2024
Journal Articles

Nilotinib with or without cytarabine for Philadelphia-positive acute lymphoblastic leukemia

Clinical Trials & Observations
Yves Chalandon, Philippe Rousselot, Sylvie Chevret, Jean-Michel Cayuela, Rathana Kim, Françoise Huguet, Patrice Chevallier, Carlos Graux, Anne Thiebaut-Bertrand, Sylvain Chantepie, Xavier Thomas, Laure Vincent, Céline Berthon, Yosr Hicheri, Emmanuel Raffoux, Martine Escoffre-Barbe, Isabelle Plantier, Magalie Joris, Pascal Turlure, Florence Pasquier, Amine Belhabri, Gabrielle Roth Guepin, Sabine Blum, Michael Gregor, Marina Lafage-Pochitaloff, Julie Quessada, Véronique Lhéritier, Emmanuelle Clappier, Nicolas Boissel, Hervé Dombret
Journal: Blood
Blood (2024) 143 (23): 2363–2372.
https://doi.org/10.1182/blood.2023023502
Published: 2024
Includes: Supplemental data
Journal Articles

Genetic alterations and MRD refine risk assessment for KMT2A -rearranged B-cell precursor ALL in adults: a GRAALL study

Rathana Kim, Hugo Bergugnat, Cédric Pastoret, Florence Pasquier, Emmanuel Raffoux, Lise Larcher, Marie Passet, Nathalie Grardel, Eric Delabesse, Susanne Kubetzko, Aurélie Caye-Eude, Claus Meyer, Rolf Marschalek, Marine Lafage-Pochitaloff, Anne Thiebaut-Bertrand, Marie Balsat, Martine Escoffre-Barbe, Sabine Blum, Michael Baumann, Anne Banos, Nicole Straetmans, Maria-Pilar Gallego-Hernanz, Yves Chalandon, Carlos Graux, Jean Soulier, Thibaut Leguay, Mathilde Hunault, Françoise Huguet, Véronique Lhéritier, Hervé Dombret, Nicolas Boissel, Emmanuelle Clappier
Journal: Blood
Blood (2023) 142 (21): 1806–1817.
https://doi.org/10.1182/blood.2023021501
Published: 2023
Includes: Supplemental data
Journal Articles

Characteristics, Outcomes, Tfr Rates in Young Adults with Chronic Myeloid Leukemia in the Tyrosine Kinase Inhibitor Era: A French Observational Study

Laurence Legros, Francoise Huguet, Pascale Cony-Makhoul, Irit Touitou, Franck E. Nicolini, Delphine Rea, Marc G. Berger, Madalina Uzunov, Lydia Roy, Martine Escoffre Barbe, Agnes Guerci Bresler, Gabriel Etienne, Elisabeth Daguenet, Amelie Penot, Martine Gardembas Pain, Shanti Ame, Eric Jourdan, Hyacinthe A. Johnson-Ansah, Valerie Coiteux, Antoine Machet, Eric Lippert, Anne Vekoff, Jean Michel Karsenti, Stéphane Morisset, Francois Mahon
Journal: Blood
Blood (2023) 142 (Supplement 1): 1800.
https://doi.org/10.1182/blood-2023-173132
Published: 2023
Journal Articles

Oncogenetic-Driven Targeted Therapy for Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia : A French ALL-Target Observatory Report

Aurelie Cabannes-Hamy, Lucien Courtois, Marie Balsat, Mathieu Simonin, Françoise Huguet, Martine Escoffre-Barbe, Florence Pasquier, Caroline Bonmati, Pascal Turlure, Thomas Cluzeau, Delphine Lebon, Eve Gehlkopf, Eolia Brissot, Justine Decroocq, Patrice Chevallier, Sylvain Chantepie, Victoria Cacheux, Sebastien Maury, Safia Chebrek, Thibaut Leguay, Melody Fort, Natacha Mauz, Mathlide Lamarque, Hunault-Berger Mathilde, Stefan Wickenhauser, Jamilé Frayfer, Anne Banos, Emmanuelle Tavernier, Denis Caillot, Anne Marie Ronchetti, Celine Berthon, Etienne Lengline, Véronique Lhéritier, Hervé Dombret, Ambroise Marçais, Antoine Pinton, Guillaume P Andrieu, Nicolas Boissel, Ludovic Lhermitte, Vahid Asnafi, Philippe Rousselot
Journal: Blood
Blood (2023) 142 (Supplement 1): 518.
https://doi.org/10.1182/blood-2023-179192
Published: 2023
Journal Articles

T rial of Imatinib after Ponatinib Induction (TIPI) in the Front-Line Treatment of Chronic Phase (CP) Chronic Myeloid Leukemia (CML) Setting. Report of the First Therapeutic Sequence

Franck E. Nicolini, Aude Charbonnier, Martine Escoffre-Barbe, Eric Jourdan, Gabrielle Roth-Guepin, Marc G. Berger, Shanti Amé, Marion Simonet, Hyacinthe A. Johnson-Ansah, Viviane Dubruille, Amandine Charbonnier, Philippe Rousselot, Corentin Orvain, Bertrand Joly, Jean-Christophe Ianotto, Emilie Cayssials, Mathieu Meunier, Anne Parry, Valerie Coiteux, Laurence Legros, Hacene Zerazhi, Gabriel Etienne, Philippe Quittet, Ollivier Legrand, Amelie Penot, Lydia Roy, Ludovic Fouillet, Stéphane Morisset, Isabelle Tigaud, Romaine Mayet, Gwenaëlle Garin, Jérôme Guitton, Stéphanie Dulucq, Françoise Huguet
Journal: Blood
Blood (2023) 142 (Supplement 1): 445.
https://doi.org/10.1182/blood-2023-181571
Published: 2023
Journal Articles

Exploring the Heterogeneity of Response to Blinatumomab in High-Risk Philadelphia-Negative B-Cell Precursor Acute Lymphoblastic Leukemia: An Analysis from the QUEST Sub-Study of the Graall-2014/B Trial

Nicolas Boissel, Francoise Huguet, Thibaut Leguay, Mathilde Hunault, Rathana KIM, Yosr Hicheri, Marie Passet, Patrice Chevallier, Marie Balsat, Sebastien Maury, Anne Thiebaut, Florence Van Obbergh, Thomas Cluzeau, Martine Escoffre Barbe, Nicole Straetmans, Johanna Konopacki, Amine Belhabri, Alban Villate, Florence Pasquier, Didier Bouscary, Thorsten Braun, Sabine Blum, Victoria Cacheux, Caroline Bonmati, Sebastian Wittnebel, Véronique Lhéritier, Norbert Ifrah, Carlos Graux, Yves Chalandon, Emmanuelle Clappier, Herve Dombret
Journal: Blood
Blood (2023) 142 (Supplement 1): 4349.
https://doi.org/10.1182/blood-2023-177847
Published: 2023
Journal Articles

Frontline Consolidation with Nelarabine for Adults with High-Risk T-Cell Acute Lymphoblastic Leukemia. Results of the Graall-2014/T Atriall Phase 2 Study

Nicolas Boissel, Carlos Graux, Francoise Huguet, Florence Pasquier, Aurore Touzart, Thomas Cluzeau, Ludovic Lhermitte, Eric Delabesse, Patrice Chevallier, Mathilde Hunault, Cedric Pastoret, Sebastien Maury, Nathalie Grardel, Martine Escoffre Barbe, Pascal Turlure, Beat Schafer, Marie Balsat, Philippe Rousselot, Thibaut Leguay, Eric Jourdan, Delphine Pranger, Michael Gregor, Emilie Lemasle, Anne Marie Ronchetti, Ana Berceanu, Ingrid Lafon, Madalina Uzunov, Etienne Lengline, Norbert Ifrah, Yves Chalandon, Véronique Lhéritier, Vahid Asnafi, Herve Dombret
Journal: Blood
Blood (2023) 142 (Supplement 1): 962.
https://doi.org/10.1182/blood-2023-177696
Published: 2023
Journal Articles

Blinatumomab during Consolidation in High-Risk Philadelphia Chromosome (Ph)-Negative B-Cell Precursor (BCP) Acute Lymphoblastic Leukemia (ALL) Adult Patients: A Two-Cohort Comparison within the Graall-2014/B Study

Nicolas Boissel, Francoise Huguet, Thibaut Leguay, Mathilde Hunault, Rathana KIM, Yosr Hicheri, Patrice Chevallier, Marie Balsat, Sébastien Maury, Anne Thiebaut-Bertrand, Florence Van Obbergh, Thomas Cluzeau, Martine Escoffre-Barbe, Nicole Straetmans, Johanna Konopacki, Amine Belhabri, Alban Villate, Florence Pasquier, Ioana Vaida, Laurence Sanhes, Magda Alexis, Cedric Pastoret, Mathlide Lamarque, Laure Farnault, Nathalie Grardel, Celine Berthon, Eric Delabesse, Veronique Lheritier, Norbert Ifrah, Carlos Graux, Yves Chalandon, Emmanuelle Clappier, Herve Dombret
Journal: Blood
Blood (2022) 140 (Supplement 1): 507–509.
https://doi.org/10.1182/blood-2022-159397
Published: 2022
Journal Articles

In Adults with Ph-Negative Acute Lymphoblastic Leukemia (ALL), Age-Adapted Chemotherapy Intensity and MRD-Driven Transplant Indication Significantly Reduces Treatment-Related Mortality (TRM) and Improves Overall Survival - Results from the Graall-2014 Trial

Nicolas Boissel, Francoise Huguet, Thibaut Leguay, Hunault-Berger Mathilde, Carlos Graux, Yves Chalandon, Eric Delabesse, Yosr Hicheri, Patrice Chevallier, Marie Balsat, Cedric Pastoret, Martine Escoffre-Barbe, Florence Pasquier, Jean-Pierre Marolleau, Anne Thiebaut-Bertrand, Anne Huynh, Nathalie Dhedin, Emilie Lemasle, Caroline Bonmati, Sébastien Maury, Gaëlle Guillerm, Anna Berceanu, Urs Schanz, Thomas Cluzeau, Pascal Turlure, Philippe Rousselot, Bernard J.M. De Prijck, Nathalie Grardel, Marie C Bene, Marine Lafage, Norbert Ifrah, Veronique Lheritier, Vahid Asnafi, Emmanuelle Clappier, Herve Dombret
Journal: Blood
Blood (2022) 140 (Supplement 1): 112–114.
https://doi.org/10.1182/blood-2022-157903
Published: 2022
Journal Articles

Low Non Relapse Mortality and Good Hematological Response after Autologous Hematopoietic Stem Cell Transplantation in Multiple Myeloma Patients with Renal Insufficiency at Transplant: A Prospective Société Francaise De Greffe De Moelle-Thérapie Cellulaire Observational Study

Laurent Garderet, Hafida Ouldjeriouat, Mohamed-Amine Bekadja, Elisabeth Daguenet, Laure Vincent, Damien Roos Weil, Marguerite Vignon, Mohamad Mohty, Julie Abraham, Martine Escoffre-Barbe, Bruno Lioure, redhouane Ahmed Nacer, Denis Caillot, Clara Mariette, Lionel Karlin, Pierre Morel, Lila Gilis, Emanuelle Leray, Anaise Blouet, Nicole Raus, Marie Robin, jean Jacques Boffa, Pierre Ronco, Marie Thérèse Rubio, Jerome Lambert, Jérôme Cornillon
Journal: Blood
Blood (2022) 140 (Supplement 1): 7219–7221.
https://doi.org/10.1182/blood-2022-165913
Published: 2022
Journal Articles

Bortezomib and high-dose melphalan conditioning regimen in frontline multiple myeloma: an IFM randomized phase 3 study

Clinical Trials & Observations
Murielle Roussel, Valérie Lauwers-Cances, Margaret Macro, Xavier Leleu, Bruno Royer, Cyrille Hulin, Lionel Karlin, Aurore Perrot, Cyrille Touzeau, Marie-Lorraine Chrétien, Sophie Rigaudeau, Mamoun Dib, Emmanuelle Nicolas-Virelizier, Martine Escoffre-Barbe, Karim Belhadj, Clara Mariette, Anne-Marie Stoppa, Carla Araujo, Chantal Doyen, Jean Fontan, Brigitte Kolb, Laurent Garderet, Sabine Brechignac, Jean-Valère Malfuson, Arnaud Jaccard, Pascal Lenain, Cécile Borel, Benjamin Hebraud, Omar Benbrahim, Véronique Dorvaux, Salomon Manier, Karine Augeul-Meunier, Marie-Christiane Vekemans, Edouard Randriamalala, Driss Chaoui, Jo Caers, Carine Chaleteix, Lofti Benboubker, Laure Vincent, Sylvie Glaisner, Patricia Zunic, Borhane Slama, Jean-Richard Eveillard, Catherine Humbrecht-Kraut, Véronique Morel, Philippe Mineur, Jean-Claude Eisenmann, Hélène Demarquette, Valentine Richez, Marguerite Vignon, Denis Caillot, Thierry Facon, Philippe Moreau, Anne-Laurène Colin, Pascale Olivier, Soraya Wuilleme, Hervé Avet-Loiseau, Jill Corre, Michel Attal
Journal: Blood
Blood (2022) 139 (18): 2747–2757.
https://doi.org/10.1182/blood.2021014635
Published: 2022
Includes: Supplemental data
Journal Articles

Treatment-Free Remissions in Newly Diagnosed CP CML Patients Treated with the Combination of Nilotinib + Pegylated Interferon Alpha 2a Versus Nilotinib Alone in the National Phase III Petals Trial

Franck E. Nicolini, Gabriel Etienne, Francoise Huguet, Agnès Guerci-Bresler, Aude Charbonnier, Martine Escoffre-Barbe, Viviane Dubruille, Hyacinthe Johnson-Ansah, Laurence Legros, Valerie Coiteux, Pascale Cony-Makhoul, Pascal Lenain, Lydia Roy, Philippe Rousselot, Denis Guyotat, Jean-Christophe Ianotto, Corentin Orvain, Eric Deconinck, Denis Caillot, Pascal Turlure, Stephane Courby, Philippe Quittet, Eric Hermet, Shanti Amé, Simona Lapusan, Stephane Morisset, Francois-Xavier Mahon, Delphine Rea, Stephanie Dulucq
Journal: Blood
Blood (2021) 138 (Supplement 1): 2553.
https://doi.org/10.1182/blood-2021-146412
Published: 2021
Journal Articles

Impact of Central Nervous System Involvement in Adult Patients with Acute Lymphoblastic Leukemia Treated in a Pediatrics-Inspired Protocol - a Graall Study

Corentin Orvain, Sylvain Chantepie, Xavier Thomas, Martine Escoffre-Barbe, Francoise Huguet, Yohan Desbrosses, Gaelle Guillerm, Thibaut Leguay, Sarah Barbieux, Norbert Vey, Patrice Chevallier, Jean Valere Malfuson, Stephane Lepretre, Jean Pierre Marolleau, Hacene Zerazhi, Diana Carp, Ambroise Marçais, Maria Pilar Gallego Hernanz, Iona Vaida, Florence Pasquier, Veronique Lheritier, Norbert Ifrah, Hervé Dombret, Nicolas Boissel, Hunault-Berger Mathilde
Journal: Blood
Blood (2021) 138 (Supplement 1): 215.
https://doi.org/10.1182/blood-2021-150705
Published: 2021
Journal Articles

The Omission of High-Dose Cytarabine during Consolidation Therapy of Ph-Positive ALL Patients Treated with Nilotinib and Low-Intensity Chemotherapy Results in an Increased Risk of Relapses Despite Non-Inferior Levels of Late BCR-ABL1 MRD Response. First Results of the Randomized Graaph-2014 Study

Philippe Rousselot, Yves Chalandon, Sylvie Chevret, Jean-Michel Cayuela, Francoise Huguet, Patrice Chevallier, Carlos Graux, Anne Thiebaut-Bertrand, Sylvain Chantepie, Xavier Thomas, Laure Vincent, Celine Berthon, Norbert Vey, Emmanuel Raffoux, Martine Escoffre-Barbe, Isabelle Plantier, Jean Pierre Marolleau, Pascal Turlure, Florence Pasquier, Amine Belhabri, Gabrielle Roth Guepin, Olivier Spertini, Veronique Lheritier, Emmanuelle Clappier, Nicolas Boissel, Hervé Dombret
Journal: Blood
Blood (2021) 138 (Supplement 1): 512.
https://doi.org/10.1182/blood-2021-148843
Published: 2021
Journal Articles

Frontline Consolidation with Blinatumomab for High-Risk Philadelphia-Negative Acute Lymphoblastic Adult Patients. Early Results from the Graall-2014-QUEST Phase 2

Nicolas Boissel, Francoise Huguet, Carlos Graux, Yosr Hicheri, Patrice Chevallier, Rathana KIM, Marie Balsat, Thibaut Leguay, Mathilde Hunault, Sébastien Maury, Anne Thiebaut-Bertrand, Martine Escoffre-Barbe, Thomas Cluzeau, Alban Villate, Florence Pasquier, Laure Farnault, Florence Van Obbergh, Philippe Rousselot, Yves Chalandon, Eric Delabesse, Cedric Pastoret, Emmanuelle Clappier, Veronique Lheritier, Herve Dombret
Journal: Blood
Blood (2021) 138 (Supplement 1): 1232.
https://doi.org/10.1182/blood-2021-146163
Published: 2021
Journal Articles

Phase II Study of the Combination of Pomalidomide with Dexamethasone As Maintenance Therapy after First Relapse Treatment with PCD Followed or Not By Autologous Stem Cell Transplant in Multiple Myeloma Patients

Laurent Garderet, Frédérique Kuhnowski, Benoit Berge, Murielle Roussel, Martine Escoffre-Barbe, Ingrid Lafon, Thierry Facon, Xavier Leleu, Lionel Karlin, Aurore Perrot, Philippe Moreau, Gerald Marit, Anne-Marie Stoppa, Bruno Royer, Carine Chaleteix, Mourad Tiab, Carla Araujo, Pascal Lenain, Margaret Macro, Eric G. Voog, Lotfi Benboubker, Olivier Thierry Allangba, Eric Jourdan, Frédérique Orsini-Piocelle, Sabine Brechignac, Jean-Richard Eveillard, Karim Belhadj, Marc Wetterwald, Brigitte Pegourie, Arnaud Jaccard, Jean Claude Eisenmann, Sylvie Glaisner, Mohamad Mohty, Cyrille Hulin, Herve Avet Loiseau, Claire Mathiot, Michel Attal
Journal: Blood
Blood (2021) 138 (Supplement 1): 2753.
https://doi.org/10.1182/blood-2021-152136
Published: 2021
Journal Articles

Up-front carfilzomib, lenalidomide, and dexamethasone with transplant for patients with multiple myeloma: the IFM KRd final results

Clinical Trials & Observations
Murielle Roussel, Valerie Lauwers-Cances, Soraya Wuilleme, Karim Belhadj, Salomon Manier, Laurent Garderet, Martine Escoffre-Barbe, Clara Mariette, Lotfi Benboubker, Denis Caillot, Cécile Sonntag, Cyrille Touzeau, Jehan Dupuis, Philippe Moreau, Xavier Leleu, Thierry Facon, Benjamin Hébraud, Jill Corre, Michel Attal
Journal: Blood
Blood (2021) 138 (2): 113–121.
https://doi.org/10.1182/blood.2021010744
Published: 2021
Journal Articles

Acceptable Toxicity and Good Hematological and Renal Responses after Autologous Hematopoietic Stem Cell Transplantation in Multiple Myeloma Patients with Renal Insufficiency at Transplant: A Prospective SFGM-TC Observational Study

Laurent Garderet, MD PhD, Hafida Ouldjeriouat, Mohamed-Amine Bekadja, Elisabeth Daguenet, PhD, Laure Vincent, Damien roos Weil, Marguerite Vignon, MD, Mohamad Mohty, MD PhD, Julie Abraham, MD, Martine Escoffre-Barbe, MD, Bruno Lioure, MD, Redhouane Ahmed Nacer, MD PhD, Denis Caillot, Clara Mariette, MD, Lionel Karlin, MD, Pierre Morel, MD, Lila Gilis, MD, Emanuelle Leray, Anaise Blouet, MD, Nicole Raus, Data Manager, Marie Robin, MD PhD, jean Jacques Boffa, Pierre Ronco, Marie Thérèse Rubio, MD PhD, Jérôme Cornillon, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38–39.
https://doi.org/10.1182/blood-2020-140713
Published: 2020